That may explain why a traditional Mediterranean diet rich in olive oil is linked to lower risk of cardiovascular disease, researchers say. Violi and his colleagues tested the effect of adding extra virgin olive oil (EVOO) to a Mediterranean diet based on fruits, vegetables, grains and fish, with only limited consumption of dairy or red meat. On two separate occasions, researchers gave 25 healthy people a typical Mediterranean lunch. Blood tests done before and two hours after the meals found that blood sugar rose after eating in all the participants, which is normal.
That’s in line with previous research linking EVOO to elevated levels of insulin, a hormone that helps convert glucose into energy, Violi said. It’s unclear, though, why the blood tests after meals with olive oil also showed lower levels of low-density lipoprotein (LDL), the bad kind of cholesterol that builds up in blood vessels and can lead to atherosclerosis, blood clots and heart attacks. Violi’s team also found that after meals with corn oil, people had significantly higher levels of two kinds of LDL than they did after meals supplemented with extra virgin olive oil. The study is quite small, and didn’t explore whether adding corn oil to meals might be better than including no oil at all, the researchers acknowledge in the journal Nutrition and Diabetes. Even so, they argue, theirs is among the first studies to link a Mediterranean diet containing extra virgin olive oil to lower blood sugar and LDL cholesterol after meals. The buildup of thick and dead skin formed by the friction or pressure in elbows or knees or in ankles causes the skin to turn black. The sugar present in this home remedy work as exfoliate and the olive oil will moisturize the skin. Lemon juice has natural bleaching property and honey moisturizes the skin preventing darkening of the skin.
Apply the mixture and rub in circular motion, allow it to dry and wash it off to get light colored skin. This oil has natural bleaching properties and it also softens the rough skin on the knees and elbow giving it smoothness and glow.
Aloe Vera reduces the sun damage caused to the skin due to overexposure of the elbows and knees to the sun. Apply the fresh gel to the knees and elbows and leave it for half an hour to get fresh looking skin on your elbows and knees.
Using sunscreen lotions while going out reduces the chances of developing dark skin on the exposed parts. You can also use it as moisturizer after shower on elbows and knees to lighten the skin color.
When used together this home remedy to reduce the dark color of the skin as they cleanse and moisturize the skin. Fruits like lemon, tomato and grapes have bleaching property and help to get rid of black skin when used regularly.
Apply any natural oil like olive oil, sesame seed oil or coconut oil on the skin to reduce the dryness and darkening of skin. I need to get rid of my dark knees tommorow I have an assembly and I have to wear a skirt and the whole school will be watching me !!!!!!!!!!! My knees are really very dark and tomorrow I have football match in school and I have to wear shorts what to do pls help!!! This site is for information and support only and NOT a substitute for professional medical advice, diagnosis, or treatment. The accuracy of diagnostic results has improved significantly with advances in ultrasonography, CT, MRI, and scintigraphy. Preliminary results of a large trial have shown that single-incision laparoscopic cholecystectomy (SILC) is safe, and, although it requires more operating time, cosmetic satisfaction was higher among patients who had SILC compared to those who underwent traditional (4-port) laparoscopic surgery. A new investigational procedure called Natural Orifice Translumenal Endoscopic Surgery (NOTES) is enabling surgeons to remove the gallbladder through the mouth, stomach, rectum or vagina.
The American Society for Gastrointestinal Endoscopy has published several guidelines for the endoscopic treatment of gallbladder and bile duct stones. Gallstones are small, hard deposits that form in the gallbladder, a sac-like organ that lies under the liver in the upper right side of the abdomen. The formation of gallstones is a complex process that starts with bile, a fluid composed mostly of water, bile salts, lecithin (a fat known as a phospholipid), and cholesterol. The gallbladder serves as a reservoir until bile is needed in the small intestine to digest fats. This part of the digestive process enables the emulsified fat, along with important fat-absorbable nutrients (such as vitamins A, D, E, and K), to pass through the intestinal lining and enter the bloodstream. Cholesterol is not very soluble, so in order to remain suspended in fluid it must be transported within clusters of bile salts called micelles. If the imbalance worsens, cholesterol crystals form (a condition called supersaturation), which can eventually form gallstones. Supersaturation and cholelithiasis can occur as a result of various abnormalities, although the cause is not entirely clear. The cells lining the gallbladder may not be able to efficiently absorb cholesterol and fat from bile.
Gallbladder disease can occur without stones, a condition called acalculous gallbladder disease.
Acute acalculous gallbladder disease usually occurs in patients who are very ill from other disorders.
Chronic acalculous gallbladder disease (also called biliary dyskinesia) appears to be caused by muscle defects or other problems in the gallbladder, which interfere with the natural contractions needed to empty the sac. The mildest and most common symptom of gallbladder disease is intermittent pain called biliary colic, which occurs either in the mid- or the right portion of the upper abdomen. The primary symptom is typically a steady gripping or gnawing pain in the upper right abdomen near the rib cage, which can be severe and can radiate to the upper back. Changing position, taking over-the-counter pain relievers, and passing gas do not relieve the symptoms.
The episodes typically occur at the same time of day, but less frequently than once a week.
Digestive complaints, such as belching, feeling unusually full after meals, bloating, heartburn (burning feeling behind the breast bone), or regurgitation (acid back-up in the food pipe), are not likely to be caused by gallbladder disease.
Between 1 - 3% of people with symptomatic gallstones develop inflammation in the gallbladder (acute cholecystitis), which occurs when stones or sludge block the duct.
Pain may also radiate to the back or occur under the shoulder blades, behind the breast bone, or on the left side.
About a third of patients have fever and chills, which do not occur with uncomplicated biliary colic. Chronic gallbladder disease (chronic cholecystitis) involves gallstones and mild inflammation. Complaints of gas, nausea, and abdominal discomfort after meals; these are the most common symptoms, but they may be vague and difficult to distinguish from similar complaints in people who do not have gallbladder disease.
As in acute cholecystitis, patients who have these symptoms should seek medical help immediately.
In most cases of obstruction, the stones block the cystic duct, which leads from the gallbladder to the common bile duct.
About 10% of patients with symptomatic gallstones also have stones that pass into and obstruct the common bile duct (choledocholithiasis). The most serious complication of acute cholecystitis is infection, which develops in about 20% of cases.
Research shows that survival rates for gallbladder cancer are on the rise, although the death rate remains high because many people are diagnosed when the cancer is already at a late stage. Because gallstones are related to diet, particularly fat intake, the incidence of gallstones varies widely among nations and regions.
Defects in transport proteins involved in biliary lipid secretion appear to predispose certain people to gallstone disease, but this alone many not be sufficient to create gallstones. People with diabetes are at higher risk for gallstones and have a higher-than-average risk for acalculous gallbladder disease (without stones). Metabolic syndrome is a cluster of conditions that includes obesity (especially belly fat), low HDL (good) cholesterol, high triglycerides, high blood pressure, and high blood sugar. Although gallstones are formed from the supersaturation of cholesterol in the bile, high total cholesterol levels themselves are not necessarily associated with gallstones. Unfortunately, some fibrates (drugs used to correct these conditions) actually increase the risk for gallstones by increasing the amount of cholesterol secreted into the bile. Maintaining a normal weight and avoiding rapid weight loss are the keys to reducing the risk of gallstones. Although it would be reasonable to believe that drugs used to lower cholesterol would protect against gallstones, most evidence has found no gallstone protection from these drugs.
The challenge in diagnosing gallstones is to verify that abdominal pain is caused by stones and not by some other condition. In patients with abdominal pain, causes other than gallstones are usually responsible if the pain lasts less than 15 minutes, frequently comes and goes, or is not severe enough to limit activities. Blood tests showing high levels of pancreatic enzymes (amylase and lipase) usually indicate a diagnosis of pancreatitis.
In patients with known gallstones, the doctor can often diagnose acute cholecystitis (gallbladder inflammation) based on classic symptoms (constant and severe pain in the upper right part of the abdomen).
Blood tests are usually normal in people with simple biliary colic or chronic cholecystitis. Bilirubin and the enzyme alkaline phosphatase are usually elevated in acute cholecystitis, and especially in choledocholithiasis (common bile duct stones). Levels of liver enzymes known as aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are elevated when common bile duct stones are present. Ultrasound does not appear to be very useful for identifying cholecystitis in patients who have symptoms but do not have gallstones. Ultrasound is also not as accurate for identifying common bile duct stones or imaging the cystic duct.
Magnetic Resonance Cholangiography (MRCI), or Magnetic Resonance Cholangiopancreatography (MRCP).
Advances in technology have made ultrasonography, CT, and MRI the primary imaging tests for suspected gallbladder disease.
In oral cholecystography, the patient takes a tablet containing a dye the night before the test.
In cholangiography, a dye is injected into the bile duct and x-rays are used to view the duct.
The patient lies on a table under a scanning camera, which detects gamma (radioactive) rays emitted by the dye as it passes from the liver into the gallbladder. The test can take up to 2 hours, because each image takes about a minute, and images are taken every 5 - 15 minutes. If the dye does not enter the gallbladder, the cystic duct is obstructed, indicating acute cholecystitis. Occasionally, the scan gives false positive results (detecting acute cholecystitis in people who do not have the condition).
However, this technique is invasive and carries a risk for complications, including pancreatitis.
Acute pain from gallstones and gallbladder disease is usually treated in the hospital, where diagnostic procedures are performed to rule out other conditions and complications. Guidelines from the American College of Physicians state that when a person has no symptoms, the risks of both surgical and nonsurgical treatments for gallstones outweigh the benefits. Very small gallstones (smaller than 5 mm) may increase the risk for acute pancreatitis, a serious condition.
There are some minor risks with expectant management for people who do not have symptoms or who are at low risk.
The slight risk of developing gallbladder cancer might encourage young adults who do not have symptoms to have their gallbladder removed.
Gallstones are the most common cause for emergency room and hospital admissions of patients with severe abdominal pain.
Common bile duct stones pose a high risk for complications and nearly always warrant treatment. In the past, when common bile duct stones were suspected, the approach was open surgery (open cholecystectomy) and surgical exploration of the common bile duct.
Endoscopic retrograde cholangiopancreatography (ERCP) with endoscopic sphincterotomy (ES) is now the most frequently used procedure for detecting and managing common bile duct stones. Laparoscopic cholecystectomy has taken a secondary role in the detection and removal of common bile duct stones. Oral drugs used to dissolve gallstones and lithotripsy (alone or in combination with other drugs) gained popularity in the 1990s.
Discuss eating sugar-free and fat-free with your doctor for advice and recommendations specific to your pregnancy since each one is different and dietary needs can vary depending on other health conditions. After 13 weeks it was found that those who had the big breakfast experienced greater reductions in blood pressure and HbA1c (a measure of long term blood sugar) than the small breakfast group. It seems that the big breakfast is probably promoting release of hormones like ghrelin that lead to feeling satiated. This is not a license for diabetics to tuck into pancakes and syrup for breakfast, but it is an indication yet again that a substantial breakfast of well-chosen healthy foods has long term metabolic effects throughout the day. France police officers recently fined a woman for wearing a burkini while she was laying on the Riviera coast. For one meal they added 10 grams (about 2 teaspoons) of extra virgin olive oil, and for the other they added 10 grams of corn oil. These conditions killed an estimated 17.5 million people in 2012, most often from heart disease or stroke, according to the World Health Organization (WHO). Leaning onto the table using the elbows or kneeling down while you offer prayers can make the skin look dark. It also moisturizes the skin and prevents the dryness which may lead to darkening of the skin. Ultrasonography has emerged as the primary diagnostic test in suspected gallbladder disease due to its availability, high accuracy, and safety.
The first two transoral and transvaginal cholecystectomies in the NOTES clinical trials were recently performed in the U.S. It is first produced by the liver and then secreted through tiny channels that eventually lead into a larger tube called the common bile duct, which leads to the small intestine.
Most flows into the gallbladder through the cystic duct, which is a side branch off the common bile duct. Here, most of the fluid is removed from the bile (about 2 - 5 cups a day), leaving a few tablespoons of concentrated bile.
This need is signaled by a hormone called cholecystokinin, which is released when food enters the small intestine.
The force of the contraction propels the bile down the common bile duct and into the small intestine, where it emulsifies (breaks down) fatty molecules.
Pigment stones (black or brown) are also very common and account for the remaining 30% of stones. Although cholesterol makes up only 5% of bile, about three-fourths of the gallstones found in the US population are formed from cholesterol. If there is an imbalance between these bile salts and cholesterol, then the bile fluid turns to sludge. Bilirubin is a substance normally formed by the breakdown of hemoglobin in the red blood cells. They contain more cholesterol and calcium than black pigment stones and are more likely to occur in the bile ducts.
In most cases, common bile duct stones originally form in the gallbladder and pass into the common duct. This refers to a condition in which a person has symptoms of gallbladder stones, yet there is no evidence of stones in the gallbladder or biliary tract.
There is a very small (2%) chance of developing pain during the first 10 years after gallstones form. If it persists beyond this point, acute cholecystitis or more serious conditions may be present.


Large or fatty meals can trigger the pain, but it usually occurs several hours after eating and often awakens the patient during the night.
Conditions that may cause these symptoms include peptic ulcer, gastroesophageal reflux disease, or indigestion of unknown cause. Acute cholecystitis can progress to gangrene or perforation of the gallbladder if left untreated. This can cause pain (biliary colic), infection and inflammation (acute cholecystitis), or both. It is extremely dangerous and life threatening if it spreads to other parts of the body (a condition called septicemia), and surgery is often required. If acute cholecystitis is untreated and becomes very severe, inflammation can cause abscesses. An estimated 10% of acute cholecystitis cases result in a perforated gallbladder, which is a life-threatening condition.
In some cases, the inflamed gallbladder adheres to and perforates nearby organs, such as the small intestine. Common bile duct stones are responsible for most cases of pancreatitis (inflammation of the pancreas), a condition that can be life threatening. There is a strong association between gallbladder cancer and cholelithiasis, chronic cholecystitis, and inflammation. When the cancer is caught at an early stage and has not spread beyond the mucosa (inner lining), removing the gallbladder can cure many people with the disease. Certain conditions in the gallbladder, however, contribute to a higher-than-average risk for this cancer.
Primary sclerosing cholangitis is a rare disease that causes inflammation and scarring in the bile duct. With this rare condition, which is present at birth (congenital), the junction of the common bile duct and main pancreatic duct is located outside the wall of the small intestine and forms a long channel between the two ducts. Gallbladders are referred to as porcelain when their walls have become so calcified (covered in calcium deposits) that they look like porcelain on an x-ray.
However, only 1 - 3% of the population complains of symptoms during the course of a year, and fewer than half of these people have symptoms that return.
Pregnancy increases the risk for gallstones, and pregnant women with stones are more likely to develop symptoms than women who are not pregnant. Several large studies have shown that the use of hormone replacement therapy (HRT) doubles or triples the risk for gallstones, hospitalization for gallbladder disease, or gallbladder surgery.
Because most cases do not have symptoms, however, the rates may be underestimated in elderly men.
For example, Hispanics and Northern Europeans have a higher risk for gallstones than do people of Asian and African descent. This gene controls a cholesterol pump that transports cholesterol from the liver to the bile duct.
Studies indicate that the disease is complex and may result from the interaction between genetics and environment. Gallbladder disease may progress more rapidly in patients with diabetes, who tend to have worse infections.
Rapid weight loss or cycling (dieting and then putting weight back on) further increases cholesterol production in the liver, which results in supersaturation and an increased risk for gallstones. The risk increases proportionately with dramatic weight changes as well as with frequent weight cycling. Patients who have either Roux-en-Y or laparoscopic banding bariatric surgery are at increased risk for gallstones. Gallstone formation is associated with low levels of "good" HDL cholesterol and high triglyceride levels.
Prolonged intravenous feeding reduces the flow of bile and increases the risk for gallstones. Crohn's disease, an inflammatory bowel disorder, leads to poor reabsorption of bile salts from the digestive tract and substantially increases the risk of gallbladder disease. Chronic hemolytic anemia, including sickle cell anemia, increases the risk for pigment gallstones. High consumption of heme iron, the type of iron found in meat and seafood, has been shown to lead to gallstone formation in men. Although fats (particularly saturated fats found in meats, butter, and other animal products) have been associated with gallstone attacks, some studies have found a lower risk for gallstones in people who consume foods containing monounsaturated fats (found in olive and canola oils) or omega-3 fatty acids (found in canola, flaxseed, and fish oil). Studies suggest that people may be able to reduce their risk of gallstones by eating more nuts (peanuts and tree nuts, such as walnuts and almonds). People who eat a lot of fruits and vegetables may have a lower risk of developing symptomatic gallstones that require gallbladder removal.
Taking the medication ursodiol (also called ursodeoxycholic acid, or Actigall) during weight loss may reduce the risk for people who are very overweight and need to lose weight quickly. Irritable bowel syndrome (IBS) has some of the same symptoms as gallbladder disease, including difficulty digesting fatty foods. It is sometimes difficult to differentiate between pancreatitis and acute cholecystitis, but a correct diagnosis is critical, because treatment is very different. Elevated levels of the liver enzyme alanine aminotransferase (ALT) are helpful in identifying gallstone pancreatitis. Acute appendicitis, inflammatory bowel disease (Crohn's disease or ulcerative colitis), pneumonia, stomach ulcers, gastroesophageal reflux and hiatal hernia, viral hepatitis, kidney stones, urinary tract infections, diverticulosis or diverticulitis, pregnancy complications, and even a heart attack can potentially mimic a gallbladder attack.
Some experts recommend that the test be repeated if an ultrasound does not detect stones, but the health care provider still strongly suspects gallstones. Stones or a dilated bile duct may only be detected during ultrasound less than 50% of the time.
In an ultrasound variation called endoscopic ultrasound (EUS), the physician places an endoscope (a thin, flexible plastic tube containing a tiny camera) into the patient's mouth and down the esophagus, stomach, and then the first part of the small intestine. Computed tomography (CT) scans may be helpful if the doctor suspects complications, such as perforation, common duct stones, or other problems such as cancer in the pancreas or gallbladder. Cholescintigraphy, a nuclear imaging technique, is more sensitive than ultrasound for diagnosing acute cholecystitis. Such results are most common in alcoholic patients with liver disease or patients who are fasting or receiving all their nutrition intravenously. Endoscopic retrograde cholangiopancreatography (ERCP) was once the gold standard for detecting common bile duct stones, particularly because stones can be removed during the procedure. With the technological advancement of noninvasive imaging techniques, ERCP is now generally limited to patients who have severe cholangitis and a high likelihood of common bile ducts stones, which would need to be removed. Virtual endoscopy is an experimental technique that uses data from CT and MRI scans to generate a three-dimensional view of various body structures. Experts suggest a wait-and-see approach, which they have termed expectant management, for these patients. Gallstones almost never spontaneously disappear, except sometimes when they are formed under special circumstances, such as pregnancy or sudden weight loss. Patients with no fever or serious medical problems who show no signs of severe pain or complications and have normal laboratory tests may be discharged from the hospital with oral antibiotics and pain relievers. Patients may electively choose to have their gallbladder removed (called cholecystectomy) at their convenience. A small number of patients may be candidates for stone-breaking techniques called lithotripsy, using a laser or electric charge.
Drug therapy for gallstones is available for some patients who are unwilling to undergo surgery, or who have serious medical problems that increase the risks of surgery. The first step if there are signs of acute cholecystitis is to "rest" the gallbladder in order to reduce inflammation. These are administered if the patient shows signs of infection, including fever or an elevated white blood cell count, or in patients without such signs who do not improve after 12 - 24 hours. The most common procedure now is laparoscopy, a less invasive technique than open cholecystectomy (which involves a wide abdominal incision). Patients who have developed gallstone-associated pancreatitis almost always have a cholecystectomy during the initial hospital admission or very soon afterward. If noninvasive diagnostic tests suggest obstruction from common duct stones, the doctor will perform endoscopic retrograde cholangiopancreatography (ERCP) to confirm the diagnosis and remove stones. The procedure involves the use of an endoscope (a flexible telescope containing a miniature camera and other instruments), which is passed down the throat to the bile duct entrance. This is an approach through the abdomen, but it uses small incisions instead of one large incision. Many surgeons believe that laparoscopy is becoming safe and effective, and should be the first choice. Oral medications have lost favor with the increased use of laparoscopy, but they may still have some value in specific circumstances.
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Avoiding foods that are heavy on fat and sugar while pregnant helps reduce the risk of high blood pressure and gestational diabetes. This is a helpful tool that will give you an idea of what foods you should be consuming and which you should avoid. The only way to be sure that a product you are considering eating is fat-free and sugar-free is to check the label. Fruit juices, many canned fruits and things like fruit snacks are generally high in sugar and something to skip if you are trying to avoid sugary foods while you are pregnant.
The subjects were split into two groups, both groups were on low kilojoule anti-diabetes diets but they had very different breakfasts.
Additionally, among the big breakfast group, 31 percent of subjects were able to reduce their medication dose while none in the small breakfast group were able to do this. It is really embarrassing for women to wear short skirts or sleeveless dresses with black knees and elbows. These natural properties of the ingredients will help to get rid of black elbows and knees.
Been dealing with this problem over 20 years, this is the only product that made a difference. This thickened fluid consists of a mucus gel containing cholesterol and calcium bilirubinate. They are more likely to develop in people with hemolytic anemia (a relatively rare anemia in which red blood cells are broken down at an abnormally high rate) or cirrhosis (scarred liver).
Primary common duct stones are usually of the brown pigment type and are more likely to cause infection than secondary common duct stones.
Such inflammation usually results from reduced blood supply or an inability of the gallbladder to properly contract and empty its bile. Infection develops in about 20% of patients with acute cholecystitis, and increases the danger from this condition. Inflammation can also cause necrosis (destruction of tissue in the gallbladder), which leads to gangrene.
In general, this occurs in people who wait too long to seek help, or in people who do not respond to treatment.
The pancreatic duct, which carries digestive enzymes, joins the common bile duct right before it enters the intestine.
Symptoms of gallbladder cancer usually do not appear until the disease has reached an advanced stage and may include weight loss, anemia, recurrent vomiting, and a lump in the abdomen. Small gallbladder polyps (up to 10 mm) pose little or no risk, but large ones (greater than 15 mm) pose some risk for cancer, so the gallbladder should be removed. Porcelain gallbladders have been associated with a very high risk of cancer, although recent evidence suggests that the risk is lower than was previously thought.
Estrogen raises triglycerides, a fatty substance that increases the risk for cholesterol stones. One study of nursing home residents reported that 66% of the women and 51% of the men had gallstones. People of Asian descent who develop gallstones are most likely to have the brown pigment type. Pima women have an 80% chance of developing gallstones during their lives, and virtually all native Indian females in Chile and Peru develop gallstones. In such cases, the liver over-produces cholesterol, which is delivered into the bile and causes it to become supersaturated. For this reason, many centers request that patients undergo cholecystectomy before their bariatric procedure.
Some evidence suggests that high levels of triglycerides may impair the emptying actions of the gallbladder. Up to 40% of patients on home intravenous nutrition develop gallstones, and the risk may be higher in patients on total intravenous nutrition. Patients over age 60 and those who have had numerous bowel operations (particularly in the region where the small and large bowel meet) are at especially high risk. The complications can be so severe that some organ transplant centers require the patient's gallbladder be removed before the transplant is performed.
In addition, cholesterol-lowering drugs known as fibrates and thiazide diuretics may slightly increase the risk for gallstones. Gallstones are not associated with diets high in non-heme iron foods such as beans, lentils, and enriched grains.
Fish oil may be particularly beneficial in patients with high triglyceride levels, because it improves the emptying actions of the gallbladder. Diets that are high in carbohydrates (such as pasta and bread) can also increase risk, because carbohydrates are converted to sugar in the body. Even small amounts (1 ounce per day) have been found to reduce the risk of gallstones in women by 20%. The caffeine in coffee is thought to stimulate gallbladder contractions and lower the cholesterol concentrations in bile. Nevertheless, because gallstones are common and most cause no symptoms, simply finding stones does not necessarily explain a patient's pain, which may be caused by any number of ailments. A computed tomography (CT) scan, along with a number of laboratory tests, can determine the severity of the condition. It is the diagnostic method most frequently used to detect gallstones and is the method of choice for detecting acute cholecystitis.
Nevertheless, normal ultrasound results, along with normal bilirubin and liver enzyme tests are very accurate indications that there are no stones in the common bile duct. The tip of the endoscope contains a small ultrasound transducer, which provides "close-up" ultrasound images of the anatomy in the area. Helical (spiral) CT scanning is an advanced technique that is faster and obtains clearer images.
It is most likely to be useful in a small group of patients who have symptoms that suggest gallbladder or biliary tract problems, but whose ultrasound and other routine tests have been negative. The test has largely been replaced by ultrasound; however, it may be useful in some cases for determining the structural and functional status of the gallbladder, often before nonsurgical procedures. The images resemble those used in endoscopy (an invasive procedure), but the procedure is noninvasive. At some point, the stones may cause pain, serious complications, or both, and require treatment.
Recurrence rates are high with nonsurgical options, and the introduction of laparoscopic cholecystectomy has greatly reduced the use of nonsurgical therapies. Surgery may be done within hours to weeks after the acute episode, depending on the severity of the condition.
For gallstone pancreatitis, immediate surgery may be better than waiting up to 2 weeks after discharge, as current guidelines recommend. It is used in combination with ultrasound or a cholangiogram (an imaging technique in which a dye is injected into the bile duct and moving x-rays are used to view any stones).
Still, laparoscopy for common bile duct stones should only be performed by surgeons who are experienced in this technique.
In addition, it can help you stay within the recommended amount of weight gain while also contributing to a healthy weight baby.


In general, whole grains, fruits, vegetables, low-fat dairy and lean meats are a healthy part of a pregnancy diet.
Foods that contain fat and sugar include soda, candy, fried foods, fast food and many canned fruits in heavy syrup.
Fruit contains some sugar, but it is not recommended to completely eliminate a food group without first speaking with your doctor. Fish does contain fat, but it is the heart-healthy kind and comes highly recommended by most medical professionals.
One group had a big breakfast that contributed 33 per cent of their daily kilojoules while the other group had a small breakfast that contributed only 12.5 per cent of total daily kilojoules. By contrast, 17 percent of the small breakfast group actually increased their medication dose compared to only three percent in the big breakfast group.
But in some cases a stone may cause the gallbladder to become inflamed, resulting in pain, infection, or other serious complications. Some experts believe bilirubin may play an important role in the formation of cholesterol gallstones. If they do occur, complications usually develop from stones in the bile duct, or after surgery.
The highest risk is in men over 50 who have a history of heart disease and high levels of infection. Sometimes, in these cases, gallstones can actually pass into the small intestine, which can be very serious and requires immediate surgery. It is therefore not unusual for stones that pass through or lodge in the lower portion of the common bile duct to obstruct the pancreatic duct. Patients with polyps 10 - 15 mm have a lower risk, but they should still discuss gallbladder removal with their doctor. This condition may develop from a chronic inflammatory reaction that may actually be responsible for the cancer risk. Men who have their gallbladder removed are more likely to have severe disease and surgical complications than women.
A single gene, however, does not explain the majority of cases, so multiple genes and environmental factors play a complex role. It is suspected that the cause is lack of stimulation in the gut, because patients who also take some food by mouth have less risk of developing gallstones. However drinking other caffeinated beverages, such as soda and tea, does not seem to have the same benefit. Orlistat (Xenical), a drug for treating obesity, may protect against gallstone formation during weight loss. The risk for gallstone-associated pancreatitis is highest in older Caucasian and Hispanic women.
If possible, the patient should not eat for 6 or more hours before the test, which takes only about 15 minutes. EUS is useful and quite accurate when the health care provider suspects common bile duct stones, but they are not seen on a regular ultrasound and the patient is not clearly ill. With this process, the patient lies on a table while a donut-like, low-radiation x-ray tube rotates around the patient. For these patients, performing a MRCP can eliminate the need for ERCP and its side effects.
Some studies suggest the patient's age at diagnosis may be a factor in the possibility of future surgery.
Note: Drug treatments are generally inappropriate for patients who have acute gallbladder inflammation or common bile duct stones, because delaying or avoiding surgery could be life threatening. This technique is used along with antibiotics if infection is present in the common duct (cholangitis). In skilled centers, endoscopic (including transoral) techniques are becoming the gold standard. Since a major medical indicator of liver failure is high levels of ammonia in the bloodstream, it follows that detoxifying the liver may well be the best way to remove ammonia from the body.The liver normally receives some ammonia via the intestines, from the bacterial break-down of amino acids found in dietary protein.
Following the recommendations of the Food Guide Pyramid and eating a variety of foods ensures adequate nutrient intake while you are pregnant.
The closer to its natural form a food is, the healthier it is for you and your baby while you are pregnant. Skipping fruit altogether will deprive you and your developing baby of a huge amount of vitamins, minerals and antioxidants.
Try grilling some fish, but avoid swordfish, king mackerel, tilefish and shark, due to mercury content.
Whole grains in bread, cereal and crackers provide nutrients without large amounts of added fat and sugar and can be used to make sandwiches or a healthy snack.
The reason for the decline in symptoms after 10 years is not known, although some doctors suggest that "younger," smaller stones may be more likely to cause symptoms than larger, older ones. The risk for perforation increases with a condition called emphysematous cholecystitis, in which gas forms in the gallbladder. The condition can be life threatening, particularly if the infection spreads to other parts of the body. Either surgery or a procedure known as endoscopic sphincterotomy is required to open and drain the ducts. Polyps are often detected in this condition and have a very high likelihood of being cancerous.
The cancer risk appears to depend on the presence of specific factors, such as partial calcification involving the inner lining of the gallbladder. In general, women are probably at increased risk because estrogen stimulates the liver to remove more cholesterol from blood and divert it into the bile.
However, treatment for gallstones in this population is associated with a low risk of complications.
It should be noted, however, that even moderate alcohol intake increases the risk for breast cancer in women. The drug appears to reduce bile acids and other components involved in gallstone production.
About 25% of pancreatitis cases are severe, and the rate is much higher in people who are obese. During the procedure, the doctor can check the liver, bile ducts, and pancreas, and quickly scan the gallbladder wall for thickening (characteristic of cholecystitis).
Opioids such as morphine may have fewer adverse effects, but some doctors avoid them in gallbladder disease.
A healthy liver detoxifies that ammonia, by converting it into urea, which is then removed from the body by way of the urine.
Low-fat dairy is important for bone health for your baby and is part of a healthy pregnancy diet. Acalculous gallbladder disease will often cause symptoms similar to those of gallbladder stones.
HRT may also be a less-than-attractive option for women because studies have shown it has negative effects on the heart and increases the risk for breast cancer. Pregnant women, people who are unable to drink in moderation, and those with liver disease should not drink at all.
But, if the liver is malfunctioning, the ammonia remains unprocessed, and will enter the bloodstream.To enhance the detoxification pathways, the liver uses sulfur compounds to produce the antioxidant glutathione. This is a dangerous and misleading event, however, because peritonitis (widespread abdominal infection) develops afterward.
The amino acid L-cysteine is the most crucial sulfur compound needed by the liver to produce glutathione. The best way to get L-cysteine into the body, in supplemental form, is to use N-acetyl-cysteine. NAC is a powerful antioxidant and immune stimulant, and as well has been shown to support lung function, and to help remove heavy metals.It should be noted that taking NAC is more efficient at raising glutathione levels than taking actual glutathione, in supplement form.
Vitamin C is also a potent elevator of glutathione production, with 500mg being sufficient to create this response. Other supplements that can effectively raise glutathione levels include Milk Thistle Extract, Alpha Lipoic Acid, L-Glutamine and Whey protein. If we have consistent high blood sugar levels, it causes the kidneys to filter too much blood and, by overworking them, we reduce their filtering capacity.
High blood sugar levels can lead to reduced potassium levels in the blood, and if too much potassium is excreted it leads to alkaline urine. Urine that is too alkaline will reduce the amount of ammonia that is removed by the kidneys.Three amino acids, L-Arginine, L-Citrulline and L-Ornithine, are necessary components of the urea cycle, and are therefore believed to work as protective agents against ammonia toxicity.
They do this by stimulating urea formation, which aids the kidneys in performing their detoxification function. A larger quantity of these 2 amino acids may be taken, but remember to take them on an empty stomach.Eating celery or drinking celery juice daily will help kidney function, and also electrolyte balance.
Celery also works to removes excess uric acid from the blood, a further aid to kidney function.INTESTINAL HEALTH AND AMMONIA DETOXIFICATIONAs mentioned above, small amounts of ammonia are produced as a byproduct of the normal digestion of proteins, and the body is prepared to handle this quantity. However, parasites, bad bacteria, and candida yeast overgrowth in the intestinal tract, can produce more ammonia than the body is equipped to deal with, leading to a compromised immune system.Taking probiotics (friendly bacteria) maintains healthy bacterial flora, which in turn, reduces yeast overgrowth, and lowers the pH level of the large intestine, making it far more acidic.
When the large intestine has a high level of acidity, the ammonia produced by intestinal bacteria remains in an ionized form. In this form, it is easily dissipated from the body, without entering into general circulation through the blood, and burdening the kidneys, liver and brain.Animal studies have confirmed that probiotics can reduce levels of urea and ammonia in the blood.
The same studies also found the herb Yucca to work for reducing ammonia generation in the intestines.
It is believed that yucca may work on arthritis by correcting the balance of intestinal bacteria, eliminating bad bacteria and normalizing good bacteria, leading to a reduction in inflammation.Another beneficial supplement to fight ammonia excess is bentonite clay, which absorbs toxins out of the intestinal tract.
This clay is commonly used in programs designed to fight candida yeast overgrowth, but as well it shows an affinity for ammonia ions.
It is considered to be most effective when taken mixed into liquid, as opposed to ingesting it in capsule form.A serving of bentonite is one teaspoon of clay powder mixed into 2 oz of water (juice may be used if the water mixture is unpalatable to you) and shaken well. Then take a break, and use occasionally, or every few months as part of a detox protocol.OTHER WAYS OF REMOVING AMMONIA FROM THE BODYChlorophyll, the green pigment of plants, is a good blood cleanser, neutralizing toxins such as ammonia and carbon monoxide. Chlorophyll can be purchased as a liquid supplement, or is found in super foods, such as wheatgrass, barley grass and chlorella, which are more rich in nutrients than is chlorophyll alone.The amino acid L-Glutamine is another one of the most important nutrients that protects the brain and body from ammonia toxicity.
The importance of glutamine is indicated by the fact that it is the most abundant amino acid found in the body. The body uses extra glutamine as a source of energy for the brain, if blood sugar levels dip too low, so again, we see the importance of maintaining stable blood sugar levels.
On a more direct level, if blood levels of ammonia increase, the body uses more glutamine to reduce ammonia levels in the brain.
L-glutamine also has a well-proven ability to elevate glutathione levels, which, as we saw in the section on the liver, is also an important part of ammonia removal.Magnesium is required by the body in adequate amounts to help maintain blood sugar levels, which we have seen is important to helping the kidneys to perform their detoxification function.
Magnesium also serves a function in glutamine metabolism, by activating glutamine synthetase, an enzyme that also helps to remove ammonia from the cells.THE MEDICAL APPROACH TO REMOVING AMMONIAThe medical system uses two medicines to lower ammonia levels, when the situation is severe.
One is the antibiotic “neomycin” which acts in the colon to kill the bacteria that break down proteins. The other is the sugar lactulose which reduces the absorption of nitrogen from the intestines.
Lactulos, which is actually a laxative, also draws ammonia into the colon and then removes it though its laxative effect.
These two agents would only be used in the most serious conditions of ammonia toxicity.TESTING FOR AMMONIAThere is a medical test for high ammonia, which involves taking a blood sample from either a vein or an artery. The medical profession uses the ammonia test to help investigate the cause of changes in behavior and consciousness, to help diagnose the cause of a coma or of Reye’s syndrome, or to diagnose various liver or kidney diseases. However, this test will only determine if levels are severely high, not if levels are problematic, but not life-threatening. Another problem with this test is that brain levels of ammonia may be much higher than blood levels, something that can cause serious problems, but that will not be revealed by the blood test.AMMONIA REMOVAL IDEAS FROM THE AQUARIUMI part one I noted that fish will die quickly if there is too much ammonia present in their environment , because they have no way to detoxify it out of their bodies.
Thus, fish tanks have filters powerful enough to filter and clean the aquarium of excess ammonia.
Here the ammonia comes from the fish’s urine, and from tap water treated with ammonia (cloramine) and not neutralized by a specific liquid product, designed for this purpose (commonly available where aquarium supplies are sold).So, fish owners must test the tank’s ammonia levels regularly, to ensure that the filter is functioning well and protecting their fish.
Testing ammonia levels is a similar process to testing PH levels, but uses two solutions instead of just one. It is suggested that one do 2 or 3 ammonia tests to insure accurate results.My point here is that, if we suspect that we have ammonia in our water supply, perhaps we can use the same system to check our water as fish owners do. Any aquarium shop will sell ammonia test kits, and it is recommended that for most freshwater fish, the ammonia level should not exceed 2 ppm (parts per million).
So, if we detect levels much higher than this we know we have a problem.Aquarium owners also often add Zeolite chips to aquarium filters in order to reduce ammonia levels.
Zeolie is an absorbent porous mineral consisting mostly of silica and aluminum (a non-reactive form).
It will trap and hold ammonia and other toxins, sort of like a sponge.There are different grades of Zeolite, some of which are artificially created, but for ammonia removal we want a natural form, one which will have a high affinity for ammonia molecules. These chips are recharged by immersing them in a strong solution of non-iodized salt water, and then rinsed. If this is done, zeolite chips will last for many yearsSince, zeolite is commonly consumed as a supplement (used to remove heavy metals from the body), it should be a safe option for inexpensively filtering ammonia out of drinking water. We would just add the chips to the bottom of our water-filter pitcher at a level proportionally reduced from the level recommended for an aquarium. Some more research on your part would be required but, for example, if a certain amount is recommended for a 5 gallon tank, and your water filter contains 1 gallon, you would add one-fifth as much zeolite.CONCLUSIONSo, while there is yet another toxin to worry about, if we are diligent we can find solutions to cope with it.
And modern living now seems to be a constant back and forth between new damaging technologies and poisons (thanks to science without a conscience), and finding a suitable response that protects us, or at least undoes most of the damage. From electro-smog and radiation, to GMO foods and xenoestrogens in the environment (all initially sold to us as safe technologies), we have no choice but to stay informed and do our research, if we wish to remain healthy and ahead of the game. My blood test showed I was deficient for Asparagine which could in turn create high ammonia levels (common problems: fatigue and immune system stress).
Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota. He still works but I feel like we are headed down a path where things could be changing for the worse.
It is almost as if ammonia is dripping out of me, sometimes even leaving a burning sensation. I came to the conclusion that my body must either be producing excess ammonia during my detox, or that my body is releasing ammonia because of the detox. Once I experienced the symptoms of ammonia poisoning mentioned in your article, and it was extremely frightening. I fear for my reproductive health as a result of this and I am hesitant to detox even though I need to.
When detoxifying, yeast die-off can cause problems that would be halted by eating sugars, essentially feeding the yeast and allowing them to go back to business as usual, and stopping the die-off.
I would suggest seeing a medical profession to get tested for any type of infection, and to be aware that in Chinese medicine intense detoxification should only be done when you are relatively well since the process can be too much of a burden to those who are weak. I have been drinking liquid chlorophyll in water daily, so I was surprised at this increase of ammonia smell, unless the chlorophyll is bringing the ammonia out of my body and this is why the smell? I tried amino acid supplementation of L-Arginine, and L-Ornithine per your blog recommendation and found it helped, but still suffered from a strong residual ammonia taste in my mouth. Recently I found out about Resistant Starch (potato flour) and out of desperation decided to try it along with probiotic supplementation. It has been nothing short of miraculous in getting rid of excess ammonia and there are conclusive scientific studies about it’s capabilities in drastically reducing ammonia in the intestines. Thanks to glutamine, toxic ammonia is separated off in the kidneys and the basic ammonia molecule is connected to acids and is excreted.



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