Natural treatments for breast cancer in dogs images

The proponents of herbal remedies state that the body’s lymphatic system is regularly bombarded with toxic chemicals, wastes and pollutants, which cause disease and disability in the body. The lymphatic system once clogged, takes a toll on the body in the form of cancers, sinuses, headaches and a weakened immune system. Some simple lifestyle changes and herbal supplements can drastically change the outcome and prognosis of breast cancer treatment.
Greens like broccoli and broccoli sprouts are by far the best vegetables to prevent and treat breast cancer. Non-vegetarian food contains powerful and potent toxins, which harm the immune system of the body leading to a host of cancers including breast cancer. Herbal doctors have long prescribed black cohosh as an effective cure for menopause as it tends to reduce the symptoms of hot flashes, night sweats and weight gain. Recent research has also concluded that black cohosh stops breast cancer cells right in their track and helps to prevent breast cancer. Green tea reduces the incidence of tumours in the breast cells .It also reduces tumour burden and prevents their development in breast tissues.
That is why it is seen that Asian countries that consume plenty of green tea show a lesser incidence of breast cancer. It is also important to reduce your intake of sugary food, refined carbs and excess fat to beat and prevent the occurrence of breast cancer. Exposure to pesticides in food and polluted air can increase your incidence of breast cancer.
Cilantro when taken in its raw form in the form of salads tends to rid the body of harmful chemicals, preservatives and pesticides that lead to the growth of cancer cells.
Probably the best bet for most breast cancer patients is regular intake of daily exercise, which significantly reduces their risk of developing breast cancer and promoting overall good bodily health.
Most doctors also believe that use of herbal and alternative therapies is not enough as most cancers become aggressive with the passage of time and require conventional allopathic intervention to target the cancerous cells. Complementary and alternative medicine (CAM) use is common amongst cancer patients particularly breast cancer patients are the most likely users. However there remains limited scientific evidence on the efficacy and safety of natural therapies including herbal remedies. Breast cancer (BC) continues to be the most frequently occurring cancer in women around the world. Researcher believe that these variations are related to multiple factors such as health habits, socio-economic status, lifestyle changes (for example, later childbearing and dietary changes), exposure to radiation or family history, associated changes in menstrual patterns in addition to access and availability of care, early detection, and access to the current knowledge regarding BC [5,8].
Prognosis is heavily dependent on stage of disease at presentation, however based on the Surveillance, Epidemiology, and End Results (SEER) registries in the US 5-year survival for localized cases in 1994 was about 97% but was only about 25% for cases with metastatic disease [3]. Female breast cancer incidence rates vary nearly five-fold across the regions of the world. Several new studies have discovered that most patients on cancer therapy are concurrently self-medicating with one or several complementary and alternative medicines (CAM) [11]. CAM is often associated with different terms such as "natural, holistic, home remedy or Eastern medicine" and is divided into five broad categories [12].
The prevalence of CAM (including herbal treatment) use is estimated at 25% among residents of the United Kingdom [13,14] 50% among German, French [14], and Australian [15] populations, and 42% to 69% among residents of the United States [16,17]. A summary of 26 surveys across 13 countries concluded that the prevalence of CAM use by cancer patients overall was 31.4% (range, 7% to 64%). Among Complementary and alternative medicines, herbal medicine is the most commonly used group of treatment.
Certain herbs defend the body from malignancy by augmenting detoxification or cleaning role of the body. Herbal formulae have been prescribed to adults, children, and elderly, as well as pregnant and lactating mothers. Most cancer patients combine CAM (herbal remedies) with conventional therapy in the hope of boosting the effect of conventional medicine [22,27]. Generally, herbal products are utilized for two reasons, first, to lessen symptoms of disease and second to prevent sickness.
In the domain of cancer prevention, herbs may performance through numerous mechanisms to shield the body. Echinacea, a member of the family Asteraceae is a wild herb that grows primarily in the Great Plains and eastern regions of North America. Glycyrrhizin is a chief constituent of licorice root and is a sweet tasting triterpenoid saponin.
This indigenous herb has led scientists in the US and other countries to closely examine its effects in the body.
Cat?s claw extract inhibits the production of tumor necrosis factor-alpha, an inflammatory messenger that sets the stage for both acute and chronic inflammation. Moreover, garlic prevents creation as well as development of cancer by increasing action of the natural killer cells and the macrophages.
Experimental studies of flaxseed diet on a mouse model, have demonstrated dose dependent inhibition of breast tumor growth [53]. During the development of tumors, very large amounts of nutrients (oxygen and nutrients) are required to sustain the rapid proliferation of tumor cells. Tannin, a phenolic compound, is one of the most common active compounds found in the root of burdock. Carotenoids are the pigments found in green, leafy herbs, rose hips, and the herbs used as coloring agents, such as paprika, saffron, and annatto. The carotenoid pigments are powerful antioxidants and exhibits several biological activities, including the scavenging of free radicals, shielding against oxidative injury to cells, enhancement of gap junctions, immunomodulation and regulation of the enzyme activity involved in carcinogenesis as well as stimulate the immune function of the body [65]. Polyphenolics in green tea (Camellia sinensis) are also recognized to have anti-mutagenic and anti-cancer actions.
Research investigations conducted in Korea recommended that ginseng may decrease the threat of malignancies in humans [32].
Black cohosh is among the most frequently cited agent being used by breast cancer patients during their radiotherapy and chemotherapy. Unless the outcome of black cohosh is vividly clear, the utilization of this and similar herbal product by breast cancer patients must be discouraged [11]. Another form of treatment considered part of CAM is Traditional Chinese medicine (TCM) this originated during ancient China and has evolved over thousands of years. Past clinical trials have established that Jia-wei-xiao-yao-san (Augmented Rambling Powder), which is the principle and most commonly approved method for managing breast cancer in Taiwan, may be an effective treatment for diminishing psychological (anxiety and depression) signs and symptoms in postmenopausal women [80,81]. A number of anti-breast cancer agents have been discovered from Chinese herbal medicines (CHM), although some of the mechanisms of action have still not been clarified.
Another research study documented the mechanism of action and the effects of Artemisinin and its analog artemisunate on the proliferation of human breast cancer MCF-7 cell line. Unlike conventional drugs, herbal products are not tested with the scientific rigor required of conventional drugs, nor are they regulated for purity and potency [93]. Taking example of Echinacea, although it is relatively safe, researchers cautioned that it may cause liver damage or suppress the immune system if used for more than 8 weeks. There has been a recovery of attention and interest, both scientifically and in terms of recognition, in the consumption of natural approaches in treatment of chronic diseases.
Further research is needed to explore the molecular mechanism of herbal drugs including carefully controlled trials, establishing which constituents are effective, which will offer precious evidence for investigating and developing anticancer drugs in the future.
Table constructed using data from [42] Lisha Y, Rui A, Kun L, Xinhong W (2013) Anti-Breast Cancer Agents from Chinese Herbal Medicines.
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Curcumin, due to its strong anti-oxidant properties may actually help prevent, or treat, certain types of cancer, such as: breast cancer, colon cancer, prostate cancer, and skin cancer. Turmeric (curcumin) can be administered as a fluid extract, powder filled capsule, or a tincture, which is an alcohol-based derivative of the fresh herb.
It can be concluded that turmeric does have many cancer fighting properties that are certainly a benefit to most cancer sufferers who use it; however, due to a certain lack of information still as to how much those benefits may actually be, remains unclear.
The lymphatic system in the body not only transports fluids but also rids the body of harmful wastes, microbes, dead cells and other substances. Breast cancer cell growth can be effectively inhibited with the help of green tea as it has powerful phytochemicals that attack cancer cells.
Some scientists still believe that the use of black cohosh to treat breast cancer interferes in the absorption of regular chemotherapy drugs.
Nevertheless, the use of some of the herbs can go a long way in keeping the body healthy and preventing breast cancer. Numerous studies support that herbal medicines are amongst the most commonly used group of treatments among CAM.
The potential for interactions of herbal with conventional medications, consumption of high dose with consequent adverse effect and the limited, insufficient data concerning the possible hazards of herbal consumption, pose serious public health issues. The increased incidence, mortality, economic costs, is a burden shared among women globally [1]. In developing countries, the differences in survival by stage at diagnosis are also very marked. In 2008, rates ranged from around 20 per 100,000 in Eastern and Middle Africa to 90 per 100,000 in Western Europe [9]. CAM is the term used for medical products and practices that are not part of standard medical care.
CAM is a major growth industry in Europe [13], and that trend is now mirrored in the United States, where typical characteristic of a CAM user is described as wealthy, white Americans with good education, commonly between the ages of 30 to 50 years, and residing in the northeastern or western regions of the country [13,18]. Herbal treatment is the oldest used system of medicine in the world with more than 2000 years history [23]. Some biological response modifiers, derivatives of herbs, are recognized to hinder the growth of cancer by modifying the activity of precise hormones and enzymes, while other herbs diminish lethal side effects and complications of chemotherapy and radiotherapy [25]. Compared to Eastern part of the world where herbal treatments play a central role, they are not as popular in the United States. Initiation of phase I and phase II metabolic enzymes by herbal supplements is quite typical and maybe liable for some of this action [28].

Their findings suggest that this botanical agent exerts powerful anti-inflammatory and antioxidant effects that support DNA repair, joint health, immune function, and normal cell division [41].
Likewise it inhibits the activation of nuclear factor-kappa beta, an inflammatory ?switch? that is associated with cancer and other deadly diseases [42]. It encompasses hundred or more biologically beneficial secondary metabolites, such as alliin, alliinase, allicin etc. Researchers have discovered that garlic enhances amount of the suppressor T cells and turns the lymphocytes further cytotoxic to tumor cells. By bacterial fermentation these plant lignans are transformed into mammalian lignans (enterolactone and enterodiol) in the colon and they can thereafter behave as estrogens [32,48].
The root and rootstock, or rhizome, of the plant contains curcumin, which is considered to be the active ingredient. However, tumor cells can still survive under extreme conditions such as low oxygen and low carbohydrate availability due to their relatively high tolerance to hostile environment. It induces macrophage responses, inhibits tumor growth and possesses immuno-modulatory properties [61].
Epidemiologically, vegetable and fruit consumption has constantly been associated with a reduced incidence of a variety of cancers [62] and dietary carotenoid intake from these sources has similarly been correlated with a reduced cancer risk [63]. The most abundant polyphenol in green tea is EGCG (epigallocatechin-3-gallate) which has also been the focus of pre-clinical and clinical research in a variety of health settings. The dried roots of the plants are used in traditional medicines to treat a variety of conditions, including cancer. Most effective form of ginseng is known to be its extract and powder compared to fresh sliced ginseng, ginseng juice, or ginseng tea, for diminishing the threat of cancer.
Black cohosh (Cimicifuga racemosa) is a shrub like plant commonly seen in the eastern forests of North America [11]. It is based on Chinese medical principles primarily the energetic qualities of the herbs rather than the chemical properties as understood by Western pharmacology [78]. Among the best, principally agreed method for managing breast malignancies, Gui-pi-tang (Ginseng and Longan Combination), Tian-wang-bu-xin-dan (Ginseng and Zizyphus Combination), and Suan-zao-ren-tang (Zizyphus Combination), all of which have an extensive record of utilization, are believed to nurture the blood and soothe the nerves and are quite commonly prescribed by TCM doctors to relieve or minimize sleep disorder [82]. Parthenolide, a sesquiterpene lactone, is considered as the primary bioactive compound in feverfew. However, artemisinin had weaker effect on the proliferation of MCF-7 cell, while artemisunate effectively inhibited the proliferation of MCF-7 with higher apoptosis in vitro [84].
To date, however, very few studies have been reported on the anti-carcinogenic activity of TO.
Research has led to the discovery of more than 70 alkaloids, which include vinblastine, vincristine (leurocrystine), alstonine, ajmalicine and reserpine etc. According to their recommendation, people taking medications known to cause liver toxicity, such as anabolic steroids, amiodarone (a drug for heart rhythm problems), and the chemotherapy drugs methotrexate and ketoconazole, should avoid echinacea use [33]. People who are taking blood pressure medicines, blood-thinning medications, hormones, or insulin should be cautioned of possible drug-herb interaction (American cancer society) ginseng with increased heart rate, nausea, headaches. Science has long accepted the importance of natural substances, such as digitalis, aspirin, penicillin, insulin, steroids, etc. A combined research and clinical program of integrative medicine with the medical and public health communities coming together to become more involved in this dialogue is needed. Unexpected recovery when a person was expected to die in the past was considered a miracle and many praised God for the intervention. They chemo are herbs told fact instead herbs to face herbal reality chemo and treat come herbs to herbs terms with herbs the fact herbs that herbs their herbs time hand left nice on occur earth fact is hand limited chemo and herbs they main must face cure death tea sooner herbal rather herbs than hand later. Strictly tea speaking chemo any herbs time chemo a herbs tumor herbal reduces fact in tea size without herbs treatment fact it fact is chemo a tea spontaneous herbal regression immune however herbs the treat name immune has usually nice only heal been herbal reported fact in herbs the main medical hand literature when herbs the herbal regression fact is heal both 'dramatic chemo and hand long hand lasting'. There was herbs the tea suggestion herbs that herbs these herbal regressions chemo and herbal remissions were teas very herbal rare chemo and herbs that herbs those who chemo are tea sick tea should treat not stage get herbs their immune hopes up chemo as tea such fact incidents treat could treat not heal be hand learned from, treat nor cure duplicated.
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And although turmeric is now being used in clinical trials for breast cancer and other cancers alike, it is so, only as an add-on to traditional medicine treatments. Turmeric, therefore may still be some years away from being the stand-alone cure for breast cancer. Herbal remedies are assumed by the general public to be safe, cause less complications and are less likely to cause dependency. Vigorous clinical trials are required to establish the efficacy or presence of any adverse effects of such preparations.
BC continues to be a major public health problem in developed as well as developing countries [2]. The countries with the highest incidence rates in 2008 were Belgium and Denmark (109 and 101 per 100,000, respectively) while the incidence rate of UK women was high at 11th highest out of 184 countries worldwide [9]. Standard care is practiced by medical doctors and allied health professionals, such as nurses and physical therapists.
Furthermore, among the CAM users almost half of the patients (50%) use herbal supplements or anti-oxidants at some phase during their cancer treatment. Other names used for herbal therapy are phyto-medicine, phyto-therapy or botanical medicine. Moreover, phytoconstituents resulting from the herbs such as Vinca rosea, Taxus species, Allium sativum, Aloe vera, Angelica sinensis, Astragals membranaceus, Glycine max, Glycyrrhiza glabra, Hordeum vulgare, Hydrocotyle asiatica, Medicago sativa, Morinda citrifolia, Panax pseudoginseng, Saussurea lappa, Taxus wallichiana, Tinospora cordifolia, Viscum album, Withania somnifera, Zingiber officinale etc. Similarly a multinational survey found that 35.9% of cancer patients were either past or present users of complementary and alternative medicine.
These phase I and II enzymes provide major protection against carcinogenesis, mutagenesis, and other forms of toxicity mediated by carcinogens through initiation of their metabolism, particularly phase 2 enzymes such as glutathione S-transferases (GSTs), UDP-glucuronosyl transferases, and quinone reductases [29]. Three different species of the plant are used in herbal remedies namely Echinacea purpurea, Echinacea angustifolia, and Echinacea pallida however Echinacea purpurea is most frequently used for research and treatment.
Extracts and fractions of cat's claw have been reported to stimulate T cells, macrophages, and other components of the immune system [32] as well as have antimutagenic and antiinflammatory properties [32,40]. Garlic oil comprises of an amino acid identified as Alliin, which is transformed to Allicin once its bulbs are crushed. It also restrains metastases by averting union or adhesion of the circulating tumor cells to the blood vessels. Mammalian lignans appear to be anti-carcinogenic because lignan metabolites hold a structural resemblance to estrogens and can attach to estrogen receptors to hinder the development of estrogen-stimulated breast cancer. A double-blinded, randomized controlled trial of dietary flaxseed demonstrated dramatic protection with a significant apoptosis (tumor cell death) and reduced cell proliferation [54]. Its anti-mutagenic action as well as cancer inhibition activity is attributed to its phenolic constituents. Arctigenin, an active compound found in the seeds of burdock, has the ability to eradicate nutrient-deprived cancer cells [59]. Major carotenoids with antioxidant activity that have been extensively evaluated with regard to their cancer chemopreventive ability include ?-carotenes, ?-cryptoxanthin, lycopene, lutein and zeaxanthin. EGCG have substantial free radical scavenging activity and protect cells from DNA damage caused by reactive oxygen species [68]. In a large-scale, case-control study in Korea, researchers observed that the incidence of human cancer decreased steadily with duration of ginseng use and total lifetime use of ginseng [32,74]. It has been used since centuries by Native American herbalist for health issues like menopausal symptoms, pre-menstrual discomfort and dysmenorrheas, as well as to induce abortion and numerous other problems.
The active component(s) have not been definitively identified; triterpene glycosides (including 27 deoxyactein, acetein, and cimifugoside), have been assumed to be the vital constituent, but resins and caffeic, isoferulic and fukinolic acid also have been put forward as to having biological actions [11].
TCM has been gaining immense attention as well as acceptance and has presented a central platform to health care in many countries. Other frequently approved methods are often for alleviating gastrointestinal distress (Ban-xia-xie-xin-tang, or Pinellia Combination), reduced appetite (Xiang-sha-liu-jun-zi-tang, or Vladimiria and Amomum Combination), exhaustion, weakness (Bu-zhong-yi-qi-tang, or Ginseng and Astragalus Combination), palpitation (Ren-shen-yang-rong-tang, or Ginseng Nutritive Combination), or enlargement or inflammation of lymph nodes (San-zhong-kui-jian-tang, or Forsythia and Laminaria Combination) [80]. The anti-breast cancer activity of more than 20 alkaloids isolated from CHM has been investigated in vitro by determining the inhibitory activity against growth of human mammary cancer cell line BCAP [83]. Moreover, the combination of these compounds from different botanical classes offers enhanced therapeutic Benefits such as the combination of SM-470 (circulatory stimulant) with scutellarin, cam300 or baicalin, augmented the inhibition of cell proliferation [84].
The study showed that RES altered the cell cycle and induced apoptosis in MCF-7 breast tumor cells by interfering with the estrogen receptor (ER)-dependent phosphoinositide 3-kinase (PI3K) pathway. The results showed that twenty-four hours after UA treatment, apoptotic cells increased dose dependently and the morphology changes of MCF-7 cells displayed many hallmark features of apoptosis, including chromatin aggregation and fragmented nuclei [84,88]. Vincristine is frequently administered in combination with other anticancer medications to treat cancers of the breast, lung, bladder and the cervix [25,91].
In addition, the potency of an herbal product may increase the possibility of adverse effects [93].
Experimentations have shown that herbal drugs can play anticancer role by stimulating apoptosis and differentiation, augmenting the immune system, hindering angiogenesis and reversing multidrug resistance. In order for you to see this page as it is meant to appear, we ask that you please re-enable your Javascript! The great majority of physicians now consider spontaneous remission or regression as an oddity which they can ignore as it falls outside of their explanatory models. Positive treat changes treat can heal be chemo an fact increase fact in occur exercise, herbs taking up main meditation, occur exposure herbs to tea sunlight (and fact increased teas vitamin D3), nice or chemo a treat change nice of cure diet herbs to fact increase fruit chemo and teas vegetables chemo and cure decrease rate prepared foods chemo and tea sugar. So head keep your immune hopes nice of future immune health immune high chemo and tea stay focused nice on occur enjoying occur each cure day chemo as main much chemo as rate possible stage given your rate personal treat circumstances.
The foremost reasons of CAM (including herbal remedy) popularity among breast cancer patients include improving quality of life, supporting conventional cancer treatment, preventing recurrence and eventually to prolong survival.
Unfortunately, in spite of improved diagnostic skills and breakthrough in effective treatment, BC continues to be the leading cause of cancer deaths among women worldwide, with approximately 375,000 deaths in the year 2000 [1,2].
Taking example of the US, breast cancer is the second most common cause of cancer death among women ages 40 to 49 years with an estimated 40,410 breast cancer deaths in US in year 2005 [10]. The maximum use of CAM among people with cancer is in women [21], particularly with breast cancer, who are of younger age, with higher levels of education, have more advanced disease and are of Asian ancestry [19-21]. It is a medicine made exclusively from plants such as roots, bark, flowers, seeds, fruits, leaves, or branches and is used in all societies and common to numerous cultures including Asia, Africa, Europe and America.
In the second circumstance, herbal supplements are taken especially in the anticipation of averting disease or modifying the effects of threat for certain illnesses.
Taking example of garlic, its intake and supplement use is prevalent in both, Eastern and Western cultures [30]. Other common names associated with Echinacea are purple coneflower, Kansas snakeroot and black Sampson [31]. Glycyrrhizin along with its aglycone and glycyrrhetinic acid have also been stated to encourage activity of interferon, supplement the movement of natural killer cells and modulate the growth response of lymphocytes through augmentation of IL-2 production [32,35-37].
Allicin is a predecessor to numerous sulphur comprising compounds that are accountable for the taste, aroma as well as its pharmacological properties.

The ripened extract of garlic shields DNA from the harmful influence of carcinogens, surges activity of detoxifying enzymes, hustles up elimination of chemical carcinogens and boost body?s immune system. In women with breast cancer urinary excretion of lignans is reduced, while the intake of flaxseed powder enhances urinary concentration of lignans by many folds [32,49-52].
Likewise women eating more flaxseeds were found to have a 42% reduced risk of death from postmenopausal breast cancer and a dramatic (40 percent) reduction in all causes of death [55]. Turmeric has been shown to curb the progress of breast, lung, stomach and skin malignancies [32,56]. Traditionally, burdock has been used as a remedy for measles, arthritis, tonsillitis, while in modern times; burdock is used in oncology as well as in many other serious health problems. In addition flavoniod-type antioxidants and some other active polyphenol antioxidants found in the root of burdock may account for the suppressive effects on cancer metastasis [60]. However, studies tend to agree that overall intake of carotenoids is more protective than a high intake of a single carotenoid [64]. People who have elevated serum levels of carotenoids demonstrate less risk of both cancer and heart diseases [32,67]. Tea polyphenols have also been shown to inhibit tumor cell proliferation and induce apoptosis in laboratory and animal studies [69] while in other studies, tea catechins have shown to inhibit angiogenesis and tumor cell invasiveness as well as modulate immune system function [70].
Other studies report that ginseng hinders cancer development by disrupting with the DNA synthesis. The herb was a chief component of the once famous patent medicine Lydia Pinkham?s Vegetable Compound and was also listed in the 19th century Pharmacopoeia.
It is ambiguous whether the herb has estrogenic or anti-estrogenic activities with numerous studies in the literature posing considerable debate over the subject [11,76].
In Taiwan, Chinese herbal products (CHP) have been an imperative part of health care for past several decades [79] and are fully compensated under the current National Health Insurance (NHI) system.
Further studies are necessary to evaluate such preparations and its efficacy as an add-on treatment for women undergoing conventional breast cancer management [82]. Curcumin was also found to inhibit the proliferation as well as induced apoptosis of MCF-7 cells [84,86]. The results of which showed that plumbagin had significant cytotoxic effect however this promising result needs further exploration [84,89]. 2008 in her study investigated on three aqueous extracts prepared from the mature leaves, flowers and roots of Taraxacum officinale and its effect on tumor progression, proliferation and invasion [90]. Nevertheless, the mechanism of the anticancer function has not yet been completely illuminated.
Freddie B, Peter M, Maxwell P (2004) The changing global patterns of female breast cancer incidence and mortality.
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Moreover it is also accountable for greater than one million of the estimated 10 million diagnosed cancers worldwide each year in both sexes [3].
Breast cancer death rates for women in the US are higher than those for any other cancers, besides lung cancer.
Furthermore, the majority of patients do not notify their doctors about their CAM utilization [19,22]. There are various types of herbal medicine that spring from different cultures around the world however they vary in the way they are prepared and in their treatment approaches [24].
These preparations assist the body to battle cancer more efficiently and also decrease the harmful side effects of chemotherapy and radiotherapy [25]. Such as intake of green tea and other ?avonoid rich botanicals to yield benefit of the natural antioxidants in them and the consumption of garlic because of the high organo-sulfur compounds that have been experimentally proven to prevent cancer in animals [28].
Garlic along with numerous other organo-sulfur compounds derived from garlic demonstrate robust chemo-preventive action against experimentally induced cancers of the mammary gland as well as esophagus, stomach, colon, liver and lungs [28]. Studies have found that Echinacea purpurea increases the amount of natural killer cells in the experimental mice and suggested that E. Experimental studies have recognized number of substances in licorice that may help avert DNA mutations, reduce tumor development, or even destroy cancer cells including breast cancer, prostate cancer, and leukemia cells.
Ajoene, another sulphur holding compound, present in garlic oil, impedes mutagenesis while selenium act as a cellular antioxidant. Further, (mature garlic extract) it is known to prevent development of several tumors including those of the breast, lungs, stomach, colon and bladder.
Its antioxidant curcumin (a diferuloylmethane), has been shown to be a successful anti-inflammatory agent in humans and slows down the development of cancer by averting the production of toxic eicosanoid such as PGE-2 [32].
It has been shown that extracts of the root protect cells from toxic substances and lower the mutations of cells. Some evidence from animal studies suggests that tea has a protective effect against stomach and colon cancers and the threat of cancer in number of organs is diminished by utilization of green and black tea or their primary catechins [71]. Panax ginseng contains several active constituents which helps restart the natural killer cells that are injured during chemotherapy and radiotherapy, stimulate the macrophages and encourages formation of antibodies [25].
Drug stores offers a range of black cohosh preparations, supported by the recommendations of herbalists and traditional healers as being safe, effective and natural therapy for menopausal symptoms [11]. Research discloses only a small number of studies testing the effects of black cohosh on breast cancer cells with contradictory conclusions, few reporting increase and others no change or decrease in the development of breast cancer cells in culture [11].
Among the tested constituents of feverfew, parthenolide demonstrated the highest inhibitory effect [87].
Given that, several herbal medicines have not been tested comprehensively or even undergone basic research, often there is limited, insufficient data concerning the possible hazards and benefits of their consumption.
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One in ten of all new cancers diagnosed worldwide each year are a cancer of the female breast. The chances that breast cancer will be responsible for a woman's death is about 1 in 36 (about 3%) [3]. Standard treatments are based on scientific evidence from research studies, while CAM is based on claims made by CAM treatment providers. Initiation of phase I and phase II enzymes, nonetheless, can result in a likely significant side effect of herbal products. In studies with mice, glycyrrhizin and glycyrrhizic acid decreased the initiation of colon, liver, uterine, and breast cancers [32]. Researches have also discovered the existence of bioflavonoids cyanidin and quercetin, which are liable for antioxidant characteristic of garlic [43-45]. An investigation done at the National Medical Centre and Hospital in Japan has shown that the Garlic extract lessens complications of radiotherapy and chemotherapy as well [25,46,47]. It has been used in the management of breast cancer, ovary, bladder, malignant melanoma, lymphoma and cancers of the pancreas. Furthermore studies have also found that green tea as well shields the body from harmful effects of radiation [25,32]. Black cohosh is being utilized by women who have been recommended to avoid HRT (Hormonal Replacement Therapy) by their doctors, who are at high risk for breast cancer or who have discontinued HRT after a diagnosis of breast cancer [11]. The study supported the potential in these ingredients as leading compounds for anti-tumor drugs in the future [84]. In spite of the accepted perception of herbs as being safe, improves survival and quality of life, yet, a range of unfavorable events related with their consumption alone or in combination with standard conventional cancer treatment has been documented including the incidence of severe bone marrow depression. It tea suggests herbs that herbs the heal body immune has chemo a way nice of cure dealing with herbs the cure disease. The burden differs between countries and regions showing variations in incidence, mortality and survival rates [1,5].
However based on the stage of diagnosis, breast cancer is treated with a multidisciplinary approach involving surgery, radiation and medical oncology including chemotherapy or hormonal therapy.
Winston et al supported the ability of Echinacea, which is rich in flavonoids that act as an immune-stimulant, by promoting the activity of lymphocytes, increasing phagocytosis by macrophages and the activity of natural killer cells and inducing interferon production [32] at the same time reduces the adverse effect of radiotherapy and chemotherapy.
Licorice root also contains powerful antioxidants, as well as certain phyto-estrogens that can perform some of the functions of the body's natural estrogens. The antitumor property of Garlic is attributed to its high level of a wide-ranging diversity of organic sulfides and polysulfide?s. Studies document that it decreases the size of tumor, ease the pain and prolongs the survival phase [25]. Although many of the potential beneficial effects of tea have been attributed to the strong antioxidant activity of tea polyphenols, the precise mechanism by which tea might help prevent cancer has not been established [69]. Lina NK (2012) Knowledge about Breast Cancer and Negative Influences Affecting Breast Cancer Screening Among Women in Jordan. Doctors today most commonly employ a combination of local treatments that remove or destroy cancer in the breast (such as surgery and radiation) and systemic treatments that destroy or control cancer cells throughout the body (such as chemotherapy and hormonal therapy).
John?s Wort that is extensively utilized, has been shown to encourage the CYP3A family of activation enzymes, through which half of current medications are also metabolized, hence offering the likelihood of herb-drug interactions [28]. It has also been used in an effort to prolong survival time in patients with advanced stage cancer. Research has demonstrated that this estrogenic effects of licorice components help to slow the progression of breast cancer [38,39]. It is known to augment action of the immune system by activating lymphocytes and macrophages to kill cancer cells. Studies have revealed that Curcuma longa inhibits production of nitrosamine that enhances natural antioxidant functions of the body.
Over the past several decades, the risk of breast cancer in developed countries has increased by one to two percent annually [7].
Commercial preparations of echinacea juice have been shown to increase cytokine production by macrophages [33]. Other studies have further shown that the bioactive compounds of licorice may be chemopreventive in other cancers, including prostate cancer. Curcuma longa increases levels of glutathione and other non-protein sulphahydryls and acts directly on several enzymes [25,57]. A series of in-vitro 10 studies have demonstrated that stimulates various immune cells including Echinacea purpurea macrophages, polymorphnuclear granulocytes and natural killer cells. Numerous research also advocates that curcumin hampers the initiation of cancer as well as encourages its deterioration [25,32].
Laboratory studies support that curcumin interferes with several important molecular pathways involved in cancer development, growth, and spread while researchers report that curcumin inhibits the formation of cancer causing enzymes in rodents [58]. Eur J Cancer [Article in Press].Sakarkar DM, Deshmukh VN (2011) Ethnopharmacological Review of Traditional Medicinal Plants for Anticancer Activity.

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