Plantar Warts immediately after treatment they initally will turn a slight yellowish color. There are many ways to remove plantar warts, such as acid, laser treatment, cryotherapy,curettage and desiccation,oral medication or immunotherapy. 4 treatments to Remove Plantar Warts for Ankle Pain Most of the time, plantar warts can be painful. Comparison of the use of standardized diagnostic criteria and intuitive clinical diagnosis in the diagnosis of common viral warts (verrucae vulgaris). Intralesional injection of mumps or Candida skin test antigens: a novel immunotherapy for warts. Comparison of combination of cimetidine and levamisole with cimetidine alone in the treatment of recalcitrant warts.
Self-administered topical 5% imiquimod for the treatment of common warts and molluscum contagiosum. In the case of warts, the agent responsible is human papillomavirus (HPV), of which there are more than 150 serotypes.11 Some are known to cause cervical cancer, but common warts that affect nongenital skin are not thought to have malignant potential.
It is presumed that inoculation of the skin probably occurs in places likely to be contaminated by others with plantar warts, like communal showers.

With the exception of cervical lesions, determining the serotype of a wart is not clinically useful. The virus that causes warts, the human papillomavirus, infects only the superficial layer of skin, producing a thickened callus-like growth that, if located in an areas subjected to pressure, can become quite tender. Warts result from a hyperkeratotic reaction to human papillomavirus infection; nongenital warts are classified as common, periungual, flat, filiform, or plantar, based on location and shape. Warts are treated by local destruction (acids, cryotherapy, electrodesiccation-curettage), chemotherapy, or immunotherapy.
Multiple warts are common and are spread by skin-to-skin contact or contact with a contaminated surface. Molluscum contagiosum (MC) and warts are benign epidermal eruptions that result from viral infections of the skin. As with other warts on the hands and feet, they often show peeling and roughening of the surface and tend to be somewhat abraded although not as much as palmar warts.
Because of the forces exerted on the foot, plantar warts tend to become callused and grow into the foot instead of rising above the plantar surface. Plantar warts can be differentiated from a corn or callus by paring down the surface (Figure 11).

Patients have to soak the wart in water for five to 10 minutes before each application (daily for liquids, every 48 hours for patches), then debride the dead skin after each application.Bi- and trichloroacetic acids are applied in the physician's office on a weekly basis, usually after paring down the wart. The dead tissue also may generate an immune system reaction to help resolve additional warts. Chemotherapy may be useful at a designated wart clinic, where several patients can be treated from the same vial of bleomycin in a single day. It is commonly used for plantar warts.ImmunotherapyHPV infection does not disappear once the gross lesions are destroyed. Candida antigen can be used on most verrucae, particularly plantar warts.Cimetidine (Tagamet) is known to stimulate T-lymphocyte populations, which are important in controlling viral infections.
At a dosage of 30 to 40 mg per kg per day, it has been tried with varying success in the treatment of warts. It may be useful in non-genital HPV, but more study is needed.9Topical application of sensitizing agents such as diphenylcyclopropenone, dinitrochlorobenzene, and squaric acid causes an allergic contact reaction that has been used for treatment of warts, but these chemicals are not commonly stocked by family physicians.

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