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When I started helping Brewer’s Friend as a technical adviser I couldn’t help but notice that the mash pH predicted by its brewing water calculator was way off. Since Brewer’s Friend is an online recipe calculator the new calculator would also become an online tool. That was 3 months ago and after many long nights of coding, re-coding, testing and even running more mash pH experiments version 1.0 has finally been released and is available on Brewer’s Friend.
Wide range of supported acids including the less commonly used citric, tartaric and acetic acid. For now this tool is only available as a stand-alone calculator but Brewer’s Friend is planning to integrate it into the recipe editor.
In subsequent posts I’m planning to write more about some of the discoveries I made while writing this tool and how it’s mash pH prediction does compared to actual mash pH data that I have. How come there’s always such a difference in the mash pH when switching back and forth between SRM and malt bill. When you change SRM, are you also correctly specifying the percentage of color that comes from roasted malts? When I use it to assess the impact of boiling the water my Alkalinity goes down from 147 as CaCO3 to 38.8.
Please can you shed a little light on how the calculator assesses the the change in Alkalinity due to boiling. To find the alkalinity precipitation for boiling the calculator assumes that the resulting CO2 content of the water will match the atmospheric CO2 partial pressure. Andrew, For a number of pH measurements (experiments and actual brewed batches) I have compared Martin’s spreadsheet and my new water calculator. One of the reasons why the models diverge is that the Brewer’s Friend calculator implements the underlying water chemistry more accurately. Would you be interested in having a spreadsheet import function for the Brewer’s Friend water calculator to make it easier to get a 2nd opinion on mash pH? I did some additional checking, and I noticed that the your calculator presents a different result based on malt bill vs beer color (SRM) options. I used Martin’s sheet so far and I exported water profile so I can repeat it if I am satisfied with result.
The current version has the ability to save the settings and gives a link to retrieve that record.
The bug was a typo in the code and it only shows up when there are already ions in the water.
So my question to you is given the choice of CRS, lactic acid or phosphoric acid to reduce the alkalinity of the water by about 150 ppm for British style ales that predominantly use Maris Otter which would you choose? When playing with the salt additions I seemed to notice that the Range Check indicators under each ion in the Overall Water Report section are in the wrong order. I would enter the pre boil volume, but I don’t think it differs enough from the post boil volume to mater.
Chalk can only be handled by the calculator when there is a mash, which requires grain to be specified. I should add a note for this to the overall water report when a user added chalk but no grist. I haven’t worked on the spreadsheet in a while and it was not designed to deal with that.
I’m about to use that wonderful calculator for the first time and I have a question concerning sparge water. Because in batch sparge, where you mix again the grains with the sparge water in the lauter tun, in theory, some of the water retained by the grains from the first run-off (which is supposed to be at ph 5.4) is mixed with a certain fixed amount of sparge water. Since I do batch sparge and I’m going to acidify sparge water, should I correct in some way the estimated amount of needed acid to target the right ph? The complications from unmanaged diabetes can range from simple things like lack of energy or problems getting a good nights rest to very serious repercussions such as blindness, kidney disease, cardiovascular disease and heart attack. The American Diabetes Association Risk Test for Diabetes can help you determine if you are at increased risk for diabetes or pre-diabetes. Glycated hemoglobin or A1c is that portion or percent of total hemoglobin that has glucose attached to it.
Glycation of hemoglobin has been associated with cardiovascular disease, nephropathy, and retinopathy in diabetes mellitus. In the study glycated hemoglobin (A1c) was compared to fasting glucose for effective screening for diabetes and cardiovascular disease, stroke and coronary heart disease simultaneously. About Speaking of DiabetesSpeaking of Diabetes is produced by Joslin Diabetes Center for people with diabetes and those who care for them..
Joslin Diabetes Center, a teaching and research affiliate of Harvard Medical School, is a one-of-a-kind institution on the front lines of the world epidemic of diabetes - leading the battle to conquer diabetes in all forms through cutting-edge research and innovative approaches to clinical care and education.
This entry was posted in Diabetes Day2Day, Technology and tagged finger pricks, glucose checks, near infrared technology.
If only it didn’t hurt and patients didn’t need to bleed, physicians and diabetes educators would be inundated with blood glucose records, instead of the current situation where many patients have to be cajoled into checking. Antoine Kaldany, M.D, Associate Clinical Professor of Medicine at Harvard Medical School and Senior Physician at Joslin Diabetes Center serves as a scientific advisory board member for the company developing a real-world model.
The advent of micro-gauge needles and alternate-site testing has made checking easier and less painful, but neither of these advances have quite hit the mark.
The key to painless accurate blood glucose reading is to find a way to measure a specific unique property of glucose that can be measured non-invasively without interference from non-glucose components.
The meter device, which looks similar to a small pager, can measure glucose from your finger or earlobe.
Since its initiation, blood glucose monitoring has been hailed as the cornerstone of diabetes control. Hi, my mom has had disbeties for about 30 years and know suffers from prickly heat all over her body and is disabled , is there anything she can do or take to relieve her heat symptom please . MoisturizersMoisturizers help prevent dryness, bruising, and tearing, but used alone they have no effect on wrinkles. Herbs and SupplementsMany herbal products and supplements are advertised as being healthy for the skin.
We procure directly from the growers and refiners to ensure high quality produce and product. Since I have done extensive work on brewing water and mash chemistry already I took this as an opportunity to develop a new Mash Chemistry and Brewing Water Calculator from scratch. This worked very well in its favor since it is very cumbersome to model complex systems in spreadsheets. In most cases that might be reverse osmosis water when the tap water is suitable for mashing.
I have stopped using my spreadsheet a while ago since it was always a hassle to open yet another tool.
That can make a huge difference in the estimated mash pH since roasted malts have less acidity per Lovibond than crystal malts.
This may become a nonissue once the calculator is integrated with the recipe design portion of the software.
To satisfy this it allows CO2 to escape and precipitates all CaCO3 that exceeds the solubility product for Ca and CO3. Should I use it or just pass, only with some eventual small addiction into mash for pH correction?
My pH results were almost in a ballpark, as predicted in the calc Awesome job Kai, thank you ! There are a number of water and grist configuration where BW does poorly with respect to mash pH prediction. That helps brewers who know that parameter since base malt pH is the largest factor in mash prediction uncertainty. I have been thinking about that feature and it should not be all that difficult to implement. The bicarbonate + carbonate gives you slightly more alkalinity than the standard approach of using only bicarbonate to calculate alkalinity. There will also be more bookkeeping options for Brewer’s Friend users that will make it easier to keep track of water profiles and treatment. I am pleased with code option, we can save just code and retrieve profile simply by pasting code.. I was trying out CRS because I am in an area with moderately hard water and got fed up with boiling when making lighter coloured ales. I’m taking the lazy way out this weekend and making an extract brew instead of all grain, but had a question on the calculator.
A high score may indicate that you have pre-diabetes or at risk for pre-diabetes. Take the test and find out for sure.
Red blood cells that contain the hemoglobin circulate in the bloodstream for 3 or 4 months before being broken down and replaced.
A new process using near infra-red may be on the way to a technological revolution in blood glucose meter design. There is no needle system that is entirely discomfort free and no matter how contained, many bystanders are not comfortable with the sight of other peoples’ blood.
If the device proves as promising as thought, it is likely that it will still take years for a fully realized consumer model to hit the market. The thinning skin is prone to injuries and damage.The deeper layer of the skin, which provides the framework for the surface skin layers, loosens and unravels. Liver spots do not require treatment, although some people are bothered by their appearance.
Alpha hydroxy acids (AHAs) ease the shedding of dead skin cells and may even stimulate growth of collagen and elastin. The Food and Drug Administration (FDA) does not regulate herbal remedies and dietary supplements.
The goal was to build something that provides a simple and intuitive user interface yet implements the underlying chemistry to at a level of accuracy that is generally not done in brewing water calculators.
PHP, or any other programming language for that matter, makes that type of modeling much easier.


I currently have an additional feature for the calculator on the back burner which would allow the user to enter actual GH&KH measurements of the post treatment water to account for a less then ideal alkalinity precipitation. Spreadsheets have a problem with that since math that is involved is difficult to implement and debug in a spreadsheet.
With the same alkalinity sodium hydroxide raises mash pH more than baking soda since baking soda is the salt of a weak acid (carbonic acid). The strong acids (HCl, H2SO4 and CRS) are not all that popular in the US which is why I think you were the first to run into this. However, I don’t really like that fact that the anion content is increased so much, especially the chloride level. When they come in contact with blood there is an ion exchange which generates an electrical impulse. The information derived from accurate real-time glucose values is essential to making immediate insulin adjustments as well as overall long-term medical management decisions. All materials contained on this site are protected by United States copyright law and may be used for personal, noncommercial use only. Older skin sags and forms furrows.Oil-secreting glands shrink, leaving the skin without a protective layer of oil. For aging skin, dermabrasion is effective for wrinkles on the upper lip and chin, but it cannot be used around the eyes. In fact the only calculator that goes to that extent is A.J deLange’s NUBWS (Nearly Universal Brewing Water Spreadsheet). In addition to that modern web browser technology makes it simple to create dynamic forms that can readily adjust the form to only asking the user for information that is actually needed based on the context. We also plan to support actual malt pH properties for custom malt entries in case brewers have them.
BF will soon add the ability to see all your stored water calculations when you sign up for a trial or full membership. If we add this, it would be part of the Brewer’s Friend recipe editor print function. Reading around the forums people seem put off using lactic acid because of the risk of sour flavours and also worry about interfering with the malt phosphates if they add phosphoric acid. Thus, A1C readings higher than about 6% indicate higher than normal amounts of glucose roaming the bloodstream in the past 120 days.
Finding a way to take accurate readings without having to prick the skin and draw blood is like catching the brass ring on the carousel. People with oily skin should use humectant moisturizers.Other compounds, such as monolaurin, contain mixtures of fatty molecules (lipids). Skin care products are also made from polyhydroxy acids (PHAs) and beta hydroxy acids (BHAs). Any substance that affects the body's chemistry can produce side effects that may be harmful.
Some doctors use dermabrasion instead of lasers for darker skin.Your doctor will determine if your skin type and problem area are suitable for dermabrasion.
Similar to a mirror, the energy is reflected back at a specific wavelength unique to glucose that is read by the meter. The device takes two measurements; the first measures the interstitial fluid and cell mater.
All the non-invasive methods for checking blood glucose developed so far have fallen too far short in accuracy. You may not alter or remove any trademark, copyright or other notice from copies of the content. PhotoagingExposure to sunlight is the most important cause of prematurely aging skin (a process called photoaging) and skin cancers.Exposure to ultraviolet radiation from sunlight accounts for most of the symptoms of premature skin aging.
Laser treatment may be more effective than cryotherapy and may have fewer side effects.Bleaching creams are widely available, but they are not as effective as a chemical peel.
These help restore the skin's natural barrier against moisture loss and damage.Most moisturizers contain combinations of these compounds. Strong exfoliation methods may not be suitable for people with dark skin because scarring or discoloration may result.
Research suggests that PHA products may cause less skin irritation than AHA or BHA products.Acid concentrations in over-the-counter AHA preparations are 2 - 10%. Check with your doctor before using herbal products and supplements.Some natural remedies can cause the skin to be extra sensitive to light (photosensitivity).
Be aware that dermabrasion may not completely improve skin problems such as wrinkles and sun damage.Standard Dermabrasion.
This is surgery that improves wrinkles on the forehead, including the horizontal wrinkles and vertical wrinkles between the eyebrows.
High concentrations of the bleaching ingredient can cause permanent loss of skin color.PurpuraPurpura occurs when tiny blood vessles called capillaries break and leak blood into the skin. They usually have other ingredients, such as alpha hydroxy acid, sunscreen, collagen, and keratin.
Standard dermabrasion uses a rotating brush that removes the top layers of a person's skin. It can also improve crow’s feet wrinkles at the outer corners of the eyes.Surgery can be done using long incisions (open procedure).
It’ seems I should be entering the target post boil volume to get the concentrations correct.
An accurate reading of the blood glucose is obtained by subtracting the results of the first measurement from the second.
In older people, the condition is called senile or actinic purpura and is usually caused by blood vessels that break easily. Collagen and keratin leave a protein film and temporarily stretch the skin, which may reduce wrinkles.Under-Eye CreamsThe skin under the eyes is very thin. These involve using an abrasive material to remove old top layer skin so that new skin can grow. As with chemical peels, dermabrasion removes the upper layers of skin, leaving the underlying layers exposed.
In addition, the ability of the skin to repair itself decreases with age, so wounds heal more slowly.
Types of abrasives include sugar or salt grains, ground fruit pits, aluminum oxide particles, and tiny plastic beads (also called polyethylene beads, or microbeads).
These include citrus oils (grapefruit, lemon, lime, orange, bergamot), cumin, ginger, and angelica root oils.Resurfacing TreatmentsSkin resurfacing (exfoliation) is usually done in the office of a doctor, such as a dermatologist or plastic surgeon. The thinning skin becomes prone to injuries and damage.The deeper layer of the skin, which provides the support structure for the surface skin layers, loosens and unravels. These patches are called petechiae when they are smaller than 3 mm (about a tenth of an inch).
For full-face dermabrasion, a local anesthetic or general anesthesia may be used.Microdermabrasion. Ground fruit pits and aluminum oxide are the strongest scrubs because their particles have rough edges that may injure the skin. AHA may increase the chance of sun damage to the skin, even at concentrations as low as 4%. This is because the different resurfacing methods cannot be done if you have certain medical problems or take certain medicines. Purpura looks like a rash that may appear red at first and gradually turns brown or purple.Treatment. Under-eye products are applied with light dabbing to stimulate absorption of the cream into the skin. For example, a chemical peel cannot done on persons who have severe liver and kidney disease, HIV, or immune system conditions.After any resurfacing procedure, follow instructions about avoiding sun exposure. Apply sunscreen of SPF 30 to protect your new skin from UV damage.Chemical PeelChemical peel is also known as chemosurgery.
Persons with purpura should avoid trauma, including vigorous rubbing of the skin, which may damage the capillaries. Rubbing causes wrinkles to form, which over time can become permanent.CosmeticsCosmetics can be effective in masking the signs of aging skin, including wrinkles and age spots.
A chemical peel removes the top layers of skin so that the new skin that grows back is younger-looking. The two types of sun rays that can injure the skin are ultraviolet A (UVA) and ultraviolet B (UVB).
Some doctors also recommend vitamin C, but its effectiveness is unproven.Seborrheic KeratosesSeborrheic keratoses are common skin disorders in older adults.
When using these products, avoid sunlight and use sun protection.Other Skin TreatmentsCopper Peptides. A chemical peel can also be combined with topical antioxidants such as tretinoin and vitamin C.Your doctor will evaluate your skin type before recommending the type of chemical peel for you.
Anti-wrinkling effects of the mixture of vitamin C, vitamin E, pycnogenol and evening primrose oil, and molecular mechanisms on hairless mouse skin caused by chronic ultraviolet B irradiation. If reddish discoloration is extensive or the skin is sallow, tinted moisturizers may be helpful and can be worn alone or under foundation.Foundation. One advantage of lasers over other resurfacing methods is their ability to tighten the skin. Caking on make-up causes cracks at the wrinkle lines and increases the appearance of aging.
Copper peptides may also help repair skin because it helps the skin grow collagen and elastin. A day or two before the procedure, you may also receive an antibiotic to prevent infection.Chemicals are applied to the skin. A successful procedure can make patients look 10 - 20 years younger, and the results can last for up to 10 years.The procedure helps most around the eyes, nose, and mouth. Cover large areas of the face with a moderate-coverage foundation that has a matte or semi-matte finish. These may include trichloroacetic acid, high concentrations of alpha hydroxy or beta hydroxy acids, or various combinations of the three.In some cases, tretinoin or alpha hydroxy is applied 4 - 6 weeks before, and starting one day after the peel. Laser therapy can also be effective for acne scars that are widespread on the face.When used alone, laser therapy may not completely eliminate crow's feet and other wrinkles, broken blood vessels, or dark circles under the eyes. Sunscreens containing the broad-spectrum UVA absorber, Mexoryl SX, prevent the cutaneous detrimental effects of UV exposure: a review of clinical study results. To reduce swelling, you may be told to keep your head elevated on pillows while lying down.


Because melanomas can hide among seborrheic keratoses, they may go unnoticed without close inspection.
Seborrheic keratoses have an even appearance, whereas melanomas often have a smooth surface that varies in height, color density, and shading.
Blushes and color washes can help conceal the spidery network of dilated capillaries on the nose and cheeks.
The laser technology and source of laser beam used depend on the skin type and severity of the condition. Skin damage from UVB can also occur during winter, especially at high altitudes or in places with snow and ice, which reflect rays onto the skin. These technologies can be combined for different areas of the face and are used to treat a variety of skin conditions:Ablative lasers treat the skin by damaging and removing the skin layers so that new skin can grow. Vitamin D3 ointment is also being tested as a treatment.Risk FactorsExposure to Sun in Childhood. Light-colored shadow, applied along the upper eyelid crease and above the iris (the colored part of the eye) is best for offsetting the appearance of deep-set eyes.
The two types of lasers are: The CO2 laser delivers short pulsed energy or continuous energy into the skin. Medical researchers estimate that most skin damage begins in childhood and adolescence as a result of intermittent, intense sun exposure that causes severe sunburns.Aging.
Slightly deeper shade of the same color can be applied to the lower part of the eyelid and drawn out to the corner.Lips. Most people over age 70 have at least one skin disorder, and many have three or four skin disorders. Lip-setting cream or facial foundation should be applied before lipstick to help prevent it from bleeding into surrounding wrinkles.
But a long life is not the only factor that determines whether a person develops skin problems. Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin. It is also used to treat skin blemishes that result from blood vessel abnormalities, such as port-wine stains.Non-ablative lasers treat the skin by stimulating collagen to grow.
Repetition of this abnormal skin rebuilding causes wrinkles.An important event in this process is the over-production of oxidants, also called free radicals. But these antioxidants can be replaced.Antioxidant ointments, creams, and lotions may help reduce the risk of wrinkles and protect against sun damage. Evidence suggests, however, that given the same risk factors, men and women in the same age groups have the same risks of skin photoaging.
Unlike sunscreens, they build up in the skin and are not washed away, so the protection may last longer.
Some studies report that men are more likely than women to develop non-melanoma skin cancers.SmokingThe skin of smokers in areas of their bodies not exposed to sunlight also seems to age more rapidly compared to nonsmokers in the same age group. Selenium, coenzyme Q10 (CoQ10), and alpha-lipoic acid are antioxidants that can be applied to the skin.
Oxidation may lead to wrinkling by activating the specific metalloproteinases that degrade connective tissue. Heavy smokers in their 40s often have facial wrinkles more like those of nonsmokers in their 60s.Smokers tend to have thinner skin, more and deeper wrinkles than nonsmokers. This is to keep you relaxed and comfortable during the procedure.Energy in the form of light pulses from the laser penetrates the skin quickly.
A two-year, double-blind, randomized placebo-controlled trial of oral green tea polyphenols on the long term clinical and histologic appearance of photoaging skin. Other Factors Responsible for WrinklesIn addition to sunlight, other factors can speed the formation of wrinkles.Cigarette Smoke. Cigarette smokers are also more prone to skin cancers, including squamous cell carcinoma and giant basal cell carcinoma. Research has found that women who smoke have much lower levels of vitamin E secretions in their skin. These cause wrinkles and age-related skin problems to develop sooner. Free radicals also increase the risk of non-melanoma skin cancers.
Studies suggest that smoking and resulting oxidation produce higher levels of metalloproteinases.Air Pollution. A diet with plenty of fresh fruits and vegetables and whole grains along with healthy oils (such as olive oil) may protect the skin from damage by free radicals. Topical  (applied to the skin) vitamin A products have been researched and appoved for treating skin problems due to aging.
Products include natural forms of vitamin A (retinol, retinaldehyde) and chemicals related to vitamin A callled retinoids (tretinoin, tazarotene). These products help repair skin damage due to sunburn and natural aging, such as fine wrinkles, liver spots, and rough skin. Laser resurfacing that only removes thin layers of skin does not have the same severe after-effects as other laser treatments. Side effects include redness, scaling, burning, and itching, which can be treated with corticosteroid cream. During this time, continuous moisturizing and gentle washing is needed to prevent infection. Sunscreen needs to be applied during the day because vitamin A products can cause the skin to be sensitive to sunlight.
Instead, they are common signs of aging. Liver spots are most noticeable on the hands and face. Warning: Women who are pregnant or think they are pregnant should not use any product related to vitamin A. Exposure to sun must be avoided as much as possible during this time and in the future to prevent further skin damage. Their number, sizes, and brownness are determined by skin type, sun exposure, and age. Liver spots are harmless, but they should be distinguished from lentigo maligna, which is an early sign of melanoma. Risk of complications from ablative laser resurfacing depends in part on the surgeon's experience.
Vitamin C. Vitamin C, or ascorbic acid, is a strong antioxidant that may also help rebuild collagen. The increased pigmentation may be brought on by exposure to sun or other forms of ultraviolet light, or other unknown causes. Though there are many vitamin C products, none has been approved as a treatment for age-related skin conditions. People with a history of herpes simplex may experience flare-ups of fever, facial pain, and flu-like symptoms for 5 - 6 days after the procedure. Persons with darker skin may need to avoid the procedure, because it can cause changes in skin color or uneven skin color.Other Exfoliation ProceduresThermal Resurfacing. In laboratory studies, vitamin C seems to reduce or even protect against damage to skin cells caused by UV radiation. Vitamin C also seems to help skin cells survive after exposure to UV rays.
Leaking increases when you are lying down.Protecting Against Sunlight and UV RaysAn important way to prevent skin damage is to avoid too much exposure to sun and ultraviolet light. Like vitamin C products, none of these antioxidants has been approved as a treatment for age-related skin conditions. Read packaging label to learn when and how to apply sunscreen.Wear clothing to protect against the sun.
In addition, the antioxidants are not well absorbed by the skin and have only a short-term effect.
This causes the collagen to contract, improving the appearance of wrinkles.Intense Pulsed Light. Intense pulsed light (IPL) uses filters to deliver different wavelengths of light to the skin. IPL is used to treat a number of photoaging skin problems, and it appears to have long-term effects. Unlike laser light, which uses one color wavelength (such as green or red), intense pulsed light starts with a full spectrum of light. The doctor can then block off specific wavelengths depending on how shallow or deep the treatment.Injectable Skin FillersInjectable skin fillers are a common means of reducing wrinkles and folds. The procedure usually involves using a tiny needle and syringe to inject the filler material under the skin of the area to be treated. For example, fillers are used to enhance the lips to make them fuller.Skin fillers are made of different materials. Some materials come from natural or human sources, such as fat taken from another part of your own body. Your doctor can tell you the risks and complications of the specific filler that is recommended for you. Forehead furrows, frown lines, and crow’s feet are the kinds of wrinkles that botulinum treats successfully.Botulinum toxin is a substance made by a bacterium. This blocks the muscles from contracting thus reducing wrinkles or even causing them to disappear. It only relaxes the muscles that link to the wrinkles that are being treated.Botulinum is recommended for persons 30 - 50 years old, whose wrinkles are just starting to form.
Botulinum does not work for deep wrinkles, which are common in older persons.Improvement is noticed about 1 week after the injections.
Repeated use is safe and effective.Before treatment, tell your doctor if you are allergic to eggs because botulinum is prepared with an egg base. Simple facelift surgeries are done in a doctor's office under local anesthesia. More involved surgeries are done in a hospital under general anesthesia. The facelift procedure may be one of the following:Superficial musculoaponeurotic system (SMAS) is the most common facelift procedure. The surgeon makes incisions at the hairline and gently separates the skin from the underlying tissue and muscles. The muscles are tightened and excess fat and tissue, such as fat under the chin and neck, are removed.
Variations of the SMAS procedure are done depending on the area of the face and depth of tissue to be treated.Endoscopic facelift is a less invasive surgery.
With endoscopic facelift, scarring is minimal and recovery is usually faster than with the SMAS procedure.



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