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Polycystic ovary syndrome (PCOS) is a hormonal disorder that affects as many as 10% of women of childbearing age.Clear Passage is a world leader with over two decades of experience treating female infertility without surgery or drugs. Over the last 20 years, clinical trials showed significant improvement in hormone levels after therapy, while published peer-reviewed medical journal citations noted that our therapy improved fertility for most women. As the name “polycystic” suggests, many cysts typically develop in the ovaries of a woman with this condition. Thus, hormonal problems (poor maturation) develop into mechanical problems (ovarian walls thicken and eggs become trapped in the ovary).Successful reproductive activity depends on a medically recognized communication loop between the ovaries (in the pelvis) and the pituitary and hypothalamus glands (deep inside the head). While physicians recognize that a communication loop occurs among the pituitary, hypothalamus and the ovaries, the exact mechanism of that communication remains a mystery.
However, we have come to question that assumption as more and more women we treat with PCOS show positive – sometimes remarkable – hormonal changes. Physicians may offer two surgical options to help eggs escape from the thickened ovarian walls.
During the course of therapy, we treat the full body as we focus in on dura and all of its attachments, from the tailbone into the head. To date, the results of our research treating hormonal conditions in women has been overwhelmingly positive. Ovulation induction involves the use of medication to stimulate development of one or more mature follicles (where eggs develop) in the ovaries of women who have anovulation and infertility. Some of the women with anovulation have a condition known as PCOS or polycystic ovarian syndrome. Ovulation induction is somewhat different from controlled ovarian hyperstimulation which involves use of some of the same medications to stimulate development of multiple mature follicles and eggs in order to increase pregnancy rates with various infertility treatments.
Women, such as those with PCOS, who do not ovulate on their own regularly, and want to get pregnant.
For women with ovarian failure or extremely very poor quality eggs there is not currently any drug available to allow a reasonable chance of conception with any type of ovarian stimulation.
Success rates for induction of ovulation vary considerably and depend on the age of the woman, the type of medication used, whether there are other infertility factors present in the couple, and other factors.
Metformin (brand name Glucophage) is an oral medication that has been used over the past several years by some infertility physicians to assist in inducing ovulation in some women with anovulation and polycystic ovaries.
Injectable fertility medications, called gonadotropins, contain follicle stimulating hormone (FSH) which causes development of one or multiple follicles when injected into women that do not ovulate.
These medications are given by intramuscular injections or subcutaneous injections on a daily basis.
This type of therapy is usually tried for 3-6 months and if it does not result in a pregnancy in vitro fertilization should be considered.
Ultrasound and blood monitoring of the stimulation cycle is essential when using injectable gonadotropins as there are substantial risks associated with overstimulation if the ovaries should over respond to the medication. This monitoring is usually done 3 times a week during the time the woman is taking the injectable medications. Complications associated with use of these medications include the possibility of overstimulation, called ovarian hyperstimulation syndrome, or OHSS.

In very rare cases, 9 or more fetuses have implanted and shown heartbeat activity on ultrasound studies. The risk of multiple pregnancy increases with the number of mature follicles that are seen on ultrasound examination of the ovaries. When many mature follicles develop the couple and the physician can have a discussion about the risks of multiple pregnancy and there is always the option of canceling the cycle by not giving the injection that causes ovulation.
Anovulation caused by elevated levels of the piuitary hormone hormone prolactin can be treated with a medication called bromocriptine. The costs associated with induction of ovulation depend on the type and dose of medication required and the number of ultrasound and blood tests (if any) required to adequately monitor the cycle. A cycle using injectable gonadotropins usually costs between $1500 and about $6000, depending on what is done and how much injectable fertility medication the woman needs to stimulate follicle development.
In a landmark 10-year study treating infertile women, our non-surgical therapy yielded pregnancy rates for women infertile with PCOS at much higher rates than standard medical treatments (see chart below). Complete the online Request Consultation form to receive a free phone consultation with an expert therapist and learn more.
These cysts or follicles (fluid filled sacs) contain eggs; but in women with PCOS, the ovary does not produce enough hormones for egg maturation. This interplay among glands, called the hypothalamic-pituitary-ovarian axis, is largely responsible for whether or not a woman’s eggs can reach maturity during the process of reproduction. We initially thought that we could not affect hormone levels; we assumed that the communication was based on blood chemistry, or neurological in nature, and had nothing to do with the biomechanics of bodily structures. This sheath surrounds the central nervous system, responsible for a myriad of complex activities and commands. We now encourage women with some hormonal conditions, including PCOS, endometriosis, amenorrhea (no menstrual cycle) and high FSH levels to apply for treatment.
These women do not regularly develop mature follicles without help from ovulation enhancing drugs. Treatment with these drugs has the potential to result in pregnancy if the woman has good quality eggs remaining in her ovaries, and if other causes of infertility are not present. Egg donation is the only realistic option for getting pregnant with premature ovarian failure.
The injections are started early in the menstrual cycle and are continued for approximately 8-14 days until one or more mature follicles are seen with ultrasound examination of the ovaries. Pregnancy rates per month are better than those with use of Clomid and for relatively young women with no other contributing causes to the infertility pregnancy rates per month of approximately 15% can be expected when this form of treatment is combined with intrauterine insemination.
In general approximately 75% are single, 20% are twins, 5% are triplets and 1% are quadruplets or higher. Rarely can a pregnancy of more than 5 fetuses result in viable live birth unless a fetal reduction procedure (selective abortion) is performed at about 11-13 weeks of pregnancy.
However, it is often not possible to stimulate the patient so that only one mature follicle develops and multiple follicle development is usually the rule. This essentially eliminates the risk of any pregnancy (single or multiple) occurring in that cycle.

Sometimes artificial insemination will also be recommended which increases the chances for a pregnancy, as well as the cost of the cycle.
Unable to escape, the follicles or cysts remain and build up in the ovaries, preventing ovulation.
Due to the very positive results we have documented and published about our patients with PCOS and other hormone-related infertility, we believe there is a strong mechanical mechanism in the body’s hormone systems – at least for female infertility. With the results published in our landmark 10-year infertility study showing success rates up to four times the success rates of medical treatment, we are getting scientific support for these theories. In ovarian wedging, the doctor removes a wedge of the ovary, like cutting out a slice of pie.We believe our success with women with hormonal disorders is due in large part to our work at the major attachments of the dura.
Any adhesive restriction within that system can create profound effects in various areas of the body. At that point an injection of HCG is given which induces ovulation to occur approximately 36 hours later. Pregnancy rates with injectable gonadotropins combined with intercourse are somewhat lower.
The required dose ranges from about 75 units per day to 375 or more units per day for about 7-14 days. Some health insurance plans will pay for the entire cost of ovulation induction including insemination if that is desired. Hyperstimulation involves enlarged ovaries, abdominal pain, and fluid build-up within the abdomen. Immature follicles may remain in the ovary and ovarian walls may thicken.Polycystic ovary syndrome (PCOS), a hormonal disorder that often affects ovulation, is the most common cause of female infertility. In addition, the ovaries tend to produce excess levels of androgens (male hormones) in women with PCOS, which can also negatively impact ovulation and fertility. The dura is a fascial sweater that surrounds the spinal cord, from the bottom of the tailbone at the coccyx to attachments at the top of the neck and the base of the skull.
Other health insurance plans will pay for some (or none) of the costs associated with this treatment. From there, it enters the skull through a large opening (the foramen magnum), then spreads out to surround the brain and every structure in the head. Carefully monitored use of injectable gonadotropins can almost always avoid severe overstimulation. Naturally, this includes the sphenoid bone, which houses the pituitary-hypothalamus complex.

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