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This is kind of like recreating the paleo diet with the organisms present on the food they would have been consuming,” he said. The problem with the approach has been that many of these organisms proved delicate.“There were quite a few challenges,” Bakal said.
The marketers of spore-forming probiotics that also target foods and supplements, such as Ganeden Biotech, Sabinsa Corp. But that stability can be a two-edged sword, Bakal said.“Most food plants are trying to get rid of spores because they are the thing that is so difficult to kill. The new strain is part of the development of the probiotic space from a shotgun approach (just get a lot of CFUs in there) to a method of drilling down to the specific strain level to prove benefits, he said.“Originally it was you just call it a probiotic and that was enough.


Then there was sort of a cold war in the probiotic space with everyone claiming higher and higher colony forming unit figures. These studies can be quite expensive, and you hope get lucky to get into an NIH study or a university study,” Bakal said.“If you look at the science claimed by some other companies, a lot of those are studies they didn’t do themselves. We have data on immune response and on general gut health, and one of things we are trying to do is to excite interest on the part of potential research partners,” he said.



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