If you ask the average person on the street to play a word association game with diabetes, the word “fat” will come up sooner rather than later. The correlation breaks down, however, if one assumes that obesity and insulin resistance are always connected. Insulin resistance is a metabolic condition that causes the body’s cells to require a higher than normal amount of insulin to convert glucose into energy. Handelsman goes on to explain that up to 40 percent of people with insulin resistance also have a defect in their insulin-producing beta cells that prevents the pancreas from producing insulin beyond a certain level of demand.
Insulin resistance researchers have learned that an increased amount of fatty acids and inflammation from obesity causes cells to require more insulin to do the same job.
Before we begin to dwell on obesity as a principal cause of resistance, metabolism throws us a curve in that some insulin-resistant people are thin. In addition, some thin people are what is colloquially called “skinny fat,” meaning that although they may look thin on the outside, their body actually has a high percentage of body fat compared to muscle. Pre-diabetes can exist for a long time in your body without triggering the most common outward signs of diabetes (continual thirst, frequent urination, blurred vision, etc). Fortunately, there are other ways to identify insulin resistance using biomarkers in blood drawn from patients as a normal part of an annual or semi-annual general checkup. Tests showing the degree of pancreatic output and what could be defined as “pancreatic stress”. Tests that evaluate a person’s degree of inflammation.These biomarkers include a cardiac-specific C-reactive protein measurement (CRP) and a sedimentation rate. Measurements that quantify fatty acid metabolism and the fatty acids released by the patient. Metabolon exhibited its new insulin-resistance test, Quantose, at this year’s American Diabetes Association’s Scientific Sessions in Chicago.
In this video, we show a novel way to share with others what to do if you experience a low.
Parents of kids with diabetes accumulate both diabetes knowledge and wisdom as they help manage the disease every day. Insulin Nation® delivers comprehensive information about the technology and science of diabetes therapy, and curates the best, most relevant news for the 6.5 million people in the US who take insulin – the “Citizens” of Insulin Nation. Topics covered include diabetes-specific technology and medicine, the science behind a potential cure, wearable and wireless health tech, the rich data produced by meters, pumps, and CGMs, and the people and organizations that impact the everyday lives of our readers. Diabetes mellitus is a disorder wherein there occurs a deficiency in the production of insulin hormone resulting in the increase of blood sugar. Type 2 diabetes may be caused due to the increase in blood pressure and blood triglyceride levels. Insulin resistance in type 2 can be seen in conditions like obesity, pregnancy, infections and stress.
The history of the patient to find any of the hereditary aspects of the disease is carefully analyzed at the first stage. The complications that correspond the diabetic condition include diabetic hyperglycemic hyperosmolar coma and diabetic ketoacidosis. Keeping the body weight under control and maintaining a healthy lifestyle might prevent type 2 diabetes.
However, a regular check up of blood glucose level and taking right doses of medicine of insulin can reduce its severity. Women with polycystic ovary syndrome may benefit greatly from following a pcos diet and making a few simple lifestyle changes particularly regarding food and exercise.
Polycystic Ovary Syndrome (PCOS) is a medical condition that affects 10-20 percent of women who are of childbearing age.
Although the cause is unknown, many doctors believe that genetics is an important factor since it seems to run in families.
Since several of the symptoms can indicate other conditions, it is often overlooked until infertility becomes a problem. The main issue seems to be a hormone imbalance where excess male hormones, or androgens, are produced. Although women need a certain level of these male hormones, those with PCOS have so much that it interferes with ovulation and causes other symptoms such as irregular menstrual periods, facial hair growth and thinning of scalp hair.
There are several symptoms associated with PCOS; however, these can vary from woman to woman so it is important to speak with your doctor about both diagnosis and treatment.
Weight gain, obesity, or difficulty losing weight: Many women with PCOS also have insulin resistance, which can lead to both weight gain as well as difficulty losing weight. Hirsutism: Excessive hair growth in places typically associated with men, such as the face, chest, back, fingers, and toes. Insulin is a hormone that is produced by the pancreas and is very important in converting carbohydrates (glucose) to energy for the body to use.
Studies have found that women with PCOS have too much insulin because their bodies have difficulty using what the pancreas produces.
In many cases, a normal level of insulin is actually being secreted, but since the body does not respond appropriately, the pancreas is signalled to make even more.
This high level of insulin tells the body to store energy as fat, which leads to weight gain.
And, this perpetuates a frustrating cycle, since weight gain leads to an even greater level of insulin resistance, which may eventually result in Type 2 diabetes. There also appears to be a connection between excess insulin and the production of androgens, or male hormones, particularly testosterone. Although women need a small amount of testosterone, too much can cause an imbalance that leads to irregular periods, acne, weight gain, abnormal hair growth, and infertility. There are also other serious health concerns associated with insulin resistance, including high blood pressure, high cholesterol levels, heart disease, and diabetes. Following a diet for PCOS and incorporating regular exercise into your daily routine can effectively manage blood sugar levels and help reduce the risk of developing other diseases. Ovulation is difficult to predict since fluctuating hormones interfere with the ovulation process. As the egg grows, the fluid increases, and eventually the follicle will break open and release the egg. In women with PCOS, the ovaries do not produce enough hormones to allow the egg to fully mature. Follicles may begin to mature, but the stage where ovulation occurs may be postponed to a smaller or larger degree.
In a normal menstrual cycle, ovulation triggers the production of progesterone, which prepares the lining of the uterus for the fertilized egg. Besides the smaller presence (or absence) of progesterone, ovaries affected by PCOS also make male hormones, or androgens, in greater amounts than needed, which further interferes with the ovulation process. Also, many of the immature follicles may remain in the ovaries as cysts, which is why the condition is referred to as polycystic ovary syndrome.
Although it can be much more difficult, it is possible for women with PCOS to become pregnant. There are many fertility treatments available, but effectiveness may vary depending on the individual and severity of the condition. Also called a low glycemic diet or a GI diet which basically focuses around not raising the insulin level unnecessarily when eating (more about this in depth later). A Danish gynaecologist, Bjarne Stigsby, an expert on PCOS has done extensive research into the relationship between PCOS and the level of sugar food.
Many women find that weight loss will help restore hormonal balance and improve regularity of the menstruation cycle, which increases the likelihood of pregnancy. Metformin is a drug that is used quite regularly in the treatment of PCOS because it improves the body’s sensitivity to insulin. As already mentioned, studies have shown a connection between high insulin levels and the production of male hormones in women with PCOS.
The theory is that by decreasing the amount of insulin secreted, the level of male hormones will also be reduced, and ovulation may resume at a more normal frequency. Although Metformin is commonly used in patients with diabetes, it is also safe for those who have not been diagnosed with Type 2 diabetes since it works by affecting insulin levels rather than directly interfering with blood sugar. The most frequently prescribed fertility drug is Clomid, which works by increasing the production of FSH and LH. Often, Metformin is also prescribed to help reduce insulin levels and restore regular menstruation. If Clomid, or other similar drugs, are not successful, injections of FSH or LH may be given to help stimulate the ovulation process.
In Vitro Maturation (IVM) is a process that removes immature eggs from the ovary and allows them to mature in a lab. In this case, a woman is given medications that will cause the follicles to grow and mature, and when they reach the appropriate stage of maturity, they will be removed, fertilized in a lab, and replanted into the uterus. The main difference between IVM and IVF is the use of medications that lead to the production of mature eggs. In by far most cases when a woman with PCOS to becomes pregnant, she carry full-term, and delivers a healthy baby. Many factors will play a role, including the severity of the condition, the woman’s general overall health, how well PCOS has been managed, how prepared the woman was for a pregnancy, and the quality of treatment and medical care received throughout the pregnancy. With proper management and medical care, many issues can be controlled or prevented, thus increasing the likelihood of a problem-free pregnancy. Some studies have shown that women with PCOS have a somewhat higher risk of miscarriage, however, this can be greatly reduced when women are aware of the risk and take the proper precautions to maintain pregnancy. Preclampsia is a condition that involves high blood pressure and high levels of protein in the urine. Since many women with PCOS already suffer from hypertension, increased numbers during pregnancy create an even greater problem that puts both the fetus and mother at risk.
If the health of the mother or the life of the baby is in great enough danger, then labor may be induced or a cesarean section may be performed. Women with PCOS are also at a greater risk of suffering from hypertension (high blood pressure) without the complications of preclampsia, so this should be monitored regularly to ensure a healthy pregnancy. This is a form of diabetes that appears during pregnancy and disappears following delivery.
Since PCOS is often associated with diabetes, women suffering from this syndrome are at an even greater risk of developing such complications during pregnancy.
If gestational diabetes occurs, women must eliminate sugar from their diet and be monitored closely for any potential problems.
In some cases, premature delivery may be induced due to other complications, but women with PCOS will often go into early labor on their own. Today’s technology makes survival of premature births much more likely, but both the baby and mother will be monitored closely. Promising studies have shown that metformin can be effective in reducing many of the problems associated with PCOS and pregnancy.
The drug appears to be safe to take during pregnancy and there is no evidence that is causes any birth defects. There is no cure for PCOS, but there are several treatments that can help reduce or minimize many of the symptoms associated with the condition. Since symptoms will vary greatly from woman to woman, treatment will be decided on an individual basis. Many factors will be considered including symptoms, risk for specific complications such as heart disease or diabetes, and whether or not there is a desire to become pregnant. Most women find that a combination of lifestyle changes, natural remedies, and medical treatments works the best to help combat the symptoms of PCOS. It may also take some time and experimentation to discover what works for each individual, and treatments may need to be adjusted as the body ages or goes through hormonal changes. Weight gain or obesity is often associated with PCOS, and this can lead to other health problems such as heart disease, type 2 diabetes, or infertility. Studies have shown that losing as little as 10% of body weight can help restore ovulation and normal menstrual cycles, improve the chances of pregnancy, and greatly reduce the risk of serious disease. From years of study and experimentation, it seems that a low glycemic diet, the basis of a PCOS diet, has been one of the most successful approaches to weight loss for women with PCOS. The low glycemic diet, or the GI diet, was designed specifically for diabetics as a means of controlling blood sugar and reducing excess insulin production. Since the weight gain experienced with PCOS is connected to insulin metabolism, the GI diet is a good choice for managing the symptoms.
Eat low glycemic grains such as quinoa, barley, buckwheat, brown rices, dark, heavy bread and millet. Eat two servings of fruit a day, but try to make low-GI choices such as berries, oranges, or cherries.
Choose healthy fats such as olive oil, avocado oil or nuts and avoid processed fats or products containing hydrogenated oils. While the low glycemic diet has been very successful for many women suffering from PCOS, it does not work for everyone.
Some people have found that a vegan diet is much more effective, and others enjoy results by counting calories or joining a diet club or support group that encourages them to stay on track and helps them to overcome discouragement. Whatever method is chosen, the key to aim for a balanced diet that consists of mainly low GI foods and is free of processed foods and added hormones. While there is no scientific proof that supplements can actually cure PCOS, some natural treatments can help restore balance to the body or improve systemic functions so that the condition also improves. Certain remedies are shown to be effective in lowering testosterone levels, increasing the likelihood of ovulation, and aiding in weight loss. Again, keep in mind that each body will responds differently to treatments, so all the supplements listed will not work for everyone.
Even though these herbs are natural, it is still important to speak with your health care provider to make sure that they are safe for your particular situation.
If you are wanting to become pregnant, these supplements should only be taken until pregnancy occurs, and then discontinued until after delivery unless your doctor tells you that they pose no risk to the baby.
You should also speak with your doctor about the safety of any supplements while breastfeeding. Chromium: This is a trace mineral that may help balance blood glucose levels, improve insulin sensitivity, and aid in weight loss.
Cinnamon: Cinnamon is a popular supplement used to balance blood glucose levels and control appetite. N-acetyl-cysteine (NAC): This is an antioxidant that has been found to help reduce insulin resistance, lower testosterone levels, and increase the chances of ovulation and pregnancy in women with PCOS when combined with other fertility drugs. Chasteberry: Vitex, or chasteberry, is one of the most popular PCOS supplements due to its ability to balance reproductive hormones.
Inositol: Inositol is part of the vitamin B family and is used to reduce testosterone levels, improve insulin sensitivity, reduce acne, and lower unwanted hair growth. Vitamin D: Vitamin D deficiency has been linked to insulin resistance, weight gain, liver problems, and irregular menstruation.
Stinging Nettle Root, Licorice Root, Ground Flax Seed: All three of these substances are thought to decrease testosterone levels in women with PCOS, and possibly also help increase the production of female reproductive hormones. Biotin: Biotin is a type of B vitamin that aids in glucose metabolism, nervous system health, and the growth of skin and nails. Black Cohosh: This herb is often used to lower blood pressure and manage symptoms of PMS or other menstrual cycle related issues. Dong Quai: The root of this plant has very strong medicinal properties and is useful for restoring irregular menstrual cycles and controlling the symptoms of PMS. Not only will regular exercise help women with PCOS lose or maintain weight, it has also been shown to improve insulin resistance. Plus, exercise will improve mood and help increase the chances of a healthy, full-term pregnancy. Remember, just a 10% loss of body weight can improve the symptoms of PCOS, and exercise is a great way to achieve this goal.
Many women with PCOS have found that taking birth control pills can help restore normal menstrual cycles, reduce male hormone levels, clear acne, and decrease the amount of facial hair.
As previously mentioned, Metformin is a drug used to treat people with type 2 diabetes, but it is also often prescribed to women with PCOS. Since many of the symptoms of PCOS are associated with insulin resistance, there has been a lot of support for using metformin as a form of PCOS treatment, although it is not approved for this use in many countries. Although ovarian drilling is considered to be a fertility procedure that can restore normal ovulation, it has also been shown to lower the male hormone levels that are often the cause of many other PCOS symptoms. Unfortunately, these benefits may only last a few months, so the surgery will need to be repeated. Ovarian drilling does not deal with all the other symptoms associated with PCOS, particularly weight gain or abnormal hair growth; although some improvements of these conditions may be noticed if the benefits of normal ovulation and male hormone reduction last for an extended period of time.
These are drugs that are designed to help reduce the production of male hormones, thereby reducing unwanted hair growth and other symptoms caused by an overproduction of androgens.
This treatment is often given in conjunction with birth control pills; however, neither medication can be used while pregnant or breastfeeding. While the effectiveness of acupuncture for PCOS is controversial, many women have found that it helps restore regular ovulation and improves the likelihood of pregnancy.
Further studies need to be done before a conclusion can be made regarding acupuncture as a treatment for reproductive disorders, but similar to natural remedies, the results are very individualized and, despite criticism, some women are experiencing very positive results. Some women find that counselling, psychotherapy, or even support groups can help them cope with the condition and teach them how to manage PCOS effectively. Simple cosmetic procedures such as laser hair removal or electrolysis can help remove abnormal hair and improve confidence or a sense of well-being. Many studies have shown that a low glycemic diet, a PCOS diet, physical exercise and weight loss are the best ways to improve insulin resistance and reduce the symptoms of PCOS.
Also certain supplements have been found to be successful; however, care should be taken when using any herbs or vitamins, particularly if you are wanting to become pregnant or if you are breastfeeding your baby. Turmeric has a wide range of antioxidant, antiviral, antibacterial, antifungal, anticarcinogenic, antimutagenic and anti-inflammatory properties.
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Stay up-to-date with Holistic Health Naturally by signing up for our free weekly newsletter. Center for Disease Control, 100 million Americans are now obese, with a Body Mass Index (BMI) of 30 or higher.
Besides having a predisposition to diabetes, insulin-resistant people may have other health issues, too, including high blood pressure, high cholesterol, heart disease, and polycystic ovarian syndrome (PCOS), a leading cause of infertility issues.
This “insulin max” is different for every affected individual, but ultimately an individual pancreas reaches its maximum insulin output and then starts to “burn out.” Over time, those affected will need medications, including injected or infused insulin, to cope with the problem of excess glucose in the bloodstream.
Losing weight and increasing activity can mitigate this, but the genetic predisposition to insulin resistance is beyond a person’s control. Doctors theorize that the genetic beta cell defect predisposition is much higher in this group. And standard methods of detecting insulin resistance or pre-diabetes using glucose tolerance tests or an A1C percentage often show false negatives; that’s because the pancreas is still able to produce enough insulin to overcome insulin resistance. These biomarker data can be plotted against what is considered normal, and as a result, place the person at a specific point along the path to pre-diabetes or to Type 2 diabetes itself. These biomarkers can give insight into a person’s unique communication between fat metabolism and insulin. Quantose is a blood test for certain biochemical markers that are associated with insulin resistance, which can inform a patient of their level of risk for Type 2 diabetes. Before asking for a test, however, it pays to call your insurance provider to see what’s covered, as the tests are expensive, says Dr.
Diabetes mellitus type-2 is one such disease relating to high blood glucose due to insulin resistance.
Consumption of fatty foods and alcohol intake at a higher level would also result in such disease. Insulin treatment with a syringe of insulin pump and oral medicines decrease the levels of blood sugar.
Long term complications include coronary artery disease, diabetic neuropathy, hypertension, skin infections, stroke, peripheral vascular disease and atherosclerosis.
Low alcohol consumption and quit smoking would ideally be suggested as the best preventive measures. We examined the restoration of first-phase and total insulin response as well as hepatic and peripheral insulin sensitivity.
However, many women do not even realize that they have PCOS until they have difficulty becoming pregnant.
In fact, PCOS is the leading cause of infertility in women – mainly because it often goes unnoticed.
However, since ovulation does not always occur in women with PCOS, progesterone is not secreted, and this causes irregular, or even absent menstruation.
His overall conclusion is that if women change their diet to a much lower GI than the typical diet of the western world today, they may get pregnant much quicker than what would normally otherwise be the case.
While there has been some success, only about 30-40% of women with PCOS will become pregnant when using fertility drugs alone. This current destroys a tiny portion of the ovary and is sometimes successful in lowering the production of male androgens and restoring more regular ovulation. Once maturation is reached, the eggs are fertilized and implanted into the woman’s uterus. While IVF is the more common procedure, IVM is a great alternative for women who do not respond well to drug therapy. However, it is passed through breastmilk, so if you plan to breastfeed, you should talk to your doctor before continuing treatment. It can be very frustrating, especially since many of popular diets do not really address issues of insulin resistance, which is the main underlying cause of PCOS weight gain. These also take longer to digest, so you will feel full longer and be less tempted to snack.
Since hormone imbalances are often an issue with PCOS, if possible, try to purchase hormone free meats. Also, depending on your symptoms, not all herbal or natural remedies will be necessary, or even ideal, for your condition.
It is often used by diabetics, and has been shown to be quite effective in women with PCOS as well. In fact, some studies have shown that women can experience up to a 70% drop in male hormone levels when using inositol, which also improves the frequency of ovulation and increases the chances for pregnancy.
Many women with PCOS have low levels of vitamin D, and when given supplements, they have noticed weight loss, balanced glucose levels, and the return of normal menstrual cycles.
For women suffering from thinning hair, biotin may be a beneficial supplement to help improve male pattern baldness.
If you have a hard time disciplining yourself to exercise regularly, join a gym or walking club so you can socialize while also getting fit. Since a electric needle is used to send a current into the ovary, there is a small risk of scar tissue developing, so this will need to be closely monitored. Struggles about body image and infertility can impact self-esteem and put a strain on relationships.
Other lifestyle changes such as quitting smoking, limiting alcohol consumption, reducing stress, and coming to terms with your body image will also help you cope with PCOS.
They will be more personal in nature than this one as they will often refer to my own experience with PCOS. It is also contains healthy nutrients such as niacin, Vitamin C, Vitamin E, Vitamin K, sodium, potassium, calcium, copper, iron, magnesium and zinc.
Health Benefit of Turmeric – Cancer Prevention Prevent prostate cancer, stop the growth of existing prostate cancer and even destroy cancer cells.
Health Benefit of Turmeric – Arthritis Reliever Anti-inflammatory properties in turmeric are great for treating both osteoarthritis and rheumatoid arthritis. Health Benefit of Turmeric – Diabetes Control Used in the treatment of diabetes by helping to moderate insulin levels, also improves glucose control and increases the effect of medications used to treat diabetes. Health Benefit of Turmeric – Heals Wounds Natural antiseptic and antibacterial agent and can be used as an effective disinfectant.
Health Benefit of Turmeric – Improves Digestion Turmeric is helpful in treating most forms of inflammatory bowel disease including ulcerative colitis. Health Benefit of Turmeric – Natural Liver Detoxifier Detoxifies the blood through the production of enzymes and turmeric increases production of these vital enzymes. Health Benefit of Turmeric – Maintains Ideal Body Weight A component present in turmeric helps increase the flow of bile, an important component in the breakdown of dietary fat. At the same time, the CDC reports that as many as 80 million Americans were insulin-resistant, and since insulin resistance is a precursor to diabetes onset, the two numbers seem to support one another. Since testing only overweight people isn’t a diagnostic solution, heading off diabetes Armageddon in the future boils down to identifying insulin-resistant people, regardless of weight, say diabetes researchers. This fat is called visceral fat, which is harder to see and more damaging than fat directly under the skin.
Type 2 diabetes is also good at hiding itself; it is common that someone diagnosed as a Type 2 has already had the disease for five years, which makes the battle for control an uphill climb even before it begins. Margarita Ochoa-Maya, an endocrinologist and CDE in Manchester, New Hampshire, says that she often uses the Genova “preDguide” and “metSynguide” tests to identify those at risk.
IN editor Chris Leach provides insightful commentary on the need to help veteran D-parents to share what they know with the next generation.
Food products which contains zinc are split peas, egg yolk, beef liver, lima beans, almonds, walnuts and buckwheat. Additionally, to examine the mechanistic basis of observed outcomes, we quantified the change in fat content of the pancreas and liver The data are consistent with the hypothesis that the abnormalities of insulin secretion and insulin resistance that underlie type 2 diabetes have a single, common aetiology, i.e. Difficulty losing weight and facing the increased risk of serious conditions such as heart disease or diabetes can be discouraging. Multiple researchers have found that the active components in turmeric makes it one of the best protectors against radiation-induced tumors. In addition, turmeric’s antioxidant property destroys free radicals in the body that damage body cells. Another significant benefit is turmeric’s effectiveness in helping reduce insulin resistance, which may prevent the onset of Type-2 diabetes. If you have a cut or burn, you can sprinkle turmeric powder on the affected area to speed up the healing process.
However it is important to bear in mind that people suffering from any kind of gallbladder disease should not take turmeric as a dietary supplement as it may worsen the condition.
Those who wish to lose weight or treat obesity and other associated diseases can benefit from having one teaspoon of turmeric powder with every meal. Like many things connected to diabetes, simple and ubiquitous explanations almost never work.
Early identification of insulin resistance can have a major impact on the long-term prognosis of diabetes in patients, or help patients avoid the onset of diabetes altogether, but the window for early diagnosis of insulin resistance often is missed. A high body fat ratio leads to insulin resistance, even if a BMI scale puts them below 30, the number at which obesity begins. Lawrence says that many patients, including Medicare patients, have been able to get insurance coverage for the tests.
Type 2 diabetes is popularly called adult-onset diabetes or non-insulin- dependent diabetes. Apart from medications reducing obesity and following a diabetic food plan is also suggested for such disease. Washing the feet and checking blisters or infection on the feet would be some of the methods of prevention.
It also has a preventive effect against tumor cells such as T-cell leukemia, colon carcinomas and breast carcinomas. It has been found that those suffering from rheumatoid arthritis who consume turmeric on a regular basis experience much relief from the moderate to mild joint pains as well as joint inflammation. Helps repair damaged skin and may be used to treat psoriasis and other inflammatory skin conditions.
Standard tests such as A1c percentages or fasting glucose won’t always identify the problem in time to allow prevention to work. This provides a unified hypothesis to explain a common disease that previously appeared to require separate disease processes affecting the pancreas and insulin-sensitive tissues.
It may take time but if you choose that is what you really want, it is possible to get your body back into balance. Prior to the onset of spontaneous diabetes in rodents, both total pancreatic fat and islet triacylglycerol content increase sharply.
In some cases emotional disturbance might cause increase in blood pressure leading to the disease ultimately. In vitro, chronic saturated fatty acid exposure of beta cells inhibits the acute insulin response to glucose, and removal of fatty acids allows recovery of this response. The present data provide clear evidence that decreasing total pancreatic fat is associated with a return of beta cell function.
However, it is probable that the negative effect on beta cell function is exerted by toxic intermediaries such as diacylglycerol and ceramides, which change rapidly in response to acute metabolic changes, rather than by stored triacylglycerol per se, which acts as an index of fatty acid intermediary concentration.
Endless access to abundant calories from carbohydrate may be an evolutionarily novel, and thus pathology-inducing, situation. And yet everything happens only a certain number of times, and a very small number really Leave a Reply Cancel reply You must be logged in to post a comment.
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