26.07.2015

Pregnant after ivf miscarriage

As women age, the reproductive quality of their eggs begins to decline, making it increasingly difficult for them to get pregnant naturally without IVF or IVF using donor eggs. In this article I review the the United States Center for Disease Control statistics and pregnancy success rates for women 45 years and older using IVF with their own eggs. For women 44 and older, 3.3 percent of IVF cycles using their own eggs resulted in a live birth. A woman’s age not only affects the chance for pregnancy when her own eggs are used, but also affects her risk for miscarriage. The percentage of IVF cycles that resulted in miscarriages began to increase among women in their mid?to late 30s and continued to increase with age, reaching 30 percent at age 40 and almost 58 percent among women older than 44.
The percentage of cycles that progress from transfer to pregnancy also decreases as women get older.
Numerous studies have documented the increased risk for miscarriage (pregnancy loss) and increase in infertility as women age. The graph below shows information about miscarriage rates after IVF (using own eggs) from the 2012 CDC report.
Miscarriage rates would be higher if early miscarriages (such as "chemical pregnancies") were included. Miscarriage rates for women with a history of infertility tend to be higher than for fertile women. The main reason for the increased risk for miscarriage in "older" women is due to the increase in chromosomal abnormalities (abnormal karyotype) in their eggs. Patients who have been having trouble getting pregnant are very excited when their HCG test is positive! However, like any other pregnancy, 10% of all IVF pregnancies are also destined to have medical problems.
The commonest reason for a miscarriage is a genetic problem in the embryo, which prevents it from developing properly.


If a fetal heartbeat can be seen, this means that there is a 95 % chance that the pregnancy will proceed normally.
You need to do a check scan one week after the bleeding stops, to confirm the products of conception are completely evacuated. It can be very hard to bounce back if you miscarry after IVF treatment after a miscarriage!  Lots of patients get disheartened and give up.  They lose faith in God because they feel he has been exceptionally unkind to them.
The commonest reason for a miscarriage is a genetic abnormality in the fetus, and this is Nature’s defense mechanism, to prevent the birth of an abnormal baby.
This results in lower chances for getting pregnant at all, as well as increasing the risk of miscarriage.
Note the similarity in the shape of the curve in the graph above to the one below showing the rate of chromosomal abnormalities in IVF embryos by age. The graph below shows the rate of chromosomally abnormal IVF eggs by female age (approximate and compiled from several studies). They are on top of the world that their IVF treatment has succeeded, and they look forward to cradling their baby in their arms in a few months.
This is a random event, and the risk of recurrence is low, which means patients can be reassured that their chances of having a healthy pregnancy for the future are actually quite good! Others blame themselves for the miscarriage and their self-esteem takes a further battering.
They feel that if they can carry a pregnancy to 8 weeks, they can carry one to 8 months as well – and the fact that their embryo did implant gives them a confidence boost!
Tagged in: blighted ovum, in vitro fertilization, IVF, miscarriage, missed abortion, threatened miscarriage. I suffered 2 miscarriages one at 17 weeks (in 2012) after I conceived through IUI and one in 7 weeks after I conceived through IVF (in 2014) with my own eggs.
Aniruddha Malpani is an IVF specialist with a brilliant career with numerous awards, educational distinctions and prizes.


HFEA reduces maximum number of embryos transferred in single IVF treatment from three to two [press release].
However, older women, and those with poor ovarian reserve, have an increased risk of having a repeat miscarriage, because their eggs have more genetically abnormalities, which we still cannot test for.
This is why these problems are now better treated with medical therapy.  These pregnancies can be terminated medically with mifegest (anti-progestational agent) and misoprostol ( a prostaglandin).
After that I tried 2 IVF’s with donor eggs, but each time my pregnancy could not progress beyond 5 weeks.
High serum oestradiol levels in fresh IVF cycles do not impair implantation and pregnancy rates in subsequent FET cycles.
Birthweight of singletons after assisted reproduction is higher after single- than after double-embryo transfer. Increased risk of preterm birth in singleton pregnancies after blastocyst versus Day 3 embryo transfer: Canadian ART Register (CARTR) analysis. New Belgian legislation regarding the limitation of transferable embryos in in vitro fertilization cycles does not significantly influence the pregnancy rate but reduces the multiple pregnancy rate in a threefold way in the Leuven University Fertility Center.
This means that even though the woman is pregnant, and the pregnancy tests are all positive, there is no baby.
If some of the pregnancy has already been pushed out by the contractions, this is called an incomplete abortion. Many ill-informed relatives and friends also add to their misery by telling them that it was their lack of taking appropriate precautions; or their excessive levels of “stress”, which caused them to lose their pregnancy.



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