The exact cause of this disease is not known, but it is believed to be caused due to hereditary and environmental factors. The white blood cells contain T lymphocyte which is responsible for fighting and destroying foreign particles on the body. For people with long-term psoriasis, they are likely to develop inflammatory bowel problems, blood pressure, diabetics and even heart disease.
Your physician will easily diagnose the disease on physical examination of the affected skin. For mild form of plaque psoriasis you need not have to visit the clinic since it can be treated effectively by over the counter medications.
Creams or ointments that contain salicylic acid or coal tar are used for treating mild forms of sunburns and psoriasis.
Any type of topical creams should be applied only after gently removing the scales or silvery patches on the skin. The main purpose of treatment is to stop the production of T cells that induces to form several new skin cells and to remove the scaly patches from the skin. Creams that contain corticosteroids are effective in reducing inflammation and hence prescribed for controlling mild to moderate type of psoriasis.
Calcipotriene cream contains vitamin D analogues for slowing down the growth of new skin cells. Topical retinoid like Tazorac Avage is given for controlling skin damage which would reduce DNA activity of skin cells but it is sensitive to sunlight.
Sometimes, a combination of UV therapy and coal tar therapy is given which is called Goeckerman therapy. Retinoid, corticosteroid, methotrexate are given orally or through intravenous injection for severe form of psoriasis. In addition, cyclosporine is given by doctors for weakening the immune system that destroys healthy skin cells.
It is difficult to prevent plaque psoriasis but people who are prone to this disease should not expose the skin to factors like sunlight or traumatic condition which would trigger psoriasis. New York NYC Crime Bronx Brooklyn Manhattan Queens Education Weather Obituaries Sports Yankees Mets Giants Jets Knicks Nets Rangers Islanders Football Basketball Baseball Hockey Soccer College High School The Score More Sports News Crime U.S. Follow Us Facebook Twitter Instagram Pinterest YouTube Subscribe Follow UsNewsletter App Subscriptions Subscribe Get Our Newsletter A daily blend of the most need-to-know Daily News stories, delivered right to your inbox. Select Sport Football Basketball Baseball Hockey Soccer College High School More Sports Health Homes Food Share This facebook Tweet email Prescription drug prices expected to drop heavily as drug patents expire Prescription drug prices expected to drop heavily as drug patents expire BY Associated Press Monday, July 25, 2011, 2:52 PM facebook Tweet email The change is expected to help many patients who skip certain dosing days to cut costs of pricy drugs. Usually portrayed as a T-Rex,these monsters will always show up on the recent boosters, no matter if the game is centering more on summoning creatures from the Extra Deck. He can turn into a 3000 creature on the first attack, so he won’t have any problem or limited targets on the next battles, as long we can tribute another monster for give him the boost when he has his default ATK, turning into a solid 2800 ATK and no need to activate the tributing effect, except for rare or emergency occasions.
Certain types of mutated genes are inherited by birth causing this skin condition as the child grows.
But in people affected with psoriasis, these T cells affect and kills the healthy skin cells causing wound and infection on the skin, leading to plaque formation. Some doctors believe that psoriasis get triggered by stress, strep throat infection, smoking and exposure to cold weather. Psoriasis may repeat in cycles getting better for some days and again presenting with worse symptoms.
Very often plaque psoriasis may flare up for few weeks and then subside for returning with full vigor. You can use cream that contains Caldecort or Coraid for suppressing the bumps or lesions on the skin.
Otherwise, the medicine will have difficulty in penetrating through the thick layer of skin. The mode of treatment can be divided basically into 3 types namely topical treatment, medications and light therapy. It will not only reduce swelling caused by bumps but will also suppress the immune system which attacks the healthy skin cells. The UV rays of the sun is effective in destroying new T cells but one should be careful while taking sunbath, failing which it would cause severe sunburn.
Retinoids may cause serious side effects like birth defects and hence women who are planning for pregnancy should avoid using retinoid. Often, some environmental factor like bacterial infection is enough to activate the mutated gene causing lowered immunity. It lies on the uppermost layer of the skin in the form of brownish red spots which are called plaques. Mild cases of this disease require no treatment but it is definitely a nuisance whereas severe cases can cause intense itching and pain sometimes disfiguring the area affected. Psoriasis will not only affect the skin but also the nails disfiguring them like that of fungal infection. The method of treatment differs widely with the intensity of spread of psoriasis and the patienta€™s health condition.
Doctors would prescribe low dosage of corticosteroid for application on face and other delicate skin areas.
Anthralin is highly recommended for reducing the production of skin cells and is also effective in removing the scaly patches. Prograf and Elidel are calcineurin inhibitor are given for treating severe forms of psoriasis and is effective in reducing plaque formation. Mild doses of UVB light is emitted on the psoriasis affected areas of the skin which would control psoriasis.
Photo-chemotherapy is a process in which psoralen is allowed to penetrate the skin before it gets exposed to Ultra Violet rays, so that the skin becomes more responsive for the treatment. Hence individuals who are genetically susceptible to this disease if exposed to unfavorable environment or skin injury, it can cause plaque psoriasis.
Eventually this will lead to the production of healthy skin cells which rapidly move to the upper layer of the skin forming patches.
It would occur anywhere on the body but commonly seen on knees, elbows, and scalp and the lower back.
Tar is available in many ointments and creams and even on shampoos and hence psoriasis on scalp can be cured using medicated shampoos. You need to repeat this process of UVB therapy for 2-3 times a week for getting positive results. Between now and 2016, blockbusters with about $255 billion in global annual sales will go off patent, notes EvaluatePharma Ltd., a London research firm. But in people affected with psoriases, the immune cells produce excess of protein called tumor necrosis factor which causes rapid growth of skin cells.
The new skin cells will not wait for the dead cells to wither; instead they are formed over the dead cells causing red scaly patches called plaque. Some people recommend taking sunbath for controlling the disease but you should not overdo this method causing sunburn. However using corticosteroids for long term can produce side effects like thinning of skin. Laser therapy is also used for destroying the new T cells which is responsible for causing plaque. For the uninsured, who have been paying full price, the savings will be much bigger.Daly Powers, 25, an uninsured student who works two part-time jobs at low wages, says he often can't afford the $220 a month for his depression and attention deficit disorder pills. He couldn't buy either drug in June and says he's struggling with his Spanish class and his emotions.
Then, several other generic makers typically jump in, driving prices down dramatically.Last year, the average generic prescription cost $72, versus $198 for the average brand-name drug, according to consulting firm Wolters Kluwer Pharma Solutions. And of the top sellers that soon will have competition, Lipitor retails for about $150 a month, Plavix costs almost $200 a month and blood pressure drug Diovan costs about $125 a month.
Both are 67, and they land in the Medicare prescription "doughnut hole," which means they must pay their drugs' full cost by late summer or early fall each year. That pushes their monthly cost for Lipitor to about $95 each, and their combined monthly prescription cost to nearly $1,100.Generic Lipitor should hit pharmacies Nov. 30 and cost them around $10 each a month."It would be a tremendous help for us financially," she says. And unless the doctor writes "brand only" on a prescription, if there's a generic available, that's almost always what the pharmacist dispenses."A blockbuster drug that goes off patent will lose 90 percent of its revenue within 24 months. The dearth of successes, partly because the "easy" treatments have already been found, has turned the short-term prognosis for "big pharma" anemic."The profit dollars that companies used to reinvest in innovation are no longer going to be coming," warns Terry Hisey, life sciences leader at consultant Deloitte LLP's pharmaceutical consulting business.
Eventually, those will help fill the revenue hole.For now, brand-name drugmakers are scrambling to adjust for the billions in revenue that will soon be lost.
Typically, they raise prices 20 percent or more in the final years before generics hit to maximize revenue.
Those include vaccines, diagnostic tests, veterinary medicines and consumer health products.As the proportion of prescriptions filled with generic drugs jumped to 78 percent in 2010, from 57 percent in 2004, annual increases in prescription drug spending slowed, to just 4 percent in 2010.
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