Among overweight and obese patients with type 2 diabetes, daily injection of the diabetes drug liraglutide with a modified insulin pen device, in addition to diet and exercise, resulted in greater weight loss over 56 weeks compared with placebo, according to a study in the August 18 issue of JAMA. The Food and Drug Administration has approved a Novo Nordisk diabetes drug as a treatment for obesity. Obesity guidelines recommend an initial weight loss goal of 5 to 10% of start weight to improve health. Liraglutide, an injectable diabetes drug that US regulators approved last year for weight loss, helped obese people lose an average of 18 pounds (eight kilograms), a yearlong study said Wednesday. The significant role of beta cell 'hubs' in the pancreas has been demonstrated for the first time, suggesting that diabetes may due to the failure of a privileged few cells, rather than the behaviour of all cells.
Children who are overweight or obese are at increased risk for physical and socio-emotional problems. Waist circumference may therefore be a better predictor of being unhealthily overweight than body mass index, which is a ratio of height and weight. Children ages six to 11 were nearly three times as likely to be obese in 2011-2012 as they were in 1976-1980 (18 and seven percent, respectively), although the rate was generally constant between 2003-2006 and 2011-2012. Among adolescent females ages 12 to19 in 2011-2012, Asians were substantially less likely to be obese than white, black, and Hispanic females (seven percent versus 18, 21, and 24 percent, respectively). 2008-2011 estimates by state for low-income preschool-aged children are available from the Centers for Disease Control and Prevention. Through its Healthy People 2020 initiative, the federal government has set national goals to reduce the number of obese children and adolescents.
In children, obesity is defined as having a body mass index (BMI) at or above the sex- and age-specific 95th percentile, while overweight is defined as having a BMI at or above the sex- and age-specific 85th percentile.
Note: Obese is defined as Body Mass Index (BMI) at or above the sex- and age-specific 95th percentile, based on the revised CDC Growth Charts, which use nationally representative samples of children between 1963 and 1994. Note: Overweight is defined as having a Body Mass Index (BMI) at or above the sex- and age-specific 85th percentile. Follow us on Twitter, like us on Facebook, catch us on YouTube and sign up to stay current with the latest news and updates with our E-News. According to a recent published study, there is a species of good gut bacteria that can control metabolic disorders.


Bacteria called Akkermansia muciniphila makes up 3 to 5 percent of bacteria in the guts of healthy mammals.
Patrice Cani led a team of researchers at the Catholic University of Leuven in Belgium to investigate the link between good gut bacteria and the metabolism. The researchers found that when the normal levels of the good gut bacteria were restored, the levels of endocannabinoids in the intestines were increased.
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During the same period, the share of adolescents ages 12 to 19 who were obese more than quadrupled, from five to 21 percent. Children ages six to 11 were more than twice as likely to be overweight in 2011-2012 as they were in 1971-1974 (34 and 16 percent, respectively). There are also goals under development for preventing inappropriate weight gain at all ages. Obesity statistics for 1971-1974, and overweight statistics for 1971-1991, are based on BMI distributions of nationally representative samples from 1963-1970.
For data 1971-1991, BMI distributions based on nationally representative samples taken between 1963-1970. When no data is available for Mexican-Americans, Hispanics are included in other racial categories. Results of the study suggest that microbes in the gut help to control obesity and diabetes in mice.
These bacteria that digest mucus are not as prevalent in the intestines of obese mice and humans. This event triggered molecules to help control blood-glucose levels and maintain the gut's defenses against harmful bacteria.
Moderate weight loss (5 percent-10 percent) can improve glycemic control and other cardiometabolic risk factors and disorders. A 12-week "off-drug" follow-up period was included to assess treatment-cessation effects (total study length, 68 weeks). More than one in five adolescents, and one in six elementary-school-aged children, were obese, as was more than one in twelve preschoolers.


Fewer data points are available for children ages two to five, but indicate rates of obesity have fluctuated between eight and 12 percent over the past decade. During the same period, the share of adolescents ages 12 to 19 who were overweight nearly doubled, from 17 to 35 percent. Data for other years are based on the revised CDC Growth Charts, which refer to nationally representative samples of children between 1963 and 1994.
For later data, this is based on the revised CDC Growth Charts, which are based on nationally representative samples of children between 1963 and 1994. Weight loss is especially challenging for individuals with type 2 diabetes, who often experience a reduced response to weight-management pharmacotherapies compared with individuals without diabetes. Fewer data points are available for children ages two to five, but indicate rates of overweight have fluctuated between 21 and 27 percent over the past decade. Participants were also instructed to follow a reduced-calorie diet and increase physical activity for weight management. Weight loss has also been observed with liraglutide at these doses, according to background information in the article. Prevalence of overweight and obesity among us children, adolescents, and adults, 1999-2002, JAMA, 291 (23): 2847-2850.
Prevalence of overweight and obesity among us children, adolescents, and adults, 1999-2002, JAMA, 291(23): 2847-2850. Prevalence of high Body Mass Index in US children and adolescents, 2007-2008, JAMA 303(3), 242-249.
Prevalence of High Body Mass Index in US children and adolescents, 2007-2008, JAMA, 303(3), 242-249. Prevalence of obesity and trends in Body Mass Index among US children and adolescents, 1999-2010, JAMA 307(5), 483-490.
Prevalence of obesity and trends in Body Mass Index among US children and adolescents, 1999-2010, JAMA, 307(5), 483-490.



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