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Viagra(sildenafil), Cialis(tadalafil), and Levitra(vardenafil) all act as potent PDE5A (an enzyme) inhibitors. Erectile Dysfunction, or impotence, may feel like an embarrassing problem for some men, however it is known to affect more than half of all men aged between 40 - 70. Erectile Dysfunction problems occur more regular in men with high bloody pressure, or men that suffer heart problems, as Erectile Dysfunction is caused by insufficient blood flow to the penis.
Most common cases of Erectile Dysfunction are due to the narrowing of the small arteries within the penis. In the past 10 years there have been major breakthroughs in the treatment of Erectile Dysfunction, with a number of different medications becoming available.
The most common tablets currently available are Viagra, Cialis, Levitra or the new Sildenafil (generic version of Viagra), which all help relieve the symptoms of erectile problems.
Erectile Dysfunction is considered to be a medical condition, so it is essential for you to seek treatment from your doctor before purchasing any tablets for your problem. In addition to prescription medications, traditional treatments and lifestyle changes, alternative treatments provide some helpful and beneficial options for men with ED. As the fastest growing consumer health information site a€” with 65 million monthly visitors a€” Healthlinea€™s mission is to be your most trusted ally in your pursuit of health and well-being.
For a long time treatment for impotence was restricted to penis injections, mechanisms that create voids or prostheses implanted through surgery. Normal erection To understand how the PDE-5 works, you must understand how a normal erection occurs. There are two widely vascularized cylindrical structures inside the penis, called corpora cavernosa.
When the corpora cavernosa is filled with blood it takes a signal from the central nervous system, releasing a substance called nitric oxide. PDE-5 chemical structure Not to go into details about complex biological and chemical mechanisms, we can say roughly that the substance responsible for the emission of nitric oxide action, which is responsible for the erection, is called Phosphodiesterase type 5 (PDE-5). Knowing now how erection works and how these drugs act, it is possible to imagine that Viagra or other PDE-5 inhibitors may not have an effect on some patients, especially on those with problems with the nerves and vessels of the penis.
Sildenafil pills Sildenafil, marketed under the name Viagra since 1998, was the first drug in the class of PDE-5 inhibitors to be launched.
Viagra is sold in tablets of 25 mg, 50mg or 100mg, with a dosage ranging from 25mg to 100mg per day, depending on the clinical evaluation. The action of Viagra starts after 30 minutes and lasts for up to four hours, but that does not mean that erection will continue during all this time. Sildenafil is a vasodilator and although preferably acts on the vessels in the penis, there is also an increase in nitric oxide causing a reduction in systemic blood pressure. Drugs used for prostate hypertrophy, terazosin and doxazosin, also have vasodilator and are also enhanced by the Viagra, which may cause hypotension. Patients with heart failure, Viagra should not be used without explicit medical clearance, as it may cause decompensation of the frame.
Some drugs alter the effect of Viagra and its consumption should also be avoided, including: Erythromycin, ketoconazole, cimetidine, itraconazole, rifampicin, phenytoin, indinavir and ritonavir. The most common side effects of sildenafil are headaches and dizziness caused by the effects of systemic vasodilation. There are other effects, which are rare, ant they include visual disturbances such as bluish vision, blurred or increased sensitivity to light. Priapism, which is a prolonged, painful erection, is a very rare event, but may occur after use of Viagra. Viagra is old and if you use it for long then it doesn't work that much,so better to use some alternative,some natural medicine like's really works great and it has zero side effects.
Originally Pfizer was testing the active ingredient in Viagra, sildenfail, for cardiovascular use and its ability to lower blood pressure. In 2011 a study was published stating low PDE5A expression allows for the pervasiveness of melanoma cells.
If you feel you are unable to achieve or maintain an erection when sexually excited, then you may be suffering from Erectile Dysfunction. ED is also associated with men with high cholesterol levels or diabetes, men with hormone problems, or after a serious injury or surgery.

These arteries in the penis are considerable smaller so the blood flow can become more of a problem quicker than with blood flow to the heart, or legs, which is why it is important to seek medical treatment if you feel you are suffering from Erectile Dysfunction, as it may be linked to other medical problems.
If you have been to see your GP, and have a prescription for Erectile Dysfunction tablets then simply choose ‘I have a prescription’ when ordering. They may have moved up to a more demanding position in their work, they often have started a family, bought a home, and gotten into debt. Both of which will support, guide, and inspire you toward the best possible health outcomes for you and your family. Since late 1990s, however, there has been a simple and convenient treatment for erectile dysfunction, drugs that inhibit Phosphodiesterase type 5 (PDE-5), commercially known as Viagra, Cialis and Levitra. When sexual stimulation occurs, blood flow to these structures increases, causing increased penis size and consequent compression of the penile veins. This neurotransmitter relaxes the blood vessels of the cavernous body, helping the entry of blood in it. There are drugs that inhibit PDE-5, which have a more prolonged action of nitric oxide, thus ensuring ease of the blood flow to the corpora cavernosa. The success rate is around 70%, being higher only for patients with psychological problems and lower for those with poorly controlled diabetes or pelvic nerve damage after prostate surgery. The tablet should ideally be taken on an empty stomach (at least 2 hours after the last meal) and 1 hour before an intercourse.
Sildenafil only helps erection to occur because it increases the lifetime of nitric oxide already produced, not directly affecting its production.
Patients who had a stroke, especially in the last six months, must also be careful with the use of sildenafil.
Erectile improvement with this combination is highly possible but there is still a high risk of toxicity. Every patient with continuous erection for more than four hours should call the emergency because there is risk of ischemia and thrombosis of the penis.
As Viagra, it is to be taken an hour before intercourse and preferably away from the last meal. There are no differences between the effectiveness of Cialis, Levitra and Viagra, but the former has some peculiarities: Cialis has a longer effect, which lasts for up to 36 hours, does not seem to cause the rare vision changes as Viagra and Levitra, and can be taken close to meals.
Earlier I used Cialis, but now, after re-reading the instruction - I found all my sores in the section of contra-indications. Now we have a new drug Cialis, its main difference is in softer and longer action, such as where "weekend pill", 1.5 - 2 days of action. Patients ended up reporting cases of long lasting erections, some refusing to return the medication for personal use. This was a beginning piece of evidence that current erectile dysfunction drugs inhibit an enzyme that helps protect the body from skin cancer. Even though a large number of men suffer from Erectile Dysfunction, 90% of men refuse to seek treatment. As well as this medication, it is also proven that an improvement in lifestyle can help to give stronger erections.
These are veins that are responsible for returning blood to the rest of the body and therefore, when they are compressed, they are unable to perform its role. Until there is nitric oxide in the corpora cavernosa, the penis will remain engorged with blood, and therefore, erect, when nitric oxide level falls, the erection ends. For example, men with low testosterone level cannot produce sufficient amounts of nitric oxide. Sildenafil is not a medicament for everyday use, the minimum interval between two dosages should be at least 24 hours. If there is sexual stimulation, there is no stimulus for the release of nitric oxide and erection, just as it typically occurs. The PDE-5 inhibitors in very high doses (above mentioned) can cause a stroke and a serious hypotension.
Priapism is a common side effect when Viagra is used recreationally by young people combined with other drugs such as ecstasy, cocaine and amphetamines. My husband and I'd like to give birth to the second child, but for the past seven months we were not a success.

So, does the difference between low dose Cialis from ordinary reduce the period or does it reduce the "strength" of the drug? ED drugs were born as a side effect, and as it turns out, they have more than a handful of side effects themselves. Later in 2014 a more comprehensive study was finalized involving an analysis of over 25,848 men taking sildenafil (Viagra).
When ordering in this way you will go through a set of medical questions that will be reviewed by our prescribing pharmacist to see if medication is suitable for your specific problem. This leads to blood retention in the corpora cavernosa, maintaining an erection, which is only interrupted when sexual stimulation ends. Erectile dysfunction medication side effects have included heart attacks, strokes, vision problems and hearing troubles. The results showed that Viagra nearly doubled the chance for men to develop the deadly skin cancer melanoma.
When your order has been approved your tablets will be dispensed from our UK registered pharmacy, supplying licensed medication manufactured in the UK, then sent out to you. When there is an orgasm or when the stimulus for the erection ends, the corpora cavernosa and the penis becomes empty and flaccid again.
The study also recommends further investigation into the link between melanoma and erectile dysfunction drugs that inhibit PDE5A.
A patient with diabetes and diseased vessels may be unable to supply enough blood for the penis to fill, even if there is enough nitric oxide. Food and Drug Administration ordered that warnings about vision loss be added to erectile dysfunction medication labels, leading to a series of lawsuits filed against erectile dysfunction drug manufacturers. As of yet the manufacturers of ED drugs have failed to warn consumers of this potential increase in risk for skin cancer.
Now a new series of lawsuits are being filed against the makers of Viagra, Cialis, and Levitra in connection with reports of an increased risk of skin cancer.
The manufacturers may be held liable in a lawsuit should you or anyone you know suffer from skin cancer related to the consumption of these erectile dysfunction drugs. They’re packed full of antioxidants to clear your system […]Anxiety EDHow Fear Causes Erection Problems (By Jason Brick) A fear based erection problem is called “Anxiety ED,” otherwise know as anxiety erectile dysfunction and it can affect men as strongly as circulatory issues do. Contact Loncar & Associates immediately for a free, confidential case evaluation using the form on the side or by calling toll free at 800-285-4878.
Viagra, Cialis, and Levitra skin cancer lawsuits are being evaluated on a contingency fee basis, meaning you pay nothing unless a recovery is obtained.
Not only that, but in many men there’s also a link between back pain and erectile dysfunction. As a matter of fact, several sources of back pain can cause ED, including… Tight hip flexors Pinched nerves Herniated discsBeet Juice For ErectionsI’ve been testing raw beet juice for erections for the last several weeks and the test has gone extremely well, to say the least. I had been using dry beet root juice powder from Amazon that you mix up with water and drink.
This provided some erection benefits, but the raw beet juice has outclassed […]Causes Of ED In Your 20’s and 30’sWhen I started my first site back in 2009 I was surprised how often I was contacted by twenty and thirty somethings complaining of ED. We spend a lot of time on this blog telling you about obscure herbal treatments and supplements that can help increase your libido and virility.
They’re proven techniques, and many have been known for their effects for […]Celery And Erectile DysfunctionThis is a guest post about celery and erectile dysfunction written by David Janes. Boosts nitric oxide Elevates sex drive Reduces platelet aggression Increases testosterone production And even makes you smell better to women Now here’s David….Dietary Fat and ErectionsI’ve been jacking around with my diet lately, especially my final meal of the day, to test its impact on morning erections.
And while I’m not much of a fan of tasteless low fat eating, I am becoming a fan for this particular meal.
Hi Mark, I have difficulty getting an erection. I have a new girlfriend and am having sex for the first time in a while. I’m 32, I […]Advertisement Recent CommentsSUBSCRIBESign up for my newsletter get a free copy of my e-Book along with notification when new articles are uploaded to the site!

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