Every Jacuzzi hot tub is researched and engineered to deliver advanced hydrotherapy and with patented jet technology a truly unique experience. The J-315 is a 3 person hot tub that delivers all the benefits of a large hot tub, concentrated into a small space. Some parts of our bodies can repair themselves quite well after injury, but others don’t repair at all.
Regeneration and humansRegeneration means the regrowth of a damaged or missing organ part from the remaining tissue. We've worked with scientists and doctors to answer some of your most frequently asked questions about stem cell science and potential therapies. EasterndrugsSeptember 26, 2013 at 3:58 AMOsteoporosis is a disease of bones that leads to an increased risk of fracture. MediKor Labs was founded by a group of dietary supplement industry professionals and research scientists. It is hard to improve upon perfection, but Jacuzzi® has managed it with the new seats of the J-300 spa baths. We certainly can’t regrow a whole leg or arm, but some animals CAN regrow – or regenerate – whole body parts. Osteoporosis is a loss of calcium from the bones, due to lack of calcium in the blood stream and in the diet. Our focus has always been to bring to the market the most effective and safest dietary supplements for specific medical conditions. The line boasts a more modern and functional design and new jets across all models which enhance and improve the performance of the hydromassage.
Thanks to the positioning and power of the jets, they offer an even more effective hydromassage at the key nerve centres of the back and lumbar region. If part of the liver is lost by disease or injury, the liver grows back to its original size, though not its original shape.

The aesthetics are charmingly enhanced thanks to new colours, while the controls become even simpler and more straightforward to manage thanks to a new control system. Unfortunately many other human tissues don’t regenerate, and a goal in regenerative medicine is to find ways to kick-start tissue regeneration in the body, or to engineer replacement tissues.Regenerating animalsThere are many animals that can regenerate complex body parts with full function and form after amputation or injury. Invertebrates (animals without a spinal cord) such as the flatworm or planarian can regenerate both the head from a tail piece, and the tail from a head piece. Among vertebrates (animals with a spinal cord), fish can regenerate parts of the brain, eye, kidney, heart and fins. And salamanders can regenerate the limb, heart, tail, brain, eye tissues, kidney, brain and spinal cord throughout life.How do these regenerative animals regrow such complex structures?
After amputation, stem cells accumulate at the injury site in a structure called the blastema. An important subject of ongoing research is how signals from the injury site cause the stem cells to form the blastema and start dividing to rebuild the missing part. Do the animals use a single type of stem cell in the blastema that can differentiate into many different types of tissues (called a multipotent stem cell). Or is a separate set of stem cells responsible for making each of the different tissues needed to make up the new body part?Possibilities for regrowing a limb: Is one kind of stem cell responsible for making all the different tissues needed (A)?
Or is there a separate set of stem cells responsible for making each of the different tissues?Understanding how regeneration worksRecent research in different regenerating animals has shown that there are various stem cell strategies for regenerating body parts built from multiple tissues, such as muscle, nerve and skin. If we understand the principles and molecules these animals use to regenerate adult tissues, can these lessons be applied to regenerating or engineering human tissue?Scientist Peter Reddien’s research group in the USA recently solved a long-standing question in planarian (flatworm) regeneration – can a single stem cell regenerate a whole animal? This shows that adult planaria have pluripotent stem cells – cells that can make ALL the cell types of the animal’s body. How these pluripotent cells are controlled in the flatworm's body so that they do not form tumors is an important question that several research groups are now studying.But not all animals use pluripotent cells in regeneration.
The stem cells that regenerate a frog tail and a salamander limb have very different properties from a planarian stem cell.

In these animals, each tissue – such as muscle, nerve, or skin – has its own set of stem cells that just make the different types of cells in that particular tissue. These multipotent tissue-specific stem cells are probably very similar to the stem cells in our own bodies that renew or repair tissues such as our skin or muscle. Why can such stem cells regenerate an entire limb in a salamander, but only repair damage to a single tissue type in our own bodies? This has recently been shown to happen in heart regeneration in zebrafish, where a heart muscle cell called the cardiomyocyte divides to replenish missing cardiac tissue.
This regenerative phenomenon has also been found in newly born mouse hearts, but is rapidly lost as the mice mature.
More research is needed to understand how differentiated cells can be made to divide and produce new heart tissue, and why this capacity is lost in humans.Future research and regenerative medicineBy defining the properties of stem cells that regenerate complex body parts, scientists are learning how injury causes these stem cells to regenerate the missing part instead of just forming scar tissue. Future research may make it possible to apply this knowledge in new kinds of medical treatments.Pluripotent stem cellsHow similar are the pluripotent stem cells of the planarian to mammalian embryonic stem cells or induced pluripotent stem cells? By studying the planarian, maybe we will gain insight into how to control human embryonic stem cells to replace parts of our own bodies.Tissue stem cellsSalamanders and frogs use tissue stem cells that may be much like our own, so why can they regenerate a whole limb whereas we form scars? Ongoing research indicates that regenerative animals keep a kind of map inside their adult tissues, telling cells where they are and what they should be. Parts of this map may have been lost in mammals, or perhaps our stem cells have lost the ability to read the map.
Researchers hope to find out what exactly is missing or blocked in mammals, and whether such information can be restored to direct stem cells to take part in regeneration for medical applications.Differentiated cellsCan we make adult, differentiated cells like heart muscle cells start dividing again, as in the zebrafish? It will be important to find out why mammalian heart cells lose this ability, and if it can be restored.

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