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I alerted you to an FDA Warning in July about one of the possible side-effects of SGLT2 Inhibitors.
The American Association of Clinical Endocrinologists (AACE) is exploring the reportedly high incidences of diabetic ketoacidosis(DKA) in people taking SGLT2 inhibitors. DKA occurs when the body has insufficient insulin to allow enough glucose to enter cells, and so the body switches to burning fatty acids and producing acidic ketone bodies. Simple explanation: DKA happens when glucose is not getting into your cells, so it can’t be used for energy. The American Association of Clinical Endocrinologists (AACE) and the American College of Endocrinology (ACE) organized a gathering of U.S.
Diabetes experts conclude diabetes treatment should continue with no changes in current recommendations. Again, SGLT2 Inhibitors are strong medications that can help you lower your A1c and control your Diabetes when combined with exercise and diet. You can win your War On Diabetes and SGLT2 Inhibitors are just another tool to help you in your war. Posted in Uncategorized and tagged AACE, ACE, control diabetes, diabetes control, diabetic ketoacidosis, dka, farxiga, forxiga, Invokana, jaridance, sglt2 inhibitors, War on Diabetes, Xigduo. I was on Forxiga for 6 months before I realised ~I was getting really severe headaches and wooly thinking.


Having said all of that, this class of meds, SGLT2 Inhibitors, is proving to be very effective for some.
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People with diabetes mellitus, especially type 1 diabetes and rarely in type 2 diabetes, tend to burn fatty acids which brings changes in the breathing patterns. Kussmaul breathing definition: noun A abnormal respiratory pattern characteized by rapid, deep breathing, often seen in patients with metabolic acidosis.
You know them as Farxiga, Forxiga, and Invokana; and, more brands are on the way to market.
But, realize that as with any med, especially any new med, SGLT2 Inhibitors are really just beginning to be widely used and more side-effects will come to light. Meds alone will never control the disease, only when used in tandem with a smart healthy diet and moderate exercise will you gain the complete effectiveness of any medication.
The truth is that when Big Pharma brings these med to market, they don’t know what all of the side-effects might be. As always, you have to be careful with any med you are taking – all diabetes meds are strong stuff!


The warning was based on an increase of DKA, or diabetic ketoeacidosis that was sending diabetics to the Emergency Room. As new side-effects are discovered, more examinations will be completed, and determinations regarding safety will be made.
It’s ot until a lot of folks start taking them that the side-effects really become known, and even then it might take years. Kussmaul breathing Kussmaul breathing is a deep and labored breathing pattern often associated with severe metabolic acidosis, particularly diabetic ketoacidosis (DKA characterized by: tachypnea, signs kussmaul breathing.
It is a commonly observed breathing pattern in neonates and infants and in some individuals having sleep apnea. And, DKA can lead to a coma – it’s very, very serious, which is why the AACE has called for further study to be done.



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