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As I mentioned in a previous blog post, I am taking a nutrition class in college right now. The Vitamin B12 is also known as Cobalamin and is a water soluble, complex vitamin, which is found, in the common foods that we eat, like the meat products, dairy products, fish, etc.
The Vitamin b12 shots are prescribed for patients who are suffering from Vitamin B12 deficiency and also in cases of pernicious anemia. Generally doctors prescribe to fulfill the daily requirement of Vitamin B12 from the food that we generally have.
This is used in a regular basis by the slimming centers as a part of their weight loss program.
This article educates us what is Vitamin D deficiency, symptoms, importance of Vitamin D, causes, treatment and suggested best helpful supplements. A few years ago, Vitamin D was thought to do nothing more than allow calcium to be absorbed for good bone health. Vitamin D deficiency can occur for a number of reasons:You don't consume the recommended levels of the vitamin over time.
Treatment for vitamin D deficiency involves getting more vitamin D -- through diet and supplements. Wouldn’t it be great if one vitamin could build stronger bones and protect against diabetes, multiple sclerosis, cancer, heart disease, and depression?
Some studies have shown a link between a low vitamin D level and type 1 and type 2 diabetes . Vitamin D plays a role in brain development and function, and low levels of vitamin D have been found in patients with depression. Using sunscreen can interfere with getting vitamin D, but abandoning sunscreen can significantly increase your risk for skin cancer. There's a simple blood test used to check your vitamin D level, called the 25-hydroxyvitamin D test. The recommended dietary allowance for vitamin D is 600 IU (international units) per day for adults up to age 70. Some researchers suggest taking far more vitamin D than the 600 IU daily guideline for healthy adults. Low levels of vitamin D have been linked to a greater risk of heart attack, stroke, and heart disease. Institute of Medicine: “Dietary Reference Intakes for Calcium and Vitamin D,” November 30, 2011. World Health Organization, International Agency for Research on Cancer, “Vitamin D and Cancer,” 2008.
Pemphigus is a collection of skin disorders which are very rare and which cause the skin or mucous membranes to blisters – such as on the genitals or mouth. These conditions can develop at any age but most often occur in individuals in middle age or older. Pemphigus is normally a condition which is chronic and is controlled best when diagnosis and treatment is early.
An individual should see their primary care physician if they develop any blisters on the skin or inside the mouth.
Just exactly what causes pemphigus is not known but it is believed to be an autoimmune disorder.
Usually when the body is functioning normally, the systems of immunity will attacks any foreign bodies or invaders for instances bacteria or viruses.
Often, pemphigus grows as a side effect of certain drugs for example blood pressure medication, or chelating agents. Most treatments have a goal of reducing the symptoms and signs and also to prevent any complications. Corticosteroids –  The main treatment is normally with corticosteroids like prednisone.
Immunosuppressants – These are drugs such as azathioprine, methotrexates or mycophenolate which can help to keep the immune system from attacking the healthy tissues. Antivirals, antifungal medications as well as antibiotics – These can be prescribed to prevent or control infections, usually infections from staphylococcus bacteria or herpes viruses. Pemphigus which is widespread can mean a stay in the hospital where treatment similar to severe burn treatment can be applied. Fluids – Because of the loss of fluids due to oozing of these sores, the individual can receive fluids thru an IV set up, as well as electrolytes such as potassium, calcium as well as sodium and also proteins. Therapeutic plasmapheresis – With this process, the fluid called plasma is removed from other parts of the blood by a device which is called a cell separator. For many individuals, the treatment will cause all of the blisters or sores to leave completely in a few months and then treatment may be discontinued.
If you have blisters in the mouth, talk with your dentist about maintaining proper as well as good oral health.
This website is for informational purposes only and Is not a substitute for medical advice, diagnosis or treatment. Please note that we are unable to respond back directly to your questions or provide medical advice. As the fastest growing consumer health information site a€” with 65 million monthly visitors a€” Healthlinea€™s mission is to be your most trusted ally in your pursuit of health and well-being. One of Vitamin A’s pro-vitamins is Carotene, also known as Carotin and Beta-Carotene. You can also get Carotene from a few other sources like sweet potatoes, squash and dark green leafy vegetables. Although this vitamin is good for your overall health, but at times it can interfere with some drugs that you might be taking, so it is advisable to inform your doctor about any injection that you might have taken of this vitamin. But if the doctor sees that you still have the deficiency of this vitamin, then this is because of the fact that some people are not able to absorb this vitamin due to the presence of some “intrinsic factors” in the stomach.
But the fact is that this vitamin by itself does not reduce your weight, but it increases the metabolism of your body and also increases the energy of the body. New research suggests that vitamin D may be one of the best vitamins of all for your body as scientists have uncovered up to 2,000 different genes-roughly one-sixth of the human genome-that are regulated by the nutrient.
This is likely if you follow a strict vegan diet, because most of the natural sources are animal-based, including fish and fish oils, egg yolks, fortified milk, and beef liver.Your exposure to sunlight is limited. Although there is no consensus on vitamin D levels required for optimal health -- and it likely differs depending on age and health conditions -- a concentration of less than 20 nanograms per milliliter is generally considered inadequate, requiring treatment.Guidelines from the Institute of Medicine increased the recommended dietary allowance (RDA) of vitamin D to 600 international units (IU) for everyone ages 1-70, and raised it to 800 IU for adults older than age 70 to optimize bone health. For years, experts suspected a link between sunlight, vitamin D levels, and this autoimmune disorder that damages the nerves.
But studies don't show that Vitamin D supplementation will help reduce the symptoms of depression.  The best bet is to talk with your doctor about what might help reduce the symptoms of depression. Fish such as salmon, swordfish, or mackerel is one big exception and can provide a healthy amount of vitamin D in one serving. If you still need help getting enough, there are two kinds of supplements: D2 (ergocalciferol), which is the type found in food, and D3 (cholecalciferol), which is the type made from sunlight.
So it's worth looking for other sources of vitamin D in place of prolonged, unprotected exposure to the sun.
Breastfed babies need 400 IU of vitamin D until they're weaned to fortified formula and can drink at least one liter (about 4 ? cups) every day. But newer studies suggest that people with higher levels of vitamin D in their blood may have a lower risk for colon cancer.
Still, it’s not clear whether boosting vitamin D will reduce heart risks and how much vitamin D is needed. Researchers found that older people with vitamin D deficiency performed poorly on tests of memory, attention, and reasoning compared to people with enough vitamin D in their blood.


It is intended for general informational purposes only and does not address individual circumstances. Both of which will support, guide, and inspire you toward the best possible health outcomes for you and your family.
But they are important for your health, and if you aren’t getting enough of them you might be in trouble.
Then such people are required to take Vitamin b12 shots to maintain the required balance of this vitamin in the body. This enables the body to burn the food that you have consumed at a faster rate, and helps in reducing weight. But it is advisable to lose your weight by following a healthy lifestyle, and exercise regularly, for a prolonged effect.
We invite all the passionate writers and bloggers in similar niche who are interested in getting known through our blog. Because the body makes vitamin D when your skin is exposed to sunlight, you may be at risk of deficiency if you are homebound, live in northern latitudes, wear long robes or head coverings for religious reasons, or have an occupation that prevents sun exposure.You have dark skin. Vitamin D is a fat-soluble vitamin in a family of compounds that includes vitamins D1, D2, and D3. Researchers have high hopes for vitamin D -- which comes from our skin's reaction to sunlight, a few foods, and supplements. In older adults, a daily dose of "D" and calcium helps to prevent fractures and brittle bones.
One newer clue comes from a study of a rare gene defect that leads to low levels of vitamin D – and a higher risk of MS. There's not enough proof for doctors to recommend taking this supplement to prevent diabetes.
It's not clear whether obesity itself causes a low vitamin D level or if it's the other way around. Some researchers recommend much higher doses of vitamin D, but too much vitamin D can hurt you. Very high doses of vitamin D can raise your blood calcium level, causing damage to blood vessels, heart, and kidneys.
If you take digoxin, a heart medicine, too much vitamin D can raise the level of calcium in your blood and lead to an abnormal heart rhythm. Very high levels of vitamin D in the blood can actually harm blood vessels and the heart by increasing the amount of calcium in the bloodstream. Still, better studies are needed to learn if vitamin D supplements could prevent dementia or slow mental decline. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. This is understandable though, because they all come from dark green leafy vegetables (like spinach). The problem is that most of us are not spending enough time in the sun for our bodies to produce Vitamin D, nor do our foods any longer provide what we need.Vitamin D is essential for strong bones, because it helps the body use calcium from the diet.
The pigment melanin reduces the skin's ability to make vitamin D in response to sunlight exposure. It can affect as many as 2,000 genes in the body.Vitamin D has several important functions. Children need "D” to build strong bones and prevent rickets, a cause of bowed legs, knock knees, and weak bones.
Despite these links, there's not enough evidence to recommend vitamin D for the prevention or treatment of MS. But one small study of dieters suggests that adding vitamin D to a calorie-restricted diet may help overweight people with low vitamin D levels lose weight more easily.
In children, a severe deficiency can lead to rickets and symptoms of soft bones and skeletal problems. Children with some chronic diseases such as cystic fibrosis may be at increased risk for vitamin D deficiency. It's important to discuss your use of vitamin D supplements with your doctor or pharmacist.
The VITAL Study -- a Harvard university study -- of vitamin D and omega-3 is following 20,000 volunteers to find answers. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. After more studying, scientists found out that Vitamin B wasn’t one vitamin, but a dozen different vitamins that had a lot of similarities. There aren’t any other things that happen when you eat too much (as far as scientists know). Traditionally, vitamin D deficiency has been associated with rickets, a disease in which the bone tissue doesn't properly mineralize, leading to soft bones and skeletal deformities. Some studies show that older adults with darker skin are at high risk of vitamin D deficiency.Your kidneys cannot convert vitamin D to its active form. Perhaps the most vital are regulating the absorption of calcium and phosphorous, and facilitating normal immune system function.
But cloudy days, the low light of winter, and the use of sun block (important to avoid skin cancer and skin aging) all interfere. High doses can cause nausea, vomiting, loss of appetite, excessive thirst, muscle aches, or more serious symptoms. In the meantime, a healthy body weight, regular exercise, and the diet guidelines of the American Cancer Society may help prevent cancer. This happens to a lot of the elderly because they don’t eat as many vegetables due to the difficulty of chewing them. In today’s podcast I will share with you science that will show you just how harmful vitamin D supplements can be for your health, so you can make an educated decision for yourself and your family. As people age, their kidneys are less able to convert vitamin D to its active form, thus increasing their risk of vitamin D deficiency.Your digestive tract cannot adequately absorb vitamin D.
Recently though, they decided that was too confusing and gave them each their own names, and they also realized that they had doubled a few of them up.
Certain medical problems, including Crohn's disease, cystic fibrosis, and celiac disease, can affect your intestine's ability to absorb vitamin D from the food you eat.You are obese. Vitamin D has been shown in recent studies to help promote immune health, help support healthy heart function, help muscle function, bone health and skin health.Mechanism of ActionBiosynthesisVitamin D3 (cholecalciferol) is produced through the action of ultraviolet irradiation (UV) on its precursor 7-dehydrocholesterol.
Vitamin D is extracted from the blood by fat cells, altering its release into the circulation.
D.  10 Harmful Vitamin D Supplement Side Effects You Did Not Know About You can listen to the Vegalicious Podcast by using the player below or subscribe on iTunes, Stitcher Radio or Google Play Music. Vitamin D3 can be made by exposure of the skin to UVB, or by exposing milk directly to UV (one commercial method). D3 is also found in oily fish and cod liver oil.Vitamin D2 is a derivative of ergosterol, a membrane sterol named for the ergot fungus, which is produced by some kinds of phytoplankton, invertebrates, yeasts, and higher fungi such as mushrooms. The vitamin ergocalciferol (D2) is produced in all of these organisms from ergosterol, in response to UV irradiation. D2 is not produced by green land plants or vertebrates, because they lack the precursor ergosterol.
The biological fate for producing 25(OH)D from vitamin D2 is expected to be the same as for 25(OH)D3, although some controversy exists over whether or not D2 can fully substitute for vitamin D3 in the human diet.Photochemistry The photochemistry of vitamin D biosynthesis in animal and fungi Thermal isomerization of previtamin D3 to vitamin D3 The transformation that converts 7-dehydrocholesterol to vitamin D3 occurs in two steps. First, 7-dehydrocholesterol is photolyzed by ultraviolet light in a 6-electron conrotatory ring-opening electrocyclic reaction; the product is previtamin D3. Second, previtamin D3 spontaneously isomerizes to vitamin D3 (cholecalciferol) in an antarafacial sigmatropic hydride shift.


At room temperature, the transformation of previtamin D3 to vitamin D3in an organic solvent takes about 12 days to complete. The conversion of previtamin D3 to vitamin D3 in the skin is about 10 times faster than in an organic solvent EvolutionPhotosynthesis of vitamin D in the ocean by phytoplankton (such as coccolithophore and Emiliania huxleyi) has existed for more than 500 million years and continues to the present. Although primitive vertebrates in the ocean could absorb calcium from the ocean into their skeletons and eat plankton rich in vitamin D, land animals required another way to satisfy their vitamin D requirement for a calcified skeleton without relying on plants. However, vitamin D deficiency has become a worldwide issue in the elderly and remains common in children and adults.
Deficiency results in impaired bone mineralization and bone damage which leads to bone-softening diseases, including:RicketsRickets, a childhood disease, is characterized by impeded growth and soft, weak, deformed long bones that bend and bow under their weight as children start to walk. This condition is characterized by bow legs, which can be caused by calcium or phosphorus deficiency, as well as a lack of vitamin D; today, it is largely found in low-income countries in Africa, Asia, or the Middle East and in those with genetic disorders such as pseudovitamin D deficiency rickets. Rickets was first described in 1650 by Francis Glisson, who said it had first appeared about 30 years previously in the counties of Dorset and Somerset. In 1857, John Snow suggested rickets, then widespread in Britain, was being caused by the adulteration of bakers' bread with alum.
The role of diet in the development of rickets was determined by Edward Mellanby between 1918–1920. Nutritional rickets exists in countries with intense year-round sunlight such as Nigeria and can occur without vitamin D deficiency.
Although rickets and osteomalacia are now rare in Britain, outbreaks have happened in some immigrant communities in which osteomalacia sufferers included women with seemingly adequate daylight outdoor exposure wearing Western clothing. Having darker skin and reduced exposure to sunshine did not produce rickets unless the diet deviated from a Western omnivore pattern characterized by high intakes of meat, fish, and eggs, and low intakes of high-extraction cereals. Vitamin D deficiency remains the main cause of rickets among young infants in most countries, because breast milk is low in vitamin D and social customs and climatic conditions can prevent adequate sun exposure. In sunny countries such as Nigeria, South Africa, and Bangladesh, where the disease occurs among older toddlers and children, it has been attributed to low dietary calcium intakes, which are characteristic of cereal-based diets with limited access to dairy products. Rickets was formerly a major public health problem among the US population; in Denver, where ultraviolet rays are about 20% stronger than at sea level on the same latitude, almost two-thirds of 500 children had mild rickets in the late 1920s.
An increase in the proportion of animal protein in the 20th century American diet coupled with increased consumption of milk fortified with relatively small quantities of vitamin D coincided with a dramatic decline in the number of rickets cases. Also, in the United States and Canada, vitamin D-fortified milk, infant vitamin supplements, and vitamin supplements have helped to eradicate the majority of cases of rickets for children with fat malabsorption conditions.OsteomalaciaOsteomalacia is a disease in adults that results from vitamin D deficiency. Characteristics of this disease are softening of the bones, leading to bending of the spine, bowing of the legs, proximal muscle weakness, bone fragility, and increased risk for fractures.
Osteomalacia reduces calcium absorption and increases calcium loss from bone, which increases the risk for bone fractures.
The effects of osteomalacia are thought to contribute to chronic musculoskeletal pain, There is no persuasive evidence of lower vitamin D levels in chronic pain sufferers.Influence of skin pigmentationSome research shows dark-skinned people living in temperate climates have lower vitamin D levels.
Dark-skinned people may be less efficient at making vitamin D because melanin in the skin hinders vitamin D synthesis; however, a recent study has found novel evidence that low vitamin D levels among Africans may be due to other reasons. Black women have an increase in serum parathyroid hormone at a lower 25(OH)D level than white women.
A large-scale association study of the genetic determinants of vitamin D insufficiency in Caucasians found no links to pigmentation.However, the uniform occurrence of low serum 25(OH)D in Indians living in India and Chinese in China, does not support the hypothesis that the low levels seen in the more pigmented are due to lack of synthesis from the sun at higher latitudes.
High Doses of Vitamin D Do Not Reduce Respiratory Infections A study in the Journal of the American Medical Association showed that patients who took 100,000 IU’s of vitamin D monthly for 18 months developed the same number of upper respiratory infections as patients who took a placebo. Vitamin D toxicity is not caused by sunlight exposure, but can be caused by supplementing with high doses of vitamin D. If hypercalcemia is not treated, it results in excess deposits of calcium in soft tissues and organs such as the kidneys, liver, and heart, resulting in pain and organ damage. Pregnant or breastfeeding women should consult a doctor before taking a vitamin D supplement.
The FDA advised manufacturers of liquid vitamin D supplements that droppers accompanying these products should be clearly and accurately marked for 400 international units (IU). In addition, for products intended for infants, the FDA recommends the dropper hold no more than 400 IU. Proteinuria, urinary casts, azotemia, and metastatic calcification (especially in the kidneys) may develop.
Other symptoms of vitamin D toxicity include mental retardation in young children, abnormal bone growth and formation, diarrhea, irritability, weight loss, and severe depression. Vitamin D toxicity is treated by discontinuing vitamin D supplementation and restricting calcium intake. Exposure to sunlight for extended periods of time does not normally cause vitamin D toxicity.
Within about 20 minutes of ultraviolet exposure in light-skinned individuals (three to six times longer for pigmented skin), the concentrations of vitamin D precursors produced in the skin reach an equilibrium, and any further vitamin D produced is degraded.Published cases of toxicity involving hypercalcemia in which the vitamin D dose and the 25-hydroxy-vitamin D levels are known all involve an intake of ?40,000 IU (1,000 ?g) per day.
There were no differences between the groups in the risk for upper respiratory infections or for flu-like symptoms such as sore throat, cough, muscle aches or headaches. Recommending supplementation, when those supposedly in need of it are labeled healthy, has proved contentious, and doubt exists concerning long term effects of attaining and maintaining high serum 25(OH)D by supplementation. This was the case even for participants who had low vitamin D levels at the beginning of the study.
The researchers also stated that the flu vaccine provided no significant benefit. (14) Toxic Side Effects of Vitamin D Supplements 9. High Vitamin D Levels Increase Risk of Allergy A group of German researchers determined that pregnant women with lower vitamin D levels delivered children who were less likely to develop allergies than mothers with higher vitamin D levels during pregnancy.
Children of women who consumed more vitamin D during pregnancy were more likely to have IgE responses to egg whites, milk protein, wheat flour, peanuts and soy. Regulatory T cells are important in regulating response to allergens, protecting against the development of allergies.
The higher the blood levels of vitamin D in the mothers and their children, the lower the levels of regulatory T cells were.
The researchers concluded that excess vitamin D could suppress the development of proper immune function and increase the risk of allergy. Other Side Effects Supplemental D can cause: excessive thirst metal taste in the mouth loss of appetite eight loss nausea fatigue pain in the bones osteoporosis vision problems itchy skin vomiting diarrhea constipation muscle damage kidney stones hypercholesterolemia hypercalcemia mental retardation damage to the eyes and heart allergies, and cancer. Just 10-15 minutes in the sun is the equivalent of taking between 15,000 and 20,000 IU’s of Vitamin D, but without the potential for toxicity of supplements. Hollick cited research indicating that the more sun exposure an individual gets as a child and young adult, the less likely he will be to die from melanoma if he develops it later in life. Those that had the most exposure had a 35% reduction in risk as opposed to those with the least exposure. People who got lots of sun on weekends and holidays had less than half the incidence of NHL of those who stayed indoors. I recommend that everyone get exposure to the sun regularly, and allow their bodies to produce it as intended. I acknowledge that there are people with vitamin D deficiencies which might find vitamin D supplementation helpful in boosting their levels; for example, elderly patients confined to bed in nursing homes.
There is little evidence to support massive testing and supplementation for the general public as a means for addressing health issues caused by diet and lifestyle choices. Now that you have learned the importance of proper ways to get vitamin D, and the 21 reasons to avoid supplementation, make sure to share this articles with others. If you have a vitamin D supplementation story you want to share, leave a note under this post.



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