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Caused by either too little von Willebrand Factor or von Willebrand factor that is defective. There are bleeding scoring systems to help determine likelihood of bleeding disorders… but they are not validated in kids.
Crush tablets in 10-15ml of water and have patient hold that in their mouth for 5 min before swallowing. Has longer half-life, more potency, and lower toxicity than Aminocaproic acid and is preferred. A bleeding child is a cause of great concern and often, panic, for parents and pediatricians alike.
Patients with bleeding disorders such as hemophilia A, hemophilia B, and von Willebrand disease (VWD) are routinely treated at home, with their care managed in specialized centers.
I enjoy taking care of patients and I finding it endlessly rewarding to help train others to do the same.
Ped EM MorselsEnhance and refine your understanding of Pediatric Emergency Medicine and augment the care of pediatric patients.
When bleeding occurs due to a wound or vascular trauma, specialized cells called thrombocytes (platelets) are chemically activated to collect at the site of the injury and begin to form a blood clot. All dogs regardless of breed that exhibit symptoms of prolonged bleeding times or spontaneous bleeding may be tested for plasma levels of vWf to confirm a diagnosis. Plasma vWf levels are compared to “normal” dog levels and are expressed in terms of a percentage of normal. In addition to the plasma vWf test, a complete blood count will be used to detect subsequent anemia that may result from bleeding. The treatment for von Willebrand’s Disease, in the case of active bleeding or as a preventive measure before surgery, requires the administration of von Willebrand’s factor.

A hormone called Desmopressin Acetate (DDAVP) has been used successfully to stimulate the release of von Willebrand’s factor in positive animals. A von Willebrand’s positive dog may be susceptible to recurrence of bleeding even after treatment.
We have recently covered hemophilia, ITP, and hemorrhagic disease of the newborn, but let us turn our attention to the most prevalent bleeding disorder: Von Willebrand Disease.  Certainly, making the diagnosis of von Willebrand disease is not necessarily a common goal in the ED, but knowing how to deal with it is! Causes of bleeding could be trivial or secondary to an underlying bleeding disorder or a potentially serious systemic illness.
In emergency situations, these patients often present to their local emergency department (ED), where their management can represent a challenge to the emergency physicians and staff who rarely encounter them. Based on etiology, they can be categorized into disorders affecting platelets or the coagulation cascade and can be inherited or acquired.
This year in the 2013 Reporters Without Borders World Press Freedom Index, and for the third year running, Finland has distinguished itself as the country that most respects media freedom. For instance, Aland Island eye disease (AIED), also known as Forsius-Eriksson syndrome, is an X-linked recessive retinal disease characterized by a combination of fundus hypopigmentation, decreased visual acuity, nystagmus, astigmatism, protan color vision defect, progressive myopia, and defective dark adaptation. The gene locus for AIED has been mapped to the pericentromeric region of the X-chromosome [2]. It is named after Henrik Forsius, Finnish ophthalmologist and Aldur Wictor Eriksson, Finnish human geneticist. It is named ?land Island eye disease because it is reported first and common in land which is a group of islands in the Bay of Finland, between Finland and Sweden. However, one of the commonest eponym linked to Finland mentioned in dermatology literature and the literature of medicine in general is Von Willebrand's disease (vWD). It is characterized by a deficiency in the clotting protein called von Willebrand?s Factor; the most common symptom is prolonged bleeding time.

However the latter may be a manifestation of a hereditary or acquired qualitative or quantitative platelet disorder, disturbance of the vascular or supporting structure, or it may be due to one of several acquired systemic disorders3. 1) is a Finnish internist, born in Vasa; a seaport city located in western Finland and died in, Pern?. He discovered the most common inherited bleeding disorder while studying the genetic traits of a family in the ?land Islands in Finland [4-7].
Von Willebrand published two papers on Physiology and Clinical Management in Treatment with Hot Air. Throughout his lifetime he maintained his interest in the latter form of treatment as well as in metabolic disorders and haematological problems. He focused on blood changes during muscular exercise, metabolism and obesity, as well as carbon dioxide and water exchange through the human skin. In 1925, he examined a 5-year-old girl with a history of bleeding who had been brought to Helsinki for treatment [5]. Von Willebrand was curious to know more, so he traveled to the land Islands to study the disease in depth. He mapped the family pedigree and found that 23 of the 66 family members had bleeding problems.
As he studied the disease more, he came to believe that platelets were involved, so he renamed it ?constitution-al thrombopathy?.

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21.08.2014 admin

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