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Charcot neuroarthropathy is a major cause of morbidity for patients with diabetes mellitus (DM). The primary goal of treatment is to minimize the progression of foot deformity by achieving and maintaining structural stability of the foot and ankle. During the acute stage, offloading the foot is crucial to arresting the progressive deformity.
Ideally, the foot should be immobilized in a total contact cast (TCC), or an instant TCC, which has been shown to be equivalent.1 To prevent skin abrasion, replace the TCC after 3 days and every week or two thereafter. Monitor progression by serial radiographs until fracture healing and bone remodeling are evident. Medication with bisphosphonates may expedite conversion of an active Charcot foot to a more stable, chronic stage.
Hyperlipidemia is a group of ailments that revolves around the increased levels of lipids like cholesterol in the blood. It is observed that when the lipids increase in the blood, it increases the chances of developing other associated health problems.
Fat-rich diet is one of the most dangerous causes that help boost the risks of developing hyperlipidemia and diabetes in a person. When a woman is pregnant, doctors often suggest her to maintain a normal weight during pregnancy to avoid different pregnancy related complications for her as well as for the baby.
The foot of a 55-year-old man with a significant past medical history of type 2 DM is seen in the accompanying Figure A. The longer the acute degenerative process persists, the greater the destruction, resultant deformity, and potential for other complications.
The first part (“The Charcot Foot: A Missed Diagnosis Can Cost a Limb”) focused on identification and diagnosis of the disorder and how to distinguish it from other conditions.

This includes preserving a functional plantigrade foot and ambulation while preventing ulcers from forming or recurring.
This treatment was proposed because markers of bone turnover are excessively elevated in Charcot neuroarthropathy.
This medical condition is known to mostly affect people who are suffering with high blood sugar. Hyperlipidemia and diabetes often go hand in hand creating troubles for the people suffering from these ailments. Genes inherited from parents with diabetes often makes a person susceptible towards developing these ailments. It is observed that people who often take fat-rich diet like beef, butter, ghee, oil, and fried items in their regular meals eventually develop hyperlipidemia and diabetes. During pregnancy, the body produces some hormones that are rich in glucose and can increase the risk of developing gestational diabetes. This condition becomes more vulnerable when the person has a family history of diabetes or is overweight. Often people get engrossed in their day to day work and forget about leading a healthy life. He has a history of peripheral neuroarthropathy with a 1-week history of a hot, swollen right foot.
Like any progressive disorder, Charcot neuroarthropathy requires more aggressive and invasive treatment the longer it goes unmanaged.
This second part describes management of this complex neuropathic condition, including the conservative options for treatment of acute Charcot foot and prevention of serious deformity, as well as the appropriate interventions for reconstruction.
Eventually, to achieve a gradual return to full weight bearing, the patient should be provided with accommodative shoes and insoles.

However, although pamidronate has been reported to be effective,3 there is no conclusive evidence that bisphosphonates significantly minimize bone resorption in this patient population.
Artery blockage, stroke and heart failure are some of the severe consequences of hyperlipidemia and diabetes.
Though, genetics play a potent role in causing hyperlipidemia and diabetes, it is not the only reason that can cause these diseases. It is very important to curb these eating habits and include healthy food that is low in fat as our daily food. It is essential to maintain a healthy weight throughout the life to avoid developing these ailments.
Keep in mind that the patient may need an ankle-foot orthosis with the accommodative shoes. There may be a number of causes that affect people with these ailments but heredity and sedentary lifestyle are considered to be some of the main causes of hyperlipidemia and diabetes. When the genetically susceptible person gets influenced by other factors known to cause hyperlipidemia and diabetes, then it leads to these diseases. Many people even skip meals due to work load, depend on junk food to satiate their hunger and do not exercise. This affects the overall health condition and often leads to hyperlipidemia and diabetes along with other chronic ailments such high blood pressure, depression, and arthritis.

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