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One of the reasons we started Citadel Nutrition was because we were tired of proprietary blends. Another key benefit of Tier 1 is that it is equal parts energy boost and performance supplement. Every batch of Tier 1 is tested by an independent testing agency to verify label claims and ensure safety and effectiveness.
One of our biggest challenges before starting Citadel Nutrition was trying to get test results from companies. Supplementing with creatine increases your intramuscular stores of phosphocreatine, which allows your body to resynthesize an energy source in your body called ATP.
Simple terms – creatine increases performance during high intensity activities that require short bursts of energy like weight lifting and sprinting as well as activities that require a mix of short bouts and steady state energy.
Creatine is probably the single most studied dietary supplement with hundreds of studies showing a positive performance benefit.
The most important thing is to make sure you’re getting a daily maintenance dose once loaded.
Although creatine has no acute affects, we wanted Tier 1 to give the added value of providing a maintenance dose of creatine on training days. Supplementing with beta-alanine increases intramuscular carnosine levels which helps reduce fatigue. Beta-alanine is another widely researched performance increasing supplement with 20 plus studies showing a positive performance benefit.
If you examine the numerous studies of beta-alanine you’ll find that the majority administered it in divided doses. Effects of 28 days of beta-alanine supplementation and creatine monohydrate supplementation on aerobic power, ventilatory and lactate thresholds, and time to exhaustion.
Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Effects of beta-alanine supplementation on the onset of neuromuscular fatigue and ventilatory threshold in women. Although there are not numerous studies examining its effect when paired just with caffeine – from an expert review and empirical evidence standpoint its use when paired with caffeine is well supported. We generally recommend mixing Tier 1 in 4-6 oz of water, stirring, and taking 15-45 minutes prior to working out. Do I need to stress out if I miss a day or three of supplementing with creatine on off-days? No, the goal is to increase the skeletal  muscle levels of carnosine in and keep them elevated. Although there are no long term studies on the use of beta-alanine, it is a naturally occurring non-essential amino acid produced in the body and generally regarded as safe.

Stimulates your central nervous system, increases alertness, improves focus, combats sleepiness.
In theory, stopping caffeine for a period of time will make it work more effectively; in practice however, it can be difficult to do due to negative effects such as headaches and performance decrease. Tyrosine is a precursor substrate for adrenaline, noradrenaline, and dopamine in the brain (catecholamines). If you have questions, comments, or just want to chat supplements, go to our Contact Us page.
Fat is probably the least important macronutrient where preworkout nutrition is concerned.
Tier 1 gives you the added benefit of taking a maintenance dose of the two MOST scientifically proven performance ingredients out there. A key benefit of Tier 1 is that you know exactly what's in the bottle and how much of each ingredient you're taking. It gives you the added convenience of taking a daily maintenance dose of the two MOST scientifically proven performance ingredients available. Ultimately this company started because we were scratching our own itch and it is a fundamental principle we follow. Back to the principle of creating supplements we take ourselves – we like the convenience of having it in our preworkout on training days instead of taking it separately.
From an energy, alertness, focus, and just combating sleepiness perspective I think most of us have a pretty good understanding of what caffeine does. It is worthy to note that these position stands are not the end all be all (Alan Aragon exposed many deficiencies on their nutrient timing stand in the October 2008 RR) but we felt that it was a pretty good summary of the research available on caffeine and also consistent with what we’ve read elsewhere. Due to that recommendation, the fact that tyrosine is in the mix, and the differing sensitivities to caffeine – we decided on 200mg.
So Tyrosine is a precursor substrate for adrenaline, noradrenaline, and dopamine in the brain (catecholamines). We relied heavily on research by Lyle Mcdonald in his Stubborn Fat Loss, Ultimate Diet 2.0, and specifically the Protein Book when including and dosing this ingredient.
Many of the full text studies are available but for some of the others you have to pay $25 to $30 for the full text. We recommend cycling caffeine use in order to "reset" your system so to speak and obtain maximum ergogenic benefit. You have the right to know and it's also the only way you can verify that you're getting an effective dose. It was also the base for our homemade mix years ago and those that "get it" will know why they're in the mix. They take into consideration like scientific validity, study design, mechanisms of action, etc.

We included it in Tier 1 because it is another widely researched performance enhancing ingredient, second only to creatine in terms of the number of studies showing positive benefit.
We love it – we find that it gives us the extra boost to train with the intensity we like.
It is worthwhile to note that it is impossible to formulate a preworkout dosed perfectly for every individual. It would be a disservice to try to say that there is a link and only post the studies showing a benefit. The common recommendation from the literature we’ve read is 1-3 grams of l-tyrosine with 200mg of caffeine. An example cycling period would be to cease all caffeine use for 1-2 weeks every couple months.
Simply put, Creatine and Beta-Alanine don't have acute performance effects but if you're an athlete you'll benefit from their use.
There is a loading period, similar to creatine, with beta-alanine and it can take up to a month of supplementation to increase skeletal muscle levels of carnosine to the point of seeing a performance increase.
The 275lb man may require a different dose of caffeine than the 150lb man, and factors such as caffeine use and sensitivity to stimulants may also come into play. This is touched on in the ISSN position stand and also in the June 2011 AA Research Review.
As far as we could tell, Tyrosine by itself does not appear to have any major impact on sports performance. The reason it is in the mix is because empirical evidence suggests that it works synergistically with caffeine. Although we can’t send you the full text we can cite specific sections or answer any questions you may have. Whether that’s the case is up for some serious debate, but that’s a topic for another article. Simply put – it has an impact as a pre-workout stimulant when combined with caffeine. In this article, we’ll break down pre-workout nutrition that will prime you for growth!
Since tyrosine can increase catecholamine production and caffeine can increase catecholamine release – these two compounds should work together to increase the energy effect.

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