Type 2 diabetes patients cannot fully produce or process the amount of insulin needed to maintain a healthy glucose level. This excess insulin when present year after year causes cells to become less sensitive (or resistant) to the effects of insulin.
With Obesity, Diabetes, Heart Disease, and other diseases on the rise, Americans are now becoming more conscience of what they are eating and their lifestyles. If you have diabetes, you can still enjoy alcohol as long as you practice moderation, awareness, and sound judgment. Bitter melon, scientifically known as Momordica charantia, is of the plant family Cucurbitaceae. Diabetes is a condition where the body is unable to effectively control blood glucose levels. Diabetes is a condition where the body either does not produce insulin or the cells cannot use it properly.
Banaba: A Botany Introduction Banaba, Lagerstroemia speciosa, is a tropical flowering tree native to India, the Philippines and Southeast Asia.
Women with diabetes suffer an even greater risk of developing yeast infections, as their diabetes can create the perfect conditions for recurrent problems. FDA Advisory Panel votes 8-2 in favor of an insulin dosing label update for Dexcom's G5 CGM! In February, Johnson and Johnson announced that its SGLT-2 inhibitor for type 2 diabetes, Invokana (canagliflozin), will undergo trials as a treatment for diabetic kidney disease (nephropathy). The new trial testing Invokana in nephropathy (CREDENCE) is expected to finish around February 2019, so it will be several years before we know if Invokana can ultimately be prescribed for nephropathy.
Our mission is to help individuals better understand their diabetes and to make our readers happier & healthier.
Our mission is to help individuals better understand their diabetes and to make our readers happier and healthier. The thiazolidinedione (TZD) class of oral hypoglycemics ( popularly known as glitazones) was developed in 1997 and offers a new mechanism for treatment of type 2 diabetes. The primary effect of TZDs is peripheral, with increasing insulin sensitivity and increased glucose uptake.
Because they work on insulin resistance, they have their greatest effect on the blood glucose after eating rather than the blood glucose upon waking.
Although they normally do not cause hypoglycemia when used by themselves, if used in combination with a sulfonylurea or insulin, low blood sugars may occur. The glitazones are associated with side effects such as water retention and swelling of the ankles, especially in older people.
If you take birth control pills, glitazones might make your birth control pills less effective in preventing pregnancy.
Repaglinide and nateglinide are the two drugs which are used in this, the meglitinide group of drugs. Their action is similar to that of sulfonylureas in the sense that they increase the secretion of insulin from the pancreas and are ineffective if the pancreas does not have enough capacity to secrete insulin. We discussed before that one of the problems in Type 2 diabetes was that there was a lag period between the increase in the blood glucose levels following a meal and the release of insulin from the pancreas. The meglitinides are different from the sulfonylureas in that they raise the insulin levels acting on the pancreas but through a different mechanism. Their peak action of an hour and short duration of action of about three hours is ideal for matching meals. They are ideally taken 10 to 15 minutes before meals, the dose should be skipped if a meal is skipped. Side Effects: low blood sugar, nausea, vomiting, diarrhea, muscle aches, upper respiratory infection, cold- and flu-like symptoms, headache, joint aches, and back pain. They can cause low blood sugars, but because they stimulate insulin production only if the blood sugar is high, the risk of lows is reduced. A minor problem is that people treat when they eat, so doses are taken several times a day and has to use eating as a reminder for taking the medication.


It is a skin rash or dark red raised itchy bumps caused by viral allergies and also due to pressure, sunlight, temperature etc.
Poison ivy, poison oak, and poison sumac are plants that contain an irritating, oily sap called urushiol. Insects such as honeybees, yellow jackets, hornets, wasps, and fire ants can cause allergies. Products such as moisturisers, shampoos, deodorants, makeup, colognes and other cosmetics have become part of our daily grooming habits. Many products contain milk or milk products and milk protein causes allergy in some individuals. A food allergy is an exaggerated immune response triggered by eggs, peanuts, milk or some other specific food. The fatty liver symptoms include bloating, fatigue, high blood pressure, high cholesterol, nausea, weakness, and yellow skin. FLD caused by the consumption of alcohol can occur after drinking either moderate or large amounts of alcohol. Fatty liver disease in pregnant women: In very rare cases, pregnant women have experienced fat build up in the liver, putting both mother and fetus at serious risk. People who do not drink alcohol might develop this disease due to an overgrowth of bacteria in the small intestine or due to other changes in the intestine.
In both cases, alcoholic and non-alcoholic fatty liver disease, it apparently have a connection to what you ingest. The most effective way to treat FLD is through a diet rich in fiber, minerals, and vitamins and low in sugar and saturated fat. The Fatty Liver Diet Guide, written by Dorothy Spencer, recommends a diet that will help rectify the effects of FLD. Although FLD is a very serious and prevalent problem, the negative effects of this disease can be avoided or even reversed by correcting the behaviors that caused it to developed in the first place. That is great – it means J&J is serious about fighting kidney disease and that it thinks it has a treatment for it.
Nevertheless, this is major news for Invokana, as we do not know of any other SGLT-2 inhibitors being studied for the treatment of kidney disease. The first, troglitazone was taken off the market in 1999 because of its association with hepatic toxicity.
If you have excess abdominal weight ( high waist to hip ratio), low HDL, high triglycerides, or high blood pressure, these would be good indicators that the glitazones would be good for you possibly in association with metformin, or by themselves. Blood sugar levels may show a significant reduction statistically in as little as two to four weeks, but the maximum effects are not seen until two or three months have passed. Less insulin is required to control blood sugars when glitazones are used so your doctor may reduce the doses of any other diabetes tablets or insulin which you may be taking. Besides their effect in lowering the blood glucose levels, both drugs also have notable effects on lipids.
This caused the immediate post meal blood glucose to be very high and also could possibly lead to late hypoglycemia. Like sulfonylureas, they do not work in Type 1 diabetes and require beta cells capable of producing insulin. Conversely, they are very useful in people who show high post meal levels and also have a very erratic eating timings, as they can be taken just with a meal rather than one having to take the sulfonylurea tablet some time before the meal. Those who are allergic to milk suffer vomiting, loose motions and abdominal cramps immediately after consuming milk.
When the disease manifests after a short period of heavy drinking it is referred to as acute alcoholic liver disease. The cause of fatty liver disease in pregnant women is currently unknown but is often attributed to the influence of hormones in the body. This book provides information on which foods to avoid and which to consume in order to maintain a healthy lifestyle and, specifically, to avoid storing excess fat in the liver. Knowing the causes and symptoms will allow you to be aware not only of the health of your liver but your overall health and well-being.


As a reminder, you’ve probably heard about nephropathy when your doctor or nurse has talked about long-term healthcare complications (that dreaded term) related to diabetes. Nephropathy continues to be a major unmet need in patients with diabetes, so any therapy that markedly improves kidney function would be a huge win for patients – and healthcare providers.
Although they have not been shown to cause liver damage, your doctor may ask that you check your liver functions regularly. The current data show that pioglitazone has a minimal effect on low-density lipoprotein (LDL) cholesterol levels and a favorable effect on high-density lipoprotein (HDL) cholesterol and triglyceride levels.
If sulfonylureas have failed to control your blood glucose levels, the meglitinides would rarely be effective. Some people might also experience pain in the center or right upper part of the abdomen or develop patches of dark skin, typically found on the underarm area or on the neck. Genetics play a role in fatty liver disease by determining how likely a person is to develop alcoholism and by affecting how the liver breaks down enzymes involved in the metabolism of alcohol. Engaging in an active and healthy lifestyle has many benefits, including a decreased likelihood of developing a fatty liver. So, nephropathy occurs when high blood glucose levels over time cause damage to the kidney. Call your doctor right away if you have any signs of liver disease, which include nausea, vomiting, stomach pain, lack of appetite, tiredness, yellowing of the skin or whites of the eyes, or dark-colored urine.
Rosiglitazone has a favorable effect on HDL cholesterol levels but a negative effect on LDL cholesterol levels. They are ideal for people whose fasting blood sugar is not that high, but whose HbA1c is elevated and whose blood sugars spike after meals so testing at this time is critical. This disease typically divided into two categories: disease caused by alcohol and disease found in people who drink little to no alcohol. Not everyone will experience all of these side effects but most people will suffer from most of these symptoms at some point. Chances of developing FLD increase in people who have Hepatitis C (which sometimes leads to liver inflammation), people who have an overload of iron in their blood, obese people, and people who maintain a poor diet. Although FLD is dangerous, the negative effects of the disease can be reversed by adhering to a healthy diet. Since this disease develops slowly, people will notice these symptoms more as the disease progresses and becomes worse. FLD can also be caused by autoimmune or inherited liver disease, medication, or viral hepatitis. By adhering to the guidelines set forth in this book, it is possible to reverse the damaged liver.
In a true food allergy, the immune system produces antibodies and histamine in response to the specific food.
Some forms of eczema can be triggered by substances that come in contact with the skin, such as soaps, cosmetics, clothing, detergents, jewellery, or sweat.
Serum sickness is a delayed type of drug allergy that occurs a week or more after exposure to a medication or vaccine. Left untreated, it can cause more serious problems, such as inflammation of the liver, liver cancer, and liver scarring.
In children, the most common food allergies are to: Eggs, milk, peanuts, shellfish (shrimp, crab, lobster, snails, and clams), soy, tree nuts and wheat.
People suffering from these symptoms are encouraged to seek medical help as soon as possible. If detected early, it is possible to reverse the negative effects of this disease through simple treatments.




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