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People with high blood pressure who blame their medication for impotence may be wrong, a study has found. It indicates that most impotent men treated for high blood pressure have blocked arteries and that their problems come when their blood pressure is lowered. However, some impotence experts argue that this still means that drugs which lower blood pressure indirectly cause erectile dysfunction. The study by Danish urologist Dr Jesper Jensen and his team at the University of Copenhagen found that a quarter of men who received medication for high blood pressure were impotent. Most were found to have atherosclerosis or fatty deposits, which blocked the arteries to the penis.
The different drugs the men were taking appeared to have little impact on whether the men suffered impotence, suggesting the condition is not a necessary side effect of the medication.
Most of the men were on the same blood pressure medication and many were on a combination of the drugs. Slightly more impotent men took ACE inhibitors and calcium channel blockers than those without problems.
The team found that 44% of the impotent men blamed their medication for their condition, but all had atherosclerosis.
It suggests that men with high blood pressure should be asked about impotence and advised about the treatments on offer. Ironically, Viagra was initially developed as a treatment for lowering blood pressure, but was found to be a more effective anti-impotence drug. Professor Alan Riley, chairman of the Impotence Association, said some of the older hypertension treatments directly caused impotence. And, despite claims to the contrary, he said many new treatments indirectly caused erectile dysfunction if high blood pressure was caused by blocked arteries. However, if high blood pressure was not a result of blocked arteries, he said, there was no reason why the newer drugs should cause impotence. He added that he knew of men who came off their high blood pressure drugs at weekends so that they could have sex.
Otherwise, the only way of reducing the risk of impotence linked to high blood pressure and blocked arteries is for sufferers to eat a low fat diet to lower their cholesterol. However, this will only stop arteries from clogging up more and will not prevent already existing problems. Print your Free Prescription Drug Coupon Card and save up to 75% off all FDA approved drugs at pharmacies nationwide.
Alzheimer's disease (AD), also known in medical literature as Alzheimer disease, is the most common form of dementia.
Most often, AD is diagnosed in people over 65 years of age, although the less-prevalent early-onset Alzheimer's can occur much earlier. Although Alzheimer's disease develops differently for every individual, there are many common symptoms.
As the disease advances, symptoms can include confusion, irritability and aggression, mood swings, trouble with language, and long-term memory loss.
Because AD cannot be cured and is degenerative, the sufferer relies on others for assistance.
There is no cure for Alzheimer's disease; available treatments offer relatively small symptomatic benefit but remain palliative in nature. Reduction in the activity of the cholinergic neurons is a well-known feature of Alzheimer's disease. Glutamate is a useful excitatory neurotransmitter of the nervous system, although excessive amounts in the brain can lead to cell death through a process called excitotoxicity which consists of the overstimulation of glutamate receptors.
Antipsychotic drugs are modestly useful in reducing aggression and psychosis in Alzheimer's disease with behavioural problems, but are associated with serious adverse effects, such as cerebrovascular events, movement difficulties or cognitive decline, that do not permit their routine use.
Donepezil, marketed under the trade name Aricept by its developer Eisai and partner Pfizer, is a centrally acting reversible acetylcholinesterase inhibitor. What is hypertension?Hypertension, or high blood pressure, is a common condition that will catch up with most people who live into older age.
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There is no cure for the disease, which worsens as it progresses, and eventually leads to death. Early symptoms are often mistakenly thought to be 'age-related' concerns, or manifestations of stress. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) to treat the cognitive manifestations of AD: four are acetylcholinesterase inhibitors (Tacrine, Rivastigmine, Galantamine and Donepezil) and the other (memantine) is an NMDA receptor antagonist.
Acetylcholinesterase inhibitors are employed to reduce the rate at which acetylcholine (ACh) is broken down, thereby increasing the concentration of ACh in the brain and combating the loss of ACh caused by the death of cholinergic neurons. Excitotoxicity occurs not only in Alzheimer's disease, but also in other neurological diseases such as Parkinson's disease and multiple sclerosis.
Its main therapeutic use is in the palliative treatment of mild to moderate Alzheimer's disease. It is intended for general information purposes only and does not address individual circumstances. These coupons are pre-activated and can be used immediately to save up to 75% on your prescription drugs.
It was first described by German psychiatrist and neuropathologist Alois Alzheimer in 1906 and was named after him.


Alzheimer's disease is known for placing a great burden on caregivers; the pressures can be wide-ranging, involving social, psychological, physical, and economic elements of the caregiver's life. Cholinesterase inhibitors approved for the management of AD symptoms are donepezil (brand name Aricept), galantamine (Razadyne), and rivastigmine (branded as Exelon and Exelon Patch).
When it's too high, it increases the heart's workload and can cause serious damage to the arteries.
It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health.
When AD is suspected, the diagnosis is usually confirmed with tests that evaluate behaviour and thinking abilities, often followed by a brain scan if available. Since the disease is different for each individual, predicting how it will affect the person is difficult. There is evidence for the efficacy of these medications in mild to moderate Alzheimer's disease, and some evidence for their use in the advanced stage. It acts on the glutamatergic system by blocking NMDA receptors and inhibiting their overstimulation by glutamate. Over time, uncontrolled high blood pressure increases the risk of heart disease, stroke and kidney disease.
Never ignore professional medical advice in seeking treatment because of something you have read on the BootsWebMD Site.
AD develops for an unknown and variable amount of time before becoming fully apparent, and it can progress undiagnosed for years. As of 2012, more than 1000 clinical trials have been or are being conducted to find ways to treat the disease, but it is unknown if any of the tested treatments will work. Memantine has been shown to be moderately efficacious in the treatment of moderate to severe Alzheimer's disease. Hypertension harmHigh blood pressure is sometimes called a silent killer because it usually causes no symptoms. On average, the life expectancy following diagnosis is approximately seven years Fewer than three percent of individuals live more than fourteen years after diagnosis.
Mental stimulation, exercise, and a balanced diet have been suggested as possible ways to delay symptoms in healthy older individuals, but they have not been proven as effective. The use of these drugs in mild cognitive impairment has not shown any effect in a delay of the onset of AD. The most common side effects are nausea and vomiting, both of which are linked to cholinergic excess. Reported adverse events with memantine are infrequent and mild, including hallucinations, confusion, dizziness, headache and fatigue.
Internally, it can quietly damage the heart, blood vessels, eyes, brain and kidneys if left untreated. These side effects arise in approximately 10a??20% of users and are mild to moderate in severity. The combination of memantine and donepezil has been shown to be "of statistically significant but clinically marginal effectiveness". Less common secondary effects include muscle cramps, decreased heart rate (bradycardia), decreased appetite and weight, and increased gastric acid production.
The lower number (diastolic) measures pressure at rest between heartbeats, when the heart refills with blood. Occasionally, kidney or adrenal gland disease can lead to hypertension but in most cases, the underlying cause of hypertension is unknown. Prehypertension: A warning signPrehypertension is where blood pressure is consistently just above the normal level, falling anywhere between 120 and 139 for systolic pressure or 80 to 89 for the diastolic pressure. People in this range have twice the risk of developing heart disease than those with a lower reading. This is why it's important to get your blood pressure checked on a regular basis as often as advised. Who gets high blood pressure?High blood pressure becomes more common for both men and women with increasing age. You have a greater risk if a close family member has high blood pressure or if you have diabetes.
Hypertension and racePeople of African-Caribbean origin are more likely to develop hypertension - and to develop it at a younger age. Hypertension and saltSalt can raise blood pressure by causing the body to retain fluid, which leads to a greater burden on the heart. Government advice is that adults should consume no more than 6g of salt a day - around one full teaspoon. Hypertension and stressStress can make your blood pressure spike, but it's unclear whether it directly causes high blood pressure as an ongoing condition.
However, stress may lead to other unhealthy habits, such as an unhealthy diet, alcohol use or smoking, which can contribute to high blood pressure and heart disease. Hypertension and weightBeing overweight places a strain on your heart and increases your risk of high blood pressure. The NHS recommends that men should not regularly have more than 3-4 units a day, and women should not regularly have more than 2-3 units a day. Hypertension and caffeineIf caffeine can make you jittery, can it also raise your blood pressure? It might have a temporary effect, but studies haven't shown any link between caffeine and the development of hypertension. However, the NHS suggests restricting your caffeine consumption to fewer than five cups of coffee or tea a day to try and avoid blood pressure increases.


Hypertension and pregnancyGestational hypertension is a kind of high blood pressure that occurs in the second half of pregnancy. Without treatment, it may lead to a serious condition called pre-eclampsia that endangers both the mother and baby. The condition can limit blood and oxygen flow to the baby and can affect the mother's kidneys and brain.
Hypertension and medicationCold and flu medicines that contain decongestants are one of several classes of medicine that can cause your blood pressure to rise. Others include NSAID painkillers such as ibuprofen, steroids, diet pills, contraceptive pills and some antidepressants.
If you have high blood pressure, talk to your doctor about what medicines and supplements you are taking that may affect blood pressure. To get a more accurate reading, take your blood pressure at home, chart your readings, and share them with your doctor. It is also a good idea to bring in your home monitor for a check of the device and your technique.
Your doctor may suggest you use an ambulatory blood pressure monitoring device for 24 hours.
This consists of wearing a blood pressure cuff attached to an automatic blood pressure machine which takes a series of readings during your normal daily life away from the stress of the surgery. Hypertension and childrenWhile hypertension is more often a problem for adults, even children can have high blood pressure.
Children are at greater risk if they are overweight, have a family history of the condition or if they're of African-Caribbean descent. Treatment: The DASH dietYou may be able to lower your blood pressure by switching to a better diet.
The DASH diet - Dietary Approaches to Stop Hypertension - involves eating more fruit, vegetables, whole-grain foods, low-fat dairy products, fish, poultry and nuts. Adults should do at least 30 minutes of moderate-intensity exercise at least five days a week.
Muscle-strengthening activities are recommended at least two days a week and should work all major muscle groups. Treatment: DiureticsDiuretics are one of the medication choices if diet and exercise changes aren't enough. Also called "water pills," they help the body shed excess salt and water to lower blood pressure.
Some diuretics may deplete your body's potassium, causing muscle weakness, leg cramps and fatigue. Treatment: ACE inhibitorsACE (angiotensin converting enzyme) inhibitors reduce your body's supply of angiotensin II, a substance that makes blood vessels contract and narrow. The result is more relaxed, open (dilated) arteries, as well as lower blood pressure and less effort for your heart. Treatment: ARBsInstead of reducing your body's supply of angiotensin II, ARBs (angiotensin II receptor blockers) block receptors for angiotensin, as if placing a shield over a lock. This blockade prevents angiotensin's artery-tightening effects, and lowers your blood pressure. Possible side effects include dizziness, muscle cramps, insomnia and high levels of potassium. Treatment: Calcium channel blockersCalcium channel blockers slow the movement of calcium into the cells of the heart and blood vessels. Since calcium causes stronger heart contractions, these medications ease the heart's contraction and relax the blood vessels.
Take them with food or milk and avoid grapefruit juice and alcohol because of possible interactions. Treatment: Beta-blockersBeta-blockers work by slowing the heart rate, which means that the heart doesn't have to work as hard.
They are also used to treat other heart conditions, such as an abnormal heart rate called arrhythmia. Side effects can include insomnia, dizziness, fatigue, cold hands and feet, and erectile dysfunction. Treatment: Other medicationsOther medications that relax the blood vessels include vasodilators, alpha blockers and central agonists. Side effects can include dizziness, a fast heart beat or heart palpitations, headaches or diarrhoea. Your doctor may suggest them if other blood pressure medications are not working well enough or if you have another condition.
Treatment: Complementary therapiesMeditation can put your body into a state of deep rest, which can lower your blood pressure. These relaxation techniques should be combined with other lifestyle changes, such as improved diet and regular exercise. Be aware that herbal therapies may interact with other medications you take, and some herbs actually raise blood pressure.
If you keep it under control, you can reduce your risk of stroke, heart disease and kidney failure.



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