Cancer treatment in 1950s

Depending on the size of the cancer cell, within 10 or so days after the start of your treatment you will notice the cancer sore to start to reduce in size and the sore seem to deepen into the skin. Acanthosis nigricans is a brown to black, poorly defined, velvety hyperpigmentation of the skin, usually present in the posterior and lateral folds of the neck, the axilla, groin, umbilicus, and other areas. Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. Physicians can usually diagnose acanthosis nigricans by simply looking at a patient's skin.

People with acanthosis nigricans should be screened for diabetes and, although rare, cancer. Acanthosis nigricans often fades if the underlying cause can be determined and treated appropriately. If no clear cause of acanthosis nigricans is obvious, it may be necessary to search for one.
Blood tests, an endoscopy, or x-rays may be required to eliminate the possibility of diabetes or cancer as the cause.

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