This is a type of eczema, which is a skin condition, will frequently cause multiple blisters on hands that can cause pain and itch at the same time. When having this medical condition you can develop small blisters with red borders and white centers that are painful on the palms of your hands. This is a chronic skin condition that can cause itchy blisters on the palms of your hands and the sides of your fingers that are normally red and scaly. The best treatment for blisters on hands it to leave them alone and do nothing and try to not put any pressure on the blisters while it is healing naturally. You should apply an antibiotic ointment to the open blisters and cover with gauze or bandage.
Gently wash the blisters on hands with hydrogen peroxide or sterilized water and pat the area dry with done. There is no specific treatment for these blisters and normally the infection that is causing these blisters of hands will resolve itself within a week or less.

To help these blisters on hands heal you should use compresses that have been soaked in Burrow’s solution or potassium permanganate.
If the blisters on hands have not healed within four days you should see your physician because sometimes blisters on hands can be an indication of other illnesses and diseases like chicken pox, eczema, herpes, etc. Before discussing what can be the causes of blisters on hands it is important that you know what a blister is. If you have certain medical condition like diabetes, you should let your physician check it out to make sure that there are no complications from the blisters. You should keep it wrapped to help protect the blisters on hands from accidentally being popped and if they are popped the bandage or gauze you have wrapped around it will help to prevent something from getting into the opened blister. This type of blister is hard to self-treat so you should contact a dermatologist to make an accurate diagnosis of whether it is or is not Dyshidrosis.
You should then cover it very loosely with a piece of sterile gauze or bandage so bacteria cannot enter the blister.

When you see your physician or dermatologist they may give you antibiotics or use light therapy on the blisters to help them heal and to help prevent infections.
When you pop a blister the lower layers of your skin are exposed to the elements having an infection most likely to develop. If the blister does need to be popped it should be done by your physician under conditions that are sterile in order to prevent an infection from setting in.

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