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10.05.2014, admin  
Category: Nutrition Plan

Asafa Powell of Jamaica was barred from competition after testing positive for the stimulant oxilofrine.
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Oxilofrine, also known as methylsynephrine or p-hydroxyephedrine, can stimulate the heart and is useful in some medical situations, such as enhancing heart function in patients under anesthesia, says Pieter Cohen, a general internist with the Cambridge Health Alliance, assistant professor at Harvard Medical School, and an author of the study. In this special report, you’ll learn about these two high-performing products, Xtreme Nitro and Alpha F1. But it's not supposed to be in dietary supplements, which are sold over the counter and which by law are supposed to consist of "dietary ingredients." Cohen, who frequently conducts research on supplements, started looking into oxilofrine after several high-profile athletes tested positive for the drug.
Asafa Powell, a Jamaican sprinter, blamed a supplement for a positive test that led to him withdrawing from the 2013 World Championships. When Cohen and his colleagues ran lab tests on 27 supplement brands with methylsynephrine on the labels, they found oxilofrine in 14 of them.
One contained more than twice the usual adult dose and three times the usual adolescent dose, the study found. The health effects of that kind of dose aren't known, but research on lower doses suggests users might experience adverse effects including heart palpitations, arrhythmias and increased blood pressure, the study says.
The FDA, meantime, has received 47 reports of adverse events associated with oxilofrine-containing supplements, though it can't say whether or not the supplements caused harm, says Steven Tave, acting director of the FDA's Office of Dietary Supplement Programs. The agency doesn't review supplements for safety and efficacy before they come to market, the way it does with drugs. The FDA took action against manufacturers because oxilofrine doesn't meet the definition of a dietary ingredient. In addition, researchers tested only for oxilofrine, and not for other stimulants that might be in the supplement. His group represents supplement makers, but he says the companies warned by the FDA are not members of his association.

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