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06.01.2016

Clear warts on toes,dr. soler puerto rico,how to use dr scholl's corn and callus remover - Easy Way

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Therapies and Treatment StrategiesReferencesCutaneous warts are a common presenting complaint in children and adolescents. Therapies and Treatment StrategiesReferencesTreating warts is a therapeutic challenge for family physicians.
Immunotherapy for recalcitrant warts in children using intralesional mumps or Candida antigens. An assessment of methods of treating viral warts by comparative treatment trials based on a standard design. Pulseddye laser versus conventional therapy in the treatment of warts: a prospective randomized trial. Intralesional injection of mumps or Candida skin test antigens: a novel immunotherapy for warts. Intralesional immunotherapy for nongenital cutaneous warts may be an option for large or recalcitrant warts. Although RCTs are lacking, imiquimod has demonstrated potential efficacy in the treatment of recalcitrant nongenital warts.


In a study19 using imiquimod, cure rates of 88.9 percent were observed for recalcitrant nongenital warts in children when applied twice daily. One review6 based on non-randomized historical cohort comparisons supported the use of imiquimod as first-line therapy for treatment of flat warts. Another review,4 however, found insufficient evidence to support the use of imiquimod for treatment of cutaneous nongenital warts.BLEOMYCINBleomycin (Blenoxane), a chemotherapeutic agent, inhibits DNA synthesis in cells and viruses.
Bleomycin is an alternative therapy for warts that have not responded to other therapies or warts that may be difficult to surgically excise.
A clearance rate of 92 percent was observed.23Although the number of RCTs that demonstrate the efficacy of bleomycin is low, one review4 has concluded that there is fair evidence to support its use for recalcitrant hand and plantar warts. The Cochrane review5 states that there is no consistent evidence for the effectiveness of intralesional bleomycin for treatment of nongenital cutaneous warts, and the data could not be meaningfully pooled for analysis. A dose of 1 mg per kg per day of etretinate was given for no more than three months.25 Of the 20 children involved in the study, 16 demonstrated complete clearance of their warts without relapse.
Warts recurred in four patients following partial regression.25One review4 found fair evidence supporting the use of topical retinoids based on one cohort study that examined the effectiveness of topical retinoids using a number of case reports and a limited number of trials of systemic retinoids.


Another review6 of several case studies recommended oral and topical retinoids as second-line therapy for the treatment of flat warts.INTRALESIONAL IMMUNOTHERAPYIntralesional immunotherapy employs the ability of the immune system to recognize certain viral and fungal antigens. It is believed that the delayed-type hypersensitivity reaction induced by these antigens increases the ability of the immune system to recognize and clear HPV. One study3 demonstrated complete resolution of warts in 47 percent of the participants and 75 to 99 percent resolution in 13 percent of the participants. An initial study26 examined the clearance rates for the mumps and Candida antigens separately compared with cryotherapy (mumps antigen has been discontinued).



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