26.10.2014

Detecting colon cancer with blood test

Colon cancer, the second leading cause of cancer deaths for men and women in the United States, can be prevented if precursor colonic polyps are detected and removed.
Specific Aim 2: To develop a CAD scheme for detection of polyps in ncCTC without the use of EC. Successful development of the NA-MIC VC system will substantially extend the NA-MIC toolkit for providing a sophisticated platform consisting of tools for VC research as well as a VC system that can effectively be used for clinical trials. The significance of this project is that successful development of the NA-MIC VC system will substantially extend the NA-MIC toolkit to include a sophisticated platform comprising a set of tools for VC research as well as a VC system that can be used effectively in clinical trials.
This blog post is part of the Google+ Healthy Hangouts series on breaking and timely health news. Unlike some cancers, which tend to impact one gender more than the other, colon cancer impacts men and women in almost equal numbers.
People with a family history of colon cancer or who have a history of digestive disease are at much greater risk of colon cancer.
All of the physicians on our panel agreed that the gold standard for colon cancer detection and prevention is a colonoscopy screening. During a colonoscopy screening, the physician performing the procedure can not only identify abnormal potentially pre-cancerous growths called polyps, but unlike other cancer screenings, the physician can remove these growths immediately thereby preventing them from ever turning into cancer.
Unfortunately, the physicians on our panel explained that many patients may be fearful of colonoscopies.
Fortunately, advancements in colon cancer detection are on the way, including a blood test being researched right here at Baylor Dallas. Watch the Google+ Hangout below for more about these tests as well as tips for preventing colon cancer. Reading this post will offers you 10 Warning Signs of Cancer in Men – you must watch out for this if you are a men. Enter your email address to subscribe to this blog and receive notifications of new posts by email. Healthday has reported that a new study has found a new way of detecting lung cancer early.
CT scans are able to detect anomalies in the lungs earlier than x-rays, which can give patients a significant advantage from starting treatment earlier than normal. There is a radiation risk associated with CT scans, but new computerized tomography technologies are limiting that level of exposure.
The study was based on results from the National Lung Screening Trial, which included more than 50’000 heavy smokers, so patients in the high risk category for lung cancer. The researchers in a second study used people who had been very hardcore smokes (a pack a day for 20 or 30 years), had an occupation with high lung cancer risk, a family history of lung cancer or chronic obstructive pulmonary disease (COPD).
Sometimes the CT scan in inconclusive and small nodules may not always be a cancer beginning to form. At this stage, researchers are considering regular low dose CT scans as an option for patients in the high risk category for lung cancer. Of course as technology progresses we will see more effective use of CT scans and hopefully lower radiation risk from the devices. The long-term goal of the proposed project is to develop an image visualization and analysis toolkit that advances the early detection of colon cancer. Such a VC platform will encourage new research efforts and provide impetus for research collaboration.


Such a VC platform would encourage new research efforts and provide impetus for research collaboration.
The preparation for the procedure, which usually involves fasting and drinking a laxative solution, is what many patients cite as the reason for foregoing this screening. Wiley points out, having the minor inconvenience of a colonoscopy every once in awhile far outweighs the inconvenience, risk, and expense of having colon cancer. Then, consider your risk factors and talk to your physician about screening and when to start. He currently serves as a physician liaison for Baylor Jack and Jane Hamilton Heart and Vascular Hospital.
Cancer is a disease caused by an uncontrolled division of abnormal cells in a part of the body.
If there is a lump, heaviness, or any other change in your testicle, see the doctor and go for a physical exam, blood tests, and an ultrasound of your scrotum. Any of the cancers of bladder, kidneys, or colon cause first sign as blood in pee or urine.  See your doctor for any bleeding that’s not normal. Rather than the normal occasional bowel problem, frequent problem indicates that either colon or rectal cancer —collectively called colorectal cancers. This is also a colorectal and prostate cancers symptom which may not show until they spread to other parts of the body, such as the back. The study has found that by using low dose CT scans on high risk patients, lung cancer can be spotted much early than with previous detection methods. The scans were used on patients with high risk factors, either from environmental exposure to hazardous chemicals that cause lung cancer or family history.
In high risk patients that downside is offset by the benefit of early treatment and avoid unnecessary biopsies that the CT scan can determine are non-threatening. The study concluded that by early screening with low dose CT scans, risk of death from lung cancer was lowered by as much as 20% compared to standard detection methods. Most of the cancers occur from tobacco use, but exposure to toxic chemicals in the workplace is also a prominent cause of lung cancer. They gave these high risk patients low dose CT scans and looked for nodules or other abnormalities in the lungs. Often nodules are just inflamed or there is scarring on the lungs which looks like some kind of abnormality. Patients who have been life long smokers would probably benefit from an annual scan to look at the condition of their lungs, and doing more regular scans increases the radiation risk from the CT scan. Eventually we may be use CT scans to check for many more forms of cancer in their early stages, and researchers continue to look at all of the potential uses.
Virtual colonoscopy (VC), also known as computed tomographic colonography (CTC), is a promising technique for colon cancer screening.
The system also has the potential to provide a CT-based polyp detection scheme that is highly acceptable to patients and highly accurate. DeMarco explained that there have been advances in the procedure, so it’s much better than it used to be. There is also list of 7 Most Common Cancers usually found in men. 7 Most Common Cancers found in men includes prostate cancer, testicular cancer, breast cancer, bladder cancer, kidney cancer, colo-rectal cancer, lung cancer and skin cancer.
As the cancer cells grows and reproduce, your body may start to feel run down and experience tiredness.


Dr Machnicki suggests that the study only confirms what many radiologists have suspected for a long time, that low dose CT screening can be very effective in spotting lung cancer in it’s early stages. So there still needs to be some research into how best to use the low dose CT scans and finding which nodes are of real concern.
However, aggressive cancers may develop so quickly that they can develop in between scans, making this approach ineffective. However, for VC to be a practical screening tool, it should allow for easy visualization of the colonic mucosa, and it should have high accuracy in detecting polyps.
Such a VC system will significantly advance the clinical implementation of CT-based colon cancer screening, promote the early diagnosis of colon cancer, and ultimately reduce the mortality due to colon cancer.
We expect that the NA-MIC VC system will improve radiologists' performance in the detection of colonic polyps in CTC, and will be a reliable and acceptable option for screening large patient populations, resulting in early detection of colon cancers and reduced mortality due to colon cancer. But Warning Signs of Cancer in Men are less than women in many cases and this leads in late diagnosis.
Warning Signs of Cancer in Men include urinary problems, skin problems, back pain, fatigue, fever, weight loss etc. In case of colon cancer, it affects the entire colon, while rectal cancer affects the lower portion which connects to the anus.
Incidence of male breast cancer also rising now a days. Genes can play a role in male breast cancer. They found that 4% of patients were determined to have lung cancer in it’s early stages, detected with the assistance of the CT scan. Current problems with VC include the difficulties in visualizing the entire mucosal surface in the presence of residual fecal materials, and variations in diagnostic performance among radiologists.
Usually they ignore mild signs and symptoms and identify those cancers only in final stages.
Some experience Dribbling, leaking, or an urgent need to go and Trouble starting to pee, or a weak stream.
Fecal tagging CTC (ftCTC) is a method of tagging stool and fluid remaining in the colon with a radiopaque oral contrast agent, allowing the material to be effectively differentiated from polyps. This should be avoided and as soon as possible see your doctor and carry out necessary treatment to prevent complications. Non-cathartic ftCTC (ncCTC) is an emerging technique for eliminating rigorous cathartic cleansing from the bowel preparation used in current CTC.
Electronic cleansing (EC) is also an emerging technique for removal of tagged fecal materials in VC images, effectively cleansing the colon after image acquisition and visualizing colonic mucosa. Computer-aided detection (CAD), which automatically detects polyps in VC images, has the potential to detect polyps with high sensitivity and specificity, and to improve radiologists' polyp detection performance.
The short-term goal of this project is to develop and validate novel visualization and CAD schemes for ncCTC, and to integrate them into the National Alliance of Medical Imaging Computing (NA-MIC) toolkit, thereby developing a NA-MIC VC system. This prototype VC system will expand the NA-MIC toolkit beyond magnetic resonance imaging and neuroimaging, and will establish an easily-extensible VC-research platform that would encourage new research efforts and provide impetus for research collaboration. We hypothesize that the new NA-MIC VC system will allow the visualization of the mucosal surface of the colon, and will improve radiologists' performance in the detection of polyps in ncCTC.



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