The Division of Metabolism, Endocrinology & Diabetes (MEND) offers comprehensive inpatient and outpatient services and educational programs in the general area of endocrine and metabolic disorders. The University of Michigan Health System Web site does not provide specific medical advice and does not endorse any medical or professional service obtained through information provided on this site or any links to this site. Problems with body temperature, such as heavy sweating at night or when you eat certain foods; some people may have reduced sweating, especially in their feet and legs. Heart and blood vessel problems, leading to poor circulation or low blood pressure; this may cause dizziness, weakness or fainting when you stand or sit up from a reclining position. Your doctor will check how well you feel touch and temperature and will test your strength and your reflexes. Sexual problems may be helped with medicines or devices to improve erections or with lubricating creams that help vaginal dryness. Our research team comprises Kovler faculty as well as University of Chicago faculty working in diabetes-related research areas, including genetics and epidemiology, immunology, islet biology, signal transduction, obesity, sleep and stem-cell biology. Explore our team: Please select one or multiple filters and deselect any filters you wish to not use.
Be the first to hear about Kovler family events, research studies, classes, research and new discoveries. This presentation was developed under tho guidance of Victor Lawrence Roberts, MD, MBA, FACP, FACE, Professor of Internal Medicine, University of Central Florida, College of Medicine, Orlando, FL. Tests such as electromyogram and nerve conduction studies may be done to confirm the diagnosis. You may need other tests to see which type of neuropathy you have and to help guide your treatment. Also mention heavy sweating or dizziness and any changes in digestion, urination, and sexual function. The older you get, and the longer you have diabetes, the more likely you are to have nerve damage. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. Brancati, an internationally known expert on the epidemiology and prevention of type 2 diabetes who was director of the Division of General Internal Medicine at the Johns Hopkins University School of Medicine, died Tuesday of amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, at his Lutherville home. While traditional patient safety methods for dissecting medical errors focus on faulty systems, such methods are often less useful in cases of diagnostic error, and a broader cognitive framework is needed to ensure a comprehensive analysis of these complex events. The fishbone diagram is a widely utilized patient safety tool that helps to facilitate root cause analysis discussions. Brancati succeeded as division chief."He could have been a stand-up comedian or an author along the lines of Bill Bryson," he said. This tool was expanded by the authors to reflect the contributions of both systems and individual cognitive errors to diagnostic errors. Along with improvements in the safety of healthcare systems, there has emerged an increasing appreciation of the importance of diagnostic error in causing patient harm [2, 3]. Appel, director of the Welch Center for Prevention, Epidemiology, and Clinical Research at Johns Hopkins."He was really an amazing person who had so many dimensions to him.
Studies suggest an overall diagnostic error rate as high as 8%a€“15% with 17% of adverse events in hospitalized patients being attributable to diagnostic error [4, 5]. He had an amazing attitude and really cared about people of all spectrums throughout Hopkins. Yet despite the high prevalence and increasing profile of diagnostic errors, the best means of preventing and responding to them remains unknown [6].One source of difficulty in addressing diagnostic error is the complexity of the underlying causative factors, with one study identifying an average of six contributory factors per error [7]. Further, there exist interdependencies and interactions between the imperfect human cognition and an imperfect work environment that complicate diagnostic error conversations [8, 9].


While physicians are becoming more comfortable discussing system factors that contribute to error, many have a limited understanding of the cognitive processes that underlie the diagnostic method and less comfort in acknowledging and learning from their own cognitive errors since they are by definition a€?personala€? as opposed to being caused by a€?the systema€?.Thus, there is a need among both medical educators and patient safety experts for a structured approach to the analysis of diagnostic errors that accounts for their high degree of complexity. Brancati came to Baltimore in 1989 for a general internal medicine postdoctoral fellowship, while also earning a master's degree in clinical epidemiology from the Bloomberg School of Public Health.He joined the medical school faculty in 1992 and was promoted to professor in 2003. A recent study has described attempts to perform root cause analyses on diagnostic errors, citing that both systems factors and a€?team cognitiona€? factors contribute to these errors [10]. However, the study does not comment on the widely acknowledged contributions of the individual cognitive processes to many diagnostic errors, as described by Croskerry [11].
Brancati's tenure, the division grew to include 80 full-time faculty, 150 part-time faculty and 17 postdoctoral fellows. Because diagnostic errors so frequently result from multiple factors, the approach to diagnostic error analysis should be comprehensive and include consideration of system-based, team-based and individual-bases cognitive factors, an approach Croskerry calls the a€?cognitive autopsya€? [12].Traditional tools used for RCA should thus be modified to accommodate the complexity of diagnostic error and include cognitive analysis.
The division also received more than $30 million per year in National Institutes of Health and other federal grants."Besides being a great scientist, what set him apart was his amazing sense of humor. He was very witty, and that helped people remember him and his ability to connect with them," said Dr. Initially described for use in quality assurance programs in the manufacturing industry, fishbone diagrams are now widely utilized as a patient safety tool to structure RCA of systems errors in hospitals and other healthcare settings [13, 14]. These diagrams facilitate the dissection of complex medical errors into discrete categories, and it was in the fishbonea€™s visual display of inter-related categories that we saw the potential application to diagnostic error. Below, we describe how the traditional fishbone diagram has been adapted and successfully used at two institutions, Maine Medical Center, and the University of Pennsylvania, as a tool to understand and learn from diagnostic error.Applications for patient safetyWithin the patient safety program at Maine Medical Center, follow-up of diagnostic errors was frequently directed to the peer review process. Increased awareness of the multi-factorial etiology of these errors led us to apply our existing root cause analysis process to such errors. Brancati had mentored many people from different backgrounds through the years, and as division chief for the last eight years, he "supported everyone."Dr.
However in doing so, we determined that the structure of the standard RCA was not likely to capture common contributors to diagnostic error such as affective bias and cognitive mistakes.Using the standard fishbone diagram as a framework, a new RCA classification schema was constructed for diagnostic errors. Brancati was respected for his mentoring of women and minorities and had been given a Johns Hopkins University Diversity Award."Everyone who worked with him would be given the opportunity to achieve their potential," she said. This reframing of the review procedure and avoidance of the one-dimensional peer review process has resulted in a more comprehensive examination of these errors and increased institutional appreciation of the complexity involved.
Brancati's Hopkins colleagues said that his research had a profound impact on our understanding of the clinical epidemiology of type 2 diabetes and its complications.Dr. As a result, multiple contributors to diagnostic errors that otherwise may have been overlooked have been identified and specific interventions have been devised to prevent recurrence. Brancati studied trends in diabetes that ranged from age, race and ethnicity in the United States.
An algorithm for the emergent evaluation of patients presenting with specific neurologic symptoms, an institutional consultation protocol and a proposed curriculum in the recognition of affective bias all resulted from this process. His research also included risk prediction for diabetes and diabetic complications."In diabetes, he had many accomplishments, including being interested in the racial disparity and differences between blacks and whites who suffered from the disease," said Dr. Recognizing that systems and cognitive factors coexist and that both interact and contribute to many, if not most, cases of diagnostic error [7], we also added a cognitive component to the fishbone diagram. We believed that the use of this visual tool, and the systematic approach needed to construct it, would be helpful to residents as they learned how to analyze diagnostic error by identifying and differentiating cognitive from systems contributing factors.
The modified fishbone diagram was introduced to our second year residents as one part of a longitudinal curriculum in cognitive bias and diagnostic error [16]. Residents worked in small groups with a faculty facilitator to identify the cognitive biases and system factors present in the case below to create a fishbone diagram adapted to the complex nature of a diagnostic error.Our overall impression is that our residents found the adaptation of this familiar tool to be illustrative, practical and intuitive.
Brancati also had many accomplishments as director of the division of General Internal Medicine."When there were hiring freezes at Hopkins, he was still able to hire, and knew how to work the system," said Dr.


Encouraged by positive informal feedback from our learners and faculty, we are also using the diagnostic error fishbone diagram to teach diagnostic and cognitive error concepts to medical students on their internal medicine clerkship. Brancati was presented the Kelly West Award for Outstanding Achievement in Epidemiology from the American Diabetes Association and the Chief of the Year Award from the Association of Chiefs & Leaders of General Internal Medicine.Dr.
Jaffee, a prominent cancer researcher who is the Dana and Albert "Cubby" Broccoli Professor of Oncology and co-director of the Skip Viragh Center for Pancreas Cancer at the Johns Hopkins Kimmel Cancer Center."I was going through Fred's wallet and he had kept our prom tickets," said Dr. The patient was diagnosed with viral gastroenteritis and diabetic ketoacidosis from insulin non-adherence.
The insulin drip was stopped and the ED physician gave report to the admitting night resident. The resident reviewed the chart and discovered that the patient had been admitted four times in the past year with similar symptoms and had delayed gastric emptying on a prior gastric emptying study.The next morning the on-call team visited briefly with the patient who was waiting for a ward bed.
The discussion was truncated because of other new admissions, but the team agreed to initiate metaclopramide and hold narcotics. Stuck on the floor in rounds and on the advice of his resident (a€?His CTa€™s negative; hea€™s probably a frequent flyer looking for drugs.
Doesna€™t he know that narcotics will worsen his gastroparesis?a€?), the intern suggested over the phone that acetaminophen be given.
After several requests for narcotic pain medication were denied, the patient left the ED against medical advice.Two days later, the patient was readmitted with lightheadedness and fatigue. A detailed history clarified that the patienta€™s most concerning symptom was fatigue, which had led to loss of his job and insurance 9 monthsa€™ previously. Further review of past records showed the potassium level was often in the mid-5 range, and 4 months ago, the patient had had an equivocal serum cortisol level drawn in the hospital. He failed to follow up with an endocrinologist because when he called to make an appointment, he was told that he had to secure insurance through medical assistance before he could be scheduled.
The physical exam on rounds discovered slightly darkened skin, which the patient noted over the last few months. Cosyntropin stimulation test confirmed a diagnosis of adrenal insufficiency.ConclusionsAlthough the degree to which diagnostic errors can be prevented is controversial and currently unknown, this uncertainty should not prevent attempts to improve diagnostic reliability. Modifying the fishbone diagram for diagnostic error analysis and education is one practical attempt that is advantaged by its concreteness and familiarity among patient safety experts and educators. We provide anecdotal reports of the utility of this approach within two centers, and hope that others will use and build upon this tool in an effort to learn and improve from their local diagnostic errors.
We note that the traditional systems-focused fishbone diagram and root cause analysis framework are limited by a lack of evidence linking it to better outcomes [17], but these widely utilized tools remain practical ways to identify and address safety hazards in healthcare. We are pleased to offer this modified fishbone diagram as a tool for a more comprehensive approach to analyzing and teaching about the complexities of diagnostic errors.AcknowledgmentsThe authors wish to acknowledge Joan M. Ogdie, MD from the Perelman School of Medicine at the University of Pennsylvania for their assistance with the medical education applications of the diagnostic error fishbone diagram.
Reilly was supported by NIH Institutional Training Grant T32-DK 07006-37 and the Center for Healthcare Improvement and Patient Safety at the University of Pennsylvania. Root cause analysis reports help identify common factors in delayed diagnosis and treatment of outpatients.
Diagnosing diagnosis errors: lessons from a multi-institutional collaborative project and methodology.
Teaching about how doctors think: a longitudinal curriculum in cognitive bias and diagnostic error for residents.



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