| City | Population | Rank | Cost of Living Rank | Crime Rate Rank | High School Graduation Rate Rank | Median Household Income Rank | Median Home Value Rank | Median Rent Price Rank | Employment Rate Rank | Big Deal Score | 
| Waukee | 15,931 | 1 | 60 | 13 | 7 | 4 | 4 | 21 | 16 | 17.86 | 
| North Liberty | 14,485 | 2 | 77 | 2 | 7 | 13 | 19 | 4 | 6 | 18.29 | 
| Grimes | 9,040 | 3 | 80 | 3 | 7 | 2 | 1 | 1 | 47 | 20.14 | 
| Johnston | 18,728 | 3 | 60 | 9 | 2 | 5 | 13 | 5 | 47 | 20.14 | 
| Clive | 16,220 | 5 | 75 | 5 | 1 | 1 | 2 | 12 | 47 | 20.43 | 
| Norwalk | 9,411 | 6 | 48 | 14 | 12 | 8 | 17 | 15 | 32 | 20.86 | 
| Ankeny | 49,080 | 7 | 60 | 18 | 2 | 6 | 10 | 9 | 47 | 21.71 | 
| Urbandale | 41,020 | 8 | 70 | 22 | 2 | 3 | 3 | 6 | 47 | 21.86 | 
| Pleasant Hill | 9,009 | 9 | 65 | 35 | 13 | 7 | 8 | 3 | 47 | 25.43 | 
| Coralville | 19,692 | 10 | 79 | 51 | 2 | 22 | 6 | 13 | 6 | 25.57 | 
| Waverly | 10,035 | 11 | 48 | 46 | 24 | 18 | 23 | 19 | 4 | 26 | 
| Indianola | 14,947 | 12 | 41 | 34 | 19 | 17 | 20 | 22 | 32 | 26.43 | 
| Cedar Falls | 39,993 | 13 | 53 | 21 | 13 | 27 | 18 | 18 | 37 | 26.71 | 
| West Des Moines | 59,296 | 14 | 70 | 60 | 2 | 10 | 5 | 2 | 47 | 28 | 
| Bettendorf | 34,255 | 15 | 65 | 11 | 17 | 11 | 9 | 20 | 71 | 29.14 | 
| Eldridge | 5,903 | 15 | 65 | 23 | 13 | 9 | 12 | 11 | 71 | 29.14 | 
| Iowa City | 70,133 | 17 | 80 | 47 | 7 | 52 | 7 | 8 | 6 | 29.57 | 
| Pella | 10,397 | 18 | 53 | 28 | 63 | 14 | 13 | 7 | 30 | 29.71 | 
| Marion | 35,843 | 19 | 70 | 10 | 17 | 15 | 22 | 34 | 42 | 30 | 
| Nevada | 6,754 | 20 | 41 | 58 | 24 | 19 | 33 | 30 | 10 | 30.71 | 
| Grinnell | 9,118 | 21 | 19 | 27 | 36 | 33 | 37 | 44 | 20 | 30.86 | 
| Altoona | 15,409 | 22 | 53 | 62 | 13 | 12 | 15 | 16 | 47 | 31.14 | 
| Ames | 60,634 | 23 | 70 | 55 | 7 | 56 | 11 | 10 | 10 | 31.29 | 
| Sioux Center | 7,210 | 24 | 75 | 20 | 69 | 16 | 16 | 24 | 1 | 31.57 | 
| Hiawatha | 7,135 | 25 | 60 | 7 | 20 | 26 | 34 | 37 | 42 | 32.29 | 
| Carroll | 10,017 | 26 | 32 | 17 | 36 | 32 | 31 | 76 | 6 | 32.86 | 
| Orange City | 6,155 | 27 | 70 | 6 | 46 | 23 | 25 | 62 | 1 | 33.29 | 
| Harlan | 5,085 | 28 | 19 | 33 | 36 | 61 | 42 | 39 | 4 | 33.43 | 
| Independence | 5,967 | 29 | 19 | 30 | 31 | 29 | 39 | 50 | 37 | 33.57 | 
| Washington | 7,326 | 30 | 60 | 31 | 36 | 30 | 45 | 27 | 20 | 35.57 | 
| Boone | 12,546 | 31 | 37 | 61 | 22 | 35 | 40 | 46 | 18 | 37 | 
| Decorah | 8,109 | 32 | 77 | 15 | 36 | 36 | 21 | 60 | 15 | 37.14 | 
| Denison | 8,387 | 33 | 9 | 1 | 80 | 38 | 47 | 74 | 12 | 37.29 | 
| De Witt | 5,285 | 34 | 41 | 26 | 22 | 25 | 26 | 58 | 64 | 37.43 | 
| Dubuque | 58,155 | 35 | 48 | 57 | 36 | 39 | 30 | 32 | 25 | 38.14 | 
| Algona | 5,509 | 36 | 65 | 68 | 20 | 24 | 28 | 23 | 42 | 38.57 | 
| Cedar Rapids | 128,119 | 36 | 9 | 4 | 57 | 62 | 58 | 77 | 3 | 38.57 | 
| Glenwood | 5,232 | 38 | 41 | 65 | 79 | 20 | 27 | 25 | 14 | 38.71 | 
| Le Mars | 9,795 | 39 | 65 | 41 | 31 | 21 | 32 | 57 | 25 | 38.86 | 
| Creston | 7,874 | 40 | 9 | 38 | 27 | 73 | 69 | 41 | 32 | 41.29 | 
| Knoxville | 7,296 | 41 | 9 | 44 | 57 | 47 | 54 | 52 | 30 | 41.86 | 
| Manchester | 5,123 | 42 | 41 | 25 | 36 | 44 | 53 | 75 | 20 | 42 | 
| Waterloo | 68,297 | 43 | 19 | 64 | 46 | 54 | 46 | 29 | 37 | 42.14 | 
| Vinton | 5,203 | 44 | 53 | 37 | 31 | 41 | 42 | 56 | 37 | 42.43 | 
| Clear Lake | 7,741 | 45 | 37 | 56 | 27 | 28 | 24 | 67 | 59 | 42.57 | 
| Council Bluffs | 62,115 | 46 | 37 | 81 | 66 | 42 | 38 | 14 | 23 | 43 | 
| Des Moines | 206,688 | 47 | 32 | 79 | 57 | 37 | 35 | 17 | 47 | 43.43 | 
| Winterset | 5,181 | 48 | 32 | 58 | 57 | 57 | 29 | 38 | 36 | 43.86 | 
| Newton | 15,108 | 49 | 16 | 52 | 27 | 60 | 48 | 34 | 74 | 44.43 | 
| Anamosa | 5,625 | 50 | 48 | 19 | 57 | 48 | 50 | 51 | 42 | 45 |