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The Diphtheria ELISA is intended for the quantitative detection of IgG antibodies against the Diphtheria toxin to follow-up the success of vaccinations and to determine the immunisation status. Por cuenta de la resistencia bacteriana a estos farmacos, un simple rasguno o la extraccion de una muela podrian volver a ser letales. En los ultimos 30 anos la industria farmaceutica tan solo ha desarrollado dos clases nuevas de antibioticos, mientras las bacterias siguen desarrollando resistencia ante casi todas las terapias conocidas.
En un articulo escrito para la revista New England Journal of Medicine, el infectologo colombiano Cesar Arias, especialista en bacterias que se han hecho resistentes a los antibioticos, recordaba la historia de una mujer de 33 anos que en 1942 estuvo a punto de morir en un hospital de Connecticut (Estados Unidos) cuando una infeccion por estreptococo se esparcio por su cuerpo. Sin muchas esperanzas, los medicos que la atendieron y veian fracasar todos los tratamientos de la epoca decidieron jugar la ultima carta y conseguir una pequena dosis de una sustancia nueva de la que se comenzaba a hablar en circulos medicos: la penicilina. Aquella mujer no solo se recupero de la infeccion, sino que llego a vivir hasta los 90 anos. Ayer, 70 anos despues de aquel episodio que simboliza una era dorada de la medicina, la directora de la Organizacion Mundial de la Salud, Margaret Chan, reunida en Dinamarca con un grupo de especialistas en enfermedades infecciosas, lanzo una tenebrosa advertencia: “Nos estamos acercando a una era postantibioticos, en la que las operaciones rutinarias serian imposibles y lesiones tan simples como un rasguno podrian ser letales”.
En Europa, las infecciones por bacterias resistentes a algun tipo de antibioticos provocan cada ano la muerte de unas 25.000 personas. Hace unos anos, la Sociedad Estadounidense de Enfermedades Infecciosas resumio en el acronimo Eskape el cartel de las bacterias mas peligrosas por cuenta de su habilidad para eludir nuestras mejores medicinas: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa y Enterobacter. Como lo senalo la doctora Marie-Paule Kieny en el informe La cambiante amenaza de la resistencia antimicrobiana, divulgado por la OMS este mes, este fenomeno de resistencia se debe “al uso apropiado e inapropiado de antibioticos en humanos y animales, ademas de las medidas inadecuadas de control de infecciones”. Las bacterias (ver recuadro) aprovechan varias estrategias para aprender a sobrevivir a nuestra mejor arma contra ellas. Sin antibioticos eficaces, la medicina tendria que prescindir ademas de la quimioterapia contra el cancer y los trasplantes de organos, pues los pacientes sometidos a estos tratamientos por lo general sufren un deterioro de sus sistema inmunitario y contraen infecciones.
En Tailandia, por ejemplo, un programa de uso inteligente de antibioticos permitio reducir entre 18% y 46% el uso innecesario de medicamentos.
El jefe del equipo negociador del gobierno aseguro que la firma del acuerdo para desvincular a menores de las filas de las Farc es un avance crucial en el proceso para terminar la guerra. Every year, around 20,000,000 people choose to spend their vacation on the board of a cruise ship (21,556,000 passengers reported in 2014, expected to increase to 24,146,000 by 2018). But despite the incredible amenities and hard-to-refuse perks, the “once-in-a-lifetime” experience as a cruise tourist has started to be seen more as “dangerous” and “life-threatening” than “unique” and “unforgettable.” The public perception of the cruise industry has plummeted, and a significant percentage of the usual customers of cruise lines are looking elsewhere for spending their family vacations. An average of 14 ships per year report outbreaks of diarrheal illness, and the cause is invariably the same: norovirus. Although norovirus outbreaks make headlines and usually constitute the main reason cruise lines’ credibility plummets, there isn’t always a clear indication that the contamination happened on board.
Despite the numerous laws and strict regulations concerning safety at sea, the number of cruise ship accidents increased directly proportional to the number of cruise ships built annually. Inspections are carried out periodically to assess structural fire safety, proper functioning of firefighting systems, and lifesaving equipment. Five firefighting teams undergoing extensive and advanced shipboard training, 4,000 smoke detectors, 500 extinguishers, 5,000 sprinkler heads, and about 6 miles of fire hose – the basic kit of an average cruise ship – should be reassuring enough for any tourist, no matter how panicked. Norwegian Dawn, 2005: A 70-foot wave hit the Norwegian Dawn while sailing between New York City and the Bahamas, flooding at least 62 cabins and injuring two passengers. Costa Concordia, 2012: The ship toppled on its side after hitting a reef on the coast of Tuscany, Italy, killing 32 and injuring 64 of the total 4,200 passengers on board. Carnival Triumph, 2013: Due to a fire in the engine room, the ship was stranded at sea in the Gulf of Mexico for almost a week, without power, air conditioning, or a functioning septic system, leaving passengers to survive on limited reserves of food and water. Seabourn Spirits, 2005: While sailing about 100 miles off the coast of Somalia, the ship was attacked by pirates in speedboats who, armed with machine guns and grenades, opened fire on it. Carnival Splendor, 2007: Similar to the Carnival Triumph, the Splendor was stranded at sea after the engine room caught fire, cutting off power and leaving the 3,299 passengers without toilets and limited food resources for 13 hours.
The polished decks of a cruise ship can lead to many slip and fall accidents, rapidly bringing what could have been a memorable vacation to a tragic end. Unfortunately, when it comes to proving it was the staff’s or the company’s negligence that caused the accident, passengers have little chance of succeeding on their own. Other precautions cruise lines typically include in the contract (that largely goes unread) are a damages cap (little over $500,000), a limit period to file suit (a year, in most cases), and sometimes a requirement to give notice of the intention of filing a lawsuit six months prior to filing. Ultimately, anyone who boards a cruise ship should be aware of the risks and safety challenges the cruise ship industry is still confronted with.
Andrew Winston is a partner at the personal injury law firm of The Law Office of Andrew Winston.
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Now, in a study published in The Journal of Biological Chemistry, the researchers present the first characterisation of what makes up this coat. Using NMR spectroscopy, the researchers discovered that the coat is made up of two types of exopolysaccharides (EPS), which are long sugar-containing molecules that many bacteria use to encapsulate themselves.
This strain of Lactobacillus johnsonii is now being taken through farm-scale trials to assess its potential use to combat pathogenic infections of poultry by bacteria such as C.
Researchers from Australia found something completely new while conducting a genetic study of the pathogenesis of an enteric disease in birds. A strain of probiotic bacteria that can fight harmful bacterial infections in poultry has the ability to change its coat, according to new findings from the Institute of Food Research.
Some gut bacterial strains are specifically adapted to use sugars in our gut lining to aid colonisation, potentially giving them a major influence over our gut health. Scientists have discovered that bacteria found in a traditional Japanese pickle can prevent flu.
By way of a light-driven bacterium, Utah State University biochemists are a step closer to cleanly converting harmful carbon dioxide emissions from fossil fuel combustion into usable fuels. A powerful new material developed by Northwestern University chemist William Dichtel and his research team could one day speed up the charging process of electric cars and help increase their driving range. A portable power-free test for the rapid detection of bacterial resistance to antibiotics has been developed by academics at Loughborough University and the University of Reading.
Despues de inyectar unas cuantas dosis directamente en su torrente sanguineo, en cuestion de horas comenzaron a notar sintomas de mejoria. En los registros de la historia de la medicina quedo inscrita como una de las primeras personas que se salvaron de la muerte gracias al descubrimiento de los antibioticos. En Estados Unidos, de los dos millones de personas que adquieren infecciones por bacterias resistentes a los antibioticos dentro de los hospitales —el escondite favorito de las superbacterias—, unas 90 mil fallecen.
En el caso de la tuberculosis, en 2010 se reportaron 290.000 nuevos casos de tuberculosis resistente a multiples medicamentos y por primera vez en 77 paises se detectaron casos de tuberculosis extremadamente resistente a medicamentos.
En el caso de los humanos, algunos estudios apuntan a que mas del 50% de la prescripcion de antibioticos no es necesaria y en el caso del sector agro-ganadero, los antibioticos se convirtieron en una forma eficaz de aumentar la productividad.
Tambien las cirugias correrian el riesgo de convertirse en algo tan peligroso como lo fueron en la Edad Media. En el informe divulgado por la Organizacion Mundial de la Salud se recopila una serie de iniciativas globales que de ampliarse y extenderse permitirian minimizar este problema.
En Noruega, la introduccion de vacunas en los cultivos de salmon redujo en 98% el uso de antimicrobianos. With amenities such as piazza-style atriums, planetariums, water parks, rock climbing walls, full-sized carousels, skydiving, and bumper cars, cruise ships are more like floating cities offering infinite opportunities for world-class food and leisure. What has happened is, a myth has been shattered regarding cruise ships’ safety and unsinkability, becoming clearer that the luxurious floating cities are not, in fact, as safe as advertised. Passengers are usually the ones deemed responsible for carrying the virus on board and then leading to its rapid spread through contact with doorknobs, handrails, toilet seats, etc. In a study published in Clinical Infectious Diseases magazine, researchers from the Boston University pointed out to the staff’s failure to clean restrooms and conducting proper examination of the cleaning processes as the principal cause of the outbreak. No doubt about it, technological advances have allowed the industry to make significant improvements in the areas with increased risk. And yet, a closer look at the cruise ship industry today reveals that it is still facing tremendous safety and security challenges.


Of the 300 passengers, none was hurt, and the ship managed to escape and safely sail to Seychelles.
Although cruise ships may not seem a likely location to cause such accidents, it is often the water on deck, spilled drinks, recently mopped floors, uneven flooring, improper lighting, and obstructed pathways that may cause a passenger to fall and hurt himself. And that’s because big cruise lines take the necessary precautions to discourage people from suing. Theoretically, passengers are entitled to sue not only over injuries sustained in trip and fall accidents caused by the cruise line’s staff, but also over norovirus and motion sickness, although with limited chances of success. As ships are getting bigger in order to accommodate a larger number of people, the issues of effective evacuation and quantity of lifesaving equipment naturally come into mind. I read a report that Juice Plus contains many of the important nutritional constituents of the fresh fruits and vegetables from which it is made. It s really simple to start with a goal of covering the cost of your own family s Juice Plus+ and then build from there, if you wish.
Jay founded National Safety Associates (NSA) with $500 and has served as President and CEO since inception. Recently, researchers at the Institute of Food Research, which is strategically supported by the Biotechnology and Biological Sciences Research Council, found that the bacteria make coats for themselves that play important roles in colonisation in this strain. This will give us a better idea of the role of the coat and help in the development of these bacteria as a way of combatting C.
This capsule may help the bacteria to cope with environmental stress, or aid colonisation and adhesion. Structural features, such as the phosphorylation patterns, are likely to be a major influence on how well bacteria adhere.
Y por si esto fuera poco, en los ultimos 30 anos la industria farmaceutica tan solo ha desarrollado dos clases nuevas de antibioticos.
Todo esto a costa de que las proximas generaciones vuelvan a enfrentarse a una epoca en que, como lo recordo Chan, una simple herida en la piel podia cobrar una vida. Gracias a las medidas de asepsia y los antibioticos, los cirujanos lograron desarrollar su ciencia. Moreover, following a series of calamities in the past few years, they came across as crime and disease hotbeds. The norovirus thrives in closed spaces such as dormitories, health care facilities, nursing homes, and cruise ship cabins; it spreads fastest through contaminated food and water and causes vomiting, loose stool, headache, fever, and muscle pain. Of the 8,344 objects marked with a substance visible only exposed to ultraviolet light, including flush handles, toilet seats, door handles, and other objects in toilets, only 37 percent were cleaned daily. The International Maritime Organization (IMO) mandates global standards regarding cruise ship safety and operation, while the Cruise Lines International Association (CLIA) and its partnership with the U.S. These kind of incidents don’t always have severe consequences, but it’s not uncommon for slip and fall incidents to lead to broken bones, back injuries, brain injuries, or even death by drowning. The contract handed to every passenger who purchases a ticket contains 10 to 15 pages of terms and conditions, also including provisions according to which passengers cannot sue due to emotional distress. The number of norovirus outbreaks, as well mishaps and slip and fall accidents may not be overwhelming compared to their occurrence rate on land, but it certainly is an indication that the cruise ship industry can do more to protect its passengers and ensure not only their comfort, but also their safety and well-being for the entire duration of the cruise. Ita€™s a LIFESTYLE Change beyond weight loss that will transform your body, mind and health without starvation or any fad diets. Different bacterial strains have different EPS structures, and understanding this is important as they represent a key way bacteria interact with the world around them. Other structural modifications such as acetylation are thought to help protect the EPS from the enzymes produced by gut bacteria. This study provides insights into exactly how this works, and future work will focus on unpicking how the EPS molecules in the coat contribute to colonisation and pathogen exclusion. The largest ship ever constructed, the Allure of the Seas, measures 1,181 ft., has around 100,000 metric tons, a theater with 1,380 seats, a two-deck dance hall, an ice skating rink, and even its own Starbucks, the first ever to be built on the board of a cruise ship. The baby-changing tables marked on the three ships that provided them were never cleaned during the three-year period the study lasted. Coast Guard ensures all ships meet the international requirements for safety, security, and environmental protection.
Whether they slipped and fell or were stranded in the middle of the ocean with limited supplies of food and water, they must document the existence of real physical injuries to have a case. In addition, microorganisms are essential for the production of foods such as cheese, yoghurt, other fermented foods, bread, beer and wine.
Further analysis of the genes by IFR PhD student Enes Dertli uncovered their potential roles in the capsule biosynthesis process but more research is needed to fully understand the system, and also how it is regulated.



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