If you look closely at the cortex and medulla, you can see many tiny, tubular structures that stretch across both regions perpendicular to the surface of the kidney.
Each part of the nephron has different types of cells with different properties -- this is important in understanding how the kidney regulates the composition of the blood.
The kidney is the only organ of the body in which two capillary beds, in series, connect arteries with veins.
Anything (fluid, ions, small molecules) that has not been reabsorbed from the lumen gets swept away to form the urine, which ultimately leaves the body. Part of the reason that we don’t get support during these times is that we don’t think it’s commendable to announce these decisions.
Around the beginning of August, I decided that I was feeling good enough to start seriously training for a running event again. Last week, I ran with my good friend (the runner who helped me create my plan) and I found myself telling her that I would have to take it easy, that I felt like I was getting sick, and that I would have to walk the hills. Chris Kresser also discusses how too much exercise (especially chronic cardio) can push the body’s stress response too far. We all know that sleep is an important piece of the puzzle for making your healthiest self.
A study done back in 2009 revealed that sleep disturbances, whether they are the inability to fall asleep at an appropriate time or waking up a lot in the night, both contribute to weight gain, obesity, and type 2 diabetes.
The impact on our bodies from a lack of proper sleep and irregular cortisol levels is huge.
So if you feel like you’ve been doing everything right- you have your diet in check, you exercise (but not too much!), your life stress is low, and life’s joys are high,yet you’re still unable to loose the weight, you may want to consider prioritizing sleep a little more. If you do think that weight loss is an appropriate, healthy goal and you’re ready to focus more on happy, healthy sleeping (can you imagine sleeping as blissfully as the adorable baby above?), there are plenty of tips to help get you on your way.
Obesity is a term that means you weigh at least 20% more than what is considered a normal weight for your own height.
Blood pressure is the force of blood pushing against the walls of the human arteries when the heart pumps blood. Your chances of suffering from high blood pressure are much greater if you are obese or overweight.
In case the clot is rather close to the brain, it could block the flow of oxygen and blood to the brain and lead to a stroke. Another one in this list of diseases caused by obese is diabetes, a disease in which the blood glucose of the body level is extremely high. Diabetes is considered as top cause of early death, stroke, CHD, blindness and kidney disease. Cancers of the breast, colons, endometrium, kidney, and esophagus are associated with obesity. Weight loss itself, ironically, especially quick weight loss, could make you prone to suffer from gallstones.
Metabolic syndrome is a name for one group of risk factors which increase your own risk for heart attacks as well as other healthA issues, like diabetes. You could suffer from any one of those risk factors by itself, yet they tend to happen together.
In addition to the above diseases caused by obesity, problems with the reproductive system are another risky disease many overweight people report.
It is said that obesity could contribute to the growth of gastric ulcers which happen when there exists an imbalance between the amount of hydrochloric acid and the enzyme pepsin. VKool encourages comments, but please remember: Play nice, keep it clean, stay on-topic, and avoid promotional content. With increasing frequency, individuals with type 1 diabetes (and, to a lesser extent, type 2 diabetes) are being placed on insulin pump therapy (also called Continuous Subcutaneous Insulin Infusion or CSII for short). One advantage of insulin pump therapy (compared to giving yourself multiple daily injections of insulin) is that you will likely achieve better blood glucose control with fewer elevated readings and fewere episodes of hypoglycemia. Pumps help avoid inconsistencies in glucose control caused by erratic absorption of typical insulin injections (especially with NPH insulin).
I find that many people who advise me they would like to switch to pump therapy are checking their blood sugars two or three times per day and are not on an optimized, intensive insulin schedule and believe that changing to a pump will, in and of itself improve and stabilize their blood sugar readings. The bottom line: If you are on intensified therapy and don't have the blood glucose control that you should, or if you are tired of giving insulin injections four or more times per day, do yourself a favour and consider switching to a pump. If you are a pump wearer and are looking for accessories (like pants with a hidden pocket to hold your pump), these can be very hard to find. If you can’t get a copy of that directly from above, then just email me and I will be happy to send you one! Enter your email address to subscribe to this blog and receive notifications of new posts by email. Type 2 Diabetes is a result from insulin resistance, a condition which cells fail to use insulin properly. If you have a family history of diabetes, it is recommended that you undergo glucose tests every 3 months. This entry was posted in Diabetes and tagged insulin resistance, Type 2 Diabetes, type 2 diabetes symptoms.
All forms of diabetes have been treatable since insulin became available in 1921, and type 2 diabetes may be controlled with medications. 5 Factors That Determine Photography PricesProfessional photographers have different ways of charging for their services. Why Can't I Lose Weight?You ask yourself "Why can't I lose weight?" Think about it for a moment. How To Lose Stomach Fat – Eat Certain Foods And Avoid The RestIf you are trying to lose stomach fat, you must learn what type of foods you can and can not eat. Treatment Of Yeast InfectionHave you just found out that you have a yeast infection and you are wanting to get rid of it?
Educational Toys For BabiesKeeping your baby entertained is a lot of fun but yet it can be challenging at the same time.
This arrangement is important for maintaining a constant blood flow through and around the nephron despite fluctuations in systemic blood pressure. Through these processes, the blood is maintained with the proper composition, and excess or unwanted substances are removed from the blood into the urine.
Why should we get praise for deciding not to do that thing that is so impressive and awesome? My nutrition was perfectly in check, and I even created my own energy bites for running and electrolyte sports drink.
So I didn’t need to look very far to find information from him about 8 Signs you are Overtraining. You’re primarily an endurance athlete, and you feel overly fatigued, sluggish, and useless. The body releases cortisol when it’s under stress, so being in a state of overtraining can lead to consistently high cortisol levels, which causes a myriad of problems, such as sleep issues, digestive, weight gain, depression, and even memory problems.
Well, it was only yesterday that I was able to admit to myself that I could be overdoing it. We’ve all experienced sleepless nights, whether it’s from staying out too late with friends, getting caught up in work until wee hours of the morning, or getting woken up in the night from a child or sick pet.


And what can we do to ensure that our sleep is helping out with our waist lines and health goals?
A huge part of the reasoning behind this comes down to how your circadian rhythm affects your cortisol levels, and then how wacky cortisol levels contribute to weight gain.
As the graph above shows, a normal and natural cortisol rhythm should be such that your cortisol rises first thing in the morning, then gradually lowers and tapers off throughout the rest of the day. Both cortisol and insulin are considered to be “major hormones” and their roles in the body are very important. Of course this comes after really thinking about whether it’s necessary or even healthy to try to loose weight.
I won’t go into lots of detail here on what those specific changes are since that would be a whole other blog post.
If this pressure increases and keeps staying high for a long period of time, it could damage the human body in different ways. Oftentimes, the human body breaks down the consumed food into glucose and then carries it to the cells throughout the body. According to some studies, it is shown that there is a connection between obesity and cancers of the ovaries, gallbladder, and pancreas. Reducing weight at a rate of about 1 pound per week tends to be less likely to result in gallstones.
If you are obese or overweight, you might be at the higher risk of having abnormal blood fats.
Sleep apneaA might also result in daytime sleepiness and make stroke and heart disease more likely. Excessive weight could result in injury in the most vulnerable parts of your spine that carry the weight of the whole body.
These areas could turn into irritated from the sweating and rubbing, resulting in skin infections. Check yourself and drop your words below this post to let us know your thoughts about this topic. A huge additional benefit is that the great majority of people with diabetes who go on pump therapy LOVE it and would NEVER go back to conventional injections. Sure, that may sound unpleasant, BUT I must say that these words are seldom spoken by actual pump users; it's pretty well only people that haven't yet tried a pump who voice this concern.
For most people with type 1 diabetes - and for many people with type 2 diabetes - it is simply better therapy. In addition to telling you your glucose level (updated every 5 minutes) at any given time, there are also alarms to let you know if you are high or low (especially helpful if you are prone to bad overnight lows) and arrows to tell you if your glucose level is heading up or down.
Insulin and some oral medications can cause hypoglycemia (low blood sugars), which can be dangerous if severe. There are endless amounts of Facebook status updates announcing the decision to start training for a marathon, to be a part of some challenge, or to take on a new project at work or at home.
Well, I think that it’s often very difficult to do what’s truly right for oneself, especially when that’s taking a step back and being honest with what actions are and are not helpful to your life.
I love the dedication, focus and commitment that goes along with deciding upon a goal and following the path to train for it.
My runs started feeling easier, I started to feel faster, and I even started enjoying waking up early. The following day, I was supposed to run another five miles, so I set out to do so at Discovery Park, but less than a mile in I had to stop to walk.
Since I already know that I have an autoimmune condition and tend towards adrenal fatigue, this is certainly all true for me.
I texted my husband after what was supposed to be a 7 mile trail run that turned into a snail’s pace of a 4 miler, and told him what I thought was happening. I booked a massage appointment with the voucher I’ve been holding onto for just the right occasion. But for now, I’m publically announcing that I’m taking a step back from doing something awesome.
Basically, having a proper circadian rhythm helps your cortisol levels stay where they should be. It will increase a bit with each meal, but should overall be lowering until bedtime, when it should be at it’s lowest point. And not only were people wanting to eat more, but the reward centers in their brains were more active for junk food. A healthy body should be “insulin sensitive”, meaning it can release insulin in just the right amounts for what the body needs after digesting food.
In our culture we tend to assume that weight loss is usually an acceptable goal, since obesity rates are so high, and our social media honors thinness. But check out this great post as well as this one , oh and especially this one, (after you finish this post of course!) and you’ll be on your way. Nevertheless, overtime, the human body could not make adequate insulin to take control of its blood glucose level. Actually, these contain high levels of triglycerides and bad cholesterol (LDL) and low levels of good cholesterol (HDL). As the spine has to carry the excess weight, the chances of suffering from the spinal injury or structural damage enhance. Switching to a pump does NOT, just by virtue of being on a pump, make things better any more than driving a Porsche rather than a Hyundai makes you a better driver. This system measures your glucose level under the skin surface (typically, of your abdomen) using a tiny probe that you insert and leave in place for a few days.
It's a long, thin tube that is closed at one end, has two twisted regions interspaced with a long hairpin loop, ends in a long straight portion and is surrounded by capillaries. I think that it can actually be relatively easy to decide to do something big and impressive, since you get all the support behind you to help you accomplish that. I decided that a 20 mile trail run was my goal, and found one in the area at the end of October. Then, around the middle of September, I started noticing that it was harder to get out the door for my runs. Almost all of them rang true for me, and this means that if I’m going to be honest with what’s best for myself, I need to take a step back from my training.
In fact, high stress (in this case it was physical stress) can cause hypothyroidism to worsen a lot as well, and I certainly have noticed my symptoms around that increase over the past few weeks. I told him that I was disappointed but that it’s probably best if I take a step back with my training.
It doesn’t just make us feel tired, it also can make us cranky and irritable, give us terrible sugar cravings, make us want to eat more in general, remove our self control, feel unable to concentrate, and promote weight gain.
If your rhythm is like this, you should feel awake and ready to start the day in the morning, alert throughout the day, then sleepy at night. It’s much harder to make good decisions about food when we’re sleep deprived, since our impulse control is limited.
When a body becomes insulin resistant, the fat cells become less sensitive to insulin, which causes high blood sugar, therefor making them more susceptible to obesity and diabetes. But I will say that I think that the most critical part in being able to successfully prioritize sleep is just that- making it a priority.


Indeed, many (but most definitely not all) people with poor control can achieve excellent control WITHOUT a pump if they monitor their blood sugars four or more times per day and are given expert and ongoing instruction about intensified insulin management. Your glucose level is then displayed on a pager-size device you wear (or, if you are using a certain type of pump, the result is displayed right on the pump) and, basically, gives you a continuous readout of where your glucose levels are at.
Pancreas transplants have been tried with limited success in type 1 DM; gastric bypass surgery has been successful in many with morbid obesity and type 2 DM. But it can be hard to be honest with yourself about whether or not that big, impressive thing really is doing you good, and if it isn’t, to stop doing it.
I found a training plan and consulted with a good friend who’s a crazy ultrarunner and made a few tweaks to make it just right. I felt much more tired in the mornings, and constantly felt like I needed to go to bed earlier.
He responded by telling me how great it is that I’m listening to my body and making changes. Unfortunately, in today’s world, we are more stressed out than is natural or healthy, so our body is releasing too much cortisol too often in order to deal with these stresses. Since your circadian rhythm directly influences your cortisol levels, if you don’t feel this way, I would recommend looking into natural ways to get back to your natural circadian rhythm.
In fact, studies even show that areas in the frontal lobe of the brain (the area which governs impulse control) were diminished after bad night’s sleep. In fact, being at a healthy weight is especially important for fertility, and there’s no room for being too thin or undernourished.
It may sound obvious, but it’s usually a lot harder than it sounds, so it takes some focus. It is better for you to lose from 10 to 15 pounds to help reduce the risk of develop those problems. Deciding that what’s best for you physically is to take a break from training for that marathon. I told a few friends what I was doing, with the condition that I would train for and do the race as long as I felt good.
I didn’t feel like it was great at the time, but now that I’ve had some time to think on it, I realize how hard it was for me to allow myself to see the truth and decide to do something about it. I’m trying to reduce cortisol levels through acupuncture, my silly at home yoga moves, and meditating.
This causes cortisol levels that are irregular, and unfortunately after awhile of this high cortisol output, it can cause adrenal fatigue.
A few basic things to concentrate on would be to expose yourself to natural daylight when you want your cortisol levels up (first thing in the morning) and avoiding artificial light when you want them to be low. This means that a lack of proper sleep can affect you at a cellular level- your fat cells are actually unable to respond to insulin properly. Even if weight loss is a good goal, focusing solely on weight loss rather than other health related goals, and being unhappy with yourself until you attain your weight loss goal can be very unhealthy.
Our busy culture tends to honor those who can get away with less sleep (or who think they can), somehow thinking they’re more productive and therefor more honorable.
Being honest with yourself when you realize that being a part of another challenge is distracting you from your real purpose or goals.
I knew that burning myself out over completing a race would be a bad idea for my health, but that it’s easy for me to get caught up in the excitement of fitness and goal setting. This last weekend, despite planning on taking a day off of running, my husband and I found a new trail that we decided to test out.
An unnatural, broken cortisol rhythm, whether it’s become adrenal fatigue or not, affects your body in many negative ways.
For example, video games and television at night not only amp up brains but also disrupt the natural hormonal release of melatonin along with lowering cortisol, which is meant to help with sleepiness. Lastly, sleep deprived people tend to loose as much lean mass weight as fat mass when calorie restricting for weight loss purposes, which is not good. And unfortunately, it can take only one night of bad sleep for your body to become insulin resistant. I definitely urge you to keep a positive mindset about yourself and your body even if you do want to loose weight for healthy reasons. I doubt that those who sleep less are more productive- at least in the long term they aren’t since at some point they will likely crash and burn. Realizing that taking on another project at work will take away from time spent with your family, and that that’s not worth it to you.
I was planning on doing a 15 miler one of the first mornings I’m there, but we’ll see if I’m feeling up for that or not. Most relatively and importantly for this conversation is that it makes it very difficult for your body to burn fat for fuel, it increases the rate of storing fat, makes you crave sugar, and raises your blood sugar levels. Eating and exercising at appropriate times (when you want your cortisol levels raised) will also help regulate your levels.
There are many studies backing up this claim that sleep debt has a harmful impact on carbohydrate metabolism, and therefor weight gain. They do not monitor your blood glucose levels and they do not figure out on their own how much insulin to give you.
I was able to get out on real trails at least three times a week, which was not only good for my training, but also for myself mentally and emotionally. I was not loosing weight like I should have been, in fact I gained a little around my waist, despite logging in more miles. Either way, I will definitely be enjoying early mornings moving on the beach in some way or another.
All this equates to weight gain, or at least a much harder time loosing weight, if that’s your goal.
And while productivity is what we’re all seeking, I definitely don’t think that being more outwardly productive makes someone more honorable.
In the evening, when you want your circadian rhythm lowering, avoid those stimulating things such as light, food, and exercise. I just don’t think that doing more necessarily (and usually doesn’t) equate to you being more. During my runs, I would have to stop to walk more often than normal, and any incline felt like a major struggle. There are more extensive tips on how to get back on track, but I find that the summer is the perfect time to simplify it all and do your best at structuring your sleep around the natural cycles of light. It’s the time for our bodies to become restored, to detox, and help us to focus better when we are awake and active. Although I had lots of signs and symptoms, it took me a couple of weeks to pay attention and really acknowledge it. So, if you want to, make it a priority, make a few changes, and see what happens to both your health and your waistline!



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Comments

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