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London, January 12: Allergy medications may indeed make a subsequent allergic attack even stronger, according to a study. Pal Johansen at the University of Zurich, Switzerland, conducted a study on mice to determine the long-term effects of antihistamines — medicines known to offer a great way to fight off an allergic attack — on the immune system. He and his colleagues injected 50 mice with bee venom, a substance to which almost all organisms develop an allergy upon exposure. 100 micrograms of the antihistamine Clemastine just before they were given venom, and 100 micrograms on each of the two days afterwards.
After six weeks, the researchers injected the mice with another dosage of bee venom, and monitored the allergic reactions. The findings, published in Clinical and Experimental Allergy, suggest that the mice on allergy medication had not developed tolerance to the allergen. In the second part of their research, the researchers desensitised the mice to the bee venom by using immunotherapy, a process of introducing tiny amounts of an allergenic substance to an allergic individual, slowly helping the immune system to tolerate the substance.
They found that mice that had originally been administered the allergy medication responded more poorly to the immunotherpay than the other mice, when sensitised with venom. However, Cezmi Akdis, director of the Swiss Institute of Allergy and Asthma Research in Davos, feels that more research is required on the subject because there is no evidence that rodents and people metabolise Clemastine at different rates. He points out that only two studies have so far suggested that antihistamines help immunotherapy, and that the current study is the first to contradict them. Number of factors ranging from common skin rashes to erythema nodosum or psoriasis can cause red itchy bumps on the skin. It can be due to allergic reactions, hives, chicken pox, dermatitis, eczema, psoriasis and folliculitis. Allergic reactions can happen by the intake of medicine or exposure to polluted atmosphere or due to virus infection.
Chicken pox is the disease caused by virus which spreads red small sized itchy bumps on the skin. People who are overly exposed to environmental poison like oak, ivy and sumac would get allergic rash with itchy bumps. It would appear as tiny red spots initially on the face or scalp which further proceeds as dark red bumps or lesions on the body. Simple allergic drugs like Allegra or Zyntec are available over the counter for getting relief from itching and inflammation. Respiratory depression is a pattern of regular respirations with a rate of less than 12 breaths a minute.
Anaphylactic shock is an acute dramatic reaction characterized by respiratory depression, angio – oedema, cardiovascular collapse, vomiting and urticaria. Dizziness is a sensation of imbalance, associated with weakness, confusion , blurred or double vision.
Blood pressure relates to the force exerted on the blood vessels and is affected by the cardiac output, peripheral vascular resistance and blood volume. Oral candidiasis is a mild superficial fungal infection caused by the candida species in the mouth. Decreased salivation, or dry mouth, involves the decreased production of saliva resulting from mouth breathing.
Drowsiness or sedation is a decreased level of consciousness follows after the use of medication that depresses the CNS.


Photophobia is an abnormal sensitivity to light results from ocular dilation and reduction in aqueous humour drainage.
Angogenital candidiasis is a mild fungal infection caused by the candida species in the vaginal, anal or penile areas. Vomiting is the expulsion of the gastric contents by the mouth as a result of coordinated contraction of abdominal muscles and reverse oesophagal peristalsis. Blistering is a small thin walled raised vesicle containing clear, serous, purulent or bloody fluid.
Postural hypotension is an abnormally low bp that occurs when an individual takes a standing position.
I'm currently doing my PhD at the University of Auckland in the field of cancer biology and bioinformatics. In a study1 published today, scientists looked at offense and defense among Vibrionaceae, a family of oceanic bacteria that contains the bug that causes cholera. What they found suggests that some bacteria live in genetically similar clusters that cooperate among themselves while battling against outsiders. Previously, microbiologists thought that antibiotics would be deployed shotgun style, but this dog-eat-dog, go-it-alone view of the microbial world is undermined by the new study.
Instead, the situation is starting to look more like Montagues and Capulets, or Jets and Sharks, or Hatfields and McCoys. Some oceanic bacteria live free-floating, solitary lives, but many colonize organic particles, or the skin and gut of ocean animals. To explore the relationship among related strains of bacteria that are genetically different, Polz and colleagues grew pairs of Vibrio side by side. Furthermore, up to 5 percent the 185 strains were super-killers — bacterial thugs that could stifle at least 25 percent of other strains. Instead, these genes kill bugs that are, in genetic terms, more distant — the strangers in their midst.
The battlin’ bacteria remind us of soldier ants, which protect the colony in return for housing, food and the hope that their queen will pass along their genes.
The large soldier ant is charged with protecting the colony — with awesome mandibles that function rather like the antibiotics seen in the Vibrio bacteria.
In other words, some bacteria do certain jobs while others benefit; eventually, both jobs and benefits balance out and are maintained over the course of evolution. And so this revolutionary view of gang warfare and bacterial specialization is clearly something we need to check out.
They found that mice given antihistamines reacted more violently to the second venom injection. We think they were also keeping the immune system from getting used to that dosage,” Nature magazine quoted Johansen as saying.
It is difficult to tell what causes such skin inflammation and infection and why it affects only certain people.
Hives can cause red bumps which spread rapidly on the skin and this condition is caused due to allergic particles.
This infection will appear as small red spots on the skin and it begins on the scalp and goes down till your legs. Alopecia, boils, erythema nodosum, Kawasaki disease, abscess and phlebitis can also cause this problem.


On continuous scratching you are increasing inflammation and the area becomes irritated and causes repeated lesions on the skin. For intense form of rashes he may inject steroid directly on the skin to control irritation. Adverse drug reactions are unwanted reactions and are often seen if higher or inappropriate doses of medicines are taken. In this case the reason is known and the conditions can be reversed by reducing the dose or switching over to another medicine. Raised blood pressure is referred to as hypertension and in this case the arterial walls thicken , become less elastic and resistant to blood flow.
These bacteria are found in the normal flora of the mouth and when the drug alters the balance of this flora it leads to infection and can result in blue – white patches on the tongue, mouth and pharynx. The medication tends to produce this by stimulating the vomiting centers in the medulla oblongata or by irritating the GI tract.
It is generally characterized by a rise in the normal body temperature and affects largely the homeostasis of the body. Bacteria attacked strangers, but not close relatives, which carried genetic protection from the antibiotic. Once a microbe has an antibiotic gene, he says, “We thought its ecological effects would be most pronounced if it killed its closest relatives, because they share resources. Genes transferred horizontally can render difficult pathogens even more resistant to antibiotics. There are variety of treatment options available for itchy bumps and rashes but every one of them is good enough to address the symptoms and not the underlying disease. Fever, nausea, vomiting and constipation problems may accompany the disease if it is caused due to allergic reaction or poison. It takes time for it to appear on the skin and similarly you should understand that it takes sufficient time for getting healed. In case of infectious rashes antibiotics are given orally and in the form of topical creams.
When there is a reduced cerebral perfusion to activate the neurons of the respiratory center or when there is a change in the levels of arterial carbon dioxide and they trigger the chemoreceptors, or when there is a reduced effectiveness in changing the levels of carbon dioxide by the respiratory neurone there can be respiratory depression. In this case the body shows reactions physically – as in rashes etc, upon exposure to sunlight. And bacteria are the chemists of the natural world, using chemistry for offense, defense and communication.
Fungal skin infection is divided into two categories depending on the organism responsible for it.
They areDermatophyte infections are caused due to dermatophyte, a type of fungi that causes infection in the nails, skin and hair.
The most common diseases are Athlete’s foot, groin ringworm, body ringworm, nail infection, scalp ringworm etc.Yeast infection is also a type of fungal infection where disease like Interigo and Thrush occur.



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