Beneficial effects of probiotic microorganisms. a review,reviews of garden of life raw probiotics,raw probiotics colon care side effects 8mg,forever active probiotic 30 capsules bottle - Test Out

Product Description 4 Targeted Probiotic Strains (including Lactobacillus and Bifidobacterium) to effectively counter the indiscriminate effects of today's broad spectrum antibiotics and other lifestyle choices that can deplete our microbiome. Our digestive systems are home to hundreds of different bacterial species that keep our intestinal linings healthy, break down food, and regulate our immune response. Evidence suggests that by controlling the immune response, supplemental probiotics can help prevent and treat diarrhea and decrease inflammation caused by diet and stress — whether from life or exercise.
But can probiotics also reduce GI damage, symptoms, and illness caused by intense exercise? Is your belly in balance or do you suffer from CPBBS (caca-poopy-blocked-up-bowel syndrome)? Okay so maybe CPBBS isn’t exactly an official term for GI disturbances, but more than likely you or someone you know suffers from occasional “plumbing problems” ranging from gas and bloating to nausea, stomach cramps, constipation or diarrhea. Not surprisingly, diet and lifestyle play a key role in keeping our intestines running smoothly.
Exercise shunts blood to the muscles, away from the GI tract, and raises our core temperature.
And before you know it, you’re sick with a respiratory infection or some other illness (1). We all host similar species of beneficial bacteria, but how much and which type can vary greatly, depending on the factors above, and they can also vary over time (1, 2, 3). Most likely you’ve heard that after taking antibiotics you need to repopulate your intestines with good bacteria to keep from getting sick again and put balance back into your intestinal ecosystem. Generally, we don’t want inflammation in the body because it can cause our proteins to lose function and can damage the lipids (aka fats) in our cell membranes, creating free radicals. While manufacturers of popular yogurts and probiotic drinks may try to persuade you that their product holds the key to your intestinal health, not all probiotics are created equal.
For example, some strains like Saccharomyces boulardii may help with diarrhea, while strains of Lactobillus and Bifidobacterium have been shown to have beneficial effects on tight junctions and intestinal barrier function (5).
Sadly, there are a good many other species found in foods that simply don’t survive digestion and won’t make it intact to your GI tract. While taking probiotics is an area that is being researched for ailments ranging from irritable bowel and ulcerative colitis to allergies and diarrhea, there is little research in the context of sports and exercise. This week’s research review explored the effects of probiotic supplementation on intestinal permeability in male endurance athletes.
Does probiotic supplementation affect markers of oxidation and inflammation in plasma, before and after intense exercise?
This study used a randomized, double-blinded, placebo-controlled design, which means that the subjects were randomly assigned to either the experimental group or to the control group The experimental group took a probiotic supplement; the controls took a placebo supplement. Because the study was double-blinded neither the researchers nor the subjects knew who was receiving what. At baseline and at the end of the 14 week study all subjects completed 90 minutes of intense exercise.
While it wasn’t clear why 3.5 months (14 weeks) was chosen as the treatment time, most likely it was due to study feasibility along with the fact that 14 weeks should be ample time for the probiotics to have an effect. At baseline and at the end of the study, the subjects’ poop and blood was collected and tested. The 23 men were randomized into blocks of 6, with 11 subjects in the probiotic group and 12 in the placebo group.
In plain English: ranking is a relationship between a set of data (in this case VO2max) that “ranks” values as either higher than, lower than or equal to the second. On the morning of the first exercise test, everyone received the same pretty substantial breakfast of just over 1000 calories, 3 hours beforehand. Before the first triple step test the men completed a 7-day food diary that was then analyzed. The subjects were then given copies of their 7-day food diary records and asked to duplicate this diet exactly for the 7 days leading up to the second triple step test at the end of the study. Both groups received sachets, which either contained probiotics (experimental group) or a placebo composed of a cornstarch maltodextrin matrix (control group). The strains contained in the sachets of the experimental group included those you would find on most common priobiotic supplements including Bifidobacterium bifidum W23 and Lactobacillus acidophilus W22.
Both groups were instructed to take 2 sachets for a total of 4 grams per day, which was equivalent to 1010 CFU per day. For 3 days before each exercise test, the subjects were told not to perform physical training. During the test, an electrocardiogram, oxygen uptake, carbon dioxide, breathing rate and heart rate were recorded. The entire test lasted between 80 to 90 minutes, depending on how long it took the subjects to reach exhaustion during each of the 3 steps. The subjects also had blood drawn after an overnight fast so that standard blood chemistry values could be determined. Researchers collected several different types of measures, to get a broad picture of what was happening to the subjects.
Measurement of VO2max, VO2max related to body weight, maximum performance and performance related to body weight were assessed in each group in each of the tests. This is another measure related to the integrity of the GI barrier, which estimates protein leakage into the intestinal tract.
This is a measure of protein oxidation and when elevated can result in a loss of enzyme and protein structure and function.
This represents the amount of total lipid peroxides, an indicator of lipid peroxidation throughout the body. This is a pro-inflammatory cytokine (signaling molecule) and central mediator of systemic inflammatory response. This is a cytokine that originates in skeletal muscle and is known to increase with strenuous exercise. How does 14 weeks of probiotic supplementation affect surrogate markers of intestinal barrier function, including intestinal permeability? How does probiotic supplementation and a given exercise protocol affect markers of inflammation and oxidative stress? What they found: Probiotic supplementation improves intestinal barrier function and reduces inflammation in trained male endurance athletes.
No significant differences between probiotic supplementation or placebo for the performance measures taken during the exercise test. No differences between groups at baseline, but both groups had concentrations that were 15-25% above normal.
Measured MDA values were within normal range and there were no differences between groups at any point either with exercise or with treatment. Measured TOS values were above normal at all time points but there were no differences between groups as a result of exercise or intervention. IL-6 levels were within normal range pre-exercise in both groups at baseline and at 14 weeks. Intense exercise seems to take its toll on the immune system by compromising the integrity of the intestinal barrier leading to “leaks” and increased permeability.


In the case of your intestines, leaks mean that toxins and other undesirables make their way into your bloodstream. In this study, after 14 weeks of supplementation with probiotics, zonulin concentrations – a modulator of intestinal barrier function – decreased from slightly above normal to normal range. This means the probiotics worked to “seal the leaks” by affecting the expression of the signaling pathway that increases intestinal resistance. Supplementation also decreased protein oxidation and the chronic inflammatory marker TNF-?.
Lastly, the exercise protocol did not induce oxidative stress but increased concentrations of the inflammatory cytokine IL-6. This means that probiotics don’t have an effect on the normal increase in this signaling molecule as a result of strenuous exercise. For anyone who exercises intensely, the results of this study seem to point to a role (albeit modest) for probiotics as part of a daily routine. Evidence supports including fermented foods or probiotic supplements into your routine for maintaining a healthy digestive balance. If you prefer to stick to foods, fermented foods like sauerkraut, kimchi, sourdough bread, and soft cheese like Gouda are all good sources of various strains of lactobacillus bacteria. In it you’ll learn the best eating, exercise, and lifestyle strategies — unique and personal — for you.
In vitro lab testing shows that less than 4% of the probiotics in most chewables, powders, and capsules survive your child's stomach acids to deliver any benefit. 80% of your immune system is in your gut, and when probiotics (the good guys) are abundant in your body, it's harder for the bad guys to settle in. From our modern dietary choices to our daily hygiene regimens, many things can affect the balance of bacteria critical for healthy digestion and immunity.
This very tiny pearl is the smallest on the market and is easy to swallow for most children ages 4 and up. Avoiding the synthetic and sugar-loaded ingredients you know are not beneficial for your child can be quite a challenge!
Less blood to internal organs and an increased internal temperature can disrupt the intestinal lining, setting off the inflammatory response. This microbial ecosystem is so complex that it is considered to be a virtual organ system essential to the maintenance of our health! The good bacteria, aka probiotics, interact with the cells of our intestinal lining and affect our immune cells. But really, tight junctions are barriers that seal the space between the tissues lining our internal surfaces (epithelial cells).
Undigested gluten fragments seep into the underlying tissue, setting off an immune response.
Interestingly, certain strains of probiotics have also been shown to play a role in the development of obesity and type 2 diabetes (2).
But wouldn’t you like to know if adding a daily dose of good bugs to your routine would make you an even healthier athlete?
Probiotic supplementation affects markers of intestinal barrier, oxidation, and inflammation in trained men; a randomized, double-blinded, placebo-controlled trial. Fortunately, in double-blinded studies the treatments are usually coded so that at the end of the study the researchers can find out which subjects belonged to which group. While there is no science behind it, anecdotal evidence seems to suggest that probiotics can have an effect in as little as a few days.
The researchers wanted to ensure that there was a balanced distribution of VO2max between the groups so they stratified the participants using rank statistics. It was high carb (60%), moderate fat (27%) and moderate protein (13%) – a  good breakfast for a pre-workout meal – and while high in calories, the subjects needed the fuel for the intense exercise test that was to follow.
First they had to undergo eligibility testing by completing an incremental step test to exhaustion on a cycle ergometer.
They had 15 minutes between intervals and were allowed to remove their face mask to drink some water.
Most of the indicators focused on measuring inflammation and GI health (for instance, the integrity of the intestinal barrier).
Lipid peroxidation sets off a chain reaction that can result in tissue damage and can lead to the initiation of disease.
Fecal concentrations were normal at baseline and after the 14 week intervention in both groups. However, in both groups IL-6 increased significantly by similar amounts after exercise at baseline and at 14 weeks. If you decide to try a supplement, choose one that contains a variety of strains and at least 1 billion or more active cells.
Fermented soy foods like miso and tempeh also include over 160 different bacteria strains (5). With superior patented technology, 60% of PRO-Kids probiotics will reach deep into your child's intestinal tract where they are needed most. PRO-Kids helps restore your child's beneficial bacteria for optimal digestive and immune health. With proper probiotic supplementation, you can help repopulate your child's gut, promote full nutrient absorption and reactivate their natural defenses, giving your child a solid foundation for a lifetime of health.
PRO-Kids pearls are most effective when swallowed rather than chewed (though they still taste great if chewed!). You can rest assured because PRO-Kids is sugar free (sweetened with stevia) and has ZERO artificial colors, flavors, or sweeteners.
But high-performance athletes, especially endurance athletes, suffer a lot of GI complaints.
When the good bugs outnumber the “bad” bugs, or toxins, the result is a smoothly functioning digestive system and less overall inflammation. They “glue” intestinal cells together and regulate the flow of large molecules between the bloodstream and the inside of the intestine (the intestinal lumen). The expression of these proteins is influenced by dietary components like polyphenols—the antioxidant compounds found in foods like legumes, berries and chocolate – and it is also influenced by a number of probiotic strains.
In statistics it makes it easier to evaluate complex information without relying on a particular characteristic. The actual exercise test in the experiment used a similar protocol, but repeated the incremental test twice more for a total of three step tests to voluntary exhaustion. After the intervention a post-exercise increase was still observed, but it wasn’t significant. Including women as well as men, using different exercise protocols and evaluating more strains of probiotics – namely the common ones that you and I buy – would be extremely helpful.
3 Billion Colony Forming Units per BIO-tract pearl - which is equivalent to 45 Billion CFU (colony forming units) of standard probiotic capsules!
PRO-Kids pearls are most effective when swallowed rather than chewed, though still taste great if chewed!
Naturally Derived Prebiotic included in each pearl to help feed the probiotic for increased potency and effectiveness.


Prebiotics are basically fibers that encourage the growth of beneficial bacteria throughout your colon. With the patented LiveBac manufacturing process, we offer a guaranteed shelf life of 18 months from the date of manufacture, unlike most probiotics that don't provide a date of any kind because their organisms die so quickly after being manufactured. Because with time-release delivery, the full benefits are being delivered deep inside your child's gut hour by hour. Made in the USA. Our probiotics are homegrown with care in Washington state then tableted in Colorado. The Science Behind the SuperiorityGas, bloating, irregularity, weakened immune system, malabsorption of nutrients, yeast growth, and other health and digestive problems affect many of us on a regular basis.
Probiotics help restore the beneficial gut bacteria that may have been depleted as a result of poor diet, the overuse of antibiotics, food poisoning, or environmental toxins and promote overall health and well-being. However, studies show that without protection most probiotics entering the stomach won't survive to reach optimal sites within the gastrointestinal tract. Powders, liquids, capsules, and even cultured dairy products retain only 4% of these sensitive organisms during passage through the stomach's harsh environment. The good news: with the patented BIO-tract protection and time-release delivery, we have increased this number to a remarkable 60%.
The BIO-tract Difference: Probiotic Survival Past Stomach AcidsWhen the tablet is moistened by gastric fluids, a gel matrix forms that creates a protective layer, shielding beneficial organisms from stomach acids and directing them to release later in their journey. Once inside the gastrointestinal tract, probiotics begin to release at consistent levels from the tablet core, delivering a potent percentage of our living organisms throughout the day and throughout your gut, traveling deep into your intestinal tract where they are needed most. Finally, you can experience the full benefits that probiotics have to offer! This is the only controlled-release delivery available for probiotics on the market today and is patented in 31 countries (US Patent 8,007,777 and 7,150,623). Enteric Coated and Veggie Capsules Most probiotic supplements are in veggie capsules which offer no protection from a harsh stomach environment, meaning that many of the beneficial organisms do not survive long enough to deliver any benefit.
Enteric coated probiotic capsules offer some protection from stomach acids with a few drawbacks. Most enteric coatings are made of a synthetic chemical that the capsule is then dipped into. In addition to unwanted added chemicals, the capsule contains air and the coating contains moisture that is detrimental to the probiotic organisms. You see, freeze-dried probiotic powder is ‘hygroscopic,’ meaning that it seeks out moisture. The beneficial flora will start wicking the moisture away from the air and the coating, which starts killing the living probiotics inside. Essentially, both veggie capsules and enteric coated capsules cause the living organisms inside to self-destruct, leading to a far less potent product. Instead of a coating or a capsule, we tablet our formulas using a patented manufacturing process called LiveBac and a patented delivery method called BIO-tract, which provide much better protection for the beneficial flora while on the shelf (as there is minimal air and moisture) and as the tablet travels through the harsh environment of your stomach acids. Simply put, this leads to a much more effective probiotic and exponentially greater health benefits for you.
Furthermore, BIO-tract ensures that the active organisms are released slowly over an 8-10 hour period while making the journey through the intestinal tract, successfully bypassing your stomach acids so that they can colonize in your small and large intestine, where you actually need them.
PRO-Kids pearls are most effective when swallowed rather than chewed (though they still taste great if chewed!)GIVE YOUR CHILD THE FOUNDATION OF A STRONG IMMUNE SYSTEM.
From our modern dietary choices to our daily hygiene regimens, there are many things that can affect the balance of bacteria critical for healthy digestion and immunity. With proper probiotic supplementation, you can help repopulate your child's gut, promote full nutrient absorption and reactivate their natural defenses, giving your child a solid foundation for a lifetime of health.KEEP YOUR CHILD HEALTHY. Customers Who Bought This Item Also BoughtPage 1 of 1 Start overPage 1 of 1 This shopping feature will continue to load items.
In order to navigate out of this carousel please use your heading shortcut key to navigate to the next or previous heading. I have been taking them for about a month but I was extremely cautious when it came time to pick one for my son who is 4 with severe flare ups of eczema.
We have been using these for our children for months now and the results were almost instantaneous. My 7 year old has struggled with IBS for a few years now and it was only compounded by a lengthy stay in the hospital for pneumonia, where she was pumped full of about 3 different kinds of antibiotics. I tried several different kinds of probiotics and the tummy aches and diarrhea still persisted.UNTIL, I was searching amazon, reading all of the reviews for as many different probiotics as I could find for kids. I wanted something natural that didn't have added sugar and dyes and things that would simply worsen the condition. I read the reviews for this Pro-Kids probiotics and there were a couple from people who claimed they had tested the probiotics for live good bacteria. I was a little skeptical, thinking maybe they were paid to say this or something like that. But, I decided for $20, it was worth a shot.I bought a bottle and tried it for the first month. We hadn't done this in years!!!!I am so thankful to have stumbled upon this company and we have since ordered the Pro-15, with great results for our adults as well. We are very pleased with the Hyoerbiotics line of probiotics and would definitely recommend them to anyone! Doctors have prescribed nasal decongestant recently and it only sometimes helped and I didn't want to give it everyday.
He complained about tummy aches too (most likely due to bloating caused by poor digestion of certain fibers). I didn't believe in supplements or alternative medicine, until not long ago I had to start doing some research about how to boost my immune system for myself as I got sick way too often.
I chose this brand for the kids and myself because it might be more effective due to the slow release design, presence of B.
Infantis (good for bloating), and prebiotics (food for probiotics).Shortly after taking this, my son's nasal congestion has disappeared (except a couple of night when he had a mild cold)!
I noticed that because I have been sleeping through the night without hearing him struggling with breathing and having to get up to give him nasal decongestant.
He is recovering from a stomach flu (bad one as he had a high fever) but the whole illness only lasted for 1.5 days! I would not claim this would keep you illness-free but would definitely shorten the duration for certain illnesses.My son is an anxious and sensitive boy and had trouble swallowing in the beginning because it's an all new experience.
Instead I suggested him to bite it once or twice until it's small enough for him to swallow with water.
Gibbs 2.0 out of 5 starsMy kids hate the taste (and I don't disagree) My kids complained about taking these after happily taking several other brands.



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Comments to “Beneficial effects of probiotic microorganisms. a review”

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