Prof John Betteridge, London, discusses the evolution of diabetes therapy, the epidemic rise in diabetes, current and emerging diabetes therapies. In GPRD data, current use of sulphonylureas only (with active or inactive metabolites) was associated with an increased risk of hypoglycaemic events, as compared with current use of metformin. Recent outcome trials of novel antidiabetic drugs shed new light on why diabetes patients develop heart disease.
Out of 18 biomarkers, Lp-PLA2 and adiponectin were independently associated with a decreased risk for T2DM. In females with gestational diabetes, the future risk of developing type 2 diabetes depends on certain pregnancy-related and maternal factors that could be used for postnatal counselling.
EMPA-REG OUTCOME trial shows that empagliflozin reduces microvascular outcomes and progression of kidney disease in T2DM patients at high CV risk.
ADA 2016 In T2DM patients at high CV risk, liraglutide on top of standard therapy was associated with lower rates of CV events and mortality, compared with placebo in the LEADER outcome trial.

ADA 2016 New empagliflozin data show that reduced risk for cardiovascular death was consistent across age groups in adults with type 2 diabetes.
ADA 2016 Two phase 3 studies of oral SGLT-2 inhibitor ertugliflozin met primary endpoints, showing significantly greater A1c reductions than placebo, alone or in combination with sitagliptin. The earlier young men start with this tightly controlled intensive insulin therapy; the better their chances of not suffering from erectile dysfunction ( one of the major causes of which is diabetes). This development is important because as the incidence of diabetes rises, it also increases the number of men who suffer from erectile dysfunction or impotence.
Diabetes and Erectile Dysfunction Erectile dysfunction (ED) is a common problem amongst men who have diabetes affecting 35-75% of male diabetics. A lot of young men who suffer from this type of diabetes are ignorant of the effect their condition can have on their sexual health later on in life. Always seek the advice of your physician, nurse or other qualified health care provider before you undergo any treatment or for answers to any questions you may have regarding a medical condition.

If you suffer from this type of diabetes, then I suggest you talk to your doctor about implementing intensive insulin therapy as soon as possible. Nothing contained in the Service is intended to be or is to be used for medical advice, diagnosis or treatment. Further treatment such as surgery and vacuum devices may also have a role to play in some specific cases.
The pump, which may be battery or hand pump operated, creates a vacuum that will draw blood into the penis making it erect.

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