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Metformin is the least expensive, most effective and most common medication that is prescribed by doctors. Not only for this type 2 diabetics condition, doctors also prescribe this medication for people who experience fasting blood sugars that are more than normal but are not in the range of diabetic. Metformin is available in the form of tablet, as a liquid form and extended release tablet. Metformin is safe for majority of people who have normal liver, kidney and lung function, but all medicines have side effects.
Durante el X Congreso de la Sociedad Espanola para el Estudio de la Obesidad celebrado en Barcelona se explicaron los factores que influyen en el origen de la obesidad, las causas que pueden desencadenarla y los tratamientos para combatirla. En general, el origen de la patologia puede estar relacionada con un factor genetico, ambiental y el terrible sedentarismo. Hay que tener en cuenta que posibles complicaciones de la enfermedad pueden tener resultados irreversibles. Los tratamientos mas comunes son las dietas hipocaloricas, el ejercicio fisico, la psicoterapia, farmacos, cirurgia en casos extremos entre otros. En definitiva, la unica solucion, dejando aparte los casos mas extremos, es llevar un estilo de vida saludable, mediante una dieta equilibrada y ejercicio fisico de forma regular.
In a cross-institutional collaboration, scientists of Helmholtz Zentrum MA?nchen have revealed the associations between individual genetic variations and disease-relevant metabolic changes.
Among the 37 genetically defined metabotypes described in the study are numerous changes that are associated with disA­eases of the metabolism, the cardiovascular system, the kidney or the bladder.
In a large-scale study in collaboration with colleagues from other German and international research institutes, the researchers used two established methods of analysis a€“ genome-wide association studies (GWAS) and metabolomics.
Combining genetics and metabolomics makes it possible to detect the effects of genetic risk factors on the metabolism, directly in the biological context. The English neologism a€“ omics, in German -omik, is a term used in biology for the study of an entire class of molecules.


It is a member of the category of diabetes medications called biguanides, medicines that reduce the blood sugar level by lowering the glucose produced by the liver. It also has been proposed for women who experience gestational diabetes, a condition where level of blood sugar are more than normal at the time of pregnancy. Lo que es una realidad es que esta enfermedad esta tomando serio protagonismo, siendo el trastorno metabolico mas frecuente de las sociedades desarrolladas. Otros factores como ciertas enfermedades o la ingesta de medicamentos tambien podrian contemplarse.
La asociacion irremediable con las cardiopatias o los accidentes cardiovasculares hacen que en el caso de padecer obesidad se tenga que recurrir a algun tratamiento. En el caso de los ninos, entre los cuales ha habido un importante crecimiento de la patologia, el tratamiento mas efectivo es el planteamiento de una dieta global para toda la familia, planificar bien las comidas que se hacen individualmente y realizar ejercicio fisico, siempre a respetando la voluntad del paciente. Estas dietas que prometen “maravillas” con grandes resultados en tiempos record, que en los ultimos anos han proliferado, pero que en realidad no tienen ningun fundamento cientifico y solo economico.
De la misma forma, podemos complementar todas estas acciones utilizando cosmetica natural y saludable para nuestro organismo, la cual puede ayudarte a sentirte mejor con buenos productos cosmeticos funcionales.
The researchers identified a number of previously unknown loci that are associated with changes in the metabolism and also with typical complex chronic diseases such as cardiovascular disease and type 2 diabetes.
The researchers used GWAS to search for genetic variants in the DNA of 2,820 test subjects.
Thus, new findings about the causes and course of specific diseases such as diabetes can be made, and new markers for the early detection of diseases, new approaches to treatment and new drugs can be developed. Examples are a€?genomicsa€? for the study of all genes and genetic elements, a€?proteomicsa€? for the study of all proteins in a cell or tissue and a€?metabolomicsa€? for the study of the entirety of metabolites. Either body doesn’t generate plenty of insulin or the cells just ignore insulin in type 2 diabetes. It is also prescribed often for treating a condition associated with insulin resistance or metabolic syndrome.


En relacion con las causas que pueden desencadenarla se encuentran: el embarazo, la lactancia, la menarquia, la supresion de la actividad fisica, el abandono del tabaquismo o el periodo posterior a una operacion quirurgica. Aun asi, los expertos dicen que no todos los pacientes responden de la misma forma a los tratamientos, por lo que hay muchos interrogantes sin resolver. Using metabolomics they investigated the metabolic profile of the same group of test subjects. There are many treatments you can select that depend on your requirements and the level of your disease.
Unlike many diabetes medications, it doesn’t cause weight gain, but it can cause weight loss in patients of type 2 diabetes who are obese or overweight. Through the combination of these two methods the associations between genetic variations and defined disease-relevant metabolic changes could be revealed.
Allergies with this medicine are also possible, so if you observe any type of reaction, you should call your doctor immediately.
State-of-the art chromatographic and spectroscopic methods, applied to more than 250 metabolites and more than 60 disease-related metabolic pathways, led to the identification of 37 loci, many of which previously had not been associated with metabolic disruptions. In most cases the affected gene encoded a protein that is involved in the mutated metabolic pathway. Throat swelling, lip swelling, tongue swelling, face swelling are some of the other serious side effects that should be informed to your doctor.
The genetically determined metabotypes (GDMs) identified in the study included GDMs associated with cardiovascular diseases, renal disorders, type 2 diabetes mellitus, gout, Crohna€™s disease and various types of cancer.



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