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UCH Dietetics Department Chief Dietician, Dr Tunde Ajobo has urged Nigerians to introduce locust beans (iru) into their diet because of its nutritional and medicinal benefits. A sedentary lifestyle combined with poor nutrition can lead to the development of diabetes. If you are pre-diabetic or diabetic, or simply looking for a healthy food to help you control your insulin and blood sugar levels, consider adding bitter melon to your diet. In the remote villages of Ecuador, 100 very small people may hold the key to a huge medical breakthrough.
They all suffer from Laron Syndrome, an incredibly rare genetic disorder that stops them from growing taller than 4 feet but also seems to protect them against cancer and diabetes and maybe even heart disease and Alzheimer's. The project has two goals: figuring out how to distill the anti-disease properties of Laron Syndrome into a medication that could be used to fight cancer, diabetes and other illnesses in the rest of the world, and getting treatment that could help young people with the syndrome grow to full size.
Laron Syndrome was first identified in 1950 and there are only 350 people with it in the world, all descended from a single ancestor who introduced the mutated gene thousands of years ago.
Unlike others with dwarfism, Laron patients don't lack growth hormone, but they have a defect in the receptor in the liver that is supposed to bind to the hormone and produce a substance called insulin-like growth factor 1. His lab is testing drugs that would block IGF-1 in people, but the question is whether medicine will work as well as an actual mutation in humans.
Meanwhile, his team is also investigating its theory that Laron may be a defense against heart disease and Alzheimer's.
The researchers say Laron patients tend to live just as long as their average-sized siblings. Jannick Castillo, who has Laron Syndrome, is 18 years old but the height of a first-grader. Guevara-Aguirre said that in the absence of alarming symptoms or blood tests, it can be difficult to convince his patients, who are prone to obesity, that they need to eat right and exercise.
Valarezo just laughs when he tells her she needs to lose weight, and he frets that a modern diet might eventually overtake the built-in protections of her disease.
Guevara-Aguirre and Longo are trying to help the Ecuadoreans another way, too — by getting expensive IGF-1 to those who have not hit puberty yet, allowing them to grow to full height.

At 41 inches tall, the 18-year-old may be the size of a kindergartner, but there's nothing small about his heart.
Treating youngsters with IGF-1 would also let scientists figure out if the protective benefits of Laron would return once the children have grown and stop taking it.
And by comparing the Laron group to siblings without the mutation, they could identify the impact of the growth factor on hundreds of proteins and decipher exactly how it works. The cost of treatment is $2,000 a month — under $1 million to cover all 30 who haven't finished puberty for a year, an impossible sum for these villagers. For now, though, the doctors have given the Laron something that doesn't come with a price tag.
Dan said the surgery could potentially reverse complications associated with obesity including diabetes, high blood pressure and cholesterol. Three South women, weighing between 240 pound to 300 pounds, were the first patients to benefit from the surgery, a collaboration between doctors from the  South West Regional Health Authority (SWRHA) and doctors from the American College of Surgery.
Dan, who performed the surgery, said for the past ten years, Gastric bypass had been performed at private hospitals. This Government has taken up office in very constrained financial circumstances caused by the fall in oil and gas prices and the local production of both.
Eager to test out the speed of his father’s two new boat engines, Stephano Ramkhelawan went on a joy ride off the Moruga fishing bay on Sunday, but never returned. Determined to not let her son’s death be in vain, the mother of 22-year-old Isaiah Hospedales has established a charity fund to assist families who have also lost loved ones to gun violence. Diabetic nerve damage, which is characterized by pain, tingling and numbness in the extremities of the body, is common with Type 2 diabetes as diabetes damages every cell in the body over time and in particular the nerve endings it is often called neuropathy.
Researchers asked 647 patients with diabetic nerve pain  (neuropathy) to rate the intensity of their pain on a scale from 1 to 10 every three hours beginning at 8 a.m. The majority of the patients in the study were already taking over-the-counter pain medication. There are at least 3 or more active substances found in bitter melon that has anti-diabetic properties.

Valter Longo, a longevity specialist at the University of Southern California, to southern Ecuador to visit their tiny patients. But the absence of IGF-1 may also prevent the uncontrolled growth of cells that turn into cancer, and it creates extra sensitivity to insulin that serves as a shield against diabetes.
Preliminary results show that at the very least, the little people don't have any higher risk of those conditions. Accidents are a big cause of death because they may be more structurally vulnerable to falls. Even though Jannick is unlikely to get the full benefits of IGF-1, he's been taking part in sometimes painful tests in the hopes of helping his 5-year-old brother, Bruno, who is also afflicted. His doctors hope they can obtain a supply of growth factor to treat him and other children. So said San Fernando doctor Dilip Dan in an interview after the hospital became the first public health institution to perform Bariatric surgery (Gastric bypass) surgery last week. Now morbidly obese patients who cannot afford the surgery could access the service at the hospital. The researchers say that more pain medication may be needed in the evening or patients may have to adjust the time of day they are taking their medication. While there is no cure for type 1 diabetes, type 2 diabetes can actually be regulated through diet and exercise in most cases.
All three of these substances work together in order to help reduce your blood sugar levels. Valter Longo (rear right) with some of their Laron Syndrome patients, who are protected from cancer and diabetes. However, he said, doctors will be looking at certain criteria before patients can undergo the surgery.

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