A blood glucose test measures the amount of a type of sugar, called glucose, in your blood. A new study published in The Journal of Biological Chemistry claims to have identified a potential driver of type 2 diabetes: vitamin A deficiency.
The researchers, from the Weill Cornell Medical College in New York, NY say that their findings may lead to new treatments for the condition, including consumption of yogurt which is a good source of vitamin A.
Past studies have shown that, during fetal development, vitamin A is key for beta cell production. What is more, when the researchers removed vitamin A from the diets of healthy mice, they found that this led to significant beta cell loss, resulting in reduced insulin production and increased blood glucose levels – key factors involved in development of type 2 diabetes.


This findings suggest vitamin A may have the potential to reverse type 2 diabetes and could partly explain how yogurt may reduce the risk of type 2 diabetes by as much as 28%.
When the researchers restored vitamin A to the rodents’ diets, beta cell production rose, insulin production increased and blood glucose levels returned to normal.
Blood sugar chart shows the fasting and post prandial values for a normal person, for a person with early and established diabetes.
Lorraine Gudas, vitamin A boosts beta cell activity, meaning lack of the vitamin may play a role in the development of type 2 diabetes. Gudas and colleagues say it was unclear as to whether vitamin A played such a role in adulthood.


To find out, the team analysed the beta cell development among two groups of adult mice; one group of mice had been genetically modified to be unable to store dietary vitamin A, while the other group was able to store the vitamin from foods as normal.
Hypoglycemia, also known as low blood sugar or low blood glucose, is when blood sugar decreases to below normal. The researchers found that the mice unable to store vitamin A experienced beta cell death, meaning these mice were unable to produce insulin.



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Comments

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