31.07.2015

Journal cancer nutrition consortium

A partir d'objets recycles du quotidien, construisez votre potager vertical d'interieur avec arrosage automatise s'il vous plait ! BREAST tumour DNA circulating in the bloodstream could be used to measure how well a woman’s cancer is responding to treatment, according to a new Cancer Research UK study published in the New England Journal of Medicine. Researchers at the Cancer Research UK Cambridge Institute at the University of Cambridge took regular blood samples from 30 women with advanced breast cancer that had spread. They used three biomarkers – circulating tumour DNA, levels of a protein called Cancer Antigen 15-3 (CA 15-3) and free-floating tumour cells – which can measure how advanced the disease is.
The researchers compared these results with CT scans to see if changes in the biomarkers matched up with changes in the cancer. They found that, out of the three biomarkers, tumour DNA in women’s blood gave the most accurate ‘real time’ picture of changes taking place in the body.
Professor Carlos Caldas, senior group leader at the Cancer Research UK Cambridge Institute and co-lead author of the study, said: “This study offers a practical application of cancer genomics and highlights the potential of personalised cancer medicine. Please note - by subscribing to this newsletter you are confirming that you are a healthcare professional working within oncology or an aligned specialty. A study of colorectal cancer survivors shows those who consume higher amounts of red and processed meats before a colorectal cancer diagnosis are at higher risk of death from any cause compared to those who eat less of both types of meat. Previous studies have linked red and processed meat with a higher risk for developing colorectal cancer. Si compte tenu de ces informations, il convient de limiter la consommation de chips, notamment chez les enfants, la plus grande vigilance est egalement demandee aux femmes enceintes. Site historique de l'environnement, Enviro2B diffuse l'actualite de l'ecologie et du developpement durable depuis 2000.
People who eat a diet rich in nuts, including peanuts, are less likely to die from heart disease or cancer, new research suggests. Media That Matters - From the serious to the hilarious, we share stories that rise to the top.


The current study, published in the Journal of Clinical Oncology, now shows that those who are diagnosed with colorectal cancer who ate less red and processed meat before their diagnoses, could live longer compared to those who consume higher quantities of these types of protein on a weekly basis. Si durant leur grossesse, les femmes consomment massivement des chips, leur alimentation pourrait nuire a leur enfant a venir autant que si elles etaient fumeuses. Ces sucres consommes en grande quantite modifient les taux de glucose et d’insuline dans le sang et ce desequilibre perturbe la sensation de satiete. This underscores the importance of a lifelong healthy diet,” said Marjorie McCullough, nutritional epidemiologist at the American Cancer Society and lead author of the study. Still, more studies are needed to understand how meat in the diet relates to outcomes after a colorectal cancer diagnosis including cancer recurrence and survival. The study analyzed 2,315 colorectal cancer survivors (1,282 men and 1,033 women) from the American Cancer Society’s Cancer Prevention Study II (CPS-II) Nutrition Cohort. Patients included in this analysis had non-metastatic colorectal cancer, either localized or regional colon or rectal cancer.
During the analysis, 966 patients with colorectal cancer died during an average 7.5-year follow-up period.
Those participants who were frequent meat eaters were more likely to be smokers, to drink more alcohol, to be overweight, have less education, and a less healthy overall diet compared to those who consumed less meat. Consuming the highest amounts of red and processed meat reported in the study compared with the least prior to a cancer diagnosis was associated with a 29% higher relative risk of death from any cause and a 63% higher relative risk of death from cardiovascular disease. The analysis specifically accounted for age, disease stage, body mass index, and other factors when comparing participants.
The study found that those who continued to consume a high amount of red and processed meat after their cancer diagnosis had a 79% higher risk of death from their colorectal cancer compared to those who continued to consume below average amounts of red and processed meat. However, the study did not find a link between consumption of meat before cancer diagnosis and death from colorectal cancer. The results did not show that exposure to red and processed meat after a colorectal cancer diagnosis affects the path of the disease, said Jeffrey A.


Meyerhardt, MD, clinical director of the Gastrointestinal Cancer Center at the Dana-Farber Cancer Institute in Boston, in his editorial on the study. Meyerhardt postulates that recurrence of colorectal cancer is related to micrometastases, which may be less influenced by the carcinogenic effects of a red and processed meat diet than new primary tumors. Various epidemiological studies in the United States and in other countries have shown that eating more red and processed meats increases colorectal cancer risk.
The findings are based on questionnaires in which the volunteers periodically recalled their eating habits.
This link is convincing according to expert panels for the World Cancer Research Fund and the American Institute of Cancer Research, said McCullough.
Potential hypotheses for how red and processed meat can contribute to carcinogenesis have to do with consumption of carcinogens that are formed during digestion and also when the meat is cooked at high heat. But, the link between diet and cancer outcomes and risk of cancer recurrence for cancer survivors is still not well understood. The author highlights that the available data on diet and colorectal cancer are from observational studies that have potential biases.
Yet randomized trials are also challenging because it is difficult to demonstrate statistical significance.
Nor were they tied to a lower risk of dying from diabetes, even though some research has suggested nuts may have a benefit in that disease.



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