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The good news is that, unlike many of the slimming pills you can buy at your local health store, Xenical and Reductil are both clinically proven to help people lose weight and generally receive the support of most health professionals.
This entry was posted in Dieting Strategies and tagged dietary, good, loss, supplements, weight. Dietary Supplements to Help Promote Weight LossReviewed by Nutricula on Jun 28Rating: With at least two-thirds of the nation being overweight, effective approaches to promoting weight loss is an absolute health necessity. Dietary Supplements to Help Promote Weight LossReviewed by Nutricula on Jun 28Rating: With at least two-thirds of the nation being overweight, effective approaches to promoting weight loss is an absolute health necessity. In 1994, researchers discovered that genetically obese mice were lacking a heretofore unknown hormone called leptin. If a person gets too fat, the extra fat produces more leptin which signals an area of the brain in the hypothalamus to stop being hungry, to stop eating, to stop storing fat and to start “burning” off some extra fat. At first, scientists thought that administering leptin might also be the cure for human obesity. Another consideration is that adipose tissue functions to some extent as an endocrine organ, secreting  several adipokines including a small protein called adiponectin.  Adiponectin plays an important role in regulating weight by increasing fatty acid oxidation. High viscosity polysaccharides are derived from acacia gum, and esterified fatty acids are from flax seed.
In an 8-week placebo-controlled, double-blind study consisting of a moderately caloric restricted diet and cardiovascular exercise (30-60 minutes daily), the high viscosity polysaccharides and esterified fatty acids were given to 20 overweight women. A fair amount of research has been conducted which demonstrates the value of green tea in supporting and promoting weight loss. Treatment with caffeine in amounts equivalent to those found in the green tea extract had no effect on EE and RQ. In a 12-week, randomized, double-blind, controlled clinical trial, 132 overweight adults were randomly assigned to receive a beverage containing approximately 214 mg of EGCGs with 39 mg caffeine or a control beverage (39 mg caffeine, no catechins). In a 3-month, open study, 70 overweight men and women, 20 to 69 years of age, received two capsules, twice daily of green tea extract standardized at 25% catechins expressed as EGCG (270 mg EGCG per day). In a randomized placebo-controlled double blind parallel trial, 76 overweight subjects  matched for sex, age, BMI, height, body mass, and habitual caffeine intake were put on a very low calorie diet for four weeks (weight loss period or WL), followed by three months of weight maintenance (WM).  During the WM period, the subjects received a green tea-caffeine mixture (270 mg epigallocatechin gallate and 150 mg caffeine per day) or a placebo. The results (see table below) were that the green tea group experienced a statistically significant loss in body weight (-2.7 kg or about 6 lbs) at the end of 12 weeks compared to baseline.
The authors of the study concluded that green tea can reduce body weight in overweight Thai subjects by increasing energy expenditure and fat oxidation.
A systematic review and meta-analysis of 15 randomized controlled trials (RCTs) (n = 1243 patients) of green tea catechins (GTCs) (including those trials with and without caffeine) on anthropometric variables, including body mass index (BMI), body weight, waist circumference (WC), and waist-to-hip ratio (WHR) was conducted. Results indicate that GTCs with caffeine decreased BMI, body weight, and WC but not WHR compared with caffeine alone.
The authors concluded that the administration of GTCs with caffeine is associated with modest, but statistically significant, reductions in BMI, body weight, and WC. Phytosome technology creates intermolecular bonding between individual polyphenol molecules and one or more molecules of the phospholipid, phosphatidylcholine (PC).

This was demonstrated in a study during which human volunteers were supplemented with single doses of green tea polyphenol catechins in free or phytosome form.
In a multicenter clinical trial, 100 overweight subjects of both genders were place on a hypocaloric diet (about 1,850 and 1,350 kcal daily for men and women, respectively). After 90 days of treatment, significant weight loss and decreased body mass index (BMI) were observed in the group taking the green tea phytosome (30-lb loss in the green tea group compared to an 11-lb loss in the diet-only group). The authors concluded that the high safety profile of the product and the total absence of adverse effects observed during and after the trial suggests that green tea phytosome is a safe and effective tool for weight loss.
The amino acid L-carnitine is most concentrated in tissues that use fatty acids as their primary dietary fuel, such as skeletal and cardiac (heart) muscle.
In short, L-carnitine is required for mitochondrial beta-oxidation of long-chain fatty acids for energy production. In total, these facts provide a convincing case for the use of supplementary use of L-carnitine as an adjunct to an effective approach for weight management. Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, Friedman JM.
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Using the food diary and tools in WLR can help you lose weight without pills, and can provide the low calorie, low fat diet that most slimming pill manufacturers recommend.
While the need to incorporate a program of dietary modification and exercise is well-established, adjunct support using evidence-based dietary supplements may improve the effectiveness and speed of overall success.
Furthermore, adiponectin production may, at least in part, be controlled by the hypothalamic actions of leptin. High viscosity polysaccharides have been shown to significantly reduce appetite and food intake more effectively in humans than medium viscosity polysaccharides (glucomannan) or low viscosity polysaccharides (cellulose).  Together with esterified fatty acids, this complex has been shown to lower leptin, signaling to the body to use both stored and dietary fat as energy. The results were that the women experienced a 92% improvement over placebo in lowering body fat and a 62% improvement in reducing waist circumference (see graph). The placebo group also lost weight, but the amount was not statistically significant compared to baseline. GTC ingestion with caffeine also significantly decreased body weight when compared with a caffeine-free control.
Molecular imaging suggests that PC molecule(s) enwrap each polyphenol; upon oral intake the amphipathic PC molecules likely usher the polyphenol through the intestinal epithelial cell outer membrane, subsequently accessing the bloodstream.
Besides the effect on weight and BMI, biochemical parameters (LDL-, HDL-, and total cholesterol, triglycerides, growth hormone, insulin-like growth factor-1, insulin, and cortisol) were favorable in both groups. In this regard, L-carnitine plays an important role in energy production by chaperoning activated fatty acids (acyl-CoA) into the mitochondrial matrix to be metabolized.
The difference in weight loss between the two groups were statistically significant (p=0.046). Endocrine regulation of energy metabolism: Review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin and resistin.

Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults.
Body Weight Loss and Weight Maintenance in Relation to Habitual Caffeine Intake and Green Tea Supplementation. Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial.
Effect of green tea catechins with or without caffeine on anthropometric measures: a systematic review and meta-analysis.
Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts. Greenselect Phytosome as an adjunct to a low-calorie diet for treatment of obesity: a clinical trial. Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. All content posted on this site is commentary or opinion and is protected under Free Speech. The improvement in body composition and percent of body fat is achieved through the interaction between the adipose tissue, brain and liver to reduce serum leptin. In addition, leptin levels were lowered by 42%, and adiponectin levels were increased by 53%. 107 participants completed the study.  The results were a trend toward greater loss of body weight in the catechin group compared with the control group.
The results were that green tea catechins were absorbed more extensively when administered as phytosome rather than as free catechins.
No differences between frequency and type of side effects were observed between the placebo and supplement groups, so the high viscosity polysaccharides and esterified fatty acids supplement appears to be both effective and safe. Oz is also known to alert viewers to the occasional nutritional supplement that is reported to burn fat, but not always clearly substantiated with credible research or adequately presented with contraindications and warnings that should be addressed for some consumers. In the high caffeine consumers, no additional effects of the green tea-caffeine mixture were observed during WM. 105348 - Nutrilite^ Slimmetry Dietary Supplement Weight Loss Supplements - Women s Health Boost your weight loss efforts in the gym and in the kitchen with a little help from Mother Nature.
In addition, catechin also promoted healthy fasting serum triglycerides (TG) levels already within a healthy range. Here s a rundown of the 3 best natural weight loss products: 1 The best rapid weight loss diet pills supplements that Over-the-counter dietary supplements to treat obesity appeal to many patients who desire a magic bullet for weight loss.
These findings suggest that green tea catechin consumption enhances exercise-induced changes in abdominal fat and serum TG.

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