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25.04.2016 admin
Researchers are launching a Phase 2 clinical trial to make sure the impressive mesothelioma survival rates they achieved earlier with a novel photodynamic therapy-enhancing drug were no fluke. If the drug continues to prove itself in the course of Phase 2 testing, researchers say it could change the way doctors now think about treating mesothelioma. The clinical trial is being conducted by scientists from the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Roswell Park Cancer Institute. The first of 102 patients stricken by the epithelioid form of malignant pleural mesothelioma have already enrolled in the clinical trial. In late 2011, the FDA granted orphan drug status to PHOTOFRIN? as an adjuvant therapy for malignant pleural mesothelioma surgery. Photodynamic therapy with PHOTOFRIN? is a targeted treatment that attacks tumor cells but avoids causing permanent damage to healthy neighboring tissues.
In the clinical trial, photodynamic therapy with PHOTOFRIN? is being tested as method of mopping up mesothelioma cells that surgery leaves behind.
Proponents of radical pleurectomy say the procedure is designed to save a mesothelioma patient’s lung. However, while the mesothelioma cells that remain after surgery are few, they almost always manage to quickly reestablish themselves.


In an attempt to prevent this from happening to the enrollees, they will receive doses of PHOTOFRIN? a full day before surgery.
After the surgery is completed but before closing up the chest, they each will then be treated with photodynamic therapy.
Cengel explains that the clinical trial seeks in part to determine why this photodynamic therapy strategy works well against mesothelioma.
He says he also has his fingers crossed that it will establish a new treatment path for mesothelioma patients — patients that currently have so few existing options. ABOUT USMesotheliomaClinic.org is the place to come if you’re serious about understanding this disease and want to improve your chances of survival. Like Us On FacebookMesothelioma Clinic 4 days ago Patients in their 70s may find #mesothelioma surgery worth considering.
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Lay 24” (60cm) pieces of strong twine or cord across the bags every three or four courses and every 24” (60cm) horizontally along the wall.


Enter your email address to subscribe to this blog and receive notifications of new posts by email. Food and Drug Administration in 2004 approved PHOTOFRIN? — under orphan drug rules — for treatment of cholangiocarcinoma, a rare cancer that develops in the bile ducts. If the surgery is successful, it can improve the patient’s survival outlook and quality of life. Cengel — an associate professor and director of photodynamic therapy at Perelman — says the treatment methodology appears promising.
One group will receive photodynamic therapy during surgery, plus postoperative standard chemotherapy.
We stand right beside you in this showdown with mesothelioma, one of the most cruel and vicious killers on earth.
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