19.03.2015

Dhea for fertility over 40

Around the age of menopause, women not only lack estrogens but also androgens and some estrogens originating from adrenal DHEA. Dehydroepiandrosterone, or DHEA, is a natural steroid hormone produced abundantly by the adrenal gland. Although the research still remains preliminary, these findings hold great promise for the future of infertility. The probable reason for the decrease in chance of conception and the increase in miscarriage with age is the increased number of abnormal eggs that are present (Figure 3). There are a variety of treatments for infertility, but the options become more limited as ovarian function wanes. Studies of women with abnormal ovarian reserve testing show a dramatic decrease in fertility regardless of age. We are currently performing a clinical trials on women with diminished ovarian reserve using DHEA. Although egg donation is a highly effective therapy, earlier discovery of problems will often allow couples to have more options for therapy to choose from. The Virginia Center for Reproductive Medicine (VCRM), is a state of the art Fertility Center located in the Greater Washington, D.C and Northern Virginia area. Elena and her new husband have been to a fertility clinic and were already confronted with the idea of considering entering the egg donation program. No wonder Elena needed to talk to someone who has nothing but eggs on her mind for the most part of the day (by the way, you can also talk to me, once a week I am available to chat on Skype). During the months that I was taking DHEA, my skin looked better (verified by objective third parties who had not seen me in a long time) and several wrinkles had disappeared from my face.


Disclaimer: This information is for educational purposes only, and is in no way intended to be personal medical advice. Surgical solutions can be appropriate for certain problems in some patients, but require recovery time as well as time to conceive after that.
In a study publish in the October, 2001 issue of Fertility and Sterility, the basal FSH measurements of nearly 10, 000 patients was evaluated. Fortunately, women with diminished ovarian reserve still have good options for becoming parents, which include egg donation and adoption. DHEA is a weak androgen (male hormone) that is available as a supplement in most Vitamin stores. When combined with fertility drugs (gonadotropins or clomiphene), it can be an effective therapy. A comparison of clinic success rates may not be meaningful because patient medical characteristics and treatment approaches may vary form clinic to clinic.
In otherwise healthy women, who have no other problems but their advanced reproductive age, DHEA is the first option to consider. Conservative hormonal therapies (such as clomiphene citrate or gonadotropins combined with intrauterine insemination) can be effective for appropriately selected patients under 40, but are much less effective in women over 40 years old.
In vitro fertilization is the most effective therapy for women using their own eggs at any age.
There are currently only a very small number of papers, mostly from one group, detailing their experience with DHEA.
A discussion of your concerns with your gynecologist is a good place to start, and a prompt referral to a Fertility Specialist can make all the difference in your chances at having a child.


Unfortunately, there are few, if any, outward signs of decline in reproductive potential for most women.
Very high numbers of small follicles suggests a tendency to over respond to hormonal stimulation, and this is a common finding in women with polycystic ovaries (PCOS).
It seems that DHEA, when taken for at least 2-3 months, may increase fertility potential in some patients. If the FSH is not in the correct range, the test is abnormal and the live birth rate for these patients is extremely poor. Recent studies, albeit very few and with small numbers, suggest however that some women, even those with elevated FSH who are now being told to pursue donor egg or adoption, may have still a chance at conceiving using their own eggs after using DHEA (see below).
The literature is indeed very scant, and we do not know currently whether DHEA provides ANY benefits.
This may represent a quantum shift in the field of reproductive medicine, and would overturn some established dogma. We believe DHEA MAY hold some promise for SOME patients with diminished ovarian reserve and high FSH and low AMH. It has been estimated that only 10-30% of women over 40 are able to become pregnant on their own. At VCRM, we are undergoing clinical studies to investigate this novel concept further, and try to identify the groups that are likley to benefit from DHEA.



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Comments to «Dhea for fertility over 40»

  1. Bakinskiy_Avtos writes:
    And avoiding meals that may set the center.
  2. 099 writes:
    About 3 months, i believed i was pregnant for awhile.
  3. Roni_013 writes:
    You are attempting to conceive, the.