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Researchers recently discovered genetic mutations that could reduce the risk of Type 2 diabetes.
Reducing your risk of diabetes soon could be possible, if drug companies can build on groundbreaking genetic research and design the appropriate therapy. Sometimes a loss-of-function mutation can cause a disease, such as cystic fibrosis, but others can protect against disease.
Approximately 300 million people in the world have Type 2 diabetes, and those numbers are rapidly escalating.
Incidence and preventability of adverse drug events among older adults in the ambulatory setting. The costs associated with adverse drug events among older adults in the ambulatory setting. Corona man is working to have felonies reclassified as misdemeanors so he can get a college education and better job.
Freddie Harris, 55, of Corona is hoping to go to college and get a better job now that his criminal record is cleaner. Exceptions: People are not eligible to have their felonies reclassified if they have convictions for other serious or violent felonies such as homicide, attempted homicide, rape or child molestation, or who are registered sex offenders or have been convicted of a crime punishable by life imprisonment or death.
How to apply: Requests to have a crime reclassified must go through the court in the county where the case was tried. Even with four years of sobriety under his belt and his criminal past behind him, Freddie Harris of Corona still struggles. A record riddled with felony drug convictions and prison time has made it tough for the 55-year-old to hold down a job, get an education or secure stable housing for him and his family. Harris is among 3,396 people in Riverside County and 72,624 people statewide who applied between November 2014 and March 2016 to have their felony convictions reclassified as misdemeanors, according to the Judicial Council of California. Temecula-based defense attorney Mike Donaldson, who frequently works with people seeking to have their felonies reclassified under Prop. Harris was plunged into the criminal justice system at a young age growing up in Inglewood.
After a few failed attempts at getting sober, a€?something clickeda€? around 2012, Harris said.
Court records show Harris has not been charged with any crimes in the past four years in Riverside or San Bernardino counties. Instead, he worked for several temp agencies over the years, mostly doing jobs that taxed his body, such as plastic injection molding, delivering machine parts and building silos.
A drug that mirrors the behavior of these mutations could prevent diabetes even in people at greatest risk for the disease.
They specifically chose to include subjects who did not have Type 2 diabetes but had significant risk factors such as being older and overweight.
Glucose is made of the sugars and starches the body digests from food to give cells fuel, and "insulin takes the sugar from the blood to the cell," according to the ADA's website.
David Altshuler, deputy director and chief academic officer at the Broad Institute and a Harvard Medical School professor, said in a statement. While these results could prove hugely significant for those at risk of developing the disease, locating a drug target is only one step in the process. More than half of these events occurred because of a lack of drug information at the time of prescribing.4Maintain drug references.
Do not store drugs with look-alike names or similar packaging in close proximity to each other in the medication storage area, exam medication storage area, exam rooms or sample closet.
All liquid oral medications prescribed or dispensed in the office should be administered using a proper measuring device.
The key concepts in all of these strategies are to simplify and to standardize your systems related to medications. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference.

Though he still feels haunted by the mistakes he made in his youth, he believes he is finally able to move in the right direction, toward a higher education, better-paying and less physically demanding work and, ultimately, a better life.
His felony record made it difficult for him to land a job that was stable and permanent, let alone one that paid well. The researchers also included low-risk subjects like "lean" non-smokers, according to The New York Times. To help ensure that the right patient receives the right medication, instruct your staff to use at least two patient-specific identifiers, such as the patient's name and date of birth, when administering medications.
It is unrealistic to expect any physician can be conversant on the tens of thousands of prescription and over-the-counter medications on the market. This encourages all physicians and staff to be vigilant and to detect and act on potential error signals, rather than dismissing them. The use of parenteral syringes to administer oral medications, a common but dangerous practice, has resulted in aspiration of the syringe tips when they are not removed. In some cases, you may be able to determine that a patient has low health literacy simply by the way he or she fills out the new patient questionnaire or other forms in your practice.
Using this article as your guide, assess how well your office is currently doing at following known safe practices.
While it does take effort, it doesn't necessarily involve a large financial investment, and it will improve the way your practice functions and the level of safety you can offer your patients.
Vaida is executive vice president for the Institute for Safe Medication Practices, based in Huntingdon Valley, Pa. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP.
Several of his prior drug-possession convictions from years ago were reclassified as misdemeanors.
He wants to be able to work a job thata€™s less physically taxing but pays enough to support his family.
They focused their analysis on a set of genes that previous studies suggested might be critical in the development or prevention of diabetes, although earlier research conflicted over whether the genes were harmful or helpful. To help decrease risk to patients, make sure that all staff members who prescribe, dispense, administer or provide patient education on medications have easy access to current drug information and other decision support resources. Physicians can model this behavior simply by asking their nurses, medical assistants and others for input and by sharing information with other team members on a regular basis.Improve your handwriting.
This assessment process should allow all team members to share information openly and honestly. Harris said he still has felonies on his record from incidents in San Bernardino and Los Angeles counties, and is working to get those reclassified as well. This article will focus on simple, low-cost strategies for safe medication use that can be incorporated into office-based practice. A 1979 study estimated that one-third of physicians' handwriting was illegible.6 Presumably little has changed over the years.
ISMP has reported on several mix-ups with PPD being given in place of vaccines and vice versa.Separate external solutions, non-drug items, testing solutions, reagents and chemicals from internal products.
All office personnel who dispense or prescribe any device (multiple daily injection devices, glucose monitoring devices, etc.) should be educated on its use.
It is possible to accomplish this assessment in approximately three minutes during the initial intake evaluation of a patient. The tool was developed by ISMP, the Medical Group Management Association and the Health Research and Educational Trust.Make it easy to learn from errors.
Written medication guidelines that outline the correct dosages, contraindications, precautions and other critical information for frequently prescribed medications can be invaluable. The FDA and ISMP in July 2006 embarked on a joint campaign to eliminate the use of potentially confusing abbreviations, symbols and dose designations in various forms of medical communication. Designate a staff member to routinely check (at least quarterly) all medications (including samples), reagents and other products that carry an expiration date and discard any that have expired.

Your staff should feel comfortable disclosing information on errors that have occurred, discussing unsafe practices and sharing external reports on medication errors. These abbreviations, symbols and dose designations have proven to be a barrier to effective communication and have resulted in significant harm to patients. The storage area should be maintained at temperatures between 57 and 84 degrees, it should not be cramped, shelves should be at eye level with labels facing forward, and the area should be well lit making it less likely the staff will misread labels.Control access to medications. Patients should be given both oral and written instructions on the use of their medications, and they or their caregivers should be asked to repeat back the information to demonstrate complete understanding. Make sure you have a system in place for reporting errors, and make it clear to your staff that errors will be considered opportunities for education, not punishment. While it may seem unnecessary, prescribers need to stress to patients the importance of getting the prescription filled and taking the medication as ordered. When errors or near misses take place, include all clinicians and non-clinical personnel in educational efforts, rather than including only those involved in the event.Look for system changes that will help prevent future errors. Four important diagnoses have a significant impact on medication selection, dosing and frequency. High-alert medications are those that have a propensity to cause serious patient harm when used in error. In addition, your practice should have strict procedures for logging, storing and monitoring drug samples. Office personnel should share past experiences and follow the literature for errors that have been reported in articles or case presentations.
They include warfarin, low-molecular-weight heparins, insulin and oral agents for diabetes, opiates and methotrexate. Many, if not all, of these drugs with similar names carry different indications for use; therefore, including the indication with the medication can reduce confusion. All medications dispensed to patients should be properly labeled with the name of the medication, strength, dose, frequency, purpose, lot number, expiration date and quantity of medication, along with the patient's name, date of dispensing and prescribing, and prescribing information. Many patients may not have insurance or their co-pays may be excessive, which may affect whether they fill their medications. The prescription pad shown in this article contains check boxes for common indication categories that can help communicate the purpose of the medication being prescribed. A current medication profile listed in a standard prominent location on each patient's chart can be an important safety measure. This should be updated at each visit and should include a reminder to ask not only about prescription drugs but also over-the-counter medications, herbal medicines, supplements and vitamins. For example, in the following prescription the drug name Avandia was incorrectly interpreted as Coumadin.INCLUDING THE INDICATIONIncluding a drug's indication on the prescription is a simple safety measure. Structure the medication list to require that the drug, dose, route, frequency and purpose be recorded for each medication, herbal or vitamin.Standardize height and weight measurements. The indication, whether hand-written or communicated via check boxes, helps pharmacists and others avoid confusion between look-alike drug names. ISMP recommends that health care professionals record information in metric units, which are commonly used in medication labeling and package inserts, as a way to standardize measurement. Orders given verbally, rather than in written form, are inherently problematic because of different dialects and accents, misinterpretations of names and strengths, etc. Electronic prescribing systems can produce computer-generated prescriptions or can electronically transmit the prescription directly to the pharmacy. The technical aspects of implementing and using an e-prescribing system are beyond the scope of this article, but they are worth investigation.

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