A blood blister is a kind of blister that develops when tissues and blood vessels in the dermis are damaged without the epidermis getting pierced.
Blood blisters usually develop because of a sudden intense force such as hard pinching of the skin rather than gradual application of friction that causes ordinary blisters. If your blister gets punctured, make sure to keep the flap of skin above the raw area intact since this serves as its protection. When you first see a blister on your skin, first thing that you must not do is to break the blister. You should secure the band aid in such a way that it does not touch the blister. You should also not tightly wrap the band aid so that it slashes off the blood supply from the area.
If you see blister in a area where too much of pressure is applied like the foot, then it is better that you put a doughnut shaped mole skin pad around the blister to protect it from breaking due to high pressure. Home treatment for blister helps to alleviate the blister pain; prevent blister infection or helps in healing huge unbroken blisters.
If you want to drain such large blisters clean a thin needle with soap or alcohol, and gently puncture the edge of the blister. It is not advisable to tear the skin flap of the drained blister unless you see dirty pus or any kind of infection under the skin.  Even if you see a small crack in the blister skin, slowly smooth it evenly over the skin.

You also should not use alcohol or iodine over the blister as it delays the healing process of the skin.  Following the application of the ointment over the blister, you can freely tie a band aid around the area.
One important thing that you have to be wary about is that during blister healing you have to prevent any kind of skin infection. Thus, bodily fluids like lymph and blood get trapped underneath the outermost layer of the skin.
Blood blisters on the feet are often cause by footwear that are uncomfortable and don’t fit properly hence causing pressure. Keeping it dry will definitely reduce the risk of the separation of skin layers and blisters forming.
However, if your blisters often recur and appear to have infections, then you should seek the help of a doctor. The area over the blister should be open.  It is also advisable to avoid shoes that rub with the blister. The first step in home treating the blister is to first wash your hands with soap to prevent infection when you touch the blister. Unlike other blisters, blood blisters contain all of the components of blood along with hemoglobin, which gives it its characteristic dark red color.

The use of moleskin on the area frequently chafed will prevent blood blisters from developing.
It is recommended to leave the blister uncovered unless something strikes against the blister. First, you have to understand that very large blisters will break on its own and heal quickly if it is left undisturbed.
The ointment not only disinfects the blister but also prevents the band aid from gluing to the skin.
Excessive and continuous friction, such as that caused by raking or shoveling for a long period of time, may also cause blood blisters to manifest.
Another way by which you can prevent blood blisters is through the use of protective gear such as gloves. If you suspect that something would rub, then you have to apply an unfastened band aid around the blister.

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