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28.04.2016, admin  
Category: Abs Exercise For Men

Use of Ibuprofen can cause many long-term side effects on kidney, like all non-steroidal anti-inflammatory drugs (NSAID) class. Ibuprofen is the most commonly used pain reliever drug which works by decreasing the prostaglandin secretion.
Ibuprofen is an over the counter pain reliever drug which comes under the category of non-steroidal anti-inflammatory drugs (NSAIDs). In the body, excessive prostaglandin secretion is responsible for pain, swelling, and fever. Long term side effects are very rare but ibuprofen can cause kidney disease particularly in at-risk patients as reported in the scientific literature. Elder people or those individuals who have pre-existing kidney disease, heart or liver dysfunction, diuretic or ACE inhibitor users or impairment in kidney are at greatest risk for ibuprofen-induced renal side effects. A single dose of ibuprofen is also responsible for sudden-onset acute kidney failure if the patient suffers from chronic kidney disease or lupus, or drinks a lot of alcohol. Long-term use of ibuprofen and other NSAIDs cause kidney damage called as analgesic nephropathy.
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Read about Ibuprofen and several long term side effects of this pain reliever drug on kidney.


The Food and Drug Administration (FDA) approved this drug as a safe non-steroidal anti-inflammatory in 1974. Ibuprofen is a generic drug which works by blocking the enzyme in body that involves in the production of prostaglandins.
Ibuprofen mostly affects two organ systems of the body: the renal (kidneys) and gastrointestinal (GI) systems. For acute renal failure due to ibuprofen, independent risk factors also include advanced age and childhood. Analgesic nephropathy takes place in approximately four out of 100,000 people, primarily from self-medication. Further kidney damage can be prevented by treating the symptoms of existing damage such as hypertension and urine protein. Studies have found that seven days of treatment with ibuprofen considerably reduces the filtration rate of blood in infant’s kidneys. Users describe what the crystal meth high is like as similar to cocaine, only lasting for a longer period of time.
Thus, drug users can experience a severe “crash” or physical and mental breakdown after the effects of the drugs wear off. Primarily, it is used to treat mild to moderate pain such as headaches, muscle aches, backaches, dental pain, menstrual cramps, arthritis, and athletic injuries for the relief of everyday.
Kidney damage is resulted from the chronic ingestion of NSAIDs and it is usually reversible in many cases.
Long-term use of non-steroidal anti-inflammatory, ibuprofen has resulted in renal papillary necrosis and other kidney impairment, as per the “PDR Guide to Drug Interactions, Side Effects, and Indications”.


Aside from damage to the kidneys, it also alters the sodium and water balance which is regulated by the kidney, having profound consequences in hot training and racing environments. Patients with reduced kidney function are not recommended to take ibuprofen, as warned by the National Kidney Foundation. There is an almost instant euphoria, followed by an increase in energy and alertness that can last for up to 12 hours. Also, it is used to decrease fever and to relieve minor aches and pain due to common ailments and diseases like osteoarthritis and rheumatoid arthritis. Like all non-steroidal anti-inflammatory drugs, ibuprofen use has also several potential side effects. Patients who have taken six or more pills per day for more than three years are on greater risk for the analgesic nephropathy. Presently, ibuprofen is sold under the names Motrin, Advil, Medipren, Nuprin and others, which relieves pain and swelling (inflammation).
As per FDA, it is safe to use but some mild side effects have been proven to exist after a year or long term use.
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