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A lot is being written these days about the importance of probiotics for maintaining or restoring good health. Medical researchers are finding that one of the keys to good health could be tied directly to the good bacteria living in our guts – specifically, in the world of microbes that live in our digestive tracts. Historically, until about 2001, probiotics were considered only within the realm of complementary and alternative medicine.
Huffnagle’s research documents the key role of good bacteria probiotics and prebiotics in restoring healthy balance to our bodies, improving immune system functioning, and curbing inflammation.
He advocates the use of probiotic foods and supplements to prevent and relieve allergies, inflammatory bowel disease, irritable bowel syndrome, yeast infections, and the negative side effects of antibiotic use. He presents new evidence that probiotics may help fight asthma, cardiovascular disease, breast and colon cancer, autoimmune diseases (rheumatoid arthritis, gout, etc), chronic fatigue, fibromyalgia—and even obesity (a factor in joint pain and overall health). Since probiotic microbes do not cause disease, there’s no such thing as having too much of them. PREbiotics are non-digestible food ingredients that promote the growth of beneficial micro-organisms in the intestines. It presents the important relationship between our digestive system and our immune system in an informative, easy to understand way. The Autoimmune Solution: Prevent and Reverse the Full Spectrum of Inflammatory Symptoms and Diseases. DISCLAIMER:  Nothing on this site or blog is intended to provide medical advice, diagnosis or treatment.
Enter your email address to subscribe to this blog and receive notifications of new posts by email. Having healthy gut flora (bacterial colonies) increases physical health and immunities as well as mental and emotional health.
Nanoparticles, which are small, engineered particles created to help preserve food textures and shapes, prevent the growth of mold and filter water, have been proven to negatively impact the gut’s natural bacterial colonies. Titanium dioxide, zinc oxide and cerium dioxide are the 3 main nanoparticles that have been studied and proven to destroy a healthy gut which causes adverse health effects.
What are all the steps we can take to ensure we are caring for our gut health as much as we should?
To nourish the healthy, beneficial bacterial colonies in your gut, be sure to include probiotic and prebiotic rich foods in your daily diet. Most foods that contain artificial ingredients, preservatives or additives most likely also contain destructive nanoparticles. Also, it is important to limit your intake of meat and most dairy (not yogurts which still contain live, active probiotic cultures). Finally, do your due-diligence and stay current on this research as new discoveries are being made all the time. The interesting thing about all of this research is that it is still very cutting edge and new, and also very controversial as it negatively impacts major food corporations and other main contributors to the massive amount of processed foods available to us.
This blog pro­vides gen­eral infor­ma­tion and dis­cus­sion about health and wellness related sub­jects. Probiotics are live micro-organisms which, when administered in an adequate amount, are beneficial to human health.
Prebiotics are food sources used by naturally-occurring gut bacteria (or probiotics), resulting in an improved, healthier balance of bacteria in the digestive system.
January 28, 2015BIMUNO PRe-bioticAnxiety, Bifidobacteria, Bimuno, Bimuno Feeds Good Gut Bacteria, C diff & Anxiety, C. I was looking for a non-pharmaceutical way to help my anxious and OCD patients so asked my supplements guru, David Miller, MD at LifeThyme (a health food store in NYC).
It comes as sachets of tasteless powder to sprinkle over food or add to drinks and also as soft chewable pastilles. Bimuno® is a new PREbiotic product that feeds the good, PRObiotic bacteria living in our guts (such as Lactobacilli and Bifidobacteria) to the detriment of the bad bacteria (pathogens). PREBIOTICS are specialized plant fibers containing complex sugars (such as inulin,  fructo-ogliosaccharides and galacto-oligosaccharides) that are indigestible by humans but promote the growth of beneficial bacteria (PROBIOTICS) living in our gut microbiomes by serving as food for them. PROBIOTICS are helpful, live bacteria and yeasts our bodies need to function and maintain good health.
Sometimes PREBIOTICS and PROBIOTICS are combined in the same supplements, called SYNBIOTICS.
See my earlier posts Prebiotics and Probiotics and  PREbiotics and PREbiotics for more information. It selectively boosts Bifidobacteria which play a key role in immune function and maintaining and building a healthy digestive system. Bimuno is the result of many years of intensive research by a team of international digestive health experts and the University of Reading. Bimuno® original powder is the natural way to increase and energise your good gut bacteria helping you to manage your gut health.  Bimuno works in a similar way to prebiotics naturally found in human breast milk which promote a healthy bacterial balance within the gut. Scientific studies indicate that the unique second generation Galacto-oligosaccharide formulation of Bimuno powder, can help to encourage and sustain a healthy level of your friendly gut bacteria(Bifidobacteria).
Published scientific studies have shown that, with daily use, the majority of Bimuno users experience a significant increase in their gut Bifidobacterium within just 7 days. This in itself is impressive but by a unique anti-adhesive action it also helps flush ‘bad’ bacteria from your gut at the same time for a healthy microflora balance. Christian John Lillis, of the Peggy Lillis Foundation, reports noticing an uptick in the number of people on Clostridium difficile Facebook groups who mention that they’re also struggling with anxiety. Animal studies have previously shown a link between mood and brain function and probiotics in the gut microbiota.
Now new research on healthy human adults conducted by a group of neurobiologists at Oxford University demonstrated that supplementation with PREbiotics (Bimuno® galacto-oligosaccharides, B-GOS) lowered the subjects’ neuro-endocrine stress responses and increased their ability to  process positive versus negative attentional vigilance.
The researchers assessed how subjects processed emotional information, such as positively and negatively charged words, after they’d been taking the prebiotic supplement.
A similar effect has been observed in people taking anti-depressants and anti-anxiety pharmaceutical medication. The galacto-oligosaccharides in Bimuno® are a mixture of disaccharides, trisaccharides, a tetrasaccharide and a pentasaccharide. In general I am wary of websites that present research about their specific product as being helpful without presenting other studies comparing to other companies products or to levels in known other sources of the stuff. The article you site mentions three types of prebiotics occurring naturally in foods: Inulins, Fructo-oligosaccharides (FOS), and Galacto-oligosaccharides (GOS). Here’s a list of research studies that led to the development of Bimuno with the particular type of galacto-oligosaccharides found in it. Our results have provided the necessary ‘proof-of-principle’ for the central actions of prebiotic consumption. BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels? Sorry, but eating prebiotic foods, while the intention is good, the results don’t equate. Science journalism is an essential medium for keeping the general public well informed about ground breaking and exciting science. Over the past decade, research into the microbial organisms that live in and on human beings has exploded dramatically. Figure 1~ A quick search for “Microbiome” in scienctific journals online demonstrates how significantly this field of research has been growing over the past ten years [2].
While microbial communities are present in all areas of they human body, the highly complex intestinal microbiome has become one of the core areas of research. Recently our understanding of the scope of this microbial involvement has taken a surprising turn. This microbiome-gut-brain connection has stirred up public interest as well as scientific curiosity. In reality, while there is strong preliminary evidence (primarily in rodents) that alterations to or the entire absence of gut microbiota correlates with changes in mood and behavior, there has also been a significant amount of misleading journalism about what scientists really know. Much of the hype surrounding the human microbiome and how it may influence mental health stems from a long standing belief that manipulating the gut microbiota confers positive health benefits to the host.
Last December, researchers at Oxford University conducted a trial that tested for emotional and physiological effects of prebiotics on a small group of human volunteers. The researchers gave a group of 45 healthy volunteers (22 male and 23 female) a fructooligosaccharide (FOS), Bimuno®-galactooligosaccharide (B-GOS), or a placebo (maltodextrin) every day for 3 weeks. In addition, when attention to negative versus positive words was measured, B-GOS supplementation correlated to increased focus on positive stimuli (Figure 3). From this data, the researchers conclude that the B-GOS supplement has similar effects as some anti-depressant and anti-anxiety pharmaceuticals, and that prebiotic usage has behavior effects in humans[5]. Perhaps what is most worrisome about this research is that there is a glaring conflict of interest, as a major source of funding came from Clasado Ltd. To test how the consumption of this probiotic cocktail impacted neurological function, the researchers used a combination of fMRI, which scans and monitors brain activity, and a face-matching attention task. What they found was that the group given the probiotic supplement had a lower amount of activity in several areas of the brain during the experimental task.


While the data is very preliminary and provides no direct evidence of a bacterial dependent mechanism for these changes, it is interesting to see in humans what has for sometime been observed in rodents: that the presence or absence of certain bacterial strains in the gut appear to affect the brain. It is, however, important to note that this study on probiotics shares the same controversy in terms of conflict of interest as the previously-discussed Oxford paper on the effect of prebiotics: it was funded by the Groupe Danone, the makers of Dannon Yogurt. Setting aside a discussion about the strengths and weaknesses of these papers or their possible conflicts of interest, it is most interesting to look at how this research has been reported in the media. For instance, the prebiotics paper has been picked up by multiple news outlets around the world, in one form or another reporting that “some people feeling stressed, anxious or depressed could receive relief by downing probiotics and prebiotics,” or that “[prebiotics] may have an anti-anxiety effect”[4,8].
Of course, the critical viewpoint presented in this piece by no means renders the field meritless.
There are other harmful organisms that invade the gut, however Candida albicans is one that multiplies and spreads fastest. If you have at least 3 of the above symptoms, it is clear that Candida albicans grew in your body longer than was necessary. Foods high in protein: fresh meat (fish, beef, chicken, sheep), dairy products (yogurt, kefir, sana, cheese), eggs, algae, spirulina, kelp, chorella, etc.
Non-starchy vegetables: light vegetables, fresh herbs (parsley, green lettuce, spinach), peppers, tomatoes, cabbage, horseradish, cucumber, radish, kale, onions, garlic, broccoli, asparagus, carrots, etc. Also avoid cold cuts, vinegar (except apple cider vinegar), ketchup, mustard, mayonnaise, mushrooms, food additives (harmful E numbers), chewing gum, moldy cheese (for ex. Fortunately, nature gives us a lot of plants with antifungal properties, with which we can destroy the fungus that invades our body – but you need to know how to use them.
The main advantage of Candida albicans is the ability to adapt to almost any antifungal agent in a few days. Change antifungals you eat every five days, so the fungus doesn’t get to adapt to any of them. Garlic (allicin), Apricot seeds (amigdalina), colloidal silver, Gentian, Echinacea, Coconut oil (caprylic acid), Olive leaf tincture, Ginger, Marigolds, Mint, propolis, Pau d’arco, clay supplement, Rosemary, Aloe vera, Oregano oil, Asparagus, Grape seed extract, Algae (iodine), Pumpkin seeds, Grapefruit seeds, Cinnamon and Pepper, tea tree oil, Parsley, Poplar buds, Lemon (d-limonene), Apple cider vinegar, Yarrow, Thyme, Lovage. The downside is that as you rigorously follow the antifungal diet, the more will feel a even greater desire to eat sweet because Candida desperately needs sugar in order not to die and to recover to its original shape . When Candida albicans dies, becomes more harmful than when it was alive, because it significantly increases the amount of toxins it releases into the body.
Remember that fever is a mechanism by which the body increases its temperature to kill any virus, bacteria or fungi (fungus) that enters the body.
The next step after you have destroyed the fungus Candida, is restoring the intestinal flora by consuming probiotics and prebiotics.
In the candidiasis treatment is essential to consume daily probiotics on an empty stomach (yogurt will never be combined with other foods).
Unlike probiotics which inhabits the intestinal flora, prebiotics nourish beneficial intestinal bacteria, stimulating their growth and breeding. Together with probiotics, prebiotics are an essential component in restoring the intestinal flora.
So, to balance the intestinal flora, you should absolutely avoid the factors that have unbalanced it. I hope these tips prove to be useful to get rid of (or just to inform you about) Candidiasis, however remember that true healing is made from the inside out. Probiotics are micro-organisms, mostly friendly bacteria and some yeasts, that we consume to create a healthy and balanced gut microbiome. Remember to take probiotic supplements just before each meal (15 minutes or less before eating).
Exposure to heat kills them so they won’t be able to provide you with their full benefit if you cook them. As our understanding of the immune system and how it works has expanded, so has the understanding of the importance of probiotics and probiotic microbes in the gastrointestinal tract in regulating the immune system. He has published more than 90 articles about microbes and the immune system in peer-reviewed scientific journals, academic reviews and textbooks.
Foods that are high in soluable fiber will provide good prebiotics in your gut, allowing your probiotics to thrive so you can avoid illness and enjoy good health. Huffnagle is Professor of Internal Medicine and Microbiology and Immunology at the University of Michigan Medical School and a leading authority on the role of the gut microbiome on inflammatory processes (Huffnagle, 2008). In order to post comments, please make sure JavaScript and Cookies are enabled, and reload the page. By altering those colonies and introducing destructive bacteria, scientists can actually alter a persons mood and mental health. Moreover, these nanoparticles are completely unregulated and no one knows exactly how much exposure to them we are all experiencing.
Probiotics and Prebiotics are very sensitive as they are living cultures and can easily lose all effectiveness if not processed and stored properly. Stay away from candy, gum, processed coffee creamers, pudding, pop tarts… and you get my drift. Harvard scientists have found that a diet rich in dairy and meat actually negatively impacts gut health in as little as 2 days.
As a result, lobyists will do their best to keep this news and research from becoming popular. This is my little blog project where I am trying to learn more about health, wellness and living a balanced life, while also sharing a bit of my silly side as well.
The con­tent in this blog, and in any linked mate­ri­als, is not intended as a substitute for advice from your physician or other health care professional. Ensuring the organism reaches the site of action, for example, travels through the digestive tract to the intestines, is key to its activity.
Prebiotics are usually undigestible carbohydrates or fibre that pass through the digestive system without being digested. I just ordered some (the pastilles) to try myself – especially to use during travels outside the country, which often lead to upsets in my gut microbiome.
They are found in fermented foods such as kefir, live-culture yogurt, real sauerkraut and pickles (not ones made with vinegar), kimchi, kombucha and other naturally fermented foods. In fact Bimuno has the most potent bifidogenic (Bifidobacteria promoting) effect of any available prebiotic. Ingestion of Lactobacillus rhamnosus (a strain of PRObiotic) has been demonstrated to modulate information processing strongly linked to anxiety and depression and to improve the neuro-endocrine stress response in lab animals – in plain English, this probiotic turned anxious, fearful mice into mellow ones.
In other words, PREbiotic supplementation with Bimuno REDUCED THEIR ANXIETY LEVELS AND OCD THINKING.
Results showed that the supplemented group paid less attention to negative information and more attention to positive information than either a group given another type of prebiotic (fructooligosaccharides, FOS) or a group given a placebo.
Taking a prebiotic supplement may relieve their life-impinging symptoms while also improving their overall physical health – without the adverse effects of pharmaceuticals. The research that led to the development of Bimuno demonstrated only Galacto-oligosaccharides (GOS) to be useful in reducing anxiety levels and OCD thinking in the study’s subjects. The increase of hippocampal BDNF after prebiotic intake is consistent with a probiotic effect, and may have been a direct consequence of elevated gut Bifidobacteria numbers. But in the process of translating complex research into attractive material for general consumption important details and subtleties are often lost. Collectively termed the human microbiota, it is estimated that there are perhaps 10x more microbial than human cells cohabiting our bodies[1]. Scientists have already demonstrated that the gut microbiome is importantly involved in the development of the human immune system, and that abnormalities in microbial diversity are correlated with several inflammatory diseases, as well as colon cancer, diabetes, and obesity [1]. The past few years has seen a significant increase in scientific publications that examine if and how the microbiome may also influence our mood and behavior.
The suggestion that our intestinal bacteria are involved in behavior and mood has been particularly marketable, as it is an appealingly simple explanation for depression, anxiety, eating behavior, and even memory.
There are two primary ways of altering the intestinal microbiota, either with probiotics, which are live microorganisms, or prebiotics which are essentially bacterial food sources that cannot be metabolized by the host organism.
Looking at two very recent studies that report a link between human intestinal microbiota and the brain we can start to get an idea.
The amount of time it took participants to complete that task gave researchers an idea of how much attention volunteers paid to the different types of stimuli.
In general, we experience a significant increase in cortisol levels within the first hour of getting up in the morning, theorized to be a physiological means of preparing for anticipated stress during the day [6]. The majority of other emotional tests showed no significant difference in response between the test groups. These are bold claims, and while they openly acknowledge that their findings are preliminary, the suggestion that prebiotic consumption will effect human behavior is simply not conclusive from the correlations they observe.
Brain activity was monitored during a resting state and while subjects performed tasks that had them identify certain emotions in human faces [7]. In particular they note there were noticeable changes in the periaqueductal gray region of the midbrain, a region of the midbrain that is involved in pain regulation[7]. Dannon both funded part of this research as well as provided the probiotic milk product that this trial tested. Though popular articles may describe some of the particulars and vagaries of the research, they seriously misrepresent the correlations and data by presenting preliminary evidence as something close to proven fact.


There is promising evidence that the microbiome is intimately involved in human health, including brain function and behavior.
For this reason, allopathic medicine that treats candidosis produce results only in the early days, after which the fungus becomes totally immune to that medicine. It is imperative to follow a diet rich in protein and fats and low in carbohydrates (sugars). As we already said, Candida has a very fast capacity to reproduce… as long it has proper food. Therefore, when an antifungal works well against candidosis, may occur dizziness, headaches, skin rashes, diarrhea, excessive gas or fever. Commercialized pasteurized dairy products are never going to equal those homemade obtained from raw and unpasteurized milk. Besides probiotics from foods, probiotics supplements may be taken – they are also very useful because they contain a wide range of lactobacillus species (Bifidobacterium bifidum, Bifidobacterium breve, Bifidobacterium infantis, Bifidobacterium longum, Lactobacillus acidophilus).
Most prebiotics are found in foods high in soluble fiber: flax seeds, leafy greens, leeks, cabbage, garlic, onions, leguminous, but also in cereals (which however are not recommended in the anti candida diet). Do not overdo because sodium bicarbonate is strongly alkaline and damages the acidity of skin. After this is done for 5 minutes rinse your mouth with oil (any oil and preferably cold pressed) and then spit.
Vitamin D is proving to be miraculous for health activating no less than 200 antimicrobial peptides. Probiotics are essential to our health – an unbalanced gut microbiome produces chronic inflammation in the gut and in other parts of the body, leading to all sorts of autoimmune diseases and other serious health problems. He is the co-author of The Probiotics Revolution: The Definitive Guide to Safe, Natural Health Solutions Using Probiotic and Prebiotic Foods and Supplements. They make sure an extended shelf life for the different probiotic supplements, and they do not require refrigeration at all. A supplement like Naturae Vita’s Bioflorathin uses only the highest quality of proven probiotic and prebiotic strains. Anything that wouldn’t exist 50 or so years ago, before our food supply became a completely processed, profit-driven health disaster.
If our gut flora has already become seriously out of balance, we can also benefit from taking high quality probiotics as supplements to populate the necessary array of friendly bacteria in our gut microbiomes. An out of balance (dysbiotic) gut microbiome produces a wide variety of symptoms – including anxiety, depression, and OCD. The people who had taken Bimuno® also had lower levels of cortisol (a stress hormone linked with anxiety and depression) in their morning saliva.
Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers. Unfortunately these losses can result in misleading representations of science, communicating preliminary and correlative data as nearly proven fact. Scientists have become increasingly interested in studying the human microbiota because these organisms contribute a huge amount of genetic material to the overall human genome.
The idea being that the microbial cultures in our guts are interacting with our nervous systems through the molecules and proteins they secrete. If there is a link between the intestinal microbiota and the brain then pre and probiotics present exciting avenues for psychological therapies.
By examining their methods, conclusions, the various interest groups involved, and the accompanying media coverage we can get a sense of both what is known, where the research is headed, and the aspects that have been skewed in the media. Immediately after waking on the mornings of the first and final days of the trial, participants self-collected samples of saliva. For example, if patients were able to count the number of stars in the same location as the positive stimulus more quickly that those in the location of the neutral stimulus, this indicated that they were more attentive to positive stimuli. This correlation between prebiotic consumption and lower cortisol levels may demonstrate a connection between the gut microbiome and the human nervous system. Such a situation is common across industry-funded research, and underlines the persistent tension between financial and academic interests threatening scientific objectivity. Kristen Tillisch an associate professor of medicine at UCLA in 2013, the study involved 36 women given either a milk product supplemented with probiotics, milk without probiotics, or no intervention over the course of 4 weeks. Forbes magazine wrote that this research showed how “brains of people ingesting a probiotic for four weeks had less activity in brain areas associated with excessive anxiety”[9]. But there is equally clear evidence that media coverage walks far ahead of the scientific work it intends to report, too often condensing preliminary, correlative and complex data into pat headlines. Depression, anxiety come from the gut: Surprising new research suggests ‘prebiotics’ can help. As you saw above, there are a whole series of diseases that were associated with candidiasis, however not everyone who suffer from candidiasis also has cancer.
It cooperates with T cells and activates no less than 200 antimicrobial peptides – immune system components that are designed to fight harmful organisms entered the body. After the sterilization process, commercialized yogurts contain more DEAD probiotics, instead of containing live bacteria (active). Therefore it can be used successfully in treating various mycosis (fungus) that occur on the exterior.
People with intoxications will spit a whitish liquid (like mayonnaise) that is NOT allowed to be swallowed because it is TOXIC. In this way will help restore the beneficial flora, but you will eliminate harmful organisms. If your gut microbiome is lacking in probiotics, pathogenic bacteria can move in opportunistically and take over. They are manufactured properly to ensure that no damage is done to the living organisms and great care is taken in packaging and storage to guarantee that the large amount of bacterial colonies present in the supplement remain fully alive and intact so consumers get optimum benefits from their supplement. Prebiotic evaluation of a novel galactooligosaccharide mixture produced by the enzymatic activity ofBifidobacterium bifidum NCIMB 41171, in healthy humans: a randomized, double-blind, crossover, placebo-controlled intervention study.
Modulation of the fecal microflora profile and immune function by a novel trans-galactooligosaccharide mixture (B-GOS) in healthy elderly volunteers.
PYY) or other mediators, such as the immune system resulting from direct oligosaccharide-gut interactions, cannot be ruled out.
The genomes of our microbiota, and the way they interact with the human host, are collectively termed the microbiome. Altogether, the accumulating body of scientific literature has provided early glimpses at potential links between our gut bacteria and conditions such as anxiety, depression, schizophrenia, and autism [3].
Subjects were then given a series of emotional processing tasks in which attention to positive versus negative stimuli was measured. Researchers observed that those given prebiotics tended to be less attentive to negative stimuli [5].
The researchers suggest that this correlation may point to prebiotics having an anti-anxiety affect that is similar to existing pharmaceuticals. Fecal samples from the volunteers were analyzed for Bifidobacterium lactis, which was the active probiotic in the supplement, such that potential control subjects were screened to be B.
While the general idea is accurate, making the connection to anxiety is still a stretch and grossly oversimplifies the research. However, fortunately there are some yogurt brands that offer quality, NEVER as good as those you can make at home. The elevation of NMDAR subunits after prebiotics is intuitive given their reduction in the brains of germ-free animals.
There are many examples of media distorting or overselling science, but right now there is probably no better example than much of the coverage of research on the human microbiome and how its manipulation might impact human mental health.
The fundamental hypothesis that is driving, and increasingly validated by, human microbiome research is that all of this microbial activity adds up to a significant impact on human physiology.  More and more we are developing an understanding of what kinds of microbes are living where, and how they are intimately involved in human health and disease. The likely end result is the degradation of public trust in the integrity and validity of scientific research. It is important to eat healthy during this time and let your body to perform its natural detoxification processes without disrupting it with drugs to lower fever, or antibiotics. I would have no less requirements of proof of scientific results for reportedly natural stuff that I would for other stuff. Furthermore, the strong correlation between Bifidobacteria numbers and cortical NR1 levels presented in this report, further supports a link between the microbiota and central glutamate neurotransmission. Mechanistic investigations beyond the scope of the present study, are now required to ascertain the systems underlying the observed changes, and will also reveal if vagal nerve modulation is involved. Moreover, behavioural analysis in rats will ascertain if the changes in BDNF after prebiotics impart an anxiolytic action, or that increased NMDAR subunits translate to improved cognitive performance. Importantly, our study has provided sufficient cause to warrant further exploration into the utility of prebiotics in therapies of neuropsychiatric illness and which, by virtue of their ability to proliferate gut bacteria and stimulate neuroendocrine (and other) responses, may even prove to be more potent than probiotics.



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