As reported in ScienceDaily, a diet high in fructose increases the risk of developing high blood pressure (hypertension), according to a paper being presented at the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition in San Diego, California. Over the last 200 years, the rate of fructose intake has directly paralleled the increasing rate of obesity, which has increased sharply in the last 20 years since the introduction of HFCS.
Diana Jalal, MD (University of Colorado Denver Health Sciences Center), and her colleagues studied the issue in a large representative population of US adults.
Additional studies are needed to see if low fructose diets can normalize blood pressure and prevent the development of hypertension. High fructose corn syrup (HFCS) is a liquid sweetener used in the manufacture of foods and beverages. Despite the similarity, there is growing evidence that High Fructose Corn Syryp can disrupt the body's metabolism and bring about a syndrome called "insulin resistance" and type 2 diabetes. Insulin resistance is a condition in which the body does not effectively use the insulin it produces. American consumes nearly 70 lb (32 kg) of HFCS a year, marking HFCS as a major contributor to the rising rates of obesity in the last generation. High fructose corn syrup has been linked in many clinical trials to the obesity epidemic in the U.S. Although many factors contribute to the obesity epidemic in the United States, no other culprit has been as highly criticized as high fructose corn syrup (HFCS). In fact, high fructose corn syrup has been linked in many clinical trials to the obesity epidemic in the U.S.
However, part of what makes HFCS such an unhealthy additive to any diet is that it is metabolized into fat in the body far faster than any other type of sugar. Since most high fructose corn syrup is consumed in liquid form (often in sugary sodas), its negative metabolic effects are significantly increased.
HFCS contains no enzymes, vitamins or minerals, and sucks all available micronutrients from the body. Bottom line: Stay away from high fructose corn syrup and the dangers that will inevitably follow. Natural sources of fructose include fruits, some vegetables, honey, sugar cane and sugar beets. Pure fructose contains no enzymes, vitamins or minerals and robs the body of its micronutrient treasures in order to assimilate itself for physiological use. While naturally occurring sugars, as well as sucrose, contain fructose bound to other sugars, high fructose corn syrup contains a good deal of "free" or unbound fructose.
Lysl oxidase is a copper-dependent enzyme that participates in the formation of collagen and elastin.
In humans, fructose feeding leads to mineral losses, especially higher fecal excretions of iron and magnesium, than did subjects fed sucrose. According to government health officials, not only do the American Indian and Alaska Native populations suffer have the highest diabetes rates among ethnic groups, but the disease is increasing in the young American Indian population. A program that has established diabetes prevention and treatment programs in Indian country is set to expire next year.
A possible hint at culture or diet as a factor can be seen in the statistics for culturally diverse New York City. Even though commonly consumed sugars provide basically the same number of calories, they are metabolized and used by the body in different ways. According to the Unternational Food Information Council, "There is no scientific proof of cause and effect with respect to the consumption of HFCS rather than other sugars, such as sucrose, regarding obesity rates.


Fructose is a simple sugar, unique in that it does not require the body to make insulin in order to use the sugar as fuel. A look at the growing obese population in countries where HFCS is in "everything" seems to indicate that it does just that. Diabetes is a lifelong disease characterized by high levels of the sugar glucose in the blood. Gestational diabetes occurs when a woman without obvious diabetes develops high blood sugar during pregnancy.
There is a lot women with gestational diabetes can do to maintain good health through pregnancy and minimize complications. The findings suggest that cutting back on processed foods and beverages that contain high fructose corn syrup (HFCS) may help prevent hypertension. Today, Americans consume 30% more fructose than 20 years ago and up to four times more than 100 years ago, when obesity rates were less than 5%. Jalal's team found that people who ate or drank more than 74 grams per day of fructose (2.5 sugary soft drinks per day) increased their risk of developing hypertension. The body compensates by producing greater amounts of insulin in order to maintain normal blood glucose levels.
The effects often result in diabetes, obesity, metabolic syndrome, an increase in triglycerides and LDL (bad) cholesterol levels, and liver disease. Meira Fields and her coworkers at the US Department of Agriculture investigated the harmful effects of dietary sugar on rats. Fructose seems to interfere with copper metabolism to such an extent that collagen and elastin cannot form in growing animals--hence the hypertrophy of the heart and liver in young males.
Iron, magnesium, calcium, and zinc balances tended to be more negative during the fructose-feeding period as compared to balances during the sucrose-feeding period.According to a recent article in the American Journal for Clinical Nutrition, high fructose corn syrup (HFCS) is the possible culprit for the obesity epidemic in America. The disease increased 77 percent among young people younger than 15 during the same time frame. For instance, glucose from dietary sources is digested, absorbed, transported to the liver, and released into the general blood stream.
Some studies suggest we are consuming more calories, but the imbalance of calories consumed and expended is what has caused the weight increase -- we consume more calories than we need."Is this true? Ingesting fructose does produce that "sugar rush" when the body is pumping insulin to the bloodstream. High blood sugar is caused by the body’s inability to make insulin or respond to insulin normallyGlucose comes from food and is the main energy source for the body.Insulin is the hormone produced by the pancreas that is responsible for telling organs such as the liver, muscle, and fat to remove glucose from the blood. This typically happens late in pregnancy, around 28 weeks or later.Gestational diabetes places the mother and baby at risk pregnancy complications such as macrosomia (largebaby), pre-eclampsia (high blood pressure) and birth injury. Percent increase in the odds of each complication was adjusted for potential confounders including, but not limited to, maternal age, BMI, height, smoking status, and family history of diabetes. Healthy meal planning, physical activity, and blood sugar monitoring are important parts of managing gestational diabetes. This panel of tests can be performed during the first and second trimester to screen for gestational diabetes risk before diagnosis is typically made. While this increase mirrors the dramatic rise in the prevalence of hypertension, studies have been inconsistent in linking excess fructose in the diet to hypertension.
Fructose intake was calculated based on a dietary questionnaire, and foods such as fruit juices, soft drinks, bakery products, and candy were included. Insulin resistance -- along with obesity, hypertension, and blood lipid disorders -- is part of the metabolic syndrome.


The Corn Refiners Association has fought back against those claims by insisting that HFCS is no worse for the body than regular sugar. They discovered that when male rats are fed a diet deficient in copper, with sucrose as the carbohydrate, they develop severe pathologies of vital organs.
Fields repeated her experiments to determine whether it was the glucose or fructose moiety that caused the harmful effects. HFCS, which has been linked to diseases such as obesity, type 2 diabetes, cardiovascular disease and breast cancer among others, is a prevalent ingredient in foods and beverages through-out the country. Many tissues take up glucose from the blood to use for energy; this process requires insulin. Even with all the chemistry and processing, HFCS is still the cheapest way to sweeten food. This bodily sensation is often connected with your feeling of "satisfaction" or "fullness." After ingesting fructose you may not feel satisfied -- even though your caloric intake is the same as sucrose.
Findings from the National Health and Nutrition Examination Survey (2003-2006)," (TH-FC037) was presented as part of a Free Communications Session during the American Society of Nephrology's 42nd Annual Meeting and Scientific Exposition on Oct. When there is not enough insulin, or these organs can’t respond to insulin, less glucose gets into cells to be stored for energy. In fact, 80 – 90% of women with gestational diabetes can be managed with lifestyle therapy alone. Identification of gestational diabetes risk allows women to make lifestyle changes earlier to improve health and wellness throughout pregnancy. The most common form in the American food supply is HFCS-55, which contains 55% fructose and 45% glucose. Today, the inclusion of fructose in virtually every food product dramatically increases the proportion of fructose in our diet. Liver, heart and testes exhibit extreme swelling, while the pancreas atrophies, invariably leading to death of the rats before maturity. In studies with rats, fructose consistently produces higher kidney calcium concentrations than glucose. Fructose is predominantly metabolized in the liver, but unlike glucose it does not require insulin to be used by the body. It's also said to extend the shelf-life of products and easier to mix because it's a liquid. Women with blood sugar levels that cannot be controlled with lifestyle changes will require insulin injections.
Some researchers have suspected that the health problems linked to HFCS stems from the unusually high consumption of fructose, the main ingredient in HFCS.
On a copper-deficient diet, the male rats showed some signs of copper deficiency, but not the gross abnormalities of vital organs that occur in rats on the sucrose diet.
Fructose generally induces greater urinary concentrations of phosphorus and magnesium and lowered urinary pH compared with glucose.
Whites who are not Hispanic have the lowest rate -- 5 percent -- and Asians are second to last, with 6.8 percent. Over the past 20 years, as methods for producing HFCS improved, food and beverage companies have all replaced other sweeteners with HFCS.



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