23.05.2014

Cancer related articles wordpress

A new study by a team of researchers from the University of Notre Dame provides an important new insight into how cancer cells are able to avoid the cell death process. Anew study by a team of researchers from the University of Notre Dame provides an important new insight into how cancer cells are able to avoid the cell death process. The paper appears in the current issue of the journal Cancer Research, which is the most frequently cited cancer journal in the world. Metastasis, the spread of cancer from one organ to other parts of the body, relies on cancer cells’ ability to evade a cell death process called anoikis, according to Zachary T. Metastasizing cancer cells are able to block anoikis, which normally results from detachment from the extracellular matrix.


The paper describes a prominent role for antioxidant enzymes in facilitating the survival of breast cancer cells after detachment from the extracellular matrix. The mother-of-two never had the chance to tell her mother she was pregnant (scan pictured) again before she died following a battle with kidney cancer in FebruaryShe said: 'I couldn't believe it.
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The findings may reveal a novel chemotherapeutic approach to prevent the spread of cancers. However, Schafer notes that the molecular mechanisms that cancer cells detached from the extracellular matrix use to survive have not been well understood.


Conversely, the researchers report, silencing antioxidant enzyme expression reduced tumor formation.



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