10.07.2014

Ivf at age 40

At age 40 and above women have reduced fertility potential as compared to that seen in younger women.
The charts below illustrate the rate of live births per embryo transfer procedure by the age of the recipient of the embryos. Although these age and fertility statistics are specifically about IVF success, there is a similar loss in fertility potential with aging in the general "normal fertile" population. The graphs below are from the 2012 ART Success Rates report published by the CDC, Centers for Disease Control and Prevention, a US government agency.
Another point shown here is that there not a substantial decline in success by age of the recipient woman with donor egg IVF. The national summary (as well as clinic specific results) of IVF success rates for cycles done in years 1995 through 2012 are posted on the CDC website.


All clinics have some upper age limit after which they will not perform in vitro fertilization with the woman's own eggs. High quality IVF results in better embryo quality which leads to better chances for successful outcomes - at any age. Most IVF centers are willing to attempt IVF using the female partner's eggs until about age 44, after which the couple would be offered egg donation as the only realistic advanced fertility treatment. With treatments such as IVF, the issue that holds back success potential is both egg quality and egg quantity. With IVF treatment we hope to get multiple embryos so we can choose the best ones from a group for transfer back to the uterus. The rate of chromosomal abnormalities in eggs (and therefore also in embryos) increases significantly with advancing female age.


However, when going through a fertility treatment such as IVF, the quantity of eggs remaining influences response to ovarian stimulating medications. This report was generated from national data from hundreds of clinics and well over 100,000 IVF cycles.
The report summarizes national data from hundreds of clinics and many thousands of IVF treatments.
Egg quality translates over to embryo quality - which is by far the most important factor determining if IVF works.



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