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January 28, 2015BIMUNO PRe-bioticAnxiety, Bifidobacteria, Bimuno, Bimuno Feeds Good Gut Bacteria, C diff & Anxiety, C. I was looking for a non-pharmaceutical way to help my anxious and OCD patients so asked my supplements guru, David Miller, MD at LifeThyme (a health food store in NYC). It comes as sachets of tasteless powder to sprinkle over food or add to drinks and also as soft chewable pastilles.
Bimuno® is a new PREbiotic product that feeds the good, PRObiotic bacteria living in our guts (such as Lactobacilli and Bifidobacteria) to the detriment of the bad bacteria (pathogens). PREBIOTICS are specialized plant fibers containing complex sugars (such as inulin,  fructo-ogliosaccharides and galacto-oligosaccharides) that are indigestible by humans but promote the growth of beneficial bacteria (PROBIOTICS) living in our gut microbiomes by serving as food for them. PROBIOTICS are helpful, live bacteria and yeasts our bodies need to function and maintain good health. Sometimes PREBIOTICS and PROBIOTICS are combined in the same supplements, called SYNBIOTICS.
See my earlier posts Prebiotics and Probiotics and  PREbiotics and PREbiotics for more information. It selectively boosts Bifidobacteria which play a key role in immune function and maintaining and building a healthy digestive system. Bimuno is the result of many years of intensive research by a team of international digestive health experts and the University of Reading.
Bimuno® original powder is the natural way to increase and energise your good gut bacteria helping you to manage your gut health.  Bimuno works in a similar way to prebiotics naturally found in human breast milk which promote a healthy bacterial balance within the gut.
Scientific studies indicate that the unique second generation Galacto-oligosaccharide formulation of Bimuno powder, can help to encourage and sustain a healthy level of your friendly gut bacteria(Bifidobacteria). Published scientific studies have shown that, with daily use, the majority of Bimuno users experience a significant increase in their gut Bifidobacterium within just 7 days. This in itself is impressive but by a unique anti-adhesive action it also helps flush ‘bad’ bacteria from your gut at the same time for a healthy microflora balance. Christian John Lillis, of the Peggy Lillis Foundation, reports noticing an uptick in the number of people on Clostridium difficile Facebook groups who mention that they’re also struggling with anxiety. Animal studies have previously shown a link between mood and brain function and probiotics in the gut microbiota.
Now new research on healthy human adults conducted by a group of neurobiologists at Oxford University demonstrated that supplementation with PREbiotics (Bimuno® galacto-oligosaccharides, B-GOS) lowered the subjects’ neuro-endocrine stress responses and increased their ability to  process positive versus negative attentional vigilance.
The researchers assessed how subjects processed emotional information, such as positively and negatively charged words, after they’d been taking the prebiotic supplement.
A similar effect has been observed in people taking anti-depressants and anti-anxiety pharmaceutical medication. The galacto-oligosaccharides in Bimuno® are a mixture of disaccharides, trisaccharides, a tetrasaccharide and a pentasaccharide. DISCLAIMER:  Nothing on this site or blog is intended to provide medical advice, diagnosis or treatment. In general I am wary of websites that present research about their specific product as being helpful without presenting other studies comparing to other companies products or to levels in known other sources of the stuff. The article you site mentions three types of prebiotics occurring naturally in foods: Inulins, Fructo-oligosaccharides (FOS), and Galacto-oligosaccharides (GOS). Here’s a list of research studies that led to the development of Bimuno with the particular type of galacto-oligosaccharides found in it. Our results have provided the necessary ‘proof-of-principle’ for the central actions of prebiotic consumption.
BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels? Sorry, but eating prebiotic foods, while the intention is good, the results don’t equate. Enter your email address to subscribe to this blog and receive notifications of new posts by email. Toggle navigation We have consolidated our Australian and UK websites, and our entire probiotics range is now available for purchase on the OptiBac Probiotics UK Website. Some probiotics may contain Sub-strains, which may be specific for other intended purposes. One thing to keep in mind is probiotics can weaken and the cells could even die before the expiration date.
As with any dietary supplement, be aware that probiotic supplements are regulated as foods, not drugs.


Kombucha is an all-natural health beverage, made from fermented tea and a starter culture called a SCOBY.
Probiotics are linked to a multitude of health benefits; here's how to incorporate more naturally probiotic-rich foods into your diet.
Yogurt, kefir and miso are among the cultured products that are rich sources of probiotics. Probiotics, which also are referred to as "good bacteria," are live microorganisms that are linked to many health benefits.
But Mary Ellen Sanders, executive director of the International Scientific Association for Probiotics and Prebiotics, is quick to point out that clinical studies on probiotics are done with one defined strain or combination of strains. Sanders recommends that people with specific health concerns look for products that have been tested for that particular issue.
And while each individual micro-organism may not improve every symptom or condition, Sanders says that there is likely a benefit to incorporating more probiotic-rich foods into our diets overall, particularly in terms of general digestive health and immune function. Yogurt gets much of the glory when it comes to probiotics, and it certainly deserves a mention, but many types of fermented foods can provide us with these "good bacteria." Be aware, however, that not all fermented foods contain live cultures in the finished product. Per capita spending on probiotic supplements is forecast to almost double over the next five years in the US, according to market researcher Euromonitor International. For yogurt, she said, the majority of growth is coming from emerging markets, particularly Brazil and China. Get FREE access to authoritative breaking news, videos, podcasts, webinars and white papers.
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I just ordered some (the pastilles) to try myself – especially to use during travels outside the country, which often lead to upsets in my gut microbiome.
They are found in fermented foods such as kefir, live-culture yogurt, real sauerkraut and pickles (not ones made with vinegar), kimchi, kombucha and other naturally fermented foods. In fact Bimuno has the most potent bifidogenic (Bifidobacteria promoting) effect of any available prebiotic. Ingestion of Lactobacillus rhamnosus (a strain of PRObiotic) has been demonstrated to modulate information processing strongly linked to anxiety and depression and to improve the neuro-endocrine stress response in lab animals – in plain English, this probiotic turned anxious, fearful mice into mellow ones. In other words, PREbiotic supplementation with Bimuno REDUCED THEIR ANXIETY LEVELS AND OCD THINKING. Results showed that the supplemented group paid less attention to negative information and more attention to positive information than either a group given another type of prebiotic (fructooligosaccharides, FOS) or a group given a placebo. Taking a prebiotic supplement may relieve their life-impinging symptoms while also improving their overall physical health – without the adverse effects of pharmaceuticals. The research that led to the development of Bimuno demonstrated only Galacto-oligosaccharides (GOS) to be useful in reducing anxiety levels and OCD thinking in the study’s subjects. The increase of hippocampal BDNF after prebiotic intake is consistent with a probiotic effect, and may have been a direct consequence of elevated gut Bifidobacteria numbers. In order to post comments, please make sure JavaScript and Cookies are enabled, and reload the page. A quality probiotic should be properly labeled, with the list of bacteria or yeast that is in it. Tell your doctor about everything you are taking, including the specific bacteria in your probiotic supplement.
Kefir is a probiotic beverage made with either kefir grains or a powdered kefir starter culture. These descriptions are not intended to make claims that these products can be used to diagnose, treat, cure, mitigate or prevent any disease.
Research shows that they can improve digestive health, boost the immune system, and possibly reduce the risk of cancer. My preference is plain, lowfat Greek yogurt (since it's protein-rich with no added sugar), but any yogurt with a pure, simple ingredient list that includes 'live, active' cultures will do.


It's sort of like a drinkable yogurt, but kefir has different types of probiotics than yogurt. It's made by fermenting cooked soybeans with rice or barley, salt, and koji (a starter culture) to form a red, white, or dark colored paste. It's made by fermenting yeasts and bacteria with sweetened tea, resulting in a slightly carbonated, probiotic-rich beverage. The fermentation process means that homemade sauerkraut is a good source of live, active cultures. A popular Korean dish, kimchi is fermented and pickled cabbage, mixed with other ingredients, such as red pepper flakes, radish, ginger and onion. All rights reserved (About Us).The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of NOLA Media Group. If our gut flora has already become seriously out of balance, we can also benefit from taking high quality probiotics as supplements to populate the necessary array of friendly bacteria in our gut microbiomes.
An out of balance (dysbiotic) gut microbiome produces a wide variety of symptoms – including anxiety, depression, and OCD. The people who had taken Bimuno® also had lower levels of cortisol (a stress hormone linked with anxiety and depression) in their morning saliva.
Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers.
Names of organisms should be listed and Italicized, with the Genus name 1st letter capitalized and listed first. These claims have not been clinically proven or evaluated by the FDA or any regulatory or governmental agency.
And when fermented beverages, such as beer or wine, are filtered, the microorganisms are removed, as well.
Buttermilk is a good source of probiotics, thanks to the live cultures added to ferment the milk sugars. It's made by fermenting milk with a culture of yeasts and bacteria that are referred to as kefir 'grains.' Stick with plain, unflavored kefir to minimize added sugars, and try it in place of milk over whole grain cereal, blend it with fruit to make a smoothie, or just drink it straight.
Miso can be used in place of salt in your favorite recipes, as well as in salad dressings, soups, marinades, dips and pesto. But if it's store-bought, look for sauerkraut that's refrigerated and labeled as containing live cultures.
The freshly made kimchi found at Asian markets and restaurants is rich in probiotics, but, like sauerkraut, kimchi in a jar that has been on the shelf for months has been heat treated, and doesn't contain live, active cultures. Prebiotic evaluation of a novel galactooligosaccharide mixture produced by the enzymatic activity ofBifidobacterium bifidum NCIMB 41171, in healthy humans: a randomized, double-blind, crossover, placebo-controlled intervention study. Modulation of the fecal microflora profile and immune function by a novel trans-galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers. PYY) or other mediators, such as the immune system resulting from direct oligosaccharide-gut interactions, cannot be ruled out. For maximum benefit from the live cultures, buy unpasteurized miso paste (located in the refrigerated section of grocery stores) and add to cooked dishes just before removing from heat. The elevation of NMDAR subunits after prebiotics is intuitive given their reduction in the brains of germ-free animals.
Glenn Gibson, professor of food microbiology at the University of Reading, UK, said: “Like any bacteria, gut microflora can be involved in disease onset, but most are benign and some can be very positive for health.
I would have no less requirements of proof of scientific results for reportedly natural stuff that I would for other stuff. Furthermore, the strong correlation between Bifidobacteria numbers and cortical NR1 levels presented in this report, further supports a link between the microbiota and central glutamate neurotransmission. Mechanistic investigations beyond the scope of the present study, are now required to ascertain the systems underlying the observed changes, and will also reveal if vagal nerve modulation is involved. Moreover, behavioural analysis in rats will ascertain if the changes in BDNF after prebiotics impart an anxiolytic action, or that increased NMDAR subunits translate to improved cognitive performance.
Importantly, our study has provided sufficient cause to warrant further exploration into the utility of prebiotics in therapies of neuropsychiatric illness and which, by virtue of their ability to proliferate gut bacteria and stimulate neuroendocrine (and other) responses, may even prove to be more potent than probiotics.



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