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Endogenous bacteria resident in our gut constantly interact with our immune system, starting from our birth, when our gastro-intestinal tract is rapidly colonised by bacteria coming from the maternal uro-genital tract and the enviroment. Even if progress has recently been made in analyzing possible mechanisms involved in this exchange of information, a lot of work remains to be done.
Acquired or induced tolerance refers to the immune system's adaptation to external antigens. The interpretation of the constant dialogue between bacteria and our body, mediated by the immune system, requires deep investigations. Ingested probiotics participate in this cascade of events by modulating mucosal receptors triggering signaling cascades that ultimately activate underlying immune cells in the lamina propria. The opportunity to pre-screen potential probiotic strains on the basis of the immunological profile they can induce in the host, is a very useful tool to orientate further applications of probiotics. Ignazio Castagliuolo, Francesca Galeazzi, Susanna Ferrari, Marina Elli, Deborah Tormen, Paola Brun, Giacomo C.
Sandra Voltan, Diego Martines, Marina Elli, Paola Brun, Stefano Longo, Andrea Porzionato, Raffaele DeCaro, Giorgio Palù, Giacomo C.
First of all, our guts are the heart of our immune systems so it’s very important to keep bacteria in balance to keep our immune systems strong. Kefir is a fermented milk product that originated centuries ago in the Caucasus mountains, and is now enjoyed by many different cultures worldwide, particularly in Europe and Asia.
Besides containing highly beneficial bacteria and yeasts, kefir is a rich source of many different vitamins, minerals and essential amino acids that promote healing and repair, as well as general health maintenance. YOGURT: The beneficial bacteria found in yogurt help keep the digestive tract clean and provide food for the friendly bacteria found in a healthy gut. Kefir has more strains of beneficial bacteria and good yeasts; over 50 in homemade kefir, while yogurt only has 7 to 10. I’ve also read that even lactose-intolerant individuals can tolerate kefir as it soothes the tummy because the “good” bacteria have digested the lactose in the milk.
I usually drink my kefir (always organic) straight up but I also use it in my protein shakes and make delicious salad dressings with it. I’m so happy that I gave kefir a chance because my diet lacks probiotics and they are essential to our immune system. This entry was posted in Natural News and tagged bacteria, Calcium, digestion, digestive tract, fermented, Health, Immune system, intestinal tract, Kefir, lactose, Probiotic, protein, Vitamin B, Vitamin K2, yeast, yogurt on March 30, 2014 by Bunny. In your digestive system there is a community of flora, or naturally-occurring bacteria, that it's important to keep in balance. An intestinal mucus layer lines the digestive tract and acts as a barrier and protection to keep bad bacteria out of your body.
Probiotics help stimulate the production of the protective mucus layer and can also line the mucus layer to add an extra level of defense. Immune cells in your intestinal immune system are constantly on guard, testing all the things that enter your body to decide whether they are good (let them in) or bad (keep them out).
The ubiquitous use of prescribed antibiotics, over the counter drugs and our feedlot animals impair beneficial bacteria necessary for a healthy digestive system. Beneficial bacteria, known as friendly bacteria or probiotics (for life), lives in the gut in massive amounts.
The Lactobacillus family contains many types of friendly bacteria that help the body’s resiliency to illness and disease. Bifidobacterium is found mainly in the large intestine and also in the lower part of the small intestine. Due to our lifestyles, the body constantly fights the invasion of bad bacteria and toxins that lead to chronic illness and disease. A study was conducted in Sweden in a company examining the effect of probiotics on their ability to improve work-place health by reducing short term sick-leave caused by respiratory or gastrointestinal infections.
Everyone is exposed to toxins and bacteria on a daily basis so it is not only prudent, but necessary to take probiotics for preventive measures. Contrary to popular belief, consuming frozen yogurt, fruity dairy yogurts, yogurt covered raisins or nuts, does not provide any protection.
You may wish to consult an integrative health professional familiar with the benefits of friendly bacteria. As always, a wholistic lifestyle that includes a good multi-vitamin, healthy eating, exercise, stress management, rest and moderation of behavior (temperance) are important.
The definition of the World Health Organization (WHO) for probiotics is any viable microorganism that when ingested in sufficient quantities will have health benefits. Probiotics are simple, they are good bacteria needed to crowd out bad bacteria, especially in our digestive tracts which have millions of bacteria. Most commercial yogurts have probiotics in them, check labels and make sure they have probiotics. Probiotics produce cellular messages that calm harmful inflammation in every part of the body.
Probiotics can ease inflammation of the large intestine in cases of colitis and help control cramps and diarrhea. Prebiotics are non-digestible ingredients found in foods like soy and bananas to promote growth of healthy bacteria in the digestive system, they act as fuel for probiotics. The combination of prebiotics with probiotics is defined as symbiotic and provide benefits by improving the survival and implantation of live microbial dietary supplements in the gastrointestinal system. There is so much more to this time of year than the hustle and bustle, the crowds, and the stress. Disclaimer: All content on this website is for informational purposes only and should not be considered to be a specific diagnosis or treatment plan for any individual situation.
It is commonly suggested that probiotics must stick and multiply in the gut to be effective. You could take probiotics day after day, year after year and if you stop, you will see that specific probiotic strain level decline and disappear. The only way to directly influence the level of your specific strain of gut flora is to take the same exact strain probiotic – L.
I use a blend of 15 Probiotic from a supplier which does wonders for making a great tasting yogurt but they don't list the strains. Learned the probiotics specific strain would have to match those native to my gut - which appears to be a low probability. Even if one were to take a pharmaceutical line probiotics with strains that have been studied and shown to be effective - does it need to be taken forever? A capsule of Probiotic Immunity contains 1 billion each of 10 different… (New Chapter Inc. One of the most important natural kinds of acquired tolerance occurs during pregnancy, where the fetus and the placenta must be tolerated by the maternal immune system.
The evaluation of the ability of probiotics to trigger immunological responses in murine models and in humans represents one of the service that AAT can perform, together with its scientific partners. Sturniolo, Lorenzo Morelli, Diego Martines (2007) Aggregating phenotype in Lactobacillus crispatus determines intestinal colonization and TLR2 and TLR4 modulation in murine colonic mucosa. Sturniolo, Lorenzo Morelli, Ignazio Castagliuolo (2008) H2O2 as a signal transducing molecule in Lactobacillus crispatus M247 induced PPAR? With a good immune system, you have the best chance to fight off illness without antibiotics or medicines. It is slightly sour and carbonated due to the fermentation activity of the symbiotic colony of bacteria and yeast that make up the “grains” used to culture the milk (not actual grains, but a grain-like matrix of proteins, lipids, and sugars that feed the microbes). The various types of beneficial microbiota contained in kefir make it one of the most potent probiotic foods available. Kefir bacteria act like a SWAT team entering into the colon and attaching themselves to the colon, pushing away other harmful substances.
There are three different ways that the digestive system and probiotics help build your immunity.

They also help out-compete the bad bacteria that may cause harm, and they secrete chemicals that kill off some bad bacteria. Probiotics help stimulate and exercise the immune cells by going through a sampling and screening process that acts just like a fire drill.
The gut is responsible for digesting foods aided by several organs, specific enzymes, good bacteria and nutrients.
Lactobacillus acidophilus is present mainly in the small intestine and works at lowering cholesterol levels, LDL levels and killing candida yeasts.
These friendly bacteria prevent toxicity that comes from nitrites in food, helps detoxify bile and assists in the management of some liver conditions and illnesses.
Because friendly bacteria have such powerful ability to rid the body of toxicity and unfriendly organisms, it is necessary to consume them on a regular basis.
Two weeks of supplement probiotics or enjoying yogurt will help with almost all digestive inflammation conditions.
Use of this website and the information contained herein does not create a doctor-patient relationship. When you look at two bottles and you see one has a million colony forming units and the other bottle has a billion colony forming units, the bottle that has a billion is not better. Direct to consume lines do not often contain the label ingredients, nor do they come close to containing the listed label dose per serving.
Because as you said - once you stop, you will see that specific probiotic strain level decline and disappear? As you’ll discover in this article, these bacteria do much more than simply keep things running smoothly in our digestive tract.And if you’re among those who think that the health benefits of probiotics have been overrated, keep scrolling to find out what happens if the delicate gut ecology is disrupted. Pioneer bacteria modulate gene expression in intestinal epithelial cells of the newborn, predisposing the environment to the subsequent bacterial colonisation.
Moreover, the establishment of a resident microbiota in our gastro-intestinal tract since birth contributes significantly to this mechanism, in order to create a balance between the ability of our immune system to recognise exogenous pathogens and, at the same time, to tolerate the presence and activity of endogenous beneficial and potentially harmful bacteria.
Beneficial effect of Lactobacillus crispatus on experimentally induced colitis in mice: effect of different phenotypes. It is a good source of biotin, a B vitamin that HELPS the body assimilate other B vitamins. So while yogurt may contain a handful of different strains of bacteria, kefir may contain many more than that.
So, probiotics help prepare your immune cells to fight off any bad bacteria that come their way! The digestive process feeds the cells and provides energy for life, however the average American diet assaults the digestive processes with toxins that come from our foods, water and air.
Ten out of 94 workers using the probiotic took sick time during the study compared to 23 in the placebo group.
Regular use will improve your digestive health and resistance to infections and bad bacteria. Always consult with your own doctor in connection with any questions or issues you may have regarding your own health or the health of others. A number of studies have shown that probiotics do not become established members of your gut ecosystem and when you stop taking them, their numbers dwindle quickly. We can detect the probiotic that you are taking, when you are taking it, but the native colonies will remain mostly unaffected. The problem is that we are not yet able to test your specific strain and customize a probiotic blend that is specific to your native gut flora. In studies we have seen dead probiotics, with no biological activity, still have a positive effect on health. The better probiotic is the one that contains the strain that has been shown in studies to be effective.
These are manufactured to be at label dose at the time of manufacture, and not the time that you take them. The complete proteins in kefir are already partially digested, and are therefore more easily utilized by the body. It also boasts more protein, B vitamins and more relaxing amino acid tryptophan than yogurt.
Furthermore, none of the 26 workers using the probiotics lost any time due to illness compared to nine out of 27 in the placebo group.
This article will illuminate the conditions and situations where probiotics are claimed to be beneficial, for inflammatory bowel syndrome and gastrointestinal conditions in general. We are simply not there yet, but this is what is coming and WHAT a game changer it will be. They help to tune and regulate the immune system by interacting with immune cells in the gut.
We need to look to the studies to see which strains have been studied and shown to be effective and use these.
Rotate the strains you are using every three months and take a few months off a year (this is maintenance). The amazing gut ecologyDid you know about 100,000,000,000,000 (100 trillion) microorganisms think of your gut as ‘home sweet home’?
Like many other dairy products, kefir is a great source of minerals like calcium and magnesium, as well as phosphorus, which helps the body utilize carbohydrates, fats and proteins for cell growth, maintenance and energy. They clean house and strengthen the gut, making it harder for pathogens to dominate and parasites to exist. The benefits of probiotics are far way ahead of the gut, they improve modification of emotional states and improvement of neurological functioning. When we are able to offer the exact strains of your native gut flora in a probiotic, this is going to going to be a magic pill. They manufacture these at higher than label dose, compensating for die off of active cultures while sitting on the shelf or at home. This is why the probiotic bottle MUST list the strain, otherwise they don’t even know what is in it. There is a small percentage of children that had probiotic-related infections in clinical trials, pay attention to effects in yourself.
Specialized health stores carry a good variety, many common yogurts are improperly labeled.
Just to give you a visual idea, if you laid one dollar bills end-to-end from the earth to the sun and back, you would require way more than one trillion bills!
Now, do that a 100 times more to get a (vague) idea of how much 100 trillion is… Sounds like we’re more bacteria than human!In fact, our gastrointestinal system is home to more than 400 different species of bacteria – colonization begins right after birth and is more effective if the baby is born via the vaginal route.
These bacteria which prevent pathogens from multiplying in the gut, make up more than 75% of our immune system.Health benefits of probiotics you’re probably unaware of.
Users are instructed to take two capsules each day, preferably one in the morning and one in the evening, on an empty stomach.
But senior vice president of marketing Brian Colin says that the company cannot legally claim to prevent or treat any disease, including the cold and flu. Research suggests that when the gut is inflamed – this can occur if your diet is packed with processed ‘foods’ such as vegetable seed oils, sugar, refined carbs, gluten, soy and so on – it promotes the release of inflammatory ?cytokines in the blood. Companies "are taking evidence from animal studies and stretching their claims," he says.Still, Forsythe sees some room for hope that the right probiotic could make the cold and flu season a little less miserable.
There’s something going wrong – we need to be on the alert!’  This alert signal stresses you out.
Plus these inflammatory cytokines are able to cross the blood-brain barrier where they induce ?inflammation in the brain, creating symptoms of depression. And an April 2011 study in the European Journal of Clinical Nutrition found a Lactobacillus probiotic seemed to improve the immune system's response following a flu vaccination.Dr.

Sonia Michail, a pediatric gastroenterologist at Children's Hospital Los Angeles, says the basic idea behind so-called immunity-boosting probiotics makes sense. The researchers found that, compared to the control group, subjects given the probiotics paid more attention to the positive information than to the negative information. As she explains, the gut is a major front in the immune system's war against pathogens, and the immune cells there must respond to the resident bacteria. If helpful bacteria can activate immune cells in the gut, the disease fighters will spread throughout the body.But according to Michail, studies suggest that, for unknown reasons, only some people a€” perhaps as few as 1 in 30 a€” could hope to avoid a cold by taking probiotics.
And, she adds, the evidence for even this modest benefit "is far from robust."Forsythe says that probiotics are generally safe and might be worth a try, if only for the extra peace of mind. Probiotics can help you shed body fat.Did you know that weight gain has been linked to the composition of the gut flora? And that, compared to their leaner counterparts, obese individuals have a less diverse gut flora? In fact, it appears that obese individuals have 90% less bacteroidetes and 20% more firmicutes than lean individuals. Well, firmicutes are better than bacteroidetes at extracting calories from food and storing them as fat.
In other words, the more firmicutes you have in your gut, the more of your food will be converted into fat.Moreover, as mentioned earlier, an unhealthy gut can lead to brain inflammation – inflammatory cytokines have been found to block leptin receptor sites, gradually making the body “leptin resistant”.
Since the hormone leptin induces satiety and tells the brain to burn body fat for energy, leptin resistance makes it harder to lose weight by making you hungrier and making it harder for your body to burn fat.Research findings Japanese researchers gave a group of 210 overweight women 7 ounces of fermented milk per day for 12 weeks. The researchers found that, compared to the control group, those who received the ‘spiked’ drink lost 8 to 9% of their visceral fat.
This type of fat surrounds the organs and can cause numerous health issues when present in excess.
These women also lost 1 to 3% of their belly fat.In another study, obese individuals were given either a placebo or a probiotic containing Lactobacillus rhamnosusfor 12 weeks. This constituted the weight loss plan which was followed by a 12-week weight maintenance plan. No significant weight loss changes were seen between the men in the placebo and treatment group.
What’s interesting is that the women who received the probiotic continued to lose body fat after the maintenance phase whereas the control group gained weight.In a lab study, scientists transferred the gut flora of obese mice into the guts of skinny ones.
These skinny mice immediately started eating excessively and gradually became obese.Behind the linkProbiotics may help improve metabolism while increasing adiponectin, an anti-inflammatory signal that enhances the body’s ability to burn belly fat.
Adiponectin also regulates lipid and glucose metabolism.Probiotics can help decrease intestinal permeability thus keeping the intestinal barrier strong. Although you need to have more than one of these conditions to be diagnosed with the metabolic syndrome, having any of them predispose you to serious health issues. And the more of these conditions occur together, the greater your risks for adverse health issues. Research suggests that probiotics can help you slip out of this risky web!Research findings The probiotic strain Bifidobacterium (B.) animalis subsp.
Probiotics can enhance heart health.A crucial strategy that can considerably help reduce our risks of dying from heart disease lies within our own intestinal tracts. Ensuring that beneficial bacteria are thriving in your gut could protect you from various heart conditions.Research findings Congestive heart failure In a small study published this year, researchers gave 20 patients suffering from congestive heart failure supplements containing the probiotic S. The probiotic group experienced improved heart function, reduced inflammatory markers and a reduction in cholesterol levels. These effects were not seen in the placebo group.Blood pressure A review of nine studies showed that, compared to the control groups, subjects who received a probiotic experienced reduction in blood pressure. The probiotic group experienced a 9% reduction in total cholesterol while LDL levels fell by almost 12%. What’s interesting is that these patients also had an 8% reduction in apolipoprotein B-100, a marker of LDL particle number and a known risk factor for cardiovascular disease. That’s not all; the intestinal immune system produces more antibodies than the rest of the body put together! So it’s not hard to understand that if your gut flora is unhealthy, your immune system will suffer.Research findings Bowel inflammation is a major culprit behind colon cancer, the third most common cancer in the world. Probiotics hold promise for skin issues.Did you know that your skin is the window to your gut and liver? Stokes and Pillsbury directly linked skin inflammation to changes in the microbes and bacteria present in the gut. Research shows that a damaged gut can:Upset hormonal balance thus increasing oil production in your skin.Reduce the skin’s natural production of antimicrobial peptides, resulting in worsening skin inflammation or red and swollen pimples that hurt like crazy! Not only does this cause inflammation but insufficient ?gastric acid also mean that fewer nutrients (including ?antioxidants that can tone down inflammation) will reach your skin cells.
This was replicated by Russian and Italian scientists who showed that acne and rosacea patients who received probiotics experienced better symptom clearance compared to the control group. Moreover, acne sufferers who consumed a Lactobacillus-containing beverage for 12 weeks had fewer acne lesions and produced less sebum.Probiotics can tone down eczema Although genes play a major role in the development of eczema (also known as atopic dermatitis), studies suggest that probiotics can help prevent the condition especially when given at an early age. In fact, a review of 21 studies involving 11,000 children at risk of developing eczema showed that supplementing with Lactobacillus rhapsodic GG or Lactobacillus rhamnosus strain HN001 slashed kids’ risk of developing eczema in half compared to those taking a placebo. Probiotics can improve oral health. What is your ‘go-to’ product to combat oral issues? Well, not only do these products not work as advertised but they can actually worsen your oral issues. Don’t be; after all your digestive tract starts with your mouth so it’s only logical that good bacteria can affect your oral health. In fact, unbalanced bacterial flora in the mouth has been linked to increased risks of cavity formation, gingival inflammation and bad breath.Research findings Probiotics and dental caries Scientists found that a probiotic mouth rinse was as effective as chlorhexidine (the gold standard mouthwash with antibacterial properties) in decreasing plaque accumulation. If left unchecked, gingivitis can lead to a more serious infection known as periodontitis, a progressive, destructive ailment that affects all supporting tissues of the teeth, including the alveolar bone. When subjects were given probiotics infused into a mouth rinse, lozenge, chewing gum or tablet for four weeks, they experienced a significant improvement in bad breath. Researchers utilized either Streptococcus salivarius K12 or Lactobacillus salivarius WB21.Behind the linkStudies show that the friendly bugs in your ?mouth – yeah, that’s not a very nice picture – produce hydrogen peroxide as well as other antimicrobial ?substances that suppress the growth of harmful bacteria. Probiotics may play a role in fertility.While probiotics are in no way a ‘cure’ for fertility issues, supplementation with Lactobacillus rhamnosus GG, Bifidobacterium bifidum, Lactococcus lactis, and Bifido breve have been found to be valuable in enhancing fertility and keeping pregnancy complications at bay.
She is currently doing her MS in Nutrition & Health Promotion at Mississippi State University with the aim of helping others achieve optimal health with real foods. Any health concern or condition should be addressed by a doctor or other appropriate health care professional.
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