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For over a decade, I have recommended a trial of probiotics to virtually all of my patients.
Probiotics are a vast group of living microbial organisms comprising normal gastrointestinal flora. Examples of probiotics include bacterial species  Lactobacillus and Bifidobacterium, as well as the Saccharomyces yeasts. Prebiotics are nondigestible fibers and complex sugars that promote the growth and metabolic activity of the beneficial bacteria, primarily the Bifidobacterium, in the colon.
Prebiotics were not defined until 1995.  One example of a prebiotic is inulin, found in Jerusalem artichokes and asparagus stems. Fermented milk products such as yogurt and kefir are considered synbiotic because they contain both the live probiotic bacteria and the prebiotic fuel working synergistically.
For thousands of years, the food we ate was unrefrigerated, unpasteurized, and unprocessed. The intestine is our first line of defense against harmful pathogens, chemicals, and preservatives that we do not want in our bodies. One leading scientific hypothesis proposes that dysbiosis allows tight junctions to loosen up, resulting in leaky gut syndrome or intestinal permeability.
To maximize their effectiveness, probiotics must remain stable in the acidity of the stomach and the alkalinity of the duodenum. If my client is taking probiotics to “promote good gut health,” I support exclusive use of food sources of probiotics. Probiotic supplements are formulated with a special coating to withstand stomach acid and bile before dissolving in the small intestine. The past decade has seen an increase in the number of scientific studies on the effectiveness of probiotic supplements.
It is challenging to provide detailed recommendations on which probiotic supplement to take and what dosage, due to variability in strength and viability.
The International Scientific Association for Probiotics and Prebiotics (ISAPP), in The P’s and Q’s of Probiotics: A Consumer Guide for Making Smart Choices, recommends looking at these four criteria prior to choosing a probiotic.
Probiotic Strain–  Try to match the particular strain with published scientific research.
Do not take the probiotic with a hot beverage or cereal, as the heat might destroy some of the good bacteria. If taking prescription antibiotics, wait two hours before taking the probiotic so they do not cancel each other out. Occasionally, I will have a patient experience more severe symptoms when they first begin taking probiotic supplements. If you experience the Herx reaction, it is best to cut back on the dosage, while continuing to take probiotics until the toxins are eliminated from the body. Once the harmful bacteria have been eliminated, it is time for the probiotics to do their job. This list ONLY includes probiotics which are manufactured in accordance with cGMP guidelines. If a probiotic was NOT manufactured in clean, regulated conditions, as per cGMP guidelines then in all likelihood it will not only be ineffective but it could be POTENTIALLY HAZARDOUS! Potency – WAY too many companies leave their probiotics sitting around gathering dust, over 50% of the brands that we tested had ZERO live cultures left!
CFU (Colony-Forming Units) – this is the total count of all of the bacteria in the probiotic, VERY important because probiotics are ONLY EFFECTIVE IN ADEQUATE AMOUNTS. Strains – total number of different types of bacteria in each probiotic, varies greatly and, along with strain diversity, affects the types and levels of benefits that you will notice.
Strain Purity – a combination of the effective concentration of the strains within the probiotic and the functional quality of the active cultures (the ability of the bacteria to perform its specific job). From Lactobacillus acidophilus to DE111TM Bacillus Subtillis, BlueBiotics is a veritable list of the most researched and proven probiotic bacteria known to science.


Contains two types of well-documented probiotics, Lactobacillus acidophilus and Bifidobacterium animalis. Although more for individuals who are looking for their probiotic to address a very specific health issue, TruBiotics does its job very well.
I would like to find out the other probiotic tested and the percentage of live bacteria or potency at test date. Author & Researcher Julia Roe has been with us for over six years, contributing more to CHR than any other individual researcher. There was not much published literature, but there were a lot of theories about how the body’s bacterial population influenced overall health.
By the time my book was nearing completion in 2012, I had to re-write the whole chapter because of all the new scientific studies!
Put simply, probiotics are good bacteria that are supposed to live in your intestinal tract. In 1965, researchers coined the term “probiotics,” though the concept and use of beneficial bacteria to promote health had been around since the early 1900s. They provide fuel for the probiotics already living in the intestine, favoring the good bacteria over the harmful ones.
Fructooligosaccharides (FOS), which occur naturally in garlic, onions, green bananas, zucchini, watermelon, and peaches, are another type of prebiotic. However, it is my experience that those who suffer from IBS-D (diarrhea predominant) or who are FODMAP-sensitive do not tolerate prebiotics; it exacerbates their diarrhea. In order to fight these invaders, the cells in the small intestine tightly line up next to each other, forming an impermeable barrier.  Probiotics assist the cells in maintaining these tight junctions. Openings created between the cells may permit proteins or toxins cross the intestinal barrier. Further down the GI tract, they must adhere to the surface of the small intestine and effectively populate the colon.
Yogurt is the most common and familiar form of probiotic, which contains primarily Bifidobacterium and Lactobacillus species.
However, if a patient is actively experiencing gastrointestinal symptoms from a known disease or disorder, I typically recommend they add an over-the-counter probiotic supplement to their daily regimen. Once the probiotics are released, they can adhere to the intestinal wall and support immune system function.
However, one difficulty in creating a clinical trial is the wide variety of yeasts and bacteria species available. When independent companies test products, they find wide variability in the quantity and potency of live bacteria in each capsule. I do not recommend one particular brand over another, primarily because information changes quickly, and specific probiotics may be better-suited for a particular medical condition.
Scientific studies have determined health benefits from 50 million to over 1 trillion colony forming units (CFUs) per day. Strain, quantity of CFUs, serving size, health benefits, proper storage conditions, expiration date, and additional corporate contact information should all be included.
It may take two to four weeks for those symptoms to subside while the good bacteria insert themselves into the intestine. Charcoal tablets taken about two hours after the probiotics can help bind and remove the toxins.
Doctors may have been prescribing them for decades, but only recently have people started including these extraordinary supplements in their daily diets. Potency is the % of live cultures we discovered upon testing the brand, you’d be surprised at how many companies store their probiotics for way too long.
This is the only full-spectrum probiotic supplement on the market, as it contains strains which are typically not available to the general public (Bacillus Subtillis and Bacillus coagulans). If you aren’t looking for any of the other health benefits of probiotics, this should be your weapon of choice. Align contains only one probiotic culture, Bifidobacterium Infantis, which is both highly studied and effective.


However, our lab results weren’t as positive as with BlueBiotics and we found that the amounts of actual live and active cultures were effectively less than our top pick.
Again, the test results were not overwhelmingly positive – however they still measured well inside the advised levels of effectiveness. In order to post comments, please make sure JavaScript and Cookies are enabled, and reload the page.
Julia has dedicated the past 17 years of her life to professional coverage of the constantly evolving modern medical and health world. Of all the strategies I discuss with clients, adding probiotics has resulted in the most significant decrease in chronic diarrhea. Beyond the benefits of carbohydrate, protein, fat, and calcium contained in the yogurt itself, it contains active cultures of L. Once the foreign invaders are inside, antibodies are created as the immune system is activated. However, fermented dairy beverages such as kefir actually contain a higher concentration of live cultures. In scientific studies, many probiotics are used individually or in combination with other bacteria or yeasts.
The following table presents different conditions and the species of probiotic which has been scientifically studied and proven effective for that particular disease or disorder. One exception: you may continue to take a yeast probiotic (such as FloraStor®), with your antibiotic. It occurs when the bad bacteria are dying off and the body is unable to release the toxins quickly enough. Those who have started regularly taking probiotics have reported many improvements in their overall health.
The CFU count alone is remarkable enough, leaving most comparable spectrums in the dust… HOWEVER even more surprisingly our tests showed that a whopping 98% of the probiotic colonies in BlueBiotics were still alive, making this BY FAR the most effective probiotic supplement that we have ever reviewed. This particular strain has been shown to be very effective in addressing a variety of digestive tract issues.
However, these probiotics have a very high, diverse strain count which makes this product ideal for those who do not have any pressing health issues, but are looking for a solid general supplement for well-being.
If the two strains in Trubiotics are the ones that you are looking for, TruBiotics is a fair place to begin your foray into probiotic supplements. While this has prevented many types of dangerous illnesses, it has resulted in fewer beneficial bacteria living in our gut as well.
Many autoimmune and gastrointestinal disorders have been linked to leaky gut syndrome; these include Crohn’s disease, celiac disease, Type 1 diabetes, psoriasis, and eczema. In today’s marketplace, you can also find probiotics in soup, cheese, energy bars, even cereal.
Studies have shown that some species are more effective in treating a particular disorder or disease. In the short-term—days to a few weeks—these toxins can exacerbate the symptoms being treated and cause more gas, bloating, or diarrhea. Also, because of the diverse pool of strains in BlueBiotics, users have reported a wide variety of benefits from weight loss, to increased energy, improved digestive health and cognitive function. Many of our staff switched to these probiotics, as well as myself and my family. This product is ideal for those who do not have any pressing health issues, but are looking for a general supplement for well-being. They may also create their own flu-like symptoms including headache, joint and muscle pain, body aches, sore throat, general malaise, sweating, chills, or nausea.
While well-founded, we at CHR would still recommend BlueBiotics for antibiotic-related health issues.



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