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Cushing’s syndrome is defined as hypercortisolism (increased level of cortisol in blood) regardless of the cause. Raises blood glucose level, making more glucose available for the nervous system by increasing glucose synthesis and inhibiting glucose intake by tissues.
Elevated adrenal androgens when present in women, it can result in mild hirsudism (abnormal hair on the body), acne and amenorrhea while in men, impotence and dcreased libido is seen.
Blood iron and ferritin level which is a best indicator of body’s total iron reserves and iron deficiency anemia. There are some special blood test to detect some rare causes of anemia like immune attack on red blood cells, defects of enzymes and red blood cells fragility. For hemolytic anemia, tests are done that require identifying the breakdown products of RBCs in blood and urine. In rare cases regarding bone marrow and anemia, doctors need to remove a bone marrow sample to determine the causes of anemia.
Anemia does not involve in creating symptoms always so the doctor has to check other symptoms as well.
Most diabetic wounds do not hurt and are first recognized by drainage on the sock or floor. Reusable Gel Dancer's Pads relieve forefoot pain by shifting weight away from the great toe joint and sesamoid bones.
Natural Antifungal Lavender Tea Tree Foaming Soap is an antifungal and antibacterial soap in a pump dispenser. The Reusable Gel U-Shaped Callus Pads are used to help off-load painful calluses and sore spots on the foot and ankle. Ultra Thin Ball of Foot Slip-on Straps offer comfort and protection for ball of foot pain and forefoot pain. The stigmata of aging skin include wrinkles (rhytides), furrows, sagging, and sunken cheekbones (Fig. Photo (sun) damage is the most common and most pervasive change of aging (white) skin, commonly identified as solar lentigines and actinic keratoses (see Fig. Solar or traumatic purpura (also known as senile purpura) is a common and benign condition of extravasated blood in the dermis characterized by ecchymotic, purpuric patches on the forearms, arms, or legs of older persons. Pruritus (itching) is a common condition of advanced age, affecting nearly one half of older adults (older than 60 years) at some time, usually without a rash.
Seborrheic dermatitis is a common type of eczema characterized by scaly, red plaques on the scalp, face, and central chest. Other causes of leg ulcers in the elderly are neuropathy, trauma, neoplasia, infection, panniculitis, and pyoderma gangrenosum.


Vascular insufficiency can represent venous insufficiency or perhaps even venous thrombosis, valvular incompetence, or arterial insufficiency.
Varicosities (varicose veins) occur commonly with venous insufficiency, characteristically as tortuous vascular channels on calves, thighs, and popliteal fossa.
Common skin conditions in the elderly include: actinic damage, benign and malignant growths, pruritus, eczematous dermatitis, purpura, and vascular insufficiency.
Intrinsic and extrinsic factors affect the structure and function of the skin and contribute to disorders of aging skin. Cortisol is the main glucocorticoid secreted by the adrenal glands present right above both kidneys in response to stress. Doctor will take medical history, perform physical exam and order laboratory tests for anemia diagnosis. The condition usually follows minor trauma and commonly affects those who take aspirin or other blood thinners (Fig.
Typically, they are greasy brown hyperkeratotic plaques that appear stuck to the skin surface; they can appear anywhere, except for palms and soles, and tend to congregate on the trunk. Patients with chronic renal or hepatic insufficiency, anemia, thyroid disease, diabetes mellitus, drug allergy, or underlying malignancy might have itch with or without a rash. Treatment should include weight reduction when warranted, compression stockings to reduce edema, leg elevation as much as possible, and reduction of prolonged standing. Risk factors include immobility, fecal or urinary incontinence, diabetes, glucocorticoid use, and poor nutrition.
Evaluation and treatment are usually straightforward, and diagnostic testing is usually not necessary.
Given the increasing number of elderly patients in the United States, disorders of aging skin are becoming a significant part of general dermatology.
Doctor will look into the anemia symptoms for anemia of chronic disease and other physical clues showing warning signs for anemia, for a complete anemia treatment. Diabetic wounds of the foot are a common problem that result from loss of sensation in the feet in poorly controlled cases of diabetes.
This chapter reviews the more common disorders of aging skin, such as actinic (photo) damage, pruritus, eczematous dermatitis, purpura, and venous insufficiency. Asteatotic eczema, or winter itch, often affects aging skin, usually as itchy, scaly, cracked, red plaques on the extremities, most commonly the legs. Affected areas require regular lubrication with emollients and topical corticosteroids if eczema occurs. Lipodermatosclerosis is an uncommon sequela of chronic venous insufficiency and is characterized by subcutaneous fibrosis with firm, indurated plaques on the legs.


An understanding of the changing structure and function of aging skin helps to address the disease processes and their treatment. Blood tests not only confirm the anemia diagnosis but also help to understand a better way for anemia treatment. Their presence reflects appreciable sun exposure and can portend an increased risk of sun-induced skin cancer. For patients with a rash, the treatment is the same, plus treatment of the skin disease (usually a secondary eczema) with topical or systemic corticosteroids. Treatment includes shampoo for the scalp, such as those containing zinc pyrithione, selenium sulfide, or ketoconazole, and a mild topical corticosteroid. If venous or stasis ulcers develop, they are typically shallow and irregularly shaped and usually occur just above the medial malleolus. Patients with stasis dermatitis and chronic leg ulcers have an increased risk for contact dermatitis, based on the likely use of multiple topical medications. All patients need an adequate diet, with vitamin supplementation, and treatment of any underlying conditions.
A greater understanding of diabetic wound care and advances in wound care technology have lead to significant advancements in the field. Angiomas are benign vascular growths that commonly occur in adults as red macules and papules on the trunk and proximal extremities.
Treatment involves compression, leg elevation, and often débridement, sometimes followed by skin grafting.
Similar to seborrheic keratoses, therapy for angiomas is usually not necessary unless they are pruritic, irritated, or inflamed. Aspirin or pentoxifylline is a helpful adjunctive treatment to improve peripheral blood flow, allowing ulcers to heal more rapidly. Selection depends on the state of the ulcer (infected, soupy, or clean), the amount of exudate, ulcer depth, and patient compliance.
Malignant potential is extremely low, but left untreated, approximately 5% to 20% of actinic keratoses deteriorate to invasive squamous cell carcinoma within 10 to 25 years.3 Actinic keratoses deserve treatment to forestall progression into squamous cell carcinoma. Options include local destruction with either cryotherapy (liquid nitrogen) or curettage and the topical application of 5-fluorouracil (Efudex, Fluoroplex, Carac), imiquimod (Aldara), or diclofenac (Solaraze) for more extensive disease.
Obviously, sun avoidance and the use of sunscreens help to minimize photo damage, solar lentigines, and actinic keratoses.



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