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You must have JavaScript enabled in your browser to utilize the functionality of this website. Pancreatin is a mixture of several digestive enzymes produced by the exocrine cells of the pancreas.
Enzymes are naturally occurring substances that are found in every living thing and are essential for life. There are three groups of enzymes that operate our bodies:  Digestive enzymes break down carbohydrates, fat, and protein from our diet.
Cancer cells are aware that the body’s immune system is capable of searching them out and destroying them because they’re different.
One form of cancer whose diagnosis is often considered a death sentence is pancreatic cancer.  According to the American Cancer Society, the one-year survival rate is approximately 20 percent, and the five-year rate is only 4 percent.
The pancreas, located directly behind the lower part of the stomach, is a vital organ secreting various digestive enzymes and hormones (e.g. Factors that have been associated with an increased risk of pancreatic cancer include smoking, obesity, exposure to certain chemicals, chronic pancreatitis, genetic mutations and even type 2 diabetes. One of the reasons why pancreatic cancer is fatal is because it has already spread by the time it is diagnosed. November is Pancreatic Cancer Awareness Month, with a focus on funding further research and education. Pancreatic Cancer is one the deadliest cancers because it usually remains undetected until it reaches an advanced stage, at which point it is often too late to cure.
It is a type of cancer that affects around 8,000 people in Britain a year - two of its most famous faces are Steve Jobs and Patrick Swayze, both of whom died from the disease. However most people aren't entirely sure what their pancreas even does, let alone be on the lookout for symptoms. Dr Paul Zollinger-Read, HuffPost UK blogger and chief medical officer for Bupa, explains: "Your pancreas is a part of your digestive system that produces digestive juices. Nick Maisey, consultant oncologist at London Bridge Hospital says: "It is very common that patients have incurable ‘metastatic’ disease (ie secondaries) already by the time the diagnosis is established, because the symptoms can often be very vague, eg weight loss, loss of appetite, mild abdominal pain.
More research needs to be done to draw conclusions about how your lifestyle can affect the health of your pancreas - at present there is no solid evidence.
Although both doctors agree that it's not as simple as saying 'Eat x,y and z and you'll ward off pancreatic cancer', The Food Doctor nutritionist Alice Mackintosh says there are foods you can eat to support your pancreas regardless. Perhaps the pancreas just doesn't get as much of the limelight as the other organs, but hopefully awareness months will help to change that. It isn't just cancer that we need to be aware of when protecting our pancreas - heavy drinking and gallstones can lead to pancreatitis, where the organ is inflamed.
She adds as a final thought: "Another fundamental role of the pancreas is to secrete digestive enzymes which break down food in the digestive system. For more information and support on dealing with pancreatic cancer, visit Pancreatic Cancer UK or call 020 3535 7099.
In the early 1990s one of my chiropractor clients asked me to formulate a proteolytic enzymes formula in capsule form.
In the late 1990s a friend of mine had a microscope and display system that allowed live blood analysis. One of my clients told me the story about two old men who loved to play golf but could hardly walk due to arthritis. A German health practitioner friend of mine told a client of his who was having all of his wisdom teeth removed to take 100 capsules of Prolyt daily after the surgery. The enzyme chymotrypsin, another pancreatic enzyme, also cuts the larger protein chain but at different sites from where trypsin cuts. Bromelain is a mixture of proteolytic enzymes extracted from pineapple that digest proteins. It contains chemicals that when taken between meals might interfere with the growth of tumor cells and slow blood clotting. One study suggested that a combination of bromelain, rutosid (a bioflavonoid), and trypsin worked as well as nonsteroidal anti-inflammatory drugs, which are commonly used pain relievers, for reducing knee pain from osteoarthritis. There are studies that show bromelain may reduce swelling, bruising, healing time, and pain after surgery and physical injuries. Turmeric extract (95% curcuminoids) contains three main chemical compounds – curcumin, demethoxycurcumin, and bisdemethoxycurcumin – collectively known as curcuminoids. Studies have reported that curcumin and turmeric protect the liver against several toxicants both in vitro and in vivo. Quercetin (a bioflavonoid and known Nrf2 activator) has been shown to have powerful anti-inflammatory effects, and may be helpful to persons suffering from allergic reactions and from swelling due to injury.
Grape Seed Extract provides a highly bioavailable bioflavonoid complex containing oligomeric proanthocyanidins (OPC)  and functions as a powerful Nrf2 activator. We at HPDI believe Prolyt proteolytic enzymes formula is among the finest digestive enzymes products available today.
DIRECTIONS: When taking Prolyt as a digestive aid please take up to four capsules at a time with food.
This mixture is used to treat conditions in which pancreatic secretions are deficient, such as surgical pancreatectomy, pancreatitis and cystic fibrosis. Each enzyme has a different job, and, as of the present date, researchers have identified over three thousand different enzymes in human beings.


Amylases aid in the digestion of carbohydrates, lipases break down fats, and proteases break down proteins. This is true because the immune system is able to distinguish between that which is self and that which is foreign. It is the twelfth most common cancer worldwide, with around 338,000 new cases diagnosed in 20121.
Although not typically associated with pancreatic cancer, a sudden occurrence of jaundice, abdominal pain, changes in bowel habits associated with loss of appetite and weight may require further evaluation. A key mechanism that cancer cells use to spread in the body involves the destruction of collagen and connective tissue surrounding cancer cells. Since at the time of diagnosis pancreatic cancer is often inoperable and no proven cure is available, our research results are of the utmost importance. Pancreatic cancer is caused by an abnormal and uncontrolled growth of cells in your pancreas. Dr Maisey says that some believe in a link between 'higher risk diets' - so those that contain a lot of sugar and processed meats such as sausages and bacon - but there isn't proof. It’s primary role is to secrete insulin, a crucially important hormone that controls blood sugar levels and in so doing regulates energy levels and a whole host of other tightly controlled reactions in the body. As Alice says, the pancreas plays a huge role in how much energy we have as well as how efficiently our digestive systems run. It is best described as a full strength proteolytic enzymes formula with synergistic bioflavonoids. Several years ago when I became aware that most of the papayas grown in the world contained genetically modified organisms, I removed the papain and replaced it with curcuminoids from turmeric. While bromelain is often blended with lactose to obtain a reduced standard strength, Prolyt contains the near full-strength proteolytic enzymes extracted naturally from the fruit.
This system enabled one to take a blood sample, put it on a slide, and view it on a TV monitor. He said once a week these men would buy a bottle of Prolyt, take a handful of the capsules, and proceed to the golf course out of pain long enough to play golf for the day.
His client did it and he found that he not only controlled his pain, but he healed rapidly in less than a week. The large protein molecule is actually a chain of smaller units called amino acids which are linked, end to end, in chains of hundreds. Chymotrypsin makes its cut at positions along the protein chain that contain very large amino acids such as phenylalanine, tyrosine and tryptophan. The Scottish embryologist, John Beard, who worked at the University of Edinburgh at the turn of the century, first proposed in 1906 that pancreatic proteolytic enzymes, in addition to their well-known digestive function, represent the body’s main defense against cancer.
I have collected a number of reports from that time in the major medical journals documenting tumor regression and long-term survival in patients treated with enzyme therapy. My research advisor at the time supported and directed my early work, and later supported me during my formal immunology fellowship. Beard believed enzymes had to be injected to prevent destruction by hydrochloric acid in the stomach. In addition, bromelain has been used in conditions such as 1) surgeries and injuries (including sports injuries), 2) sinusitis, 3) poor digestion, 4) inflammation, 5) infection, and 6) osteoarthritis.
NSAIDs include ibuprofen (Advil or Motrin), naproxen (Aleve), and diclofenac (Voltaren), among others.
It is often used to reduce inflammation from with tendinitis, sprains and strains, and other minor muscle injuries.
Curcuminoids have been shown to be Nrf2 transcription factor activators that turn on the production of the body’s own protective enzymes (such as SOD, catalase, and glutathione peroxidase). Quercetin also is known to reduce viral activity and may be helpful with chronic viral syndromes. OPCs are extremely powerful antioxidants (20 times more powerful than vitamin C in vitro), potent anti-inflammatories, and collagen strengtheners. It is the combination of proteolytic enzymes with bioflavonoids and herbal ingredients exhibiting anti-inflammatory, antioxidant, and Nrf2 activation effects that makes Prolyt so effective. When taking Prolyt for dealing with any other health issues please take up to eight capsules at a time at least one hour before and two hours after eating. In vitro degradation of amyloid material by four proteases in tissue of a patient with familial amyloidotic polyneuropathy. J Neurol Sci. Beneficial effects of a novel IH636 grape seed proanthocyanidin extract in the treatment of chronic pancreatitis. Digestion. Fibrinolytic and antithrombotic action of bromelain may eliminate thrombosis in heart patients. Med Hypotheses. The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method.Acta Obstet Gynaecol Jpn. Attenuation of contraction-induced skeletal muscle injury by bromelain. Med Sci Sports Exerc. It has been claimed to help with food allergies, celiac disease, autoimmune disease, cancer, and weight loss. Enzymes are catalysts needed to promote the metabolic processes that are critical for life and have many functions, including the building and repair of tissue, digestion, and metabolism. Food enzymes found in raw foods, such as bromalain, an enzyme in pineapple, initiate digestion.


Antigens are foreign substances that stimulate the immune system to defend itself from substances such as bacteria, viruses, and neoplasms, also known as cancer cells. However, it is projected that pancreatic cancer will be the second deadliest cancer by 2030. At present there are not many options available to control this excessive degradation and stop the metastasis of cancer. By opening up new directions in natural approaches to cancer, they bring hope to millions of patients who currently have no real choices for the effective elimination of pancreatic cancer.
Insulin is secreted in response to a rise in blood sugar and whilst the pancreas is equipped to deal with this, overwhelming it with high levels of glucose continually can have negative effects on its function. Foods containing bromelain can help support protein and nutrient digestion, thus supporting pancreatic function.
Frequently, when he performed this analysis one could observe that the red blood cells were clumped together and not functioning well. The combination of trypsin and chymotrypsin (often along with bromelain) have been used in protocols for breaking down tumors in the body.
He further proposed that pancreatic enzymes would most likely be useful as a cancer treatment. In terms of the theoretical foundation, the exact mechanism of action has never been demonstrated.
However, recent evidence demonstrates that orally ingested pancreatic proteolytic enzymes are acid stable, pass intact into the small intestine and are absorbed through the intestinal mucosa into the blood stream as part of an enteropancreatic recycling process. Studies of people having dental, nasal, and foot surgeries found it did reduce inflammation. Curcumin is a potent scavenger of free radicals such as superoxide anion radicals, hydroxyl radicals, and nitrogen dioxide radicals. OPCs readily cross the blood-brain barrier and thereby may be helpful to persons suffering from allergic reactions or from swelling due to injury.
Pancreatin is an effective enzyme supplement for replacing missing pancreatic enzymes, and aids in the digestion of foods in cases of pancreatic insufficiency. Providing our bodies with a sufficient amount of food enzymes found in raw fruits and vegetables not only aids in digestion, but takes some of the slack off the body, allowing it to redirect its energy toward metabolic processes. When the immune system encounters a foreign substance or antigen, it activates lymphocytes, white blood cells that produce antibodies that seek out and destroy antigens.
According to American Cancer Society 2014 estimates, 46,420 people will be diagnosed with pancreatic cancer in the US and 39,590 deaths are expected to result from it.
However, our research has demonstrated that micronutrients such as vitamin C, lysine, proline, green tea extract and others are effective in blocking collagen digesting enzymes, known as matrix metalloproteinases (MMPs), which facilitate the spread of various types of cancer.
He would then ask the person being tested to take two capsules of Prolyt and come back again in 30 minutes. The specific site along the protein chain where trypsin is active are those with the amino acids lysine and arginine, two of the smaller amino acids. After Beard’s death, the enzyme therapy was largely forgotten and certainly never generated any significant research effort until recently with the funding of my work.
In Europe, bromelain is used to treat sinus and nasal swelling following ear, nose, and throat surgery or trauma. These benefits of quercetin may have important implications for enhancement of athletic and military performance. Therefore, we studied whether a specific combination of these micronutrients can affect the growth and tissue migrating potential of pancreatic cancer cells2.
The test was repeated and invariably the red blood cells acted like billiard balls, bouncing off one another and no longer clumping together. This apparent increase in fitness without exercise training may have implications beyond performance enhancement itself to health promotion and disease prevention. Liers received his PhD in physics in 1969 from the University of Minnesota and has applied his analytical abilities to learning and applying a scientific approach to nutrition. Only 4-5% of the people diagnosed with pancreatic cancer live beyond 5 years after their diagnosis. We observed that this micronutrient combination was able to reduce the growth of pancreatic cancer cells by 62%. This is because pancreatic cancer is usually diagnosed at a very late stage due to a lack of specific symptoms and, similarly to other cancers, no effective cure is available. In addition, these nutrients could completely stop the secretion of MMP enzymes by these cancer cells. As a result, since the micronutrients helped strengthen the surrounding connective tissue, the pancreatic cancer cells were less able to break through this natural barrier and their potential to spread was reduced by up to 87%.



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